• Title/Summary/Keyword: Signal Intensity

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Uncertainty Minimization in Quantitative Electron Spin Resonance Measurement: Considerations on Sampling Geometry and Signal Processing

  • Park, Sangeon;Shim, Jeong Hyun;Kim, Kiwoong;Jeong, Keunhong;Song, Nam Woong
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.2
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    • pp.53-58
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    • 2020
  • Free radicals including reactive oxygen species (ROS) are important chemicals in the research area of biology, pharmaceutical, medical, and environmental science as well as human health risk assessment as they are highly involved in diverse metabolism and toxicity mechanisms through chemical reactions with various components of living bodies. Electron spin resonance (ESR) spectroscopy is a powerful tool for detecting and quantifying those radicals in biological environments. In this work we observed the ESR signal of 2,2,6,6-Tetra-methyl piperidine 1-oxyl (TEMPO) in aqueous solution at various concentrations to estimate the uncertainty factors arising from the experimental conditions and signal treatment methods. As the sample position highly influences the signal intensity, dual ESR tube geometry (consists of a detachable sample tube and a position fixed external tube) was adopted. This type of measurement geometry allowed to get the relative uncertainty of signal intensity lower than 1% when triple measurements are averaged. Linear dependence of signal intensity on the TEMPO concentration, which is required for the quantification of unknown sample, could be obtained over a concentration range of ~103 by optimizing the signal treatment method depending on the concentration range.

Anthracofibrosis Mimicking Lung Cancer on CT: MR Imaging Findings (CT상 폐암과 유사하게 보이는 기관지 탄분 섬유화증의 자기공명영상 소견)

  • 류대식;이덕희;정승문;최수정;박성빈;박만수;강길현
    • Investigative Magnetic Resonance Imaging
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    • v.5 no.1
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    • pp.18-23
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    • 2001
  • Purpose : To describe the MRI findings in the bronchial anthracofibrosis mimicking lung cancer on CT examination. Materials and methods : Ten patients, who showed CT findings mimicking lung cancer, were selected among fifty patients of bronchial anthracofibrosis proven by bronchoscopic biopsy, consisting of two men and eight women, ranging in age from 58 to 79 years old faverage age, 68 years old). CT scan and MRI were performed in all patients (n=10). Percutaneous lung biopsy on mass was performed in one patient. MRI findings were analyzed with the emphasis on the signal intensity of the mass (n=4), collapsed lung (n=4) and Iymph node (n=10) on axial T1 and T2-weighted images by two radiologists in consensus. No contrast enhancement was used in all cases. Results : CT scan revealed mass (n=4), atelectasis with obstructive pneumonia(n=4) and bronchial wall thickening(n=2). All patients showed enlarged medistinal Iymph nodes(n=10). The mass showed low signal intensity on T1WI and T2WI (n =4). The collapsed lung in patients with atelectasis indicated intermediate signal intensity on T1WI and low signal intensity on T2WI (n= 4). Nine patients showed low sisnal intensity of Iymph node on T1WI and T2WI, except one patient who showed central high signal intensity with peripheral rim of low signal intensity in right lower paratracheal llmph node on T2WI. Conclusion : Low signal intensity of a mass, collapsed lung, and lymph nodes on T2WI in anthracofibrosis patients may be helpful in differentiation of the lesion from lung cancer.

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Magnetic resonance images of ameloblastoma

  • Kim Jae-Duk;Kim Jin-Soo
    • Imaging Science in Dentistry
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    • v.35 no.4
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    • pp.207-213
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    • 2005
  • Purpose: To classify and describe the characteristic features of MRI of some ameloblastoma variants. Materials and Methods: The MR images, CT images, and panoramic radiographs in 5 cases were retrospectively examined as follows. First, the contents of ameloblastomas were devided into two portions of either solid or cystic components on the basis of MR signal intensities. The signal intensity within the solid or cystic portions was classified as homogeneous or heterogeneous. Next, the characteristic internal feature of the lesion on T1W1 or T2WI was described. The signal intensities were classified into low, intermediate, slightly high, high, and strong high signal intensity. Results: Unicystic lesion showed homogeneous high signal intensity (SI) on T2W2 and the rim enhancement of the surrounding area including the mural nodule and the thick wall except the central portion on Gd- T1W1. Solid type revealed heterogeneous and high SI area with strong high SI area on T2W2. On Gd- T1W1, the area corresponding to the low signal spot on T1W1 and the strong high signal spot on T2W1 showed low SI. Hybrid type showed slightly enhanced capsular structures and low SI for the round bony septa and the areas connecting the mixed and cystic lesions on T2Wl and Gd-T1W1. Conclusion: MRI could easily assess the relationship between the mixed and cystic findings in ameloblastoma.

