• Journal of Radiation Industry
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• v.18 no.1
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• pp.43-52
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• 2024

Currently, there are no interim storage facilities and permanent disposal facilities in Korea, so all spent nuclear fuels are temporarily stored. However, the temporary storage facility is approaching saturation, and as a measure to this, the 2nd Basic Plan for the Management of High-Level Radioactive Waste presented an operation plan for dry interim storage facilities and dry temporary storage facilities on the NPP on-site. The dry storage can be operated in various ways, and to select the optimal dry storage method, the reduction of exposure for workers must be considered. Accordingly, it is necessary to develop a worker exposure scenario according to the dry storage method and evaluate and compare the radiological impact for each method. The purpose of this study is to develop an exposure scenario for workers transporting spent nuclear fuel by dry storage method. To this end, first, the operation procedure of the foreign commercial spent nuclear fuel dry storage system was analyzed based on the Final Safety Analysis Report (FSAR). 1) the concrete overpack-based system, 2) the metal overpack-based system, and 3) the vertical storage module-based system were selected for analysis. Factors were assumed that could affect the type of work (working distance, working hours, number of workers, etc.) during transportation work. Finally, the work type of the processes involved in transporting spent nuclear fuel by dry storage method was set, and an exposure scenario was developed accordingly. The concrete overpack method, the metal overpack method, and the vertical storage module method were classified into a total of 31, 9, and 23 processes, respectively. The work distance, work time, and number of workers for each process were set. The product of working hours and number of workers (Man-hour) was set high in the order of concrete overpack method, vertical storage module method, and metal overpack method, and short-range work (10 cm) was most often applied to the concrete overpack method. The results of this study are expected to be used as basic data for performing radiological comparisons of transport workers by dry storage method of spent nuclear fuel.

• Journal of Korea Water Resources Association
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• v.57 no.7
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• pp.461-470
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• 2024

This study aimed to predict total phosphorus (T-P) to address early eutrophication caused by nutrient influx from various human activities. Traditional T-P monitoring systems are labor-intensive and time-consuming, leading to a global trend of using direct reading sensors. Therefore, this study utilized water quality parameters obtained from direct reading sensors in a two-stage T-P prediction process. The importance of turbidity (Tur) in T-P prediction was examined, and an analysis was conducted to determine if T-P prediction is possible using only direct reading sensor parameters by adding automatic water quality analyzer parameters. The study found that T-P concentrations were higher in the mid-lower reaches of the Nakdong River basin compared to the upper reaches. Pearson correlation analysis identified water quality parameters highly correlated with T-P at each site, which were then used in multiple linear regression analysis to predict T-P. The analysis was conducted with and without the inclusion of Tur, and the performance of models incorporating automatic water quality analyzer parameters was compared with those using only direct reading sensor parameters. The results confirmed the significance of Tur in T-P prediction, suggesting that it can be used as a foundational element in the development of measures to prevent eutrophication.

• Journal of Life Science
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• v.34 no.9
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• pp.656-665
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• 2024

Enzymes, as proteins that regulate various metabolic processes within the human body, play a crucial role in maintaining health. However, the overexpression of certain enzymes can disrupt metabolic balance, leading to various diseases. Enzyme inhibitors are vital in treating these diseases or conditions by inhibiting the action of these enzymes, making them indispensable in the development of effective therapies for a wide array of diseases. Quercetin, a natural product derived from plants, is a type of flavonoid that belongs to the polyphenol family. Quercetin, a natural flavonoid from the polyphenol family, has emerged as a potent enzyme inhibitor. This low-molecular-weight secondary metabolite is known for its inhibitory effects on enzymes such as α-glucosidase, acetylcholinesterase, bacterial neuraminidase, and xanthine oxidase due to its structural advantages. Quercetin is isolated from biomaterials and can be classified into glycosylated, methoxylated, and alkylated derivatives based on its structural variations. These natural quercetin derivatives possess unique substituents that enable specific binding patterns with catalytic residues in enzyme active sites. Therefore, quercetin derivatives can be expected to have better enzyme inhibitory activity than basic quercetin. Due to their specificity and enhanced activity, quercetin and its derivatives hold promise as candidates for developing potent enzyme inhibitors to treat diseases resulting from enzyme imbalances.

