• Journal of Platform Technology
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• 제9권4호
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• pp.79-89
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• 2021

본 논문은 사물인터넷 국제 표준 oneM2M을 활용하여 미세먼지(PM10)와 초미세먼지(PM2.5) 측정 플랫폼을 이동식과 고정식으로 설계하였다. 미세먼지 측정 플랫폼은 미세먼지 측정 디바이스, 에이전트, oneM2M 플랫폼, oneM2M IPE, 모니터링 시스템으로 구성하고 설계하였다. 이동식과 고정식의 주요 차이는 이동식은 LTE 연결을 기반으로 사각지대 없이 디바이스와 서비스간에 상호연결을 위해 MQTT 프로토콜을 사용하였고, 고정식은 저전력과 넓은 통신범위를 가진 LoRaWAN 프로토콜을 사용하였다. 미세먼지뿐만 아니라 일상생활과 연관된 온도, 습도, 대기압, 휘발성 유기화합물(VOC), 일산화탄소(CO), 아황산가스(SO2), 이산화질소(NO2), 소음 데이터를 수집하였다. 수집된 센서 값들은 에이전트와 oneM2M IPE를 통해 oneM2M이 제공해주는 공통 API를 활용하여 관리하였고, AE, container 등 4가지 리소스 타입으로 설계하였다. 미세먼지 측정 플랫폼 설계를 통해 동작성, 유연성, 편의성, 안전성, 개방성, 확장성의 6가지 기능을 해석하였다.

• 현장농수산연구지
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• 제22권1호
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• pp.79-85
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• 2020

이 연구는 최초의 국내 말에서 수동면역부전을 다룬 것이다. 이 연구의 목적은 건강한 말과 아픈 말의 면역상태를 비교하는 것이다. 수동면역부전은 말에서 가장 흔한 면역결핍질환이다. 아픈말 22 마리와 건강한 말 18 마리를 검사키트(SNAP Foal IgG Test Kit)를 이용하여 수동면역부전을 진단하였다. 모든 성마는 정상적인 면역기능을 가지고 있었다(≥800 mg/㎗). 신생망아지는 22 마리 중 13 마리(59%; ∠800 mg/㎗)가 면역기능이 취약하였지만 치료 후 회복하여 생존하였다. 이 22 마리 중 9 마리는 면역기능이 강한 말(≥ 800 mg/㎗)로 혈중 IgG농도가 높아도 감염성 질환이 발생할 수 있다는 것을 보여준다. 폐사망아지는 모두 6 마리였고, 그중 4 마리는 감염성 질환이었다. 신생망아지 면역상태 검사를 통한 감염취약 정도의 조기진단 및 대응방안 마련으로 경주자원 활용율 제고와 보건관리 기술향상을 도모할 수 있다. 또한, 신생망아지의 감염성질환 조기 파악으로 향후 육성마의 체계적인 보건관리방안 마련에 일조할 수 있을 것으로 기대된다.

• Journal of Microbiology and Biotechnology
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• 제32권7호
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• pp.877-884
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• 2022

Probiotics are microorganisms that can benefit host health when ingested in a live state, and lactic acid bacteria are the most common type. Among fungi, Saccharomyces boulardii (SB) is the only strain known to have a probiotic function with beneficial effects on colitis; however, information on other probiotic yeast strains is limited. Therefore, this study aimed to discover yeast strains expressing intestinal anti-inflammatory activities by exhibiting probiotic properties in dextran sodium sulfate (DSS)-induced colitis mice model. Nuruk (Korean traditional fermentation starter) containing various microbial strains was used as a source for yeast strains, and S. cerevisiae 28-7 (SC28-7) strain was selected with in vitro and in vivo characteristics to enable survival in the intestines. After 14 days of pretreatment with the yeast strains, DSS was co-administered for six days to induce colitis in mice. The results revealed that the disease activity index score was lowered by SC28-7 treatment compared to the DSS group, and the colon length and weight/length ratio were recovered in a pattern similar to that of the normal group. SC28-7 administration significantly reduced the secretion of pro-inflammatory cytokines in the serum and modified the mRNA expression of inflammatory cytokines (interleukin-1β, transforming growth factor-β, and interferon-γ) and proteins involved in gut barrier functions (mucin 2, mucin 3, zonula occludens-1, and occludin) in colon tissues. These results indicate that SC28-7 attenuates DSS-induced colon damage and inflammation, supporting its future use as a probiotic yeast for treating and preventing intestinal inflammatory diseases such as inflammatory bowel disease.