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The Detection of Intracranial Calcification by MR : Experimental Model (실험적 모델을 이용한 자기공명영상에서 석회화의 인지)

  • 박승진
    • Progress in Medical Physics
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    • v.5 no.1
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    • pp.3-12
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    • 1994
  • Purporse : It is known that detection of calcification by MRI is difficulty in intracranial calcified lesions, but author tried to evaluate the signal intensity image of calcification by MR with experimental model. Subjects & Methods : Author analyzed and compared with values of calcium carbonate and hydroxyapatite phantoms by each concentration (10, 20, 30, 40, 50%) and size(1-10mm), measured ROI attenuating from CT and MRI(TlWI & T2WI). Results : The high concentration of calcium carbonate is, the lower the signal intensity of calcium carbonate phantom is both T1 & T2WI. For concentration of Hydroxyapatite of up to 30% by weight the signal intensity on standard T1 weighted images increased but subsequently decreased. Hyperintensity does not preclude calcification as a cause of the signal alteration-an observation that all radiologists interpreting MR images need to be aware of. Conclusion: The signal intensity of intracranial calcification is various on MR imaging in concerning with components, concentration, & size of calcification, and especially high signal intensity of intracranial calcification noted differencial diagnosis.

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A study on the Relationship between the Size of Defect and the Intensity of Eddy Current Signal in Heat Exchanging Tube made of STS 304. (Stainless강(鋼) 전열관(傳熱管)에 있어서 과전류(過電流) 신호강도(信號强度)와 결함(缺陷)크기와의 관계에 관한 연구(硏究))

  • Han, E.K.;Eom, H.S.;Park, I.G.;Choi, M.S.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.6 no.2
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    • pp.7-16
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    • 1987
  • Eddy Current Examination is expected as the effective technique for nondestructive inspection of steam generator and various kinds of heat exchanging tubes made of STS - 304. In Case of E. C. T, a study on the various factors which have an effect on coil impedance is very important to the sensitivity of defect detection and the ratio of signal to noise. Therefore, this study analyzed coil impedance by means of the variational principle, the minimized theory of energy functional and the application of Finite Element Method. Really by using E. C. T, the relationship between the size of defects and the intensity of Eddy Current Signals can be obtained. Signal intensity becomes maximum at certain frequency. This frequency is affected by the characteristics and the position of signal sources.

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Measurement and Analysis of Knock Using a Microphone Sensor in a S.I. Engine (전기점화기관에서 마이크로폰 센서를 이용한 노킹 측정 및 분석)

  • 황승환;이종화;임진수
    • Transactions of the Korean Society of Automotive Engineers
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    • v.5 no.3
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    • pp.202-208
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    • 1997
  • The knocking is one of major parameters to improve engine performance in a spark ignition engine. Many researches have been carried out to identify them using cylinder pressure, vibration signal and so on. In the present study, measurement and analysis was conducted to set up the criteria of knock occurrence by using microphone signal. Cylinder pressure was measured for the reference signal of knocking. It has been observed that resonance frequencies of pressure wave are nearly independent of engine operating conditions such as engine speed, air fuel ratio, load and octane number of fuel within to limited experimental conditions. SDBP(sum of different band-pass data) method using resonance frequency of knock was proposed for estimating knock intensity. SDBP method is superior to identify knock occurrence and its intensity in case of sound pressure measurement.

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Error Intensity Function Models for ML Estimation of Signal Parameter, Part I : Model Derivation (신호 파라미터의 ML 추정기법에 대한 에러 밀도 함수 모델에 관한 연구 I : 모델 정립)

  • Joong Kyu Kim
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.30B no.12
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    • pp.1-11
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    • 1993
  • This paper concentrates on models useful for analyzing the error performance of ML(Maximum Likelihood) estimators of a single unknown signal parameter: that is the error intensity model. We first develop the point process representation for the estimation error and the conditional distribution of the estimator as well as the distribution of error candidate point process. Then the error intensity function is defined as the probability dessity of the estimate and the general form of the error intensity function is derived. We then develop several intensity models depending on the way we choose the candidate error locations. For each case, we compute the explicit form of the intensity function and discuss the trade-off among models as well as the extendability to the case of multiple parameter estimation.