• The Korean Journal of Air & Space Law and Policy
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• v.20 no.1
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• pp.9-43
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• 2005

The Korean government established her first "National Space Program" in 1996, and revised it in 2000 and 2005. As embedded in the National Space Program, Korea aims to become one of the world's top countries in space technology by 2010. All of 13 satellites are planned to be put into orbit as schematized, which include 7 multi-purpose satellites, 4 science satellites and 2 geostationary orbit satellites. The Space Center in Korea is to be built at Woinara-Do, Bongrae-Myon, Koheung-Goon, Junlanam Province on the southern coast of the Korean peninsular. The first phase of the construction of the space center will be finished by 2007 for launch of KSLV-l. This will make Korea be the 13th advanced country in space development having a launching site in the world. The "Space Center" will serve as the infrastructure for the development of space technology and related technology, and plan to launch a low earth orbit satellite in 2007. A second science satellite made in Korea will be launched from the space center by 2007. From 2010, the center will be operated on a commercial basis operating launch facilities for low-to mid-altitude orbit satellites. Since the 'Aircraft Industry Promotion Act' was replaced by the 'Aerospace Industry Development Promotion Acf of 1987, this Act had been amended seven times from 1991 year to 2004. Most of developed countries has been enacted the space law including the public or private items such as an (1)DSA, (2)Russia, (3)the United Kingdom, (4)Germany, (5)France, (6)Canada, (7)Japan, (8)Sweden, (9)Australia, (10)Brazil, (11)Norway, (12)South Africa, (13)Argentina, (14)Chile, (15)Ukrainian etc. As the new Space Exploration Promotion Act was passed by the resolution of the Korean Congress on May 3, 2005, so the Korean government has made the public proclamation the abovementioned Act on May 31, this year. This Act takes effect on December 1, 2005 after elapsing six months from the date of promulgation. The main contents of Space Exploration Promotion Act of 2005 is as the following (1)establishing a basic plan for promoting space exploration, (2)establishment and function of national space committee, (3)procedure and management of domestic and international registration of space objects, (4)licensing of launch by space launch vehicles, (5)lability for damages caused by space accidents and liability insurance, (6) organizing and composition of the space accident investigation committee, (7)Support of non-governmental space exploration project, (8)Requesting Support and Cooperation of Space Exploration, (9)Rescue of Astronauts and Restitution of Space Objects, etc.. In oder to carry out successfully the medium and long basic plan for promoting space exploration and to develope space industry in Korea, I think that it is necessary for us to enlarge and to reorganize the function and manpower of the Space Technology Development Division of the Ministry of Science & Technology and the Korea Aerospace Research Institute. Korea has been carrying out its space program step by step according to the National Space Program. Korea also will continually strengthen the exchange and cooperation with all the countries in the world under the principle of equality, friendship relations and mutual benefits. Together with all other peoples around the globe, Korea will make due contribution towards the peaceful utilization of space resources and promotion of human progress and prosperity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.1-24
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• 2003

