• 한국작물학회지
• /
• 제43권2호
• /
• pp.64-65
• /
• 1998

The inheritance of resistance to bacterial blight in a Tongil-type rice cultivar 'Changseongbyeo' was studied using a Korean isolate HB9101. which belongs to race $K_1$. The resistance of Changseongbyeo to the HB9101 was controlled by a single dominant gene. This gene was allelic with Xa-1 gene and linked to Ig gene on chromosome 4 with the recombination value of 7.5%.

• International Journal of Industrial Entomology and Biomaterials
• /
• 제3권2호
• /
• pp.187-190
• /
• 2001

Inheritance pattern of resistance to Bombyx mori nuclear polyhedrosis virus (BmNPV) was studied in an Indian silkworm stock TX by single back-cross test method. The resistant parent ［TX］, susceptible parent ［HM］, their Fl, F2, and Fl progeny back-crossed to TX [BC(R)] and HM [BC(S)] were inoculated per os with a fixed concentration of BmNPV($0.5{\times}10^{th} PIB/ml$) on the first day of second stadium. The cumulative mortality was recorded until day $10^{\times}$ post-inoculation. The results show that the resistance to BmNPV in TX fellow mono Mendelian inheritance pattern. The resistance dominated over the susceptibility at Fl. At F2, the resistant and susceptible offspring segregated in 3:1 ratio whereas at BC(S), the resistant and susceptible offspring segregated in 1:1 ratio. The response of BC(R) was more or less like the resistant parent TX which confirms the involvement of a major dominant gene conferring resistance to BmNPV in TX. The possible mechanism of inheritance of resistance in TX is discussed.

• 한국양식학회지
• /
• 제10권4호
• /
• pp.395-402
• /
• 1997

The study has been conducted in order to understand the inheritance of body color in the wild type zebrafish (zebra danio), Danio rerio, and its golden mutant (golden danio). The body color was also studied to determine the effect of golden coloration on the survival rate of zebrafish eggs and larvae up to 15 days after fertilization. Reciprocal monohybrid crosses between the wild and the golden type of zebrafish indicated that golden coloration was controlled by a single gene which had two alleles. Transmission of these alleles from parents to their progenies followed the principles of dominance and segregation based on Mendelian inheritance. Similar results from the reciprocal crosses implied that a locus for golden coloration was located on an autosomal chromosome. On the other hand, average survival rates from four different types of mating between, and within, zebra and golden danio suggested that golden coloration seemed to be associated with the survival rate of zebrafish, especially in its early embryonic stage. This indicated that homozygous recessive golden mutation was likely to weaken the golden danio's chance of survival.

• Journal of Genetic Medicine
• /
• 제3권1호
• /
• pp.15-19
• /
• 1999

We have investigated the genetic variation in the human apo B mRNA editing protein (apobec-1) gene. Exon 3 of the apobec-1 gene was amplified by polymerase chain reaction. After detection of an additional band by single strand conformational polymorphism (SSCP) analysis, sequencing of the SSCP-shift sample revealed a single-base mutation. The mutation was a CGG transversion at codon 80 resulting in a lleRMet substitution. This substitution was confirmed by restriction fragment length polymorphism analysis since a Pvull site is abolished by the substitution. Population and family studies confirmed that the inheritance of the genotypes for apobec-1 gene polymorphism is controlled by two codominant alleles (P1 and P2). A significant difference in plasma triglyceride was detected among the different apobec-1 genotypes in the CAD patients (P<0.05). Our study could provide the basis for elucidating the interaction between genetic variation of the apobec-1 gene and disorders related to lipid metabolism.

• 한국응용곤충학회지
• /
• 제24권4호
• /
• pp.219-222
• /
• 1986

우리나라의 주요(主要) 벼흰잎마름병 저항성(抵抗性) 품종(品種)의 저항성(抵抗性) 유전양식(遺傳樣式)과 저항성(抵抗性) 품종간(品種間)의 대립관계(對立關係)를 분석(分析)하기 위하여 연구(硏究)한 결과(結果)를 요약(要約)하면 다음과 같다. 1. JB8206균주(菌株)에 대(對)한 청청(靑靑)벼, 영풍(永豊)벼, 남풍(南豊)벼, 삼강(三剛)벼, 한강(漢江)찰벼의 흰 잎마름병 저항성(抵抗性)은 1개(個)의 우성유전자(優性遺傳子)에 의(依)해 지배(支配)되었다. 2. JB8206, KN8298균주(菌株)에 대(對)한 백양(白羊)벼와 풍산(豊産)벼의 저항성(抵抗性)은 1개(個)의 우성유전자(優性遺傳子)에 의(依)해 지배(支配) 되었다. 3. JB8206균주(菌株)에 대(對)한 풍산(豊産)벼와 청청(靑靑)벼, 밀양(密陽) 30호(號), 백운(白雲)찰벼의 저항성(抵抗性) 및 수원(水原)312호(號)와 백양(白羊)벼, 백운(白雲)찰벼의 저항성(抵抗性)은 대립관계(對立關係)이었으며 동일유전자(同一遺傳子)로 추정(推定)되었다.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제15권2호
• /
• pp.122-126
• /
• 2012