• 한국산학기술학회논문지
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• 제20권9호
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• pp.82-92
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• 2019

본 연구의 목적은 한국형도형심리 성격검사 GEOPIA(Geometry Psychological Assessment) 6가지유형과 MBTI(Myers-Briggs Type Indicator)성격유형검사 4가지 기능에 대한 연관성 및 일치정도를 분석해보고 각각의 검사도구에서 공통적으로 추천되는 적합한 수준의 직업적성을 탐구해 보는 것이다. 전국에 거주하는 19세 이상 70세 미만의 성인 남녀 377명을 대상으로 GEOPIA와 MBTI검사를 동시에 실시하였다. 측정도구의 타당도와 신뢰도검증을 위해 신뢰도(Cronbach's ${\alpha}$)값을 산출하였고 각 변수들 간의 평균과 표준편차를 구하였다. 또한 GEOPIA 검사와 MBTI 4기능 간의 관계를 알아보기 위하여 교차분석을 실시하였다. 연구결과를 살펴보면, GEOPIA 성격유형 중 동그라미세모(RT)형, 동그라미네모(RB)형, 세모네모(TB)형, 네모에스(BC)형은 MBTI의 감각/사고(ST)와 관련이 높게 나타났다. 동그라미에스(RC)형은 직관/감정(NF), 감각/감정(SF)순으로 나타났으며, 세모에스(TC)형은 직관/사고(NT)형과 관련이 높게 나타났다. 이러한 연구결과를 바탕으로 두 가지 검사의 공통적인 특성에 따라 적합한 수준의 직업적성을 제언하였다. 본 연구를 통하여 한국형도형심리 성격검사 GEOPIA가 상담이나 코칭, 교육현장에서 유용하게 사용될 수 있으며, 무엇보다 진로적성탐색을 위한 직업심리검사에 있어서도 신뢰할만한 검사도구로 유용하게 활용될 수 있음을 확인할 수 있었다.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제22권4호
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• pp.7-17
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• 2016

Purpose: As our population ages and becomes an elderly society the number of elderly care hospitals is rapidly increasing. Because physical functions and spatial perception in the elderly decrease with age, these hospitals require more systematic and intelligent space designs. The design of these spaces are even more complex because they must accommodate medical programs to treat various different diseases and ailments and also because there are many first time patients and irregular short term patients that seek out outpatient treatment services. Also by analyzing the spatial configuration systems and systematic relationships between each of the functional spaces of the outpatient treatment service departments for hospitals specialized in care for the elderly by focusing on the hallway and corridor systems of these hospitals, the according characteristics and trends were examined. Methods: Based on preceding research, the types of hallway and corridor systems of these hospitals were categorized into five types, including gallery corridors, middle corridors, hall-type, mixed type and cyclic type corridors, and into six types according to function including by medical diagnosis, patient registration, examination, administration and convenience and shared common space to derive any interconnecting relationships between the corridor systems. Also by comprehensively examining the types and combined utilization of the corridor types and the integration and the intelligibility of the space syntax, any trends within the corridor system were derived. The elderly care hospitals examined in this research study were twelve hospitals that opened after the year 2000 in Korea with more that 150 sick beds with areas larger than $1000m^2$ and with all outpatient medical service related rooms located entirely on a single floor of the hospital. Results: The following results could be confirmed based on this research study. 1) The spaces where medical diagnosis and examination occurred were adjacent, and the movement lines for first time patients and re-visiting patients were taken into consideration by separating the treatment space. 2) This research study confirmed that the larger the size of the hospital was, there were more detailed categorizations of treatment services and that there was a tendency for treatment areas to be separated and independent from examination areas. 3) There was a tendency for integration and intelligibility to decrease the more complex and diverse the combination of hall types designed into the corridor systems of these hospitals was. cyclic type corridors dramatically decreased the intelligibility of the corridor systems of these hospitals. 4) The priority rank of these spaces were confirmed to be highest in the order of registration, diagnosis, examination, treatment, administration and shared common spaces. However it was confirmed for the local integration that the diagnosis scope had the highest priority rank. Implications: There were exceptional cases confirmed where the number of unit spaces did not have an absolute effect on integration and intelligibility. These results can be interpreted to mean that this can be overcome through efficient architectural planning.

