• The Journal of Korean Society for Radiation Therapy
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• v.18 no.2
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• pp.89-96
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• 2006

Purpose: To study effectiveness of heterogeneity correction of internal-body inhomogeneities and patient positioning immobilizers in dose calculation, using images obtained from CT-Simulator. Materials and Methods: A water phantom($250{\times}250{\times}250mm^3$) was fabricated and, to simulate various inhomogeneity, 1) bone 2) metal 3) contrast media 4) immobilization devices(Head holder/pillow/Vac-lok) were inserted in it. And then, CT scans were peformed. The CT-images were input to Radiation Treatment Planning System(RTPS) and the MUs, to give 100 cGy at 10 cm depth with isocentric standard setup(Field Size=$10{\times}10cm^2$, SAD=100 cm), were calculated for various energies(4, 6, 10 MV X-ray). The calculated MUs based on various CT-images of inhomogeneities were compared and analyzed. Results: Heterogeneity correction factors were compared for different materials. The correction factors were $2.7{\sim}5.3%$ for bone, $2.7{\sim}3.8%$ for metal materials, $0.9{\sim}2.3%$ for contrast media, $0.9{\sim}2.3%$ for Head-holder, $3.5{\sim}6.9%$ for Head holder+pillow, and $0.9{\sim}1.5%$ for Vac-lok. Conclusion: It is revealed that the heterogeneity correction factor calculated from internal-body inhomogeneities have various values and have no consistency. and with increasing number of beam ports, the differences can be reduced to under 1%, so, it can be disregarded. On the other hand, heterogeneity correction from immobilizers must be regarded enough to minimize inaccuracy of dose calculation.

• Journal of Family Resource Management and Policy Review
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• v.19 no.3
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• pp.1-16
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• 2015

The purpose of this study was to synthesize the results of studies on the effects of multi-cultural education program for Korean children. Using the author's own selection criteria, 17 studies were finally selected and 31 effect sizes were calculated from these studies and used for meta analysis. The overall effect size for all studies on the random effect model was .802, and it was positive and high. Given the heterogeneity among the effect size, subgroup analysis was conducted. According to the analysis, effect sizes significantly differed depending on program goal, concerned multi-cultural higher than others. Result also showed that the high scored effect sizes were the general family, pre-school age children group, and the program were 11-20 children group in size, and 11~20 times in frequency of education.

• The Journal of Korean Physical Therapy
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• v.32 no.5
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• pp.277-282
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• 2020

Purpose: The main purposes of this study are to identify the degree of effect size and variables related to it, on the effect of physical therapy on shoulder adhesive capsulitis. Methods: This study were collected 8 studies published between 2010.01.01. and 2020.08.01. The Analysis result confirmed 16 effect size data, the random effect model was chosen because of the heterogeneity of the data. Results: First, full case showed the largest mean effect size 3.28 (p<0.001). Second, Size of the effect according to hands on+off intervention the 5.17 (p>0.344). Third, Number of participants showed 15 or more effect size 4.19 (p<0.002). intervention period showed 8 weeks effect size 5.12 (p>0.425). Number of intervention showed 14 or less effect size 3.99 (p>0.061). Publication type showed thesis effect size 4.34 (p<0.003). Finally, 'Trim and Fill' result confirmed that the calibration effect size is 1.71 (p<0.001). Conclusion: We were able to confirm that physical therapy had great effect on shoulders adhesive capsulitis, and that the effect differed according to the methods of intervention, the methods of evaluation.

• The Journal of Korean Physical Therapy
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• v.32 no.4
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• pp.222-227
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• 2020

Purpose: The primary purposes of this study were to identify the degree of the effect size and the variables related to it on the effects of physical therapy on myofascial pain syndrome. Methods: This study collected 15 studies published between 2008.01.01 and 2019.12.31. The Analysis results confirmed 57 effect size data. The random-effect model was chosen because of the heterogeneity of the data. Results: First, the full case showed the largest mean effect size of 2.03 (p<0.001). Second, the size of the effect, according to the handson intervention, was 2.74 (p<0.003). Third, the VAS showed an effect size of 2.30 (p<0.001). Fourth, the intervention period showed a 1- to 15-day effect size of 2.94 (p<0.001). The number of interventions showed a 6 to 10 effect size of 2.84 (p<0.006). The number of participants showed a 10 or less effect size of 2.66 (p<0.001). Finally, the 'Trim and Fill' result confirmed that the calibration effect size was 0.93 (p<0.001). Conclusion: Physical therapy had a great effect on myofascial pain syndrome in the neck and shoulders, and that the effect differed according to the methods of the intervention and the methods of evaluation.

