• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.11
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• pp.2158-2165
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• 2007

In this paper, a Modified Fuzzy C-Means algorithm with Gaussian Weights(MFCM_GW) is presented for nonlinear blind channel equalization. The proposed algorithm searches the optimal channel output states of a nonlinear channel from the received symbols, based on the Bayesian likelihood fitness function and Gaussian weighted partition matrix instead of a conventional Euclidean distance measure. Next, the desired channel states of a nonlinear channel are constructed with the elements of estimated channel output states, and placed at the center of a Radial Basis Function(RBF) equalizer to reconstruct transmitted symbols. In the simulations, binary signals are generated at random with Gaussian noise. The performance of the proposed method is compared with those of a simplex genetic algorithm(GA), a hybrid genetic algorithm(GA merged with simulated annealing(SA): GASA), and a previously developed version of MFCM. It is shown that a relatively high accuracy and fast search speed has been achieved.

• Korean Chemical Engineering Research
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• v.44 no.5
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• pp.444-452
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• 2006

This paper reports experimental excess molar volumes $V^E_m$ using a digital vibrating-tube densimeter and excess molar enthalpies $H^E_m$ by means of an isothermal microcalorimeter with a flow mixing cell for the binary mixtures{1,2-dichloropropane + 2-(2-methoxyethoxy)ethanol} and {1,2-dichloropropane + 2-(2-ethoxyethoxy)ethanol} at 298.15 K under atmospheric pressure. All the $V^E_m$ and $H^E_m$ of the two binary mixtures showed S-shaped forms, being negative for poor and positive for rich 1,2-dichloropropane mole fractions. These show that the excess properties were shown to be negative deviation from ideality due to the strong self-association effect among 2-(2-alkoxyethoxy)ethanol molecules at an early stage of mixing, a relatively high energy then is needed to break hydrogen bonds of 2-(2-alkoxyethoxy)ethanol with an increase ofhalogenated hydrocarbon molecular at high mole fraction of 1,2-dichloropropane. The values of excess molar properties($V^E_m$ and $H^E_m$) were fitted by the Redlich-Kister equation using Nelder-Mead's simplex pattern search method. The Wilson, NRTL, and UNIQUAC models were used to correlate the $H^E_m$ values.

• The Journal of Korean Society of Virology
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• v.27 no.2
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• pp.227-237
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• 1997

In order to search for anti-Herpes simplex virus (HSV) type-1 agents from Korean medicinal herbs and Korean traditional prescriptions (herb complexes), we selected 80 medicinal herbs and 45 prescriptions, based on a review of the Korean traditional medicine books. Both methanol extracts and boiling-water extracts were tested by means of the MTT assay (tetrazolium based colorimetric assay). Ten of the 125 methanol extracts: CM-11, CM-18, CM-19, CM-21, CM-22, CM-39, MM-3, MM-18, MM-29, MM-73 (see explanation of nomenclature below), showed efficacy against HSV-1. Twelve of the water extracts: CW-2, CW-3-I, CW-3-II, CW-18, MW-3, MW-5 MW-6, MW-12, MW-47, MW-69, MW-73 and MW-79 were active. #3 (individual herb) and #73 (individual herb) were interesting because both water and methanol extracts were active. Especially, #3 is a part of composition of Hong-il-$laksamd{\check{u}}ngbang$ and Hojanghaedokt'ang which have anti-HSV-1 activitives. The SI value of MW-69 and CW-18 was relative high as $10.2{\pm}0.7$ and $11.8{\pm}2.2$. The cytotoxic effect on Vera cells of $Panch'{\check{o}}nch'onch'{\check{o}}ngbang$, Taraxacum platycarpum H. Dahlst. and acycloguanosine was determined by MTT assay. Water extracts of $Panch'{\check{o}}nch'onch'{\check{o}}ngbang$ (prescription) and Taraxacum platycarpum H. Dahlst. showed very weak cytotoxic effects on Vero cells at > $100\;{\mu}g/ml$ but acycloguanosine showed strang cytotoxic effects on Vera cells at > $100\;{\mu}g/ml$. As a result, #3, #73, MW-69 and CW-18 are considered as potentially useful for anti-HSV-1 agent and will be the focus of further research. Abbreviations: CM - methanol extracts of traditional prescriptions; CW - water extracts of traditional prescriptions; MM - methanol extracts of individual herbs; MW - water extracts of individual herbs.