• 한국조경학회지
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• 제44권3호
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• pp.13-24
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• 2016

열악한 도시환경에서 주민이 일상적으로 가꾸어온 정원은 과연 어떤 기능과 역할을 하고 있을까? 본 연구는 일상적 도시정원을 살핌으로써, 지속가능한 도시재생의 대안을 찾고자 하였다. 이를 위해 최근 도시재생사업이 활발히 진행되고 있는 수진2동을 대상으로, 정원 조성 유형, 특성과 기능을 살펴보았다. 연구는 현장조사를 중심으로 진행하였고, 일부 조성 이유와 목적을 파악하기 위하여 인터뷰를 진행하였다. 연구 결과, 수진2동의 도시정원은 협소한 공간문제를 극복하기 위하여, 평지형보다는 입체형 정원이 주로 나타났다. 정원 조성 위치에 따라 6가지(건물 앞, 옥상, 현관지붕, 계단, 벽면, 마당)로 구분되었으며, 이중 공간 확보가 용이한 옥상 정원이 가장 많았고, 주로 생산을 목적으로 조성되었다. 지역 내 건축적 특징으로 인해 계단 정원이 상대적으로 많이 나타났는데, 주로 심미적 목적을 위해 조성되었다. 건물 앞 정원은 입구성, 시선차폐, 불법주차방지 등 다기능으로 사용하였다. 그 외, 단독주택에서는 적극적으로 조성한 수준 높은 정원이 확인되었고, 반면 다가구 주택에서는 공간이 상대적으로 협소해지며, 계단정원이 감소하고 벽면녹화가 증가하였다. 본 연구는 수진2동 도시정원의 현황과 특성을 파악함으로써, 현재 진행하고 있는 성남시 도시재생사업에서 철거와 신축만이 아니라 그 속에 살아가고 있는 주민의 삶 속에 담겨진 지혜를 발견하여 이용하는 것 또한 중요함을 말하고자 하였다. 특히 도시 공간 내에서 정원을 가꾼다는 것은 단지 개인의 취미를 넘어 도시의 공공성과 사회적 가치를 창출하고 있음을 드러내고자 하였다. 본 연구는 향후 도시재생 사업과 일상적 도시정원에 대한 이해를 위한 기초 연구로서 도움이 될 수 있을 것이라 예상한다.

• 경영과정보연구
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• 제12권
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• pp.137-160
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• 2003

The association between accounting earnings and the stock price of an entity is the subject that has been most heavily researched during the past 25 years in accounting literature. Researcher's common finding is that there are positive relationships between accounting earnings and stock prices. However, the explanatory power of accounting earnings which was measured by $R^2$ of regression functions used was rather low. To be connected with these low results, The prior studies propose that there will be additional information, errors in variables. This study investigates empirically determinants of earnings response coefficients(ERCs), which measure the correlation between earnings and stock prices, using earnings level / change, as the dependent variable in the return/earnings regression. Specifically, the thesis tests whether the factors such as earnings persistence, growth, systematic risk, image, information asymmetry and firm size. specially, the determinable variables of ERC are explained in detail. The image / information asymmetry variables are selected to be connected with additional information stand point, The debt / growth variables are selected to be connected with errors in variables. In this study, The sample of firms, listed in Korean Stock Exchange was drawn from the KIS-DATA and was required to meet the following criteria: (1) Annual accounting earnings were available over the 1986-1999 period on the KIS-FAS to allow computation of variables parameter; (2) sufficient return data for estimation of market model parameters were available on the KIS-SMAT month returns: (3) each firm had a fiscal year ending in December throughout the study period. Implementation of these criteria yielded a sample of 1,141 firm-year observation over the 10-year(1990-1999) period. A conventional regression specification would use stock returns(abnormal returns) as a dependent variable and accounting earnings(unexpected earnings) changes interacted with other factors as independent variables. In this study, I examined the relation between other factors and the RRC by using reverse regression. For an empirical test, eight hypotheses(including six lower-hypotheses) were tested. The results of the performed empirical analysis can be summarized as follows; The first, The relationship between persistence of earnings and ERC have significance of each by itself, this result accord with one of the prior studies. The second, The relationship between growth and ERC have not significance. The third, The relationship between image and ERC have significance of each by itself, but a forecast code doesn't present. This fact shows that image cost does not effect on market management share, is used to prevent market occupancy decrease. The fourth, The relationship between information asymmetry variable and ERC have significance of each by. The fifth, The relationship between systematic risk$(\beta)$ and ERC have not significance. The sixth, The relationship between debt ratio and ERC have significance of each by itself, but a forecast code doesn't present. This fact is judged that it is due to the effect of financial leverage effect and a tendency of interest.

