• Title/Summary/Keyword: Significance testing

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Clinical Significance of Atypical Squamous Cells of Undetermined Significance among Patients Undergoing Cervical Conization

  • Nishimura, Mai;Miyatake, Takashi;Nakashima, Ayaka;Miyoshi, Ai;Mimura, Mayuko;Nagamatsu, Masaaki;Ogita, Kazuhide;Yokoi, Takeshi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8145-8147
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    • 2016
  • Background: Atypical squamous cells of undetermined significance (ASCUS) feature a wide variety of cervical cells, including benign and malignant examples. The management of ASCUS is complicated. Guidelines for office gynecology in Japan recommend performing a high-risk human papillomavirus (HPV) test as a rule. The guidelines also recommend repeat cervical cytology after 6 and 12 months, or immediate colposcopy. The purpose of this study was to determine the clinical significance of ASCUS. Materials and Methods: Between January 2012 and December 2014, a total of 162 patients underwent cervical conization for cervical intraepithelial neoplasia grade 3 (CIN3), carcinoma in situ, squamous cell carcinoma, microinvasive squamous cell carcinoma, and adenocarcinoma in situ at our hospital. The results of cervical cytology prior to conization, the pathology after conization, and high-risk HPV testing were obtained from clinical records and analyzed retrospectively. Results: Based on cervical cytology, 31 (19.1%) of 162 patients were primarily diagnosed with ASCUS. Among these, 25 (80.6%) were positive for high-risk HPV, and the test results of the remaining 6 patients (19.4%) were uncertain. In the final pathological diagnosis after conization, 27 (87.1%) and 4 patients (12.9%) were diagnosed with CIN3 and carcinoma in situ, respectively. Conclusions: Although ASCUS is known as a low-risk abnormal cervical cytology, approximately 20% of patients who underwent cervical conization had ASCUS. The relationship between the cervical cytology of ASCUS and the final pathological results for CIN3 or invasive carcinoma should be investigated statistically. In cases of ASCUS, we recommend HPV tests or colposcopic examination rather than cytological follow-up, because of the risk of missing CIN3 or more advanced disease.

Statistical analysis on a specific student group and their responses to sub-health questionnaire (특정 수강집단 학생들과 아건강 설문지 응답과의 통계적 분석)

  • Shin, Jae-Kyoung
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.4
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    • pp.895-906
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    • 2015
  • Nowadays, many people have much interest in health and quality of life. They can get information on foods known to have remedial value for certain illness from many healthcare experts on TV health related shows. Moreover, a lot of studies on these foods and their remedial value are consistently published. Thus, this study, on the ground that if we know prognosis of a certain disease in advance we can lead a better life without suffering from diseases, statistically analyzes specific students' responses to sub-health questionnaire. The analysis reveals that results of testing the equality of gender and 10 diagnosis indexes shows significant difference within 5% of significance level in 9 diagnosis indexes except for respiratory system. And the result of testing the equality of age and 10 diagnosis indexes indicates that there is no significant difference within 5% of significance level. In the study, students are divided into two age category. However, the age of 20s could be regarded as one category, which could be the reason why there is no significant difference.

Study on The Customer Service of Hospitals and Clinics According to Franchised Form or Not

  • Lee, Kyung-Soo;Nam, Seok-Woo;Choi, Young-Soo
    • Journal of Korean Clinical Health Science
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    • v.2 no.2
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    • pp.148-157
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    • 2014
  • Purpose. This study compares and analyzes customer service on customer satisfaction and customer royalty on customer satisfaction targeting the customers visiting a hospital or a clinic which is franchised or not. And it aims at helping business rationalization for a medical institution. Methods. This paper conducts a survey and selects a sample of 670 customers except the missing value targeting the customers of 4 primary health care institutions and 4 bigger health care institutions in Seoul and Gyeonggi province. It conducts frequency analysis for the purpose of investigating the respondents' generic characteristic and factor of their medical institution selection, and factor analysis, reliability analysis and regression analysis for the hypothesis testing. Results. The first hypothesis testing result is significant in level of significance of 0.01. The second one is the same as the first one, but the dummy variable shows a negative regression coefficient(-0.479). The third one is significant in level of significance of 0.01, but the forth one is not significant. And the respondents prioritize website(Home page) and convenience in use of a hospital procedure for selecting a hospital or a clinic. Conclusions. The additional analysis finds that the franchised group has more satisfaction than none franchised group. But in case of their royalty, the average of franchised and none franchised groups are not significantly different. Therefore, the results of this paper reveal to support the results of the advanced researches.

