• MALSORI
• /
• no.64
• /
• pp.121-135
• /
• 2007

Speech signal is distorted by channel characteristics or additive noise and then the performances of speaker or speech recognition are severely degraded. To cope with the noise problem, we propose a modified HMM decoder algorithm using SNR-based observation confidence, which was successfully applied for GMM in speaker identification task. The modification is done by weighting observation probabilities with reliability values obtained from SNR. Also, we apply PSO (particle swarm optimization) method to the confidence function for maximizing the speaker identification performance. To evaluate our proposed method, we used the ETRI database for speaker recognition. The experimental results showed that the performance was definitely enhanced with the modified HMM decoder algorithm.

• BMB Reports
• /
• v.34 no.2
• /
• pp.95-101
• /
• 2001

Tissue transglutaminase (TGII, $G{\alpha}h$) belongs to a family of enzymes which catalyze post-translational modification of proteins by forming isopeptides via $Ca^{2+}$-dependent reaction. Although TGII-mediated formation of isopeptides has been implicated to play a role in a variety of cellular processes, the physiological function of TGII remains unclear. In addition to this Tease activity, TGII is a guanosine triphosphatase (GTPase) which binds and hydrolyzes GTP It is now well recognized that the GTPase action of TGII regulates a receptor-mediated transmembrane signaling, functioning as a signal transducer of the receptor. This TGII function signifies that TGII is a new class of GTP-binding regulatory protein (G-protein) that differs from "Classical" heterotrimeric G-proteins. Regulation of enzyme is an important biological process for maintaining cell integrity. This review summarizes the recent development in regulation of TGII that may help for the better understanding of this unique enzyme. Since activation and inactivation of GTPase of TGII are similar to the heterotrimeric G-proteins, the regulation of heterotrimeric G-protein in the transmembrane signaling is also discussed.

• Biomolecules & Therapeutics
• /
• v.15 no.2
• /
• pp.78-82
• /
• 2007

The proto-oncogene protein DEK is a nuclear binding phosphoprotein that has been associated with various human diseases including leukemia. Histone acetylation is an important post-translational modification which plays important role in transcriptional regulation. Auto-acetylation of histone acetyltransferase PCAF results in increment of its HAT activity and facilitation of its nuclear localization. In this study, we report that DEK inhibits PCAF auto-acetylation through direct interaction. The C-terminal acidic domains of DEK are responsible for the interaction with PCAF. Using confocal microscopy, we have shown that nuclear localization of PCAF is severely inhibited by DEK. Taken together, our results suggest that DEK may be involved in various cellular signal transduction pathways accommodated by PCAF through the regulation of PCAF auto-acetylation.

• Journal of Astronomy and Space Sciences
• /
• v.12 no.1
• /
• pp.54-65
• /
• 1995

We present a design study for a remote sensing camera system which can be operated in multi-channel mode simultaneously with several bandpass filters. The camera control electronics is based on the multiplexed driving concept, which can provide a variety of flexibility for system control parameters and its individual optimisation. The design can also be applied to any system with linear sensors or frame sensors according to its functional requirements. The system design parameters have been examined, including modification of driving waveforms for different types of sensors, waveforms for low-nosie readout circuit in analog chain, and synchronisation with other signal processing.

• Earthquakes and Structures
• /
• v.15 no.3
• /
• pp.263-273
• /
• 2018

Operational modal analysis is being widely used in aerospace, mechanical and civil engineering. Common research fields include optimal design and rehabilitation under dynamic loads, structural health monitoring, modification and control of dynamic response and analytical model updating. In many practical cases, influence of noise contamination in the recorded data makes it difficult to identify the modal parameters accurately. In this paper, an improved frequency domain method called Enhanced Least Square Complex Frequency (eLSCF) is developed to extract modal parameters from noisy recorded data. The proposed method makes the use of pre-defined approximate mode shape vectors to refine the cross-power spectral density matrix and extract fundamental frequency for the mode of interest. The efficiency of the proposed method is illustrated using an example five story shear frame loaded by random excitation and different noise signals.

