• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3035-3041
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• 2016

Breast cancer (BC) is the most common malignancy of women worldwide. In the past it was considered as disease of older middle aged women, but the incidence of BC in young females is growing in recent years concordant with studies in Pakistan. In this paper, we reviewed the mutant functions of tumor suppressor genes (BRCA1, BRCA2, p53, ATM and PTEN), epigenetic transformation and involvement of estrogen receptors in development of breast cancer. We further reviewed the current situation of BC in Pakistan that depicts a higher incidence in young females. According to SKMCH and RC data, age group 45-49 years is more prone to BC with high rate of incidence 45.42%. A few studies explored the high expression of ER, PR and HER-2/neu in Pakistani females. Moreover, presence of BRCA1 (c.1961dupA) mutation in Pakistani shows concordance with data in different areas of world. But we are unable to find an authentic study that can explore epigenetic based transformation of breast tumors in Pakistan. This area of research needs more attention to explore the complete picture of BC in Pakistan.

• Education of Primary School Mathematics
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• v.5 no.2
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• pp.71-94
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• 2001

The purposes of this study were to design small group collaborative learning models for developing the creativity and to analyze the effects on applying the models in mathematics teaching and loaming. The meaning of open education in mathematics learning, the relation of creativity and inquiry learning, the relation of small group collaborative learning and creativity, and the relation of assessment and creativity were reviewed. And to investigate the relation small group collaborative learning and creativity, we developed three types of small group collaborative learning model- inquiry model, situation model, tradition model, and then conducted in elementary school and middle school. As a conclusion, this study suggested; (1) Small group collaborative learning can be conducted when the teacher understands the small group collaborative learning practice in the mathematics classroom and have desirable belief about mathematics instruction. (2) Students' mathematical anxiety can be reduced and students' involvement in mathematics learning can be facilitated, when mathematical tasks are provided through inquiry model and situation model. (3) Students' mathematical creativity can be enhanced when the teacher make classroom culture that students' thinking is valued and teacher's authority is reduced. (4) To develop students' mathematical creativity, the interaction between students in small group should be encouraged, and assessment of creativity development should be conduced systematically and continuously.

• Archives of design research
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• v.17 no.4
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• pp.259-268
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• 2004

Today is so-called brand war age. Brand equity has been a critical factor to evaluate the business value according to changes of competitive situation and consumer's choices under the 21 century market situation. Brand advertisement with character on TV commercial has long been common and effective ways for many years as useful methods of brand differentiation in the consumer mind. In this thesis, character's roles and possibilities are researched to enhance a brand awareness in marketing, and also the interrelation between the patterns of character and the involvement on TV commercials over several categories are analyzed through the grid model of FCB that is a advertising agency in U.S.A. The attitude of Character usage and technique are also examined by analyzing the materials and the expressive methods of characters in each category.

• Journal of Radiation Protection and Research
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• v.48 no.3
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• pp.107-116
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• 2023

This article reviews the experience of applying the Identification, Diagnosis, Prospective, and Action (IDPA) facilitating method as a means of promoting practices of dialogue between stakeholders in the radiological protection field. After presenting the characteristics of the IDPA method and its ability to promote active listening, participation, and dialogue among stakeholders facing complex situations, as well as the procedural aspects associated with its practical implementation, the article describes three examples of the application of the method in the field of radiological protection. The first one presents how the IDPA method supported a debate among decision-makers, authorities, experts, professionals, and representatives of non-governmental organizations about how to engage stakeholders in radiological protection. The second example presents how the IDPA method was used in a series of dialogue meetings to explore the challenges of the post-nuclear accident situation resulting from the Fukushima Daiichi Nuclear Power Plant accident. The third one presents the application of the method in the context of a training course organized by Nagasaki University in the affected area close to the damaged plant. Experience has shown that the IDPA method makes it possible to develop responses to problems posed in very different contexts and, in many cases, to find compromises regarding their solutions. The IDPA method has the merit of allowing each of the participants to better understand the situation they are faced with, even if such a positive result is not always achieved.

• Journal of the Korean Institute of Intelligent Systems
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• v.17 no.7
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• pp.907-912
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• 2007

The present level of ubiquitous computing technology have developed to the point where Home-server provides services that user require directly for user in the intelligent space. But it will need intelligent system to provides more active services for user in the near future. In this paper, we define the environment information about situation that user is in as Context, and collect the Context that stereotype as 4W1H form for construct the system that can decision service will be provide from information about a situation that user is in, without user's involvement. Additionally we collect information about user's emotional state, use these informations as nodes of Bayesian network for probabilistic reasoning. From that, we materialize Context Awareness system about it that what kind of situation user is in. And, we propose the Context-based Service reasoning model using Bayesian Network from the result of Context Awareness.