This study was done to compile 104 experimental theses which are related to the antitumor and immuno-activating therapies between February 1990 through February 2002. Master's and doctoral theses were dassified by schools, degrees, materials, effects, experimental methods of antitumor and immunoactivity, and results. The following results were obtained from this study : 1. Classifying the theses by the school, 34.6% were presented by Daejeon University, 29.8% by Kyung-hee University and 11.5% by Won-kwang University. Of all theses, 51.0% were aimed for the doctoral degree and 43.3% were for the master's degree. All of three universities have their own cancer centers. 2. Classifying the theses by herb materials, complex prescription accounted for 60.3%, single herb accounted for 24.8% and herbal acupuncture accounted for 14.2%. Considering the key principles of the traditional medicine, complex prescription was much more thoroughly studied than single herb prescription. The results showed that the complex prescription had both antitumor activity and immuno-activating activity, which might reflects on multi-activation mechanisms by complex components. 3. Classifying the theses by the efficacy of herbs examined, in single herb, invigorating spleen and supplementing was 35.5%, expelling toxin and cooling was 29.0%, activating blood flow and removing blood stasis was 12.9%. In herbal acupuncture, invigorating spleen and supplementing was 52.9%, expelling toxin and cooling was 29.4%. In complex prescription, pathogen-free status was 41.9%, strengthening healthy qi to eliminate pathogen was 35.5%, strengthening healthy qi was 22.6%. It is presumed that the antitumor and immunoactivating therapy based on syndrome differentiation is the best way to develop oriental oncology. 4. Classifying the theses by antitumor experiments, cytotoxic effect was 48.1 %, survival time was 48.1 % and change of tumor size was 42.3%. Survival rate was not necessarily correlated with cytotoxicity. These data reflect the characteristic, wholistic nature of the oriental medicine which is based on BRM (biological response modifier). 5. Classifying the theses by immunoactivating experiments, hemolysin titer was 51.0%, hemagglutinin titer was 46.2% and NK cell's activity was 44.2%. In the future studies, an effort to elucidate specific molecular and cellular mechanisms of cytokine production in the body would be crucial. 6. Classifying the theses according to the data in terms of antitumor activity, 50% was evaluated good, 24.0% was excellent, and 15.5% have no effect. In an evaluation of immuno-activating activity, 35.9% was excellent and 18.0% showed a little effect. The index point, as described here, may helps to use experimental data for clinical trials. Changes in index points by varying dosage implicate the importance of oriental medical theory for prescription. 7. In 167 materials, IIP (immunoactivating index point, mean : 3.12±0.07) was significantly higher than AIP(antitumor index point, mean : 2.83±0.07). These data demonstrate that the effect of herb medicine on tumor activity depends more on immunoactivating activity than antitumor activity. This further implies that the development of herbal antitumor drugs must be preceded by the mechanistic understanding of immunoactivating effect. 8. After medline-searching tumor and herb-related articles from NCBI web site, we conclude that most of the studies are primarily focused on biomolecular mechanisms and/or pathways. Henceforth, we need to define the biomolecular mechanisms and/or pathways affected by herbs or complicated prescriptions. 9. Therefore, the most important point of oriental medical oncology is to conned between experimental results and clinical trials. For the public application of herbal therapy to cancer, it is critical to present the data to mass media. 10. To develop the relationship of experimental results and clinical trials, university's cancer clinic must have a long-range plan related to the university laboratories and, at the same time, a regular consortium for this relationship is imperative. 11. After all these efforts, a new type herbal medicine for cancer therapy which is to take care of the long-term administering and safety problem must be developed. Then, it would be expected that anti-tumor herbal acupuncture can improve clinical symptoms and quality of life (QOL) for cancer patients. 12. Finally, oriental medical cancer center must be constructed in NCC (National Cancer Center) or government agency for the development of oriental medical oncology which has international competitive power.

• Korean Journal of Environment and Ecology
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• v.31 no.4
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• pp.409-419
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• 2017

Although Korean red pine (Pinus densiflora) forests near temples are valuable as forests of the cultural landscape, they are likely to be deteriorated because of vegetation succession and climate changes. The purpose of this study is to investigate the vegetation structure, the pine vitality, and the site environmental characteristics of the pine forests near temples to identify the correlation between pine tree growth and location environment. We selected Chuneunsa, Wonhyosa, Jeungsimsa, and Taeansa Temples since these four areas still had the healthy pine forests. In all four studied area, the pine trees dominate the canopy layers while the deciduous broadleaf trees mostly inhabited appeared in the lower layers. The growth of pine trees in Jeungsimsa and Wonhyosa areas was not as good as Chuneunsa area where the pine trees tended to be older. We found higher total nitrogen content in soil in Jeungsimsa area than other areas, maybe because of increase in total nitrogen caused by the development of low vegetation in the area. This peculiarity may have led to the pine trees in the area to fall behind the deciduous broadleaf trees in competition for nitrogen nutrient and thus to show deteriorated growth. The altitude and the twig length showed a negative correlation as did the degree of slope and the mean importance percentage of the pine tree. In other words, the growth environment such as soil became poorer when the altitude and the degree of slope increased, and thus the growth amount and dominance of the pine trees were lower. The degree of slope showed a positive correlation with the twig length of the pine tree. Within boundaries of location environment where the pine tree forests were dominant, it seemed that growth of the pine trees was more favorable as the slope was steeper because the trees could avoid competition with deciduous broadleaf trees. On the other hand, the growth of pine trees deteriorated as the electrical conductivity of soil increased; increase in soil nutrients might have accelerated vegetation development of deciduous broadleaf trees and thus aggravated the growth environment of pine trees to negatively affect maintaining the health of the pine tree forests.