Benign recurrent intrahepatic cholestasis (BRIC) is a rare autosomal recessive inherited disorder characterized by multiple recurrent episodes of severe cholestatic jaundice without obstruction of extrahepatic bile duct. We present the case of a 7-year-old boy with BRIC confirmed by mutation analysis in the ATP8B1 gene and typical clinical manifestation. Despite inheritance of BRIC, we detected a mutation on only one allele. To our knowledge, this is the first report of BRIC with a confirmed single heterozygote novel mutation in the ATP8B1 gene in Korea.

• 한국육종학회지
• /
• 제42권2호
• /
• pp.188-194
• /
• 2010

시클라멘의 꽃 및 꽃눈의 색, 잎의 모양과 무늬 등의 질적 형질에 대한 유전 분석을 위하여 이들의 특성이 다른 계통을 교잡한 후, $F_1$, $F_2$ 및 여교잡 세대에서 분리비를 조사하였다. 화색은 $F_1$이 양친의 중간색을 나타냈고, $F_2$는 자방친 화색: 중간 색($F_1$과 동일): 화분친 화색이 1: 2 : 1로 분리되어 한 쌍의 대립유전자가 불완전우성으로 유전하는 것으로 나타났다. 꽃눈 색은 흰색 ${\times}$ 빨간색 계통의 조합에서 $F_1$이 빨간색으로 나타났고, $F_2$에서 빨간색 3: 흰색 1로 분리되어 한 쌍의 대립유전자가 우성으로 작용하는 것으로 밝혀졌다. 모인 꽃잎 형태는 흐트러진 꽃잎 형태에 대하여 완전우성으로 유전하는 것으로 나타났다. 잎 형질에 있어서는 넓은 은색 무늬 잎이 선형 무늬 잎에 대하여, 그리고 피침형 잎 끝이 타원형 잎 끝에 대하여 각각 우성으로 작용하는 한 쌍의 대립유전자가 관여하는 것으로 나타났다. 이와 같이 시클라멘의 질적형질의 발현에는 한 쌍의 대립 유전자가 작용하며 꽃의 색은 불완전우성으로, 꽃눈의 색, 잎의 형태 및 무늬는 완전우성으로 유전되는 것으로 밝혀졌다.

• Journal of Genetic Medicine
• /
• 제20권1호
• /
• pp.15-24
• /
• 2023

Monogenic disorders are traditionally attributed to the presence of mutations in a single gene. However, recent advancements in genomics have revealed instances where the phenotypic expression of apparently monogenic disorders cannot be fully explained by mutations in a single gene alone. This review article aims to explore the emerging concept of digenic or oligogenic inheritance in seemingly monogenic disorders. We discuss the underlying mechanisms, clinical implications, and the challenges associated with deciphering the contribution of multiple genes in the development and manifestation of such disorders. We present relevant studies and highlight the importance of adopting a broader genetic approach in understanding the complex genetic architecture of these conditions.

• Current Research on Agriculture and Life Sciences
• /
• 제6권
• /
• pp.71-73
• /
• 1988

고추 줄기의 모용(毛茸)에 대(對)한 유전현상(遺傳現象)을 구명(究明)하기 위하여 342, 김장고추, 남지(南旨), Hungarian Wax등(等) 4품종(品種)과 이들을 교잡(交雜)하여 얻은 $F_1$, $F_2$ 및 $BC_1F_1$에 대(對)해 시험한 결과(結果)를 요약(要約)하면 고추 줄기의 모용(毛茸)이 많은 것이 없는 것에 대(對)하여 우성(優性)이었으며 이 형질(形質)은 단일유전인자(單一遺傳因子)에 의(依)하여 지배(支配)되는 것으로 나타났다.

• 한국연초학회지
• /
• 제6권2호
• /
• pp.185-189
• /
• 1984

To classify the inheritance of resistance to potato virus Y, crosses between susceptible flue-cured tobacco variety NC 95 and resistant variety McNair 30 were conducted. The parents, $F_1$ plants, $F_2$ populations, and haploid plants derived from anthers of $F_1$ plants were screened for a resistance of two potato virus Y strains (PVY-VB and PVY-VN) isolated in Korea. The Chi-square values for the $F_3$ populations and haploids of $F_1$ fitted 1 :3 and 1 :1 ratios of resistant to susceptible for two strains, respectively. Therefore, it was found that the resistance of McNair 30 for the potato virus Y was controlled by a single recessive gene. Moreover the resistance to two strains screened was inherited dependently.