• Journal of the Korean Society of Clothing and Textiles
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• v.30 no.3 s.151
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• pp.470-480
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• 2006

Consumer may perceive needs of certain product information online rather than the number of pieces of information available for decision making. In addition, consumers may seek information that is more relevant to apparel category. Moreover, involved consumers intensify information seeking and seek certain information. The purpose of this study is to identify the perceived importance weight of each information cue when shopping apparel via the Internet, to investigate the differences of the perceived importance weight of product information cues in product category, and to examine the relationship between apparel involvement and the perceived importance weight of product information cues. This study employed a single-factor within-subjects design experiment that simulated online purchase situation for two product types, Jeans and a Shirt. A total of 125 college students participated in this study. Results indicated that selected information such size available, price, style, color description, item measurement, stock available, and item quality (in sequence) can be considered as global cues to judge product quality and influence purchase decision regardless of product category. The significant multivariate effects for product category on the perceived importance weight of product information cues were found. Personalization, fiber content, and fabric structure were product specific information cues. Consumers' product involvement significantly influenced the perception of information weight. Therefore, product information can be personalized based on consumer involvement

• Journal of Families and Better Life
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• v.18 no.2
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• pp.77-91
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• 2000

The purpose of this study is twofold: to document the current research trends, significance, and actual situation of family business in Germany, and to describe the characteristics of family business work, workers, and interactions influencing work and family functioning in Germany. For this purpose, this study reviewed the sate of family business in Germany through out theoretical approach and secondary national data. In addition, this study collected in 1998 data through face-to-face interviews with female family business managers in Germany. Results of the present study indicate that family business plays a very important role in the economy of Germany. More than 85% of all companies are family businesses, which produce over 60% of GDP in Germany. The notable characteristics of family business households were the high proportion of home owners, high education level of the family business manager, high involvement of family members in family business. Also the high work sati faction among the family members who worked in family business, the effect of family business work on family life, and effect of the family on business success were extremely positive.

• Journal of muscle and joint health
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• v.10 no.2
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• pp.119-130
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• 2003

Illness intrusiveness(illness induced lifestyle disruption) was investigated in 902 patients with arthritis and compared between rheumatoid arthritis(N=439) and osteoarthritis(N=463) patients. Arthritis patients were reported to perceive illness intrusiveness similar to patients with ESRD(end stage renal disease), bipolar disorder and peritoneal dialysis. Especially they were intrusive into health, work, and active recreation domains. And patients with rheumatoid arthritis were significantly more intrusive into activities, especially in diet, financial situation, family relations, other social relations, self-expression/self improvement, religious expression, and community and civic involvement. Differences in treatment regimens and age were hypothesized to account for these differences in illness intrusiveness.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2005.11a
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• pp.82-83
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• 2005

Recently, layer industry shows the decrease in the number of farm and increase in rearing scale in both Korea and Japan. Seventy percent of layer farms in Japan feed more than 50,000 birds per each farm but in Korea, only 19.3% of layer farms are feeding more than 30,000 birds which covers 59% of total chicken number. This tendeney will be more accellerated from now on. Brand egg Production in Japan is developed with the involvement of farmers, sailers feed companies and also the marketing structure of brand egg is well organised in between farmers and consumers. However in Korea, the marketing structure of brand egg is not well settled for this reason the egg price is often decided lower much price than regrnlar price by the intermediate dealers. Under this kind of tough situation, Korean layer farmers are stressed to develop new brand products such as functional egg, settle the sales and distribution network with the good cooperation of farmers, and distributers.

• Journal of Information Technology Applications and Management
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• v.11 no.3
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• pp.89-116
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• 2004

Insurance companies are in a fierce race to catch a new customer. In this situation. sales force automation technologies are often used to support customer relationship management strategies. This study sets out a research model predicting SFA(Sales Force Automation) usage through theoretical studies. Survey data were collected from 145 salespeople across 2 firms that had implemented sales force automation tools and hypotheses were tested empirically. Data were analyzed by path-analysis method of AMOS. The major findings of this study are as follows: Computer self-efficacy, user involvement and voluntariness have a statistically significant influence on the positive perceptions of SFA. These perceptions have a statistically significant influence on user satisfaction and usage of SFA. while user satisfaction has a statistically significant influence on SFA usage. This paper concludes with the discussion of these results and their implications for academic researchers and insurance company managers.