• Journal of Industrial Technology
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• v.12
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• pp.25-36
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• 1992

In this paper, we simulate and calculate the stress and output voltage of the beam structure load cells by using FEM as varing physical structure parameters and loading positions. It is proved that stress enhance as the increase of the notch pitch and radius of the load cell, but decrease as the increase of the notch thickness and beam width. The results are good matched for basic formulas of the single fixed beam, and are verified our simulation is correct. Also, it is found that the stress characteristics of the load cell is varied according to loading positions with structure parameters, and caculated output voltage of the load cell approximate to those of the real manufactured ones. As a result, this study will offer efficient design and analysis technique for making special and variety capacity of load cells.

• International Journal of Aeronautical and Space Sciences
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• v.4 no.1
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• pp.9-18
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• 2003

In this work, a closed-form analysis is performed for the structural response of coupled composite blades with multi-cell sections. The analytical model includes the effects of shell wall thickness, transverse shear, torsion warping and constrained warping. The mixed beam approach based on Reissner's semi-complementary energy functional is used to derive the beam force-displacement relations. The theory is validated against experimental test data and other analytical results for coupled composite beams and blades with single-cell box-sections and two-cell airfoils. Correlation of the present method with experimental results and detailed finite element results is found to be very good.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.26 no.4
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• pp.31-41
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• 2003

This paper deals with a cell formation problem for a set of m-machines and n-processing parts. Generally, a cell formation problem is known as NP-completeness. Hence the cell formation problem with multiple objectives is more difficult than single objective problem. The paper considers multiple objectives; minimize number of intercell movements, minimize intracell workload variation and minimize intercell workload variation. We propose a multiple objective genetic algorithms(MOGA) resolving the mentioned three objectives. The MOGA procedure adopted Pareto optimal solution for selection method for next generation and the concept of Euclidean distance from the ideal and negative ideal solution for fitness test of a individual. As we consider several weights, decision maker will be reflected his consideration by adjusting high weights for important objective. A numerical example is given for a comparative analysis with the results of other research.

• Journal of information and communication convergence engineering
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• v.4 no.1
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• pp.36-40
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• 2006

A new method of digital image analysis technique for medical images of cancer cell is presented. This paper deals with the cancer cell discrimination. The object images were the Thyroid Gland cell images that were diagnosed as normal and abnormal. This paper proposes a new discrimination method based on fuzzy logic algorithm. The focus of this paper is an automatic discrimination of cells into normal and abnormal of medical images by dominant feature parameters method with fuzzy algorithm. As a consequence of using fuzzy logic algorithm, the nucleus were successfully diagnosed as normal and abnormal. As for the experimental result, average recognition rate of 64.66% was obtained by applying single parameter of 16 feature parameters at a time. The discrimination rate of 93.08% was obtained by proposed method.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.1
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• pp.39-45
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• 2015

We investigated whether multiple infections can be used as predictors of progression to carcinogenesis in accordance with the cytological diagnosis in women receiving abnormal cytologic diagnosis as analysis genotype and compared to single infection. HPV prevalence is highest in the age of under 30 years old woman, HPV prevalence is started to lower after 30 years old and started to increase over 60 years old as like a U-shape. The specific HPV genotypes is an important factor because increased single infection and reduced multiple infections and appeared single infection with AC in progressing carcinogenesis. HPV 16 revealed the statistical significance at the single infection in squamous cell lesions, and HPV 18 revealed the statistical significance at the single infection in adenocarcinoma with showed HPV 16, 58, 18, 52-type distribution.

• Journal of the Korean Electrochemical Society
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• v.12 no.1
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• pp.61-67
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• 2009

Flow-field design has much influence over the performance of proton exchange membrane fuel cell (PEMFC) because it affects the pressure magnitude and distribution of the reactant gases. To obtain the pressure magnitude and distribution of reactant gases in five kinds of flow-field designs, computational fluid dynamics (CFD) analysis was performed. After the CFD analysis, a single cell test was carried out to obtain the performance values. As expected, the pressure differences due to different flow-field configurations were related to the PEMFC performance because the actual performance results showed the same tendency as the results of the CFD analysis. A large pressure drop resulted in high PEMFC performance. The single serpentine configuration gave the highest performance because of the high pressure difference magnitudes of the inlet/outlet. On the other hand, the parallel flow-field configuration gave the lowest performance because the pressure difference between inlet and outlet was the lowest.

