• Korean Journal of Veterinary Pathology
• /
• v.1 no.2
• /
• pp.153-156
• /
• 1997

This is the first recorded case of Sarcoptes scabiei in a Korean female raccoon confirmed by light and scanning electron microscopies. Grossly the skin on the abdomen head and legs was markedly thickened with alopecia and encrustation. histopathologically skin showed epidermal hyperplasia with spongiotic degeneration and parakeratosis. Ectoparasites were present in superficial and deep epidermal layers. Small numbers of leukocytes predominantly neutrophils were associated with the parasitic infestation. Scanning electron microscopy examination of affected skin scraping demonstrated round to oval parasitic mites measuring approximately 180 -250 x 220 - 350 um in size. The mites possessed four pairs of legs of which the two anterior pairs appeared relatively long with unjointed stalks while the two posterior leg pairs were rudimentary. these morphological features were consistent with Sarcoptes scabiei.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.24 no.4
• /
• pp.533-542
• /
• 2010

Skin aging is a natural phenomenon. There are internal and external factors of skin aging. The internal factor of skin aging is from the wearing down of the body over time. The external factors are more noticeable from habits such as smoking, excessive alcohol, malnutrition, and extended exposure to UV rays. Completely stopping skin from aging is impossible but one can slow down and treat external signs of skin aging. In western medicine, the following methods are used to reduce the appearance of skin aging: applying lotions and creams containing ingredients such as fruit acid, antioxidants, plant exracts, depigmentation, moisturizer, retinoids, and sun block; botulinum toxin injections; chemical peels, laser and other painful methods remove the top layer of skin to promote new skin growth; fillers are injected to increase soft tissue growth; surgery. In oriental medicine, the following methods are used: acupuncture into facial muscles which stimulates acupuncture point; applying topical treatments and cosmetics containing herbs are effective of preventing skin aging and wrinkles. Above all thing, medicine that helps maintain essence and blood in the skin can be fundamental.

• Journal of dental hygiene science
• /
• v.13 no.3
• /
• pp.354-357
• /
• 2013

Verruca vulgaris is one of the most frequent lesions of the skin. Evidences support that this lesion has strong association with low-risk human papillomavirus. Unlike skin lesion, oral verrucae vulgaris are not easily encountered and often misdiagnosed as squamous papilloma. Herein, we reported eight cases of oral verruca vulgaris and analyzed their clinicopathological features.

• Proceedings of the Korean Society of Veterinary Pathology Conference
• /
• 2002.11a
• /
• pp.81-85
• /
• 2002

Dogs are laid on their left sides (Puppies may be placed on their back). 1. Lift the right forelimb, insert the knife in the axillary region, and cut its muscular attachment to thorax. Reflect the limb dorsally until it lays flat on the table. 2. Lift the right hindlimb, cut the inguinal area skin and the adductor muscles, and disarticulate the coxofemoral joint. Reflect the limb dorsally until it lays flat on the table. 3. A midline skin incision is made from the symphysis of the mandible to the anus, circumventing the umbilicus and male external genitalia. (omitted)

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.24 no.1
• /
• pp.85-90
• /
• 2010

Several studies have demonstrated that ginseng-berry extract has several beneficial properties, including anti-inflammatory, antioxidant, and vasodilation properties. Ginseng-berry extract has also been shown to have the great potential against skin aging. Its beneficial mechanism against skin aging, however, has not been examined in detail. Also, the effects of ginseng-berry extract on microcirculation and skin cellular responses have not been investigated. Inhibition of skin microcirculation is the primary cause of many adverse biological effects, which is responsible for the skin aging and darkening. We investigated the beneficial effects of ginseng-berry extract on blood circulation, transcutaneous oxygen pressure in vivo model and also on skin microcirculation, cellular response and skin brightening effect in clinical trial. We found that oral administration of ginseng-berry extract markedly increased blood flow rate and transcutaneous $O_2$ pressure, but decreased transcutaneous $CO_2$ pressure. Also, it improved skin tone on cheeks, as is skin brighteness. These results suggest that ginseng-berry extract is a potent candidate for the treatment of skin aging and brightening by improving skin microcirculation.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.32 no.4
• /
• pp.271-276
• /
• 2018