• International Journal of Fluid Machinery and Systems
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• v.2 no.4
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• pp.392-399
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• 2009

The paper concerns the description of the step by step development process of the new fixed blade runner called "Mixer" suitable for the uprating of the Francis turbines units installed at the older low head hydropower plants. In the paper the details of hydraulic and mechanical design are presented. Since the rotational speed of the new runner is significantly higher then the rotational speed of the original Francis one, the direct coupling of the turbine to the generator can be applied. The maximum efficiency at prescribed operational point was reached by the geometry optimization of two most important components. In the first step the optimization of the draft tube geometry was carried out. The condition for the draft tube geometry optimization was to design the new geometry of the draft tube within the original bad draft tube shape without any extensive civil works. The runner blade geometry optimization was carried out on the runner coupled with the draft tube domain. The blade geometry of the runner was optimized using automatic direct search optimization procedure. The method used for the objective function minimum search is a kind of the Nelder-Mead simplex method. The objective function concerns efficiency, required net head and cavitation features. After successful hydraulic design the modal and stress analysis was carried out on the prototype scale runner. The static pressure distribution from flow simulation was used as a load condition. The modal analysis in air and in water was carried out and the results were compared. The final runner was manufactured in model scale and it is going to be tested in hydraulic laboratory. Since the turbine with the fixed blade runner does not allow double regulation like in case of full Kaplan turbine, it can be profitably used mainly at power plants with smaller changes of operational conditions or in case with more units installed. The advantages are simple manufacturing, installation and therefore lower expenses and short delivery time for turbine uprating.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.3
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• pp.215-222
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• 2001

Neural network based models of semiconductor manufacturing processes have been shown to offer advantages in both accuracy and generalization over traditional methods. However, model development is often complicated by the fact that back-propagation neural networks contain several adjustable parameters whose optimal values unknown during training. These include learning rate, momentum, training tolerance, and the number of hidden layer neurOnS. This paper presents an investigation of the use of genetic algorithms (GAs) to determine the optimal neural network parameters for the modeling of plasma-enhanced chemical vapor deposition (PECVD) of silicon dioxide films. To find an optimal parameter set for the neural network PECVD models, a performance index was defined and used in the GA objective function. This index was designed to account for network prediction error as well as training error, with a higher emphasis on reducing prediction error. The results of the genetic search were compared with the results of a similar search using the simplex algorithm.

• Journal of the Society of Naval Architects of Korea
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• v.29 no.2
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• pp.115-122
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• 1992

A sandwich element is a special Hybrid structural form of the composite construction, which is consisted of three main parts : thin, stiff and relatively high density faces separated by a thick, light, and weaker core material. In a sandwich construction, the shear deformation of the faces. Therefore, in the calculation of the bending stiffness, the shear effect should be included. In this paper, the minimum weight is selected as an object function, as the weight critical structures are usually composed of these kind of construction. To obtain the minimum weight of sandwich panel, the principle of minimum potential energy is used and as for the design constraints, the allowable bending stress of face material, the allowable shear stress of core material, the allowable value of panel deflection and the wrinkling stress of faces are adopted, as well as the different boundary conditions. For the engineering purpose of sandwich panel design, the results are tabulated, which are calculated by using the nonlinear optimization technique SUMT.

