• Journal of Biosystems Engineering
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• 제23권1호
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• pp.67-74
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• 1998

A nondestructive quality inspection technique using acoustic impulse response method was developed for eggshell inspection. An experimental system was built to generate the impact force, to measure the response signal and to analyze the frequency spectrum. This system includes an impulse generating unit, an egg holding seal a microphone with preamplifier, and a DSP board installed on Personal Computer. A simple algorithm .was developed for crack detection. Using the developed system with algorithm, crack detection ability was evaluated and the error rate to estimate the normal egg as cracked was found to be 4% and the error rate to estimate the cracked egg as normal was also found to be 4%. This system could be adopted in industry with some modification.

• 대한음성학회지:말소리
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• 제64호
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• pp.121-135
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• 2007

Speech signal is distorted by channel characteristics or additive noise and then the performances of speaker or speech recognition are severely degraded. To cope with the noise problem, we propose a modified HMM decoder algorithm using SNR-based observation confidence, which was successfully applied for GMM in speaker identification task. The modification is done by weighting observation probabilities with reliability values obtained from SNR. Also, we apply PSO (particle swarm optimization) method to the confidence function for maximizing the speaker identification performance. To evaluate our proposed method, we used the ETRI database for speaker recognition. The experimental results showed that the performance was definitely enhanced with the modified HMM decoder algorithm.

• BMB Reports
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• 제34권2호
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• pp.95-101
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• 2001

Tissue transglutaminase (TGII, $G{\alpha}h$) belongs to a family of enzymes which catalyze post-translational modification of proteins by forming isopeptides via $Ca^{2+}$-dependent reaction. Although TGII-mediated formation of isopeptides has been implicated to play a role in a variety of cellular processes, the physiological function of TGII remains unclear. In addition to this Tease activity, TGII is a guanosine triphosphatase (GTPase) which binds and hydrolyzes GTP It is now well recognized that the GTPase action of TGII regulates a receptor-mediated transmembrane signaling, functioning as a signal transducer of the receptor. This TGII function signifies that TGII is a new class of GTP-binding regulatory protein (G-protein) that differs from "Classical" heterotrimeric G-proteins. Regulation of enzyme is an important biological process for maintaining cell integrity. This review summarizes the recent development in regulation of TGII that may help for the better understanding of this unique enzyme. Since activation and inactivation of GTPase of TGII are similar to the heterotrimeric G-proteins, the regulation of heterotrimeric G-protein in the transmembrane signaling is also discussed.

• Biomolecules & Therapeutics
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• 제15권2호
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• pp.78-82
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• 2007

The proto-oncogene protein DEK is a nuclear binding phosphoprotein that has been associated with various human diseases including leukemia. Histone acetylation is an important post-translational modification which plays important role in transcriptional regulation. Auto-acetylation of histone acetyltransferase PCAF results in increment of its HAT activity and facilitation of its nuclear localization. In this study, we report that DEK inhibits PCAF auto-acetylation through direct interaction. The C-terminal acidic domains of DEK are responsible for the interaction with PCAF. Using confocal microscopy, we have shown that nuclear localization of PCAF is severely inhibited by DEK. Taken together, our results suggest that DEK may be involved in various cellular signal transduction pathways accommodated by PCAF through the regulation of PCAF auto-acetylation.

• Journal of Astronomy and Space Sciences
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• 제12권1호
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• pp.54-65
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• 1995

We present a design study for a remote sensing camera system which can be operated in multi-channel mode simultaneously with several bandpass filters. The camera control electronics is based on the multiplexed driving concept, which can provide a variety of flexibility for system control parameters and its individual optimisation. The design can also be applied to any system with linear sensors or frame sensors according to its functional requirements. The system design parameters have been examined, including modification of driving waveforms for different types of sensors, waveforms for low-nosie readout circuit in analog chain, and synchronisation with other signal processing.

