• Title/Summary/Keyword: Signal Treatment

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Prevalence of incidental distal biceps signal changes on magnetic resonance imaging

  • Eugene Kim;Joost T.P. Kortlever;Amanda I. Gonzalez;David Ring;Lee M. Reichel
    • Clinics in Shoulder and Elbow
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    • v.26 no.3
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    • pp.260-266
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    • 2023
  • Background: Knowledge of the base rate of signal changes consistent with distal biceps tendinopathy on magnetic resonance imaging (MRI) has the potential to influence strategies for diagnosis and treatment of people that present with elbow pain. The aim of this study is to measure the prevalence of distal biceps tendon signal changes on MRIs of the elbow by indication for imaging. Methods: MRI data for 1,306 elbows were retrospectively reviewed for mention of signal change in distal biceps tendon. The reports were sorted by indication. Results: Signal changes consistent with distal biceps tendinopathy were noted in 197 of 1,306 (15%) patients, including 34% of patients with biceps pain, 14% of patients with unspecified pain, and 8% of patients with a specific non-biceps indication. Distal biceps tendon changes noted on radiology reports were associated with older age, male sex, and radiologists with musculoskeletal fellowship training. Conclusions: The finding that distal biceps MRI signal changes consistent with tendinopathy are common even in asymptomatic elbows reduces the probability that symptoms correlate with pathology on imaging. The accumulation of signal changes with age, also independent of symptoms, suggests that tendon pathology persists after symptoms resolve, that some degree of distal biceps tendinopathy is common in a human lifetime, and that tendinopathy may often be accommodated without seeking care. Level of evidence: IV.

Nutritive Value and Utilization of Three Grass Species by Crossbred Anglo-Nubian Goats in Samoa

  • Aregheore, Eroarome Martin
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.10
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    • pp.1389-1393
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    • 2001
  • A study was carried out to investigate the nutritive value and utilization of three grass species, batiki grass (lschaemum aristatum var. indicum), guinea grass (Panicum maximum) and signal grass (Bracharia decumbens) by growing goats. Eighteen growing crossbred goats $(Anglo-Nubian{\times}Fiji\;local)$ of between 9-11 months of age and pre-trial average live weight of $9.50{\pm}1.60kg$ were divided on the basis of weight to three treatment groups in a completely randomized design. The grasses constituted the diets and they were harvested fresh and chopped into pieces before they were offered to the goats. Chemical composition of the grasses, DMI, body weight gain (BWG) and apparent nutrient digestibility coefficients were measured. The grasses had similar DM content. The CP content of the grasses was in the range of 8.3-11.2%. Crude fiber (CF) content was between 30.9-35.2%. Ether extract (EE) was low with a range of 1.2-1.8%. Nitrogen free extract (NFE) was similar (40.9%) for batiki and guinea grasses, while signal grass had more NFE content (51.1%). The grasses are good sources of minerals (ash). OM content was higher in signal grass while guinea and batiki grasses had similar OM content. The goats on signal grass had higher DMI than those on batiki and guinea grasses (p<0.05). The goats on batiki grass had lower average BWG (p<0.05) than those on guinea and signal grasses. Nutrients digestibility were significantly (p<0.05) higher in the goats on signal grass compared to those on guinea and batiki grasses. The goats on guinea grass were better (p<0.05) in the digestibility of CP, OM, NFE and ME than those on batiki grass. However, goats on batiki were significantly better (p<0.05) in digestibility of CF than those on guinea grass. Signal and guinea grasses had more DCP than batiki grass. DE was lower in batiki grass (p<0.05) than in guinea and signal grasses. There was no significant difference (p>0.05) between batiki and guinea grasses in TON. Data obtained in this experiment demonstrated that signal grass is better than guinea and signal in the nutrition of growing goats in the tropical environment of Samoa. It had the highest nutritive value, better apparent digestibility coefficients which have better growth rate and feed efficiency. In ranking, signal grass was better than guinea and batiki grasses, while guinea grass was better than batiki in nutritive value in the parameters measured. For future pasture establishment in Samoa, signal grass is recommended for consideration because of its higher nutritive value as a replacement for batiki, the most predominant grass.

The control signal construction for multi channel X-ray detector signal acquisition (다채널 X-선 검출기 신호 획득을 위한 제어 신호 구성)

  • Yi, Yun;Kim, Sung-Won;Lee, Sun-Wha;Seo, Min-Seog;Lee, Hyun-Woo;Moon, Seon-Ho;Han, Bum-Soo;Kim, In-Soo
    • Proceedings of the IEEK Conference
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    • 2003.07c
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    • pp.2839-2842
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    • 2003
  • The paper is proposed for control signals to operate X-ray detector signal acquisition system There are control signals and synchronized signals for data acquisition system. X-ray detector signal acquisition system is divided into pre-treatment part which is to amplify acquired dual 16 channel analog input, converter pan which is to multiplex, and convert data and transmit part that combine transferred data output and address in order. It also describes detailed control signals.