• Biotechnology and Bioprocess Engineering:BBE
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• v.6 no.2
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• pp.117-127
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• 2001

The high-level expression of a human single chain urokinase-type plasminogen activator (scu-PA) was achieved by employing a methotrexate (MTX)-dependent gene amplification system in Chinese hamster ovary (CHO) cells. By cotransfecting and coamplifying a scu-PA expression plasmid and dihydrofolate reductase (DHFR) minigene, several scu-PA expressing CHO cell lines were selected and gene-amplified. These recombinant cell lines, NGpUKs, secreted a completely processed scu-PA of 54 kD and up to 60mg/L was accumulated in the culture medium when they were adapted to an optimal MTX concentration. Over 95% of the scu-PA expressed was secreted in the culture medium and identified having the proper function of a plasminogen activator when activated by plasmin. Based on a genomic Southern analysis, a representative subclone, MGpUK-5, exhibited MTX-dependent scu-PA gene amplification, plus the initial single-copy gene of scu-PA eventually turned into about 150 copies of the amplified gene of scu-PA after gradual adaptation to 2.0$\mu$M of MTX. Meanwhile, the transcripts kof the scu-PA gene increased, although -early saturation of transcription was identified at 0.1$\mu$M of MTX. The scu-PA production by the MGpUK-5 subclone also increased relative to the gene amplification and increased transcripts, however, the relationship was not linearly proportional. Accordingly, since the MGpUK cell lines expressed elevated levels of enzymatically active scu-PA, these cell lines could be applied to the largescale production of scu-PA.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.22 no.8
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• pp.1755-1764
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• 1997

In this paper, we proposed the mechanism for the buffer allocation and a cell scheduling method with logical separation a single buffer in the ATm switch, and analyzed the cell loss probability and the delay of each trafic (CBR/VBR/ABR) based on the weighted value and the dynamic cell service scheduling algorithm. The proposed switch buffering system classifies composite trafics incoming to the switch, according to the characteristic of traffic, then stores them in the logically separated buffers, and adopts the round-robin service with weighted value in order to transmit cells in buffers though one output port. We analyzed 4 cell service scheduling algorithms with dynamic round-robinfor each logically separated service line of a single buffer, in which buffers have the respective weighted values and 3 classes on mixed traffic which characteristized by traffic descriptor. In simulation, using SIMCRIPT II.5., we model the VBR and the ABR traffics as ON/OFF processes, and the CBR traffic as a Poisson processes. As the results of analysis according to the proposed buffer management mechanism and cell service algorithm, we have found that the required QoS of each VC can be quaranteed depends on a scale of weighted values allocated to buffers that changed the weighted values, and cell scheduling algorithm.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.3057-3060
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• 2015

Background: Cytological examination of pleural effusions is very important in the diagnosis of malignant lesions. Thoracentesis is the first investigation to be performed in a patient with pleural effusion. In this study, we aimed to compare traditional with cell block methods for diagnosis of lung disease accompanied by pleural effusion. Materials and Methods: A total of 194 patients with exudative pleural effusions were included. Ten mililiters of fresh pleural fluid were obtained by thoracentesis from all patients in the initial evaluation. The samples gathered were divided to two equal parts, one for conventional cytological analysis and the other for analysis with the cell block technique. In cytology, using conventional diagnostic criteria cases were divided into 3 categories, benign, malignant and undetermined. The cell block sections were evaluated for the presence of single tumor cells, papillary or acinar patterns and staining with mucicarmine. In the cell block examination, in cases with sufficient cell counts histopathological diagnosis was performed. Results: Of the total undergoing conventional cytological analyses, 154 (79.4%)were reported as benign, 33 (17%) as malignant and 7 (3.6%) as suspicious of malignancy. With the cell block method the results were 147 (75.8%) benign, 12 (6.2%) metastatic, 4 (2.1%) squamous cell carcinoma, 18 (9.3%) adenocarcinoma, 5 (2.6%) large cell carcinoma, 2 (1%) mesothelioma, 3 (1.5%) small cell carcinoma, and 3 (1.5%) lymphoma. Conclusions: Our study confirmed that the cell block method increases the diagnostic yield with exudative pleural effusions accompanying lung cancer.

• 순환기질환의공학회:학술대회논문집
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• 2005.12a
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• pp.11-12
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• 2005