The purpose of pilot clinical trial is to evaluate the efficacy and safety of acupuncture therapy on TEWL(Transepidermal Water Loss) and skin hydration. A total of 36 human who visited Dongshin University Oriental Medical Center from October 2nd, 2015 to July 31st, 2016 were included in the pilot clinical trial. Acupuncture therapy was performed at Gokji(LI11) and Daechu(GV14). We observed change of TEWL(Transepidermal Water Loss), skin hydration before and after acupuncture therapy. In the primary endpoint, index of TEWL showed a statistically significant decline($8.01{\pm}2.55{\rightarrow}6.58{\pm}1.97g/h/m2$, $7.40{\pm}2.65{\rightarrow}4.99{\pm}1.89g/h/m2$). Index of skin hydration showed statistical significance($52.83{\pm}6.53{\rightarrow}56.82{\pm}7.24$, $63.50{\pm}8.57{\rightarrow}64.96{\pm}8.48$). To evaluate the safety, vital sign check were conducted and showed no statistically significant result. And there were no severe adverse events during this study. According to the above pilot clinical trial, it is suggested acupuncture therapy were effective for skin moisturizing.

• The Plant Pathology Journal
• /
• v.25 no.3
• /
• pp.291-293
• /
• 2009

The low virus titer in woody plant tissues and the presence of inhibitor compounds such as polyphenols, tannins and polysaccharides are common difficulties that compromise purification of plant viroids from their woody hosts. A simple, reliable method of RNA isolation using CF11 cellulose column on a microcentrifuge tube scale for detecting Apple scar skin viroid (ASSVd) in apple was developed. Total RNA extracted from leaf, woody bark and the fruit skin was used for reverse transcription. RT-PCR products could be detected from RNA prepared from dormant woody bark, fruit skin and fresh leaves with both the CF11 cellulose column method and NucliSens extractor in February, August and November. Meanwhile, with the RNeasy kit RT-PCR, products were detected only in leaves and not from bark or fruit skin. The PCR product, about 330 base pairs, was analyzed by agarose gel electrophoresis. The CF11 cellulose column method was effective for detecting ASSVd. The method enabled the processing of a large numbers of samples of dormant woody bark, leaf and fruit skin of apple.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.2
• /
• pp.561-567
• /
• 2005

We statistically analyzed the relationship between the constitution and the thickness and stiffness of skin depending on sex and age, using 1079 clinical data registered to SCIB(Sasang constitution Information Bank), and the following results are obtained : The thickness of skin has big discrimination ability in classification of Taeeumin and Soyangin, especially in women and in ages 21 or more. The stiffness of skin also has big discrimination ability in classification of Taeeumin and Soeumin, especially in Taeumin women and Soeumin man and in ages 21-60. The differences stated above have been proved to be meaningful enough by Chi-square test.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.2
• /
• pp.536-543
• /
• 2005

We statistically analyzed the relationship between the constitution and the refineness and tactile of skin depending on sex and age, using 1079 clinical data registered to SCIB(Sasang constitution Information Bank), and the following results are obtained: The thickness of skin has big discrimination ability in classification of Taeeumin and Soyangin, especially in women and in ages 21 or more. The stiffness of skin also has big discrimination ability in classification of Taeeumin and Soeumin, especially in Taeumin women and Soeumin man and in ages 21-60. The differences stated above have been proved to be meaningful enough by Chi-square test.

• The Korean Journal of Cytopathology
• /
• v.16 no.2
• /
• pp.93-97
• /
• 2005

Merkel cell carcinoma (MCC) is a rare primary cutaneous neuroendocrine carcinoma which commonly presents as a skin nodule, and can develop into regional lymph node metastases, as well as spread systematically. Here, we describe the cytological features of a touch imprint of MCC that arose on the face of a 62-year-old female. This touch imprint was acquired from an incisional biopsy specimen which had been submitted for frozen section. The touch preparation produced a highly cellular imprint of loosely cohesive groups of small- to medium-sized malignant cells exhibiting uniform round to oval nuclei, delicate nuclear membranes, fine chromatin, small nucleoli, and scanty cytoplasm, with occasional paranuclear button-like inclusions. We applied cytokeratin 20 to the touch imprint for immunochemistry, allowing us to visualize the tumor cells with paranuclear dot-like positivity. Both the cytological and immunocytological features were quite distinct.