• Earthquakes and Structures
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• 제15권3호
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• pp.263-273
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• 2018

Operational modal analysis is being widely used in aerospace, mechanical and civil engineering. Common research fields include optimal design and rehabilitation under dynamic loads, structural health monitoring, modification and control of dynamic response and analytical model updating. In many practical cases, influence of noise contamination in the recorded data makes it difficult to identify the modal parameters accurately. In this paper, an improved frequency domain method called Enhanced Least Square Complex Frequency (eLSCF) is developed to extract modal parameters from noisy recorded data. The proposed method makes the use of pre-defined approximate mode shape vectors to refine the cross-power spectral density matrix and extract fundamental frequency for the mode of interest. The efficiency of the proposed method is illustrated using an example five story shear frame loaded by random excitation and different noise signals.

• The Journal of the Acoustical Society of Korea
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• 제20권4E호
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• pp.24-30
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• 2001

This paper describes a fast harmonic estimation, referred to as Delta Adjustment (DA), using a low resolution pitch. The presented DA method is based on modification of the Generalized Dual Excitation (GDE) technique[1] which was proposed to improve speech enhancement performance. We introduce the GDE technique and modify it to be suitable for low bit rate harmonic coding that uses only an integer pitch estimate. Unlike the GDE, the DA matches a frequency-warped version of the original spectrum that conforms to a fixed pitch at all harmonic bands. In addition, complexity and performance of the presented method are described in comparison with those of the conventional Fractional Pitch (FP) based harmonic estimation. Experimental results showed that the DA algorithm significantly reduces the complexity of the FP method while maintaining the performance.

• Journal of Magnetics
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• 제11권4호
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• pp.189-194
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• 2006

The recent development of bio-conjugated magnetic nanoparticles offers many opportunities for applications in the field of biomedicine. In particular, the use of magnetic nanoparticles for biosensing has generated widespread research efforts following the progress of various magnetic field sensors. Here we demonstrate substrate-free biosensing approaches based on the Brownian rotation of ferromagnetic nanoparticles suspended in liquids. The signal transduction is through the measurement of the magnetic ac susceptibility as a function of frequency, whose peak position changes due to the modification of the hydrodynamic radius of bio-conjugated magnetic nanoparticles upon binding to target bio-molecules. The advantage of this approach includes its relative simplicity and integrity compared to methods that use substrate-based stray-field detectors.

• 한국산업정보학회논문지
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• 제17권5호
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• pp.37-42
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• 2012

오디오 스테가노그래피는 오디오 매체(신호)에 암호화된 비밀 메시지를 은닉하여 전송하는 일반적이고, 폭넓게 이용되는 통신기법이다. 인간은 청각시스템의 지각능력의 한계 때문에 커버 오디오 파일과 스테고 오디오 파일의 지각품질(perceptual quality) 차이는 없다. 또한 공격자로부터의 안전성과 견고성 측면에서 LSB 기법은 디지털화된 오디오 신호에 메시지를 삽입하는 효율적이고, 경제적인 방법으로 널리 이용되고 있다. 이 논문에서는 LSB 기법을 기반으로 하고, 디지털화된 비밀 메시지의 비트별 위치를 변경하고, 암호화한 후 커버 오디오 매체에 은닉하는 개선된 방법을 제시한다.

• 한국음향학회:학술대회논문집
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• 한국음향학회 1998년도 제15회 음성통신 및 신호처리 워크샵(KSCSP 98 15권1호)
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• pp.87-92
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• 1998

In general, the synthesis unit database was constructed by recording isolated word. In that case, each boundary of word has typical prosodic pattern like a falling intonation or preboundary lengthening. To get natural synthetic speech using these kinds of database, we must artificially distort original speech. However, that artificial process rather resulted in unnatural, unintelligible synthetic speech due to the excessive prosodic modification on speech signal. To overcome these problems, we gathered thousands of sentences for synthesis database. To make a phone level synthesis unit, we trained speech recognizer with the recorded speech, and then segmented phone boundaries automatically. In addition, we used laryngo graph for the epoch detection. From the automatically generated synthesis database, we chose the best phone and directly concatenated it without any prosody processing. To select the best phone among multiple phone candidates, we used prosodic information such as break strength of word boundaries, phonetic contexts, cepstrum, pitch, energy, and phone duration. From the pilot test, we obtained some positive results.