• 동의생리병리학회지
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• 제23권4호
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• pp.805-817
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• 2009

This study was to investigate central localization of neurons projecting to the urinary bladder and urinary bladder-related acupoints(Wijung, $BL_{40}$) and neurons of immunoreactive to hormones and hormone receptors regulating urinary bladder function by using peudorabies virus(PRV). In this experiment, Bartha's strain of pseudorabies virus was used in rats to trace central localization of urinary bladder-related neurons and urinary bladder-related acupoints($BL_{40}$) which can regulate urinary system. PRV was injected into the urinary bladder and acupoints($BL_{40}$) related urinary system. After six days survival of rats, mainly common labeled neurons projecting to the urinary bladder and urinary bladder-related acupoints were identified in spinal cord, medulla, pons and diencephalon by PRV immunohistochemical staining method. First-order PRV labeled neurons projecting to urinary bladder and urinary bladder-related acupoints were found in the cervical, thoracic, lumbar and sacral spinal cord. Commonly labeled preganglionic neurons were labeled in the lumbosacral spinal cord and thoracic spinal cord. They were found in the lateral horn area(sacral parasympathetic nucleus and intermediolateral nucleus), lamina V-X, intermediomedial nucleus and dorsal column area. The area of sensory neurons projecting to urinary bladder and Wijung($BL_{40}$) was L5-S2 spinal ganglia and T12-L1 spinal ganglia, respectively. In the brainstem, the neurons were labeled most evidently and consistently in the nucleus of tractus solitarius, area postrema, dorsal motor nucleus of vagus nerve, reticular nucleus, raphe nuclei(obscurus, magnus and pallidus), C3 adrenalin cells, parapyramidal area(lateral paragigantocellular nucleus), locus coeruleus, subcoeruleus nucleus, A5 cell group, Barrington's nucleus and periaqueductal gray matter. In the diencephalon, PRV labeled neurons were marked mostly in the paraventricular nucleus and a few ones were in the lateral hypothalamic nucleus, posterior hypothalamic nucleus, ventromedial hypothalamic nucleus, arcuate nucleus, median eminence, perifornical nucleus, periventricular nucleus and suprachiasmatic nucleus. In cerebral cortex, PRV labeled neurons were marked mostly in the frontal cortex, 1,2 area, hind limb area, agranular insular cortex. Immunoreactive neurons to Corticotropin releasiing factor(CRF), Corticotropin releasiing factor-receptor(CRF-R), c-fos and serotonin were a part of labeled areas among the virus-labeled neurons of urinary bladder and Wijung($BL_{40}$). The commonly labeled areas were nucleus tractus solitarius, area postrema, reticular nucleus, raphe nuclei(obscurus, magnus and pallidus), locus coeruleus, A5 cell group, Barrington,s nucleus, arcuate nucleus, paraventricular nucleus, frontal cortex 1, 2 area, hind limb, and perirhinal(agranular insular) cortex. These results suggest that overlapped CNS locations are related with autonomic nuclei which regulate the functions of urinary bladder-relate organs and it was revealed by tracing PRV labeled neurons projecting urinary bladder and urinary bladder-related acupoints. These commonly labeled areas often overlap with the neurons connected with hormones and hormone receptors related to urination.