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Measurement of Fluorescence Signal Strength of NO Particle Using ICCD (ICCD를 이용한 NO입자의 형광신호강도 측정)

  • 전용우;박원주;이광식;이홍식
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.15 no.4
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    • pp.23-30
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    • 2001
  • In this paper, the discharge image of NO particles wire-cylinder type electrode in the discharge reactor where AC dielectric barrier type corona discharge occurred and horizontal and vertical signal intensity at each flourescence emission during discharge and the horizontal and vertical signal strength of NO particles at flourescence emission wavelength band[236[nm], 247[nm]], were measured were measured by ICCD Camera. In addition discharge images and signal intensities in accordance with discharge time were measured to figure out the discharge mechanism. It was found that the strongest horizontal and vertical signal intensity of NO particles were observed at 247[nm] band, but no big difference in the horizontal and vertical signal intensity in accordance with discharge time was seen. In particular, the phenomenon image occuring inside the discharge reactor and wavelength ware able to be carried based on the measured data.

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Comparative Study of a Multi-Channel Coils of Magnetic Resonance Imaging(MRI) Signal Intensities under Identical Parameters (동일한 조건의 자기공명검사에서 코일의 채널수 변화에 따른 신호강도의 평가)

  • Son, Soon-Yong
    • The Journal of the Korea Contents Association
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    • v.19 no.6
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    • pp.418-423
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    • 2019
  • The purpose of this study was to determine how the different number of channels of coils were related in the perceived signal intensity under identical parameters and area. Dedicated knee phantoms were scanned consecutively using both of the 16-channel and 8-channel knee coils. The T1 weighted and T2 weighted sequences were acquired using both coils to compare the signal intensities according to the number of channels. As a result, the 16-channel knee coils outperformed the 8-channel knee coils and the signal intensity was significantly increased in both of the T1 and T2 weighted images with the 16-channel coil. In conclusion, it is considered that better signal intensities and more clinical utility can be provided, when coils with more number of channels are used rather than using the coils with smaller number of channels.

RELATIVE SIGNAL INTENSITY OF RETRODISCAL TISSUE IN MRI, AND SYNOVIAL FLUID CONCENTRATION OF INTERLEUKIN-6, MMP-2 AND MMP-9 IN TEMPOROMANDIBULAR JOINT DISORDER (악관절질환에서 MRI 상 관절원판 후조직의 상대적 신호강도와 관절액의 Interleukin-6, MMP-2 및 MMP-9 농도)

  • Lee, Sang-Hwa;Choie, Mok-Kyun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.5
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    • pp.399-408
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    • 2005
  • In the progression of the Temporomandibular Joint Disorder(TMD), not only deformation and perforation of disc occur. But also fibrotic adhesion and inflammatory changes to the retrodiscal tissue can be seen in addition to the condylar degenerative change (e.g. osteoarthritis). However, the correct diagnosis,?planning for appropriate treatment, and prediction of prognosis are limited, because there are no means to stage the progression of the disorder. In this study relative signal intensity of retrodiscal tissue in MRI and the synovial fluid concentration of matrix metalloproteinase-2 (MMP-2), MMP-9, and Interleukin-6(IL-6) in the 23 temporomandibular joints(TMJ), from 17 patients with TMD were evaluated as a possible diagnostic marker. The relative signal intensity of retrodiscal tissue was referenced to brain gray matter with same region of interest(ROI) size. The concentrations of MMP-2, MMP-9, and IL-6 were evaluated by Enzyme Linked Immunosorbent Assay (ELISA). The collected data were compared with condylar degenerative change, joint effusion and disc position observed in MRI. The relative signal intensity of the retrodiscal tissue was increased significantly when degenerative changes were present. In addition, there was significantly high signal intensity in the presence of a disc displaced without reduction. The concentration of IL-6 was significantly increased when condylar degenerative change was no observed. And there were no changes in the levels of IL-6 according to disc position and joint effusion measurement. Moreover, there were no significant relevance between the concentration of total MMP-2 and active MMP-9 in synovial fluid, relative to degenerative changes in the mandibular condyle, to joint effusion, and to disc position observed on MRI images. In conclusion, the relative signal intensity of the retrodiscal tissue can be regarded as a mean of diagnosing the procession of TMD in a non-invasive manner. But more additional studies are required for the levels of MMP-2. MMP-9, and IL-6 to determine their potentials as a diagnostic marker for TMD.