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Interference of Fisetin with Targets of the Nuclear Factor-κB Signal Transduction Pathway Activated by Epstein-Barr Virus Encoded Latent Membrane Protein 1

  • Li, Rong;Liang, Hong-Ying;Li, Ming-Yong;Lin, Chun-Yan;Shi, Meng-Jie;Zhang, Xiu-Juan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9835-9839
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    • 2014
  • Fisetin is an effective compound extracted from lacquer which has been used in the treatment of various diseases. Preliminary data indicate that it also exerts specific anti-cancer effects. However, the manner in which fisetin regulates cancer growth remains unknown. In this study, we elucidated interference of fisetin with targets of the nuclear factor ${\kappa}B$ signal transduction pathway activated by Epstein-Barr virus encoding latent membrane protein 1 (LMP1)in nasopharyngeal carcinoma (NPC) cells, Results showed that fisetin inhibited the survival rate of CNE-LMP1 cells and NF-${\kappa}B$ activation caused by LMP1. Fisetin also suppressed nuclear translocation of NF-${\kappa}B$ (p65) and $I{\kappa}B{\alpha}$ phosphorylation, while inhibiting CyclinD1, all key targets of the NF-${\kappa}B$ signal transduction pathway. It was suggested that interference effects of fisetin with signal transduction activated by LMP1 encoded by the Epstein-Barr virus may play an important role in its anticancer potential.

Air-Gap Signal Treatment based Fuzzy Rule in Rail-Joint (Rail-Joint에서 퍼지룰을 기반으로하는 공극신호처리법)

  • Sung, H.K.;Jho, J.M.;Lee, J.M.;Bae, D.K.;Kim, B.S.;Shin, B.C.
    • Proceedings of the KIEE Conference
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    • 2006.07b
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    • pp.1071-1072
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    • 2006
  • Maglev using EMS becomes unstable by unexpected big air-gap disturbance. The main causes of the unexpected air-gap disturbance are step-wise rail joint and large distance between rail splices. For the stable operation of the Maglev, the conventional system uses the threshold method, which selects one gap sensor among two gap sensors installed on the magnet to read the gap between magnet and guide rail. But the threshold method with a wide bandwidth makes the discontinuous air-gap signal at the rail joints because of the offset in air gap sensors and/or the step-wise rail joins. Further more, in the case of the one with a narrow bend-width, it makes Maglev system unstable because of frequent alternation. In this paper, a new method using fuzzy rule to reduce air-gap disturbances proposed to improve the stability of Maglev system. It treats the air-gap signal from dual gap sensors effectively to make continuous signal without air gap disturbance. Simulation and experiment results proved that the proposed scheme was effective to reduce air-gap disturbance from dual gap sensors in rail joints.

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The Effects of Injinchunggantang on Interferon Signaling Pathway of HepG2 Cells (인진청간탕(茵蔯淸肝湯)이 HepG2 cell의 인터페론 신호전달계에 미치는 영향)

  • Yi, Jong-Hoon;Kim, Young-Chul;Lee, Jang-Hoon;Woo, Hong-Jung
    • The Journal of Internal Korean Medicine
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    • v.26 no.1
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    • pp.74-92
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    • 2005
  • Objectives/Methods : To analyze the effect of Injinchunggantang(IJCGT) to Interferon-${\alpha}/{\beta}$ signal transmission system in HepG2 cells, HepG2 Cell were treated with IJCGT. Also, revelation of MxA, 2'5'-OAS mRNA leaded by Interferon-${\alpha}/{\beta}$ and revelation and activation of Jak1, TYK1, and STAT 1, all main signal transmission factors, were analyzed. Results : The analysis resulted in the following 1. With interferon ${\alpha}/{\beta}$ there was no affect cell propagation of Hep G2 cells. With IJCGT alone, cell propagation of HepG2 was promoted, and cell propagation control function was recovered. 2. With interferon ${\alpha}/{\beta}$ cell death was unaffected. With IJCGT apoptosis of HepG2 cell was restrained, and the cell's reaction to interferon was unaffected. 3. With interferon ${\alpha}/{\beta}$ treatment mRNA revelation of MxA and 2'5'-OAS was induced. When HepG2 cells were injected with IJCGT without interferon ${\alpha}/{\beta}$ treatment, mRNA revelation of MxA and 2'5'-OAS increased in proportion to the treatment density. With pre-treatment of IJCGT, leaded with interferon ${\alpha}/{\beta}$, promoted revelation of MxA, 2'5' -OAS mRNA. 4. Though mRNA revelation of lakl, TYK1 and STAT1 was unaffected with IJCGT, activation of STAT1 was promoted with an increase of phosphorylation of STAT1 protein. With pre-treatment of IJCGT, Jak1, TYK2, STAT1 phosphorylation, leaded with interferon, strengthened. 5. TNF-a, IL-1b and LPS present, revelation of MxA and 2'5'-OAS mRNA leaded by interferon was restrained when HepG2 cells were treated with IJCGT, and the interferon signal transmission system restraint action leaded by inflammatory cytokines was moderated. Conclusion : These results support a role for IJGCT in promotion of anti-virus action through maintainance of the liver's sensibility toward interferon. A clinical study of an interferon treated patient treated also with IJGCT is needed to determine its efficacy.