• Korean Journal of Agricultural and Forest Meteorology
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• v.22 no.1
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• pp.26-46
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• 2020

An irrigated-maize agroecosystem is viewed as an open thermodynamic system upon which solar radiation impresses a large gradient that moves the system away from equilibrium. Following the imperative of the second law of thermodynamics, such agroecosystem resists and reduces the externally applied gradient by using all means of this nature-human coupled system acting together as a nonequilibrium dissipative process. The ultimate purpose of our study is to test this hypothesis by examining the energetics of agroecosystem growth and development. As a first step toward this test, we employed the eddy covariance flux data from 2003 to 2014 at the AmeriFlux NE1 irrigated-maize site at Mead, Nebraska, USA, and analyzed the energetics of this agroecosystem by scrutinizing its radiation, energy and entropy exchange. Our results showed: (1) more energy capture during growing season than non-growing season, and increasing energy capture through growing season until senescence; (2) more energy flow activity within and through the system, providing greater potential for degradation; (3) higher efficiency in terms of carbon uptake and water use through growing season until senescence; and (4) the resulting energy degradation occurred at the expense of increasing net entropy accumulation within the system as well as net entropy transfer out to the surrounding environment. Under the drought conditions in 2012, the increased entropy production within the system was accompanied by the enhanced entropy transfer out of the system, resulting in insignificant net entropy change. Drought mitigation with more frequent irrigation shifted the main route of entropy transfer from sensible to latent heat fluxes, yielding the production and carbon uptake exceeding the 12-year mean values at the cost of less efficient use of water and light.

• Korean Journal of Remote Sensing
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• v.33 no.5_2
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• pp.661-676
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• 2017

This study suggests a new method not only to produce the 1 km-resolution seasonal prediction but also to improve the seasonal prediction skill of temperature over South Korea. This method consists of four stages of experiments. The first stage, EXP1, is a low-resolution seasonal prediction of temperature obtained from Pusan National University Coupled General Circulation Model, and EXP2 is to produce 1 km-resolution seasonal prediction of temperature over South Korea by applying statistical downscaling to the results of EXP1. EXP3 is a seasonal prediction which considers the effect of temperature changes according to the altitude on the result of EXP2. Here, we use altitude information from ASTER GDEM, satellite observation. EXP4 is a bias corrected seasonal prediction using genetic algorithm in EXP3. EXP1 and EXP2 show poorer prediction skill than other experiments because the topographical characteristic of South Korea is not considered at all. Especially, the prediction skills of two experiments are lower at the high altitude observation site. On the other hand, EXP3 and EXP4 applying the high resolution elevation data based on remote sensing have higher prediction skill than other experiments by effectively reflecting the topographical characteristics such as temperature decrease as altitude increases. In addition, EXP4 reduced the systematic bias of seasonal prediction using genetic algorithm shows the superior performance for temporal variability such as temporal correlation, normalized standard deviation, hit rate and false alarm rate. It means that the method proposed in this study can produces high-resolution and high-quality seasonal prediction effectively.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.33 no.4
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• pp.140-147
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• 2015