• Korean Journal of Oriental Medicine
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• v.1 no.1
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• pp.495-508
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• 1995

In order to search for anti-HSV agents from natural complex products, we extended the number of specimens. Both methanol extract and boiling water extract of the natural complex products were screened to detect anti-HSV activity by MTT assay. Anti-HSV activities of thirteen natural complex products extracted by methanol and boiling water were screened. Three of 13 natural complex products extracted by methanol showed efficacy against HSV. Natural complex products showing anti-HSV activities as methanol extracts were No.3, 6, 11 and their Sl were 323.809, 2811.041 and 708.20. As water boiling extracts, No.8 and No.11 have displayed Sl of 16.45 and 60.39 respectively. Especially anti-HSV activities of natural complex products extracted by methanol No.6 was stronger than other ones.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1998.04a
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• pp.444-449
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• 1998

A modal transducer in two-dimensional structure can be implemented by varying the distributed transducer's gain spatially. In this paper, a method based on finite element method is developed for optimizing spatial gain distribution of PVDF transducer to create the modal transducer for specific modes. Using this concept, one can design the modal transducer in two-dimensional structure having arbitrary geometry and boundary conditions. As a practical means for implementing this continuous gain distribution without repoling die PVDF film, the gain distribution is approximated by optimizing gain-weights of interface circuit. The whole spatial area of the PVDF film is divided into several electrode segments and the signals from each segment are properly weighted and summed by interface circuit. This corresponds to the approximation of a continuous function using discrete values. The electrode partition is optimized using the genetic algorithm. Gain-weights are optimized using the simplex search method. A modal sensor for first to fourth modes of aluminum plate is designed using PVDF film with gain-weighted interface circuit. Various lamination angles of PVDF film are taken into consideration to utilize the anisotropy of the PVDF film. Performance of the optimized' PVDF sensor is demonstrated by numerical simulations..

• Journal of Microbiology and Biotechnology
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• v.25 no.10
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• pp.1714-1727
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• 2015

This work describes a new strategy for optimal design of Multiplex-PCR primer sequences. The process is based on the Particle Swarm Optimization-Simplex algorithm (Mult-PSOS). Diverging from previous solutions centered on heuristic tools, the Mult-PSOS is selfconfigured because it does not require the definition of the algorithm's initial search parameters. The successful performance of this method was validated in vitro using Multiplex-PCR assays. For this validation, seven gene sequences of the most prevalent bacteria implicated in urinary tract infections were taken as DNA targets. The in vitro tests confirmed the good performance of the Mult-PSOS, with respect to infectious disease diagnosis, in the rapid and efficient selection of the optimal oligonucleotide sequences for Multiplex-PCRs. The predicted sequences allowed the adequate amplification of all amplicons in a single step (with the correct amount of DNA template and primers), reducing significantly the need for trial and error experiments. In addition, owing to its independence from the initial selection of the heuristic constants, the Mult-PSOS can be employed by non-expert users in computational techniques or in primer design problems.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.2 no.3
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• pp.359-365
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• 1998

The portable two way radio telephone amongst GMDSS equipment in the vessel is very important portable wireless one for search and rescue in distress situation. Although the portable two way radio telephone must be equipped with in the vessel by IMO & RR, other kinds of wireless tranceivers are widely used to communicate with crew members who are separately appointed at bridge forecastle and poop in leaving or arriving at the port, passing through a narrow canal or voyaging in the foggy weather, Most of those wireless tranceivers except portable two way radio telephone are allocated at 27MHz band with PTT simplex system that makes crew members difficult to work effectively in the vessel. In this research 900MHz band FDD(frequency duplex division) tranceiver system is studied to help crew members in the vessel to communicate with themselves freely and to work easily meanwhile with simple operation. 900MHz band FDD tranceiver system uses one chip FM frontend IC to realize the miniaturization and downsizing of tranceiver and small size head set attached to helmet. The credibility of this research's result is highly evaluated by circuit analysis with computer aided simulation, and partly modified 900MHz band cordless phone circuit.