• Journal of Periodontal and Implant Science
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• v.29 no.4
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• pp.963-979
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• 1999

This study examined ribotypes of 36 P. gingivalis strains isolated from 10 rapidly progressive periodontitis patients in Korean and revealed the presence of genetic heterogeneity among the patients. Ribotyping was performed by using a oligonucleotide probes based on 16S rRNA after whole genomic DNA had been digested with the restriction endonuclease enzyme Kpn I and Pst I. In addition, the antigenic heterogeneity of fimbrillin and protease activity was analysed to observe the virulency of P. gingivalis. The results were as follows. 1. Using KpnI, 6 ribotypes were detected, whereas 7 ribotypes were identified by using PstI. When combined two enzymes, a total of 8 ribotypes was subgrouped. 2. Ribotype I/e was the most common and detected in 4 among 10 patients. 3. The fimbrillin expressed from P. gingivalis isolates had the molecular size of 41kDa, 43kDa, 49kDa. It was observed that the size of fimbrillin with the same ribotypes could be identical. 4. All the P. gingivalis strains showed strong proteolytic activity and had the molecular size more than 120kDa. In summary, total 8 ribotypes were observed for isolates from rapidly progressive periodontitis patients. Forty percent of the patients harbored isolates exhibiting the same ribotype I/e, and it was observed that more than one ribotype can coexist in an individual patient.

• The Journal of Korean Academic Society of Nursing Education
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• v.23 no.1
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• pp.15-26
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• 2017

Purpose: This study evaluated the efficacy of a communication ability enhancement program for nursing students in Korea through a systematic review of literature and meta-analysis. Methods: The researchers searched data-bases, including the Data Base Periodical Information Academic, Research Information Sharing Service, National Digital Science Library and National Assembly Library. The key words used included 'communication' and 'nursing student'. The researchers evaluated articles published up to July 2016. Out of 381 selected articles, 20 clinical trial studies were meta-analyzed. Each article was evaluated in accordance with the Checklist of Scottish Intercollegiate Guideline Network. The effect size of communication ability, self-efficacy and interpersonal relations were synthesized by a random effects model from analysis software (R 3.2.3). The heterogeneity of effect size was analyzed by exploratory and confirmatory moderator analysis. Results: The overall effect size of the program was of a moderate level (SMD=0.78, 95% CI: 0.49~1.07) along with each outcome of self-efficacy (SMD=0.80, 95% CI: 0.23~1.37), and interpersonal relations (SMD=0.47, 95% CI: 0.14~0.80). For heterogeneity, moderator analysis was performed, by grade, and a statistically significant moderator was found. Conclusion: It is evident that a communication ability enhancement program for nursing students is moderately effective in improving communication ability, self-efficacy and interpersonal relations.

• Human Ecology Research
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• v.55 no.3
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• pp.289-301
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• 2017

This study was to analyze the effects of the career education program for students with disabilities. The analysis was performed based on two research questions. First, the total effect size on the career program for students with disabilities was considered. Second, the difference of the effect size between the sub-groups regarding dependency variables, types of disabilities, types of schools, number of people, and number of sessions was also included for analysis. For this, the author reviewed a database and analyzed 12 previous studies, presented in five master thesis and seven Korean journals from 2005 to 2015 based on the author's selection criteria. Subsequently, 27 effect size was found. The publication bias was analyzed by Rosenthal's fail-safe N. The overall effect size for all studies on the random effect model was 1.717, which was positive and high in value. Given the heterogeneity among the effect size, the subgroup analysis was conducted, and indicated that the effect size was significantly high when the purpose of the program was related to the student's self-decision ability. The results demonstrated that the programs were specified for students with intellectual disabilities, when the schools were elementary, when the number of students in a group was 1-10, and when program sessions lasted more than 21 times, the effect size was high. Implication for the future research and program implication were discussed on these findings.