The garden culture of Korea and Japan have been commonly influenced by Wonrim culture of China. Nevertheless, each culture has been settled down through the development of the two separate garden cultures, The purpose of this study is to grasp the formation background and main agent of development through theoretical consideration of gardens in Japanese Imperial Garden Katsura Imperial Villa, which is the origin of the representative garden making style-Circuit Style Garden, to look into the characteristic of spatial organization elements by conducting on-site survey and interview with a garden manager, and to obtain elementary views on Katsura Imperial Villa which is an important case of Japanese garden culture. As a result; first, Katsura Imperial Villa is the first jicheol juyu(round tour of ponds and springs) circuit style garden created by Toshihito Emperor and his son Toshitada Emperor, who were well-versed in Waka through the dynasty literature based on the story of Genji throughout about two generations lasting about 30 years; space composition of this garden is divided into land, island and water space, being composed of a total of 36 space components. Second, Katsura Imperial Villa was created with the primary goal of making a round tour around the garden land by arranging tea pavilions, such as Shokintei, Shokatei and Shoiken, etc., which introduced the then game culture into the garden. Third, the personnel in Katsura Imperial Villa intended to enjoy the scenic characteristics of the area where Katsura Imperial Villa was located from the interior of the garden by making Gepparo which was a tea pavilion for enjoying the rising moon on the hill even a litter faster and longer by piling up earth and setting up stone walls north of Koshoin which was a structure located west of the garden land.

• Journal of Intelligence and Information Systems
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• v.21 no.4
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• pp.93-110
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• 2015

The recommender system is a system which recommends products to the customers who are likely to be interested in. Based on automated information filtering technology, various recommender systems have been developed. Collaborative filtering (CF), one of the most successful recommendation algorithms, has been applied in a number of different domains such as recommending Web pages, books, movies, music and products. But, it has been known that CF has a critical shortcoming. CF finds neighbors whose preferences are like those of the target customer and recommends products those customers have most liked. Thus, CF works properly only when there's a sufficient number of ratings on common product from customers. When there's a shortage of customer ratings, CF makes the formation of a neighborhood inaccurate, thereby resulting in poor recommendations. To improve the performance of CF based recommender systems, most of the related studies have been focused on the development of novel algorithms under the assumption of using a single profile, which is created from user's rating information for items, purchase transactions, or Web access logs. With the advent of big data, companies got to collect more data and to use a variety of information with big size. So, many companies recognize it very importantly to utilize big data because it makes companies to improve their competitiveness and to create new value. In particular, on the rise is the issue of utilizing personal big data in the recommender system. It is why personal big data facilitate more accurate identification of the preferences or behaviors of users. The proposed recommendation methodology is as follows: First, multimodal user profiles are created from personal big data in order to grasp the preferences and behavior of users from various viewpoints. We derive five user profiles based on the personal information such as rating, site preference, demographic, Internet usage, and topic in text. Next, the similarity between users is calculated based on the profiles and then neighbors of users are found from the results. One of three ensemble approaches is applied to calculate the similarity. Each ensemble approach uses the similarity of combined profile, the average similarity of each profile, and the weighted average similarity of each profile, respectively. Finally, the products that people among the neighborhood prefer most to are recommended to the target users. For the experiments, we used the demographic data and a very large volume of Web log transaction for 5,000 panel users of a company that is specialized to analyzing ranks of Web sites. R and SAS E-miner was used to implement the proposed recommender system and to conduct the topic analysis using the keyword search, respectively. To evaluate the recommendation performance, we used 60% of data for training and 40% of data for test. The 5-fold cross validation was also conducted to enhance the reliability of our experiments. A widely used combination metric called F1 metric that gives equal weight to both recall and precision was employed for our evaluation. As the results of evaluation, the proposed methodology achieved the significant improvement over the single profile based CF algorithm. In particular, the ensemble approach using weighted average similarity shows the highest performance. That is, the rate of improvement in F1 is 16.9 percent for the ensemble approach using weighted average similarity and 8.1 percent for the ensemble approach using average similarity of each profile. From these results, we conclude that the multimodal profile ensemble approach is a viable solution to the problems encountered when there's a shortage of customer ratings. This study has significance in suggesting what kind of information could we use to create profile in the environment of big data and how could we combine and utilize them effectively. However, our methodology should be further studied to consider for its real-world application. We need to compare the differences in recommendation accuracy by applying the proposed method to different recommendation algorithms and then to identify which combination of them would show the best performance.