The Effects of Moxibustion on Heart Rate Variability in Cancer Patients (쑥뜸치료가 암환자의 심박변이도에 미치는 영향)

  • Kim, Ok-Hee;Choi, Jung-Eun;Yoon, Jeung-Won;Yoo, Hwa-Seung
    • Journal of Korean Traditional Oncology
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    • v.16 no.1
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    • pp.15-31
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    • 2011
  • Objective : The study aims to investigate the effect of moxibustion treatments on autonomic nervous system function of cancer patients through the evaluation of heart rate variability (HRV) biofeedback testing. Materials and Methods : Six cancer patients from inpatient care unit of Dunsan Oriental Hospital, Daejeon University were given three moxibustion treatment sessions every other day over one week period on five Oriental Medicine meridian points CV4, CV6, CV12, KD1, and PC8. HRV biofeedback was conducted before and after each treatment sessions. Three areas of analyses were done from the test conducted; Time Domain Analysis, Frequency Domain Analysis and Autonomic Nervous System (ANS) balance analysis. Results : Time Domain Analysis has shown increased Standard Deviation of all Normal R-R Intervals (SDNN), and decreased Mean Heart Rate and Physical Stress Index (PSI) levels, with statistical significance (P<0.05). In Frequency Domain Analysis, series of moxa treatments have increased Total Power (TP), Very Low Frequency Oscillation Power (VLF), High Frequency Oscillation Power (HF), normalized HF values while decreasing Low Frequency Oscillation Power (LF), normalized LF and LF/HF ratio with statistical significance (P<0.05). The values of ANS activity, ANS balance, Stress resistance, Stress index, have also shown significant changes. For cardiac stability stroke volume power (SP) and Blood Vessel Tension (BVT) were followed, which were both increased after treatment. All changes were statistically significant (P<0.05). Conclusion : The results have shown a positive correlation between the moxibustion treatments and autonomic nervous system responses on cancer patients through the HRV biofeedback testing. This study suggests possible application of moxibustion treatments for managing ANS functions of cancer patients, although additional studies with larger population are necessary to confirm the data.

Comparision of Effectiveness between the $ThinPrep^{(R)}$ and the Cytospin Preparations of the Repeated Urine Cytology (소변검사의 재검 시 세포원심분리법과 액상세포검사 $ThinPrep^{(R)}$의 효율성에 관한 비교)

  • Kim, Hyun-Kyung;Pyo, Ju-Yeon;Lee, Yoon-Hee;Jung, Woo-Hee;Kim, Se-Hoon;Hong, Soon-Won
    • The Korean Journal of Cytopathology
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    • v.18 no.1
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    • pp.55-61
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    • 2007
  • Once diagnosed as "cell paucity"or "atypia" by the cytospin (CS) preparation, this CS preparation does not secure a precise diagnosis by repeated testing alone. Although the ThinPrep (TP) preparation is acknowledged to show increased cellularity, performing the screening tests for the cases that have enough cellularity, according to CS, raises issues for the cost-effectiveness. To obtain a more precise diagnosis through increasing the cellularity by performing TP, we selected the cases that were diagnosed as "cell paucity" or "atypia" by CS, but they required a more precise diagnosis, and the samples were processed via both CS and TP to compare the results. 11 patients diagnosed as "cell paucity" and 22 patients diagnosed as "atypia" by CS participated in this study. When the detection rate of atypical cells in both preparations with repeated urine cytology was compared, the overall detection rate of TP (16cases, 48.5%) was superior than that of CS (11cases, 33.3%), with statistical significance. The cellularity of both preparations was compared on repeated urine cytology; the general cellularity of TP (29cases, 87.9%) was higher than that of CS (20cases, 60.6%), but there was no statistical significance. Particularly, we repeated the TP for the 1 case that was diagnosed as "atypia" and we performed polyoma virus immunohistochemical staining, which confirmed polyoma virus. In conclusion, we can avoid obtaining negative diagnosis from cases with uncertain "atypia" or "cell paucity" by performing repeated TP testing.

Introduction to Improve for Testing Method of National Technology Qualification to Meet Demands From the era of Knowledge & Information (지식.정보화시대에 요구되는 국가기술자격 검정방법 도입을 위한 연구 - 기능장, 기사, 산업기사, 기능사를 중심으로 -)

  • Cho Jeong-Yoon;Park Jong-Sung;Kim Deog-Ki;Kim Hyun-Soo
    • Journal of Engineering Education Research
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    • v.4 no.1
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    • pp.57-78
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    • 2001
  • Due to developments in information technology and ensuing changes in the concept of time and space, the significance of national boundaries has been weakened, bringing to attention the heightened competition among nations. In order to respond to these transformations, the Korean government is increasing its efforts to raise the authenticity of the National Technology Qualification System(NTQS) by closely linking NTQS testing method and procedure to practical knowledge and skills in the industry field. This initiative is based on the recognition that the human resources development is a crucial factor in determining a nation's competitiveness. This study aimed, first of all, to diagnose the problems directly and indirectly affecting the testing method in the current NTQS. And then, differentiated solutions according to grade and improvements in the testing infrastructure were suggested. The ultimate purpose was to provide a blueprint for enhancing national competitiveness through increased authenticity and efficiency of the NTQS. Research methods applied during this study include: the collection and review of qualification-related literature; a series of conferences with leading experts; interviews with vocational educators and researchers from qualification-related institutes; a survey of national qualification holders from a variety of professions and industries; and participatory observation at qualification exam centers. This research suggested policy recommendations as follows; First, measures to improve for testing method of professional engineer Second, measures to improve for testing method of Master craftsman Third, measures to improve for testing method of Engineer, Industrial Engineer, Craftsman Fourth, plans for the establishment of operation system for a computerized testing Fifth, institutional perspective on establishing qualification infrastructure Sixth, operational perspective on establishing qualification infrastructure