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A Role for the Carbohydrate Portion of Ginsenoside Rg3 in Na+ Channel Inhibition

  • Kim, Jong-Hoon;Hong, Yoon-Hee;Lee, Jun-Ho;Kim, Dong-Hyun;Nam, Ghilsoo;Jeong, Sang Min;Lee, Byung-Hwan;Lee, Sang-Mok;Nah, Seung-Yeol
    • Molecules and Cells
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    • v.19 no.1
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    • pp.137-142
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    • 2005
  • We showed recently that ginsenosides inhibit the activity of various types of ion channel. Here we have investigated the role of the carbohydrate component of ginsenoside $Rg_3$ in the inhibition of $Na^+$ channels. The channels were expressed in Xenopus oocytes by injecting cRNAs encoding rat brain Nav1.2 ${\alpha}$ and ${\beta}1$ subunits, and analyzed by the two-electrode voltage clamp technique. Treatment with $Rg_3$ reversibly inhibited the inward $Na^+$ peak current ($I_{Na}$) with an $IC_{50}$ of $32.2{\pm}4.5{\mu}M$, and the inhibition was voltage-dependent. To examine the role of the sugar moiety, we prepared a straight chain form of the second glucose and a conjugate of this glucose with 3-(4-hydroxyphenyl) propionic acid hydrazide (HPPH). Neither derivative inhibited $I_{Na}$. Treatment with the carbohydrate portion of ginsenoside $Rg_3$, sophorose [${\beta}-D-glucopyranosyl$ ($1{\rightarrow}2$)-${\beta}-glucopyranoside$], or the aglycone (protopanaxadiol), on their own or in combination had no effect on $I_{Na}$. These observations indicate that the carbohydrate portion of ginsenoside $Rg_3$ plays an important role in its effect on the $Na^+$ channel.

Prototype of Emotion Recognition System for Treatment of Autistic Spectrum Disorder (자폐증 치료를 위한 감성인지 시스템 프로토타입)

  • Chung, Seong Youb
    • Journal of Institute of Convergence Technology
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    • v.1 no.2
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    • pp.1-5
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    • 2011
  • It is known that as many as 15-20 in 10,000 children are diagnosed with autistic spectrum disorder. A framework of the treatment system for children with autism using affective computing technologies was proposed by Chung and Yoon. In this paper, a prototype for the framework is proposed. It consists of emotion stimulating module, multi-modal bio-signal sensing module, treatment module using virtual reality, and emotion recognition module. Primitive experiments on emotion recognition show the usefulness of the proposed system.

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A Study on Efficient Frequency Control of Transducer for Skin Treatment Using Multi-Frequency Ultrasound (멀티주파수 초음파를 사용하는 피부 치료기기 트랜스듀서의 효율적인 주파수 제어 연구)

  • Park, Jong-Cheol;Kim, Min-Sung
    • Journal of Korea Multimedia Society
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    • v.25 no.8
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    • pp.1038-1048
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    • 2022
  • Ultrasound is one of the effective methods for skin treatment. The skin penetration depth of the ultrasound depends on the ultrasonic frequency, that is, when the ultrasonic frequency is high, the depth is shallow. We have developed a transducer which can generate effectively 3 different ultrasonic frequencies removing interference between 3 types of frequencies according to impedance matching technology. The generated powers of transducer are 40.67W at 3.MHz, 17.46W at 11.7 MHz, and 14.79W at 21.5 MHz. The signal interference between the three frequencies is designed so that they do not interfere with each other by separating the signals using the SPDT (Single Pole, Double Throw) switch. The developed hybrid ultrasound transducer can be applied in skin care or skin treatment and beauty therapy.

Design and Fabrication of Ballast Water Treatment System using Fuzzy PID Controller (퍼지 PID 제어 기법을 이용한 선박평형수 처리 시스템 설계 및 제작)

  • Lee, Young-Dong;Ahn, Byeong-Gu;Noh, Yun-Hong;Jeong, Do-Un
    • Journal of the Institute of Convergence Signal Processing
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    • v.16 no.3
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    • pp.108-114
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    • 2015
  • Ballast water is carried by ships to ensure stability, trim and structural integrity. When a ship loads cargo, the ballast water is discharged. When foreign marine microorganisms are introduced into new marine environments, they pose a threat to the local marine ecological system. UV system is commonly used for the disinfection of waste and surface water. This method would not be as efficient because some species do survive to form viable populations, much of the sediment and organisms at the bottom of tanks, and may become serious pests. In this paper, we designed and implemented ballast water treatment system using fuzzy PID controller to prevent lamp damage, and to reduce the formation of the viable populations. The experiments were conducted with ballast water treatment system using fuzzy PID controller with short time exposure to the temperature above $40^{\circ}C$. This system was shown to be effective by significantly reducing bacterial population and lamp life extension through appropriate temperature of ballast water.