• 대한한의학회지
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• 제19권2호
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• pp.373-390
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• 1998

35 theses conducted in Korea on the topic of senescence or anti-oxidant were classified on the basis of research methods, animals used for the experiments, and research items. Evaluating these research works with respect to the Free Radical Theory, the following conclusions were reached. 1. Of the 17 theses written in the Oriental medicine aspect, three theses used a single herb, nine theses used a complex prescription, four theses concentrated on the usage of the medicinal acupuncture, and one research paper focused on using scientific components. Common objection of these papers were on the verification of the efficacy of herbs. 2. Of the 18 these written in the Western medicine aspect, five theses used a single drug, seven theses conducted a research on the changes due to senescence, and 6 papers were on variety of topics. The main focus of these works were on the mechanism and pathology related to the senescence rather than on the suppression of senescence. 3. Among the theses written in the Oriental medicine perspective, a total of 48 herbs were utilized. 26 of these herbs has a tonification function on the Kidney. Six out of nine complex prescription mentioned above has a function of tonifying the Kidney. 4. With respect to the research subjects used on the experiments, 8 theses have used Senescence-Accelerated mice, 13 theses have used Sprague-Dawley mice, and remaining 7 papers have used human or other animals. 5. These are the categorization of the research items used: the weight (11) and weight changes of the visceral organs (9), the measurement of the content of peroxide-disease (9), the measurement of enzyme vitality (21), the blood and urine test (10), the experiment concerning immune system (3), the influence on the hepatic capability of metabolizing foreign substance (3), the effect on hepatic cell protection (3), the measurement of both the suppression of Free Radical and ability to create Free Radical (2), the measurement of effect of suppresing MDA(malondialdehyde) (4), the effect of eliminating DPPH Radical (2), and experiements about the functions (2). 6. The rate of vitalization of well known anti-oxidants such as Superoxide dismutase (SOD), Protein-bound SH, Nonprotein-bound SH, Glutathione(GSH), Catalase, and etc. were tested in 17 theses. Considering the conclusions mentioned above, the theses related to the senescence published in Korea elected different animals used for experiments, research items and the methods of research, the end result seems to be a lack of objectivity. Thus, I would argue that research methods to overcome such a deficiency need to be developed systematically.

• 한국가정과교육학회지
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• 제20권2호
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• pp.15-30
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• 2008

본 연구는 가정교과가 학습자의 흥미와 관심에 부합하여 실생활에 활용 가능한 학습자 중심의 실천교과가 되도록 옷차림 영역을 중심으로 활동과제 개선을 위한 기초 자료를 제공하고자 하였다. 이를 위해, 7차 교육과정의 중학교 2학년 기술 가정 10종 교과서에 수록되어 있는 의생활 단원의 활동과제를 분석하였다. 활동과제는 활동과제 수행 시 '집단의 규모', '문제의 유형', '과제 수행 방법'에 따라 분류하여 분석하여 활동과제의 내용 구성, 수행방법, 제시방법 등 활동과제가 나아가야 할 방향을 모색해 보았으며 연구결과는 다음과 같다. 첫째, 중학교 2학년 기술 가정 교과 의생활 영역의 옷차림 단원의 비율을 살펴본 결과 의생활 단원의 5개 단원 중 가장 높은 비율을 차지하고 있었으며, 옷차림 단원의 6가지 세부 내용 중 '한복의 종류와 바르게 입는 방법'과 '의복의 기능의 복의 종류와 특징'이 가장 많은 비율을 차지하고 있었다. 둘째, 활동과제의 문제의 유형과 과제 수행 방법은 출판사와 옷차림 영역 세부내용 간에 차이를 보였으나 집단의 규모는 '개별활동', 문제의 유형은 '구조화된 문제', 과제 수행방법은 '가정에서 이전 경험으로부터 해결할 수 있는 과제'가 가장 많은 비중을 차지하고 있었다. 따라서 가정교과가 학습자 중심의 실천교과가 되기 위해 활동과제의 내용은 학생의 요구, 교육현장의 여건 등을 고려하며 학생들의 일상생활에 중심을 두고, 소집단 활동의 비율을 높이는 것이 바람직하다. 또한 활동과제는 구조화되지 않은 문제와 같이 다양하고 포괄적인 문제 상황을 제시하는 것이 학생의 창의력, 사고력을 신장시키는데 도움이 될 것이며, 수행 방법을 다양하게 구성할 필요가 있다.