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Significance of Repeated Polymerase Chain Reaction (PCR) Testing for Diagnosis of Pulmonary Tuberculosis (폐결핵 진단 시 중합효소연쇄반응검사 반복 시행의 의의)

  • Kim, Soo-Ok;Kim, Yoon-Hee;Chi, Su-Young;Ban, Hee-Jung;Oh, In-Jae;Kwon, Yong-Soo;Kim, Kyu-Sik;Kim, Yu-Il;Lim, Sung-Chul;Kim, Young-Chul
    • Tuberculosis and Respiratory Diseases
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    • v.68 no.6
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    • pp.345-349
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    • 2010
  • Background: The polymerase chain reaction (PCR) test is important for the confirmatory diagnosis of tuberculosis (TB) caused by Mycobacterium tuberculosis. The aim of this study was to analyze the yield of repeated PCR testing in patients with confirmed pulmonary TB. Methods: The medical records of 130 patients, who had more than two consecutive PCR tests and a M. tuberculosis-positive sputum culture from August, 2006 to December, 2007, were retrospectively reviewed for the purposes of this study. A positive TB-PCR test was defined as at least one positive test result. Results: The cumulative positive PCR test rate was 80% (104/130), with gradually increasing rates of positive findings upon the first, second and third TB-PCR tests with 52.3%, 68.5% and 75.4%, respectively. However, further testing did not increase the positive rate further. Conclusion: Repeated PCR testing at least three times for M. tuberculosis is helpful for diagnosis of pulmonary TB.

Significance Analysis of Yellow Dust Related Disease Using Tweet Data (트윗 데이터를 이용한 황사 관련 질병 유의성 분석)

  • Jung, Yong-Han;Seo, Min-Song;Yoo, Hwan-Hee
    • Journal of Cadastre & Land InformatiX
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    • v.47 no.1
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    • pp.267-276
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    • 2017
  • Damages have occurred in various fields such as agriculture, industry, and citizen's health due to the yellow dust. Therefore, it is urgent to take measures against it. In this regard, this study collected data of yellow dust over 11 days on a basis of Feb. 23. 2015 when yellow dust was the greatest after 2009, issue words analysis and recomposed health related tweet data. After testing the significance of yellow dust related diseases by association rule analysis with diseases, it obtained the study results as follows: As a result of significance test for the patients with rhinitis, asthma and conjunctivitis by acquiring the condition data of patients from the Health Insurance Review & Assessment Service, conjunctivitis appeared to be significant in 13 cities for 16 cities at 5% significance probability, while asthma and rhinitis showed a significance in 3 and 6 areas. As described above, it is possible to obtain information about citizens' health from SNS data, such as Tweet data and it is judged that these data will provide useful information for establishing measures of citizens' health care.

ASSESSMENT OF CHILDREN WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER (주의력결핍과잉활동 장애의 평가)

  • Oh, Kyung-Ja
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.1 no.1
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    • pp.65-76
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    • 1990
  • Behavioral characteristics of Attention Deficit Hyperactivity Disorder (ADHD) are aften observed in normal children. As a result, it is at times difficult to distinguish behavior disorder of clinical significance and normal developmental phenomenon. In addition, symptoms of ADHD can vary greatly depending on situations and social context, creating considerable difficulties in assessment. Therefore it is important to obtain information from various sources and in diverse situations. It is also desirable to quantify the severity of the problems whenever possible and determine their clinical significance by comparing the data to developmental norms. Specifically, various assessment methods such as interview with parent and child, behavior rating scales, behavioral observation and psychological testing were reviewed with discussion on merits and limitatious of each. It was emphasized that systematic and comprehensive assessment utilizing appropriate methods is necessary for accurate diagnosis and treatment evaluation of ADHD.

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Contract Awarding Process and its Reasonable Improvement for Defense Acquisition (공공사업 경쟁입찰에서 낙찰자 결정방법분석 및 국방획득사업의 합리적인 사업자결정 방안)

  • Eo, Hajoon;Kim, Sung-Chul
    • Journal of Information Technology Services
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    • v.14 no.2
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    • pp.69-86
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    • 2015
  • The current contract awarding process regulated by laws and ordinances is analyzed and more reasonable processes are suggested. To this end, the principle of economic analysis is described with emphasis on the cost-effectiveness analysis, and the laws and ordinances regulating the process are thoroughly examined. The current contract awarding rule is based on the weighted sum of effectiveness score and cost score. This may not conform to the framework of economic analysis where effectiveness is supposed to be measured as an output and cost measured as an input. An improvement is attempted to the defense acquisition system and it is recognized that the economic analysis and policy consideration should be performed separately. Concept of statistical testing is introduced to see if the results of the cost effectiveness analyses show the significant difference between the alternatives. It is suggested that the contract awarding process can be improved by performing significance test followed by the aggregation of the two analyses. A minor improvement is also suggested on the application of current rules.