• Journal of the Korean Society of Physical Medicine
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• v.15 no.4
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• pp.21-28
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• 2020

PURPOSE: The main purpose of this meta-analysis study was to identify the degree-of-effect size and the variables for the effects of manual physical therapy on myofascial pain syndrome. METHODS: This study collected six studies published between 2015.01.01 and 2019.12.31. The analysis result verified nine effect size data. The random-effect model was chosen because of the heterogeneity of the data. RESULTS: First, the full case showed the largest mean effect size of 2.297 (p < .001). Second, the size of the effect based on the fascial distortion model (FDM) intervention showed an effect size of 4.654 (p < .001). Third, the number of participants showed a 15 or less effect size of 2.612 (p > .058). The number of treatments showed a 10 less effect size of 2.844 (p > .129). The publication type showed a thesis effect size of 3.095 (p < .002). CONCLUSION: Manual physical therapy has a great effect on myofascial pain syndrome in the neck and shoulders, and that the effects differ according to the methods of intervention.

• Advances in nano research
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• v.7 no.3
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• pp.169-180
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• 2019

Plasmonic effects of gold and platinum alloy nanoparticles (Au-Pt NPs) and their comparison to size was studied. Various factors including ratios of gold and platinum salt, temperature, pH and time of addition of reducing agent were studied for their effect on particle size. The size of gold and platinum alloy nanoparticles increases with increasing concentration of Pt NPs. Temperature dependent synthesis of gold and platinum alloy nanoparticles shows decrease in size at higher temperature while at lower temperature agglomeration occurs. For pH dependent synthesis of Au-Pt nanoparticles, size was found to be increased by increase in pH from 4 to 10. Increasing the time of addition of reducing agent for synthesis of pure and gold-platinum alloy nanoparticles shows gradual increase in size as well as increase in heterogeneity of nanoparticles. The size and elemental analysis of Au-Pt nanoparticles were characterized by UV-Vis spectroscopy, XRD, SEM and EDX techniques.

• The Korean Journal of Nuclear Medicine
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• v.32 no.1
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• pp.32-49
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• 1998

For estimation of regional myocardial blood flow with O-15 water PET, a few modifications considering partial volume effect based on single compartment model have been proposed. In this study, we attempted to quantify the degree of heterogeneity and to show the effect of tissue flow heterogeneity on partition coefficient(${\lambda}$) and to find the relation between perfusable tissue index(PTI) and ${\lambda}$ by computer simulation using two modified models. We simulated tissue curves for the regions with homogeneous and heterogeneous blood flow over a various flow range(0.2-4.0ml/g/min). Simulated heterogeneous tissue composed of 4 subregions of the same or different size of block which have different homogeneous flow and different degree of slope of distribution of blood flow. We measured the index representing heterogeneity of distribution of blood flow for each heterogeneous tissue by the constitution heterogeneity(CH). For model I, we assumed that tissue recovery coefficient ($F_{MME}$) was the product of partial volume effect($F_{MMF}$) and PTI. Using model I, PTI, flow, and $F_{MM}$ were estimated. For model II, we assumed that partition coefficient was another variable which could represent tissue characteristics of heterogeneity of flow distribution. Using model II, PTI, flow and ${\lambda}$ were estimated. For the simulated tissue with homogeneous flow, both models gave exactly the same estimates, of three parameters. For the simulated tissue with heterogeneous flow distribution, in model I, flow and $F_{MM}$ were correctly estimated as CH was increased moderately. In model II, flow and ${\lambda}$ were decreased curvi-linearly as CH was increased. The degree of underestimation of ${\lambda}$ obtained using model II, was correlated with CH. The degree of underestimation of flow was dependent on the degree of underestimation of ${\lambda}$. PTI was somewhat overestimated and did not change according to CH. We conclude that estimated ${\lambda}$ reflect the degree of tissue heterogeneity of flow distribution. We could use the degree of underestimation of ${\lambda}$ to find the characteristic heterogeneity of tissue flow and use ${\lambda}$ to recover the underestimated flow.