• The Journal of the Acoustical Society of Korea
• /
• v.20 no.4E
• /
• pp.24-30
• /
• 2001

This paper describes a fast harmonic estimation, referred to as Delta Adjustment (DA), using a low resolution pitch. The presented DA method is based on modification of the Generalized Dual Excitation (GDE) technique[1] which was proposed to improve speech enhancement performance. We introduce the GDE technique and modify it to be suitable for low bit rate harmonic coding that uses only an integer pitch estimate. Unlike the GDE, the DA matches a frequency-warped version of the original spectrum that conforms to a fixed pitch at all harmonic bands. In addition, complexity and performance of the presented method are described in comparison with those of the conventional Fractional Pitch (FP) based harmonic estimation. Experimental results showed that the DA algorithm significantly reduces the complexity of the FP method while maintaining the performance.

• Journal of Magnetics
• /
• v.11 no.4
• /
• pp.189-194
• /
• 2006

The recent development of bio-conjugated magnetic nanoparticles offers many opportunities for applications in the field of biomedicine. In particular, the use of magnetic nanoparticles for biosensing has generated widespread research efforts following the progress of various magnetic field sensors. Here we demonstrate substrate-free biosensing approaches based on the Brownian rotation of ferromagnetic nanoparticles suspended in liquids. The signal transduction is through the measurement of the magnetic ac susceptibility as a function of frequency, whose peak position changes due to the modification of the hydrodynamic radius of bio-conjugated magnetic nanoparticles upon binding to target bio-molecules. The advantage of this approach includes its relative simplicity and integrity compared to methods that use substrate-based stray-field detectors.

• Journal of Korea Society of Industrial Information Systems
• /
• v.17 no.5
• /
• pp.37-42
• /
• 2012

Audio steganography is quite similar to the procedure of modifying the least significant bit(LSB) of image media files. The most widely used technique today is hiding of secret messages into a digitized audio signal. In this paper, I propose a new method for hiding messages from attackers, high data inserting rate is achieved. In other words, based on the LSB hiding method and digitized to change the bit position of a secret message, an encrypted stego medium sent to the destination in safe way.

• Proceedings of the Acoustical Society of Korea Conference
• /
• 1998.08a
• /
• pp.87-92
• /
• 1998

In general, the synthesis unit database was constructed by recording isolated word. In that case, each boundary of word has typical prosodic pattern like a falling intonation or preboundary lengthening. To get natural synthetic speech using these kinds of database, we must artificially distort original speech. However, that artificial process rather resulted in unnatural, unintelligible synthetic speech due to the excessive prosodic modification on speech signal. To overcome these problems, we gathered thousands of sentences for synthesis database. To make a phone level synthesis unit, we trained speech recognizer with the recorded speech, and then segmented phone boundaries automatically. In addition, we used laryngo graph for the epoch detection. From the automatically generated synthesis database, we chose the best phone and directly concatenated it without any prosody processing. To select the best phone among multiple phone candidates, we used prosodic information such as break strength of word boundaries, phonetic contexts, cepstrum, pitch, energy, and phone duration. From the pilot test, we obtained some positive results.

• 한국정보통신설비학회:학술대회논문집
• /
• 2006.08a
• /
• pp.219-222
• /
• 2006

In this paper we present a cryptanalysis of the generalized patchwork algorithm under the assumption that the attacker possesses only a single copy of the watermarked audio. In the scheme, watermark is inserted by modifying randomly chosen DCT values in each block of the original audio. Towards the attack we first fit low degree polynomials (which minimize the mean square error) on the data available from each block of the watermarked content. Then we replace the corresponding DCT data of the at-tacked audio by the available data from the polynomials to construct an attacked audio. The technique nullifies the modification achieved during watermark embedding. Experimental results show that recovery of the watermark becomes difficult after the attack.