• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.05a
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• pp.14-23
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• 2002

Development of oligodendrocytes and the generation of myelin internodes within the spinal cord depends on regional signals derived from the notochord and axonally derived signals. Neuregulin (NRG)-1, localized in the floor plate as well as in motor and sensory neurons, is necessary for normal oligodendrocyte development. Oligodendrocytes respond to NRGs by activating members of the erbB receptor tyrosine kinase family. Here, we show that erbB2 is not necessary for the early stages of oligodendrocyte precursor development, but is essential for proligodendroblasts to differentiate into galactosylcerebroside-positive (GalC+) oligodendrocytes. In the presence of erbB2, oligodendrocyte development is normal. In the absence of erbB2 (erbB2-/-), however, oligodendrocyte development is halted at the proligodendroblast stage with a >10-fold reduction in the number of GalC+ oligodendrocytes. ErbB2 appears to function in the transition of proligodendroblast to oligodendrocyte by transducing a terminal differentiation signal, since there is no evidence of increased oligodendrocyte death in the absence of erbB2. Furthermore, known survival signals for oligodendrocytes increase oligodendrocyte numbers in the presence of erbB2, but fail to do so in the absence of erbB2. Of the erbB2-/- oligodendrocytes that do differentiate, all fail to ensheath neurites. These data suggest that erbB2 is required for the terminal differentiation of oligodendrocytes and for development of myelin.

• IE interfaces
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• v.16 no.spc
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• pp.111-115
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• 2003

Railroad system is consisted of resources of rail track, signal system, and vehicles. Railway operation must use these limited resources and maximize resource utilization. Line capacity(number of trains throughput/day) is determined by such as parameters, line utilization rate($\alpha$), dummy rate for the break-through hour($\beta$), and dummy rate for the number of rail track intervals($\delta$). Line capacity simulation(LCS) determined the line capacity through simulation given $\alpha$, $\beta$, and $\delta$. This paper deals with the development of parameter evaluation simulation(PES). PES presents the decision maker with the relationship of line capacity and measurement of robustness for various scenarios in different parameters and then the decision maker can determine the appropriate parameters.

• Journal of the Ergonomics Society of Korea
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• v.19 no.3
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• pp.13-21
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• 2000

Men perceive and react around him through the five senses. Also men give rise to the human sensibility and maintain his emotion. This study doesn't limit working environment to VDT environment, but considers the universal working environment acquiring information by eyesight stimulation. In case of forming an abnormal veiling reflection we consider the form ; a vertical(25%, 50%, 75%)and a horizontal(25%, 50%, 75%). The results from the subjective evaluation are analyzed by SD(Semantic Differentical methodology)of 5 point scale for visibility and nuisance when an abnormal veiling reflection forms on target. In addition, the results of the objective evaluation are suggested by measuring and analyzing EEG of bio-signal for visual sensitivity. The results of this study can apply to basic data which create a guideline of a visual operation. In particular, it can be designed as an illumination environment concerning an ergonomic factor on visual operations, mental stress such as a visual inspection operation, visual information search operation, etc. As a result, we can expect to reduce the visual nuisance and contribute to the improvement of the performance and the uplift of the competitive power.

• Journal of Institute of Control, Robotics and Systems
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• v.16 no.5
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• pp.440-445
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• 2010

This paper proposes a single accelerometer sensor control algorithm to mobile inverted pendulum, generally called 'Segway', and evaluates the performance of this system comparing to the conventional ones. The commercialized 'Prototype Segway-PT' is initially considered as a next-generation transport vehicle. However, this robot is operated by three gyroscopes and two accelerometers to control the posture and speed, and it requires the complex signal processing for fusing the two sets of data. As the result of this, the growth rate of market size of 'Segway' is slow because of its high price mainly. In this paper, the mobile inverted pendulum is operated by a single accelerometer to simplify the control system to lower the price. Low pass filter is one of the good sensors to reducing the variation of an accelerometer, but it has time delay. This time delay disturbs real-time mobile inverted pendulum control. Like this, other various algorithms are used for this system, but each one has its own weak point. So this paper proposes a new filtering method, median filter and EKF. Median filter is used to image processing to reject impulse elements like salt and pepper noise. As the major performance evaluation parameter for the accelerometer, the high-frequency to low frequency ratio from FFT (Fast Fourier Transform) is used. Effectiveness of the proposed algorithms has been verified through the real experiments and the results are demonstrated.

• The Journal of the Acoustical Society of Korea
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• v.31 no.5
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• pp.317-331
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• 2012

In this paper, we develop a multichannel blind source separation algorithm based on a beamspace transform and the multichannel non-negative matrix factorization (NMF) method. The NMF algorithm is a famous algorithm which is used to solve the source separation problems. In this paper, we consider a beamspace-time-frequency domain data model for multichannel NMF method, and enhance the conventional method using a beamspace transform. Our decomposition algorithm is applied to audio source separation, using a dataset from the international Signal Separation Evaluation Campaign 2010 (SiSEC 2010) for evaluation.

• Nuclear Engineering and Technology
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• v.52 no.10
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• pp.2328-2333
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• 2020

The filter technique was applied to noise images, as noise is the significant factor that cause poor image quality due to lower photon counting. The purpose of this study is to confirm that image quality can be improved using the median modified Wiener filter (MMWF) technique; this is achieved via a National Electrical Manufacturers Association International Electrotechnical Commission body phantom with four large spheres that are filled with the ^99mTc radioisotope when evaluating the image quality. Conventional filters such as Wiener, Gaussian, and median filters were designed, and signal to noise ratio, coefficient of variation, and contrast to noise ratio were used as the evaluation parameters. The improvement in the image quality was in the following order, from the least to the highest improvement, in all cases: Wiener filter, Gaussian filter, median filter, and the MMWF technique. The results show that the image quality was improved from 20.6 to 65.5%, 7.4-40.3%, and 12.7-44.7% for the SNR, COV, and CNR values, respectively, when using the MMWF technique, compared with the use of conventional filters. In conclusion, our results demonstrated that the MMWF technique is useful for reducing the noise distribution in gamma camera images.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.10A
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• pp.1473-1479
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• 2000

This paper presents the performance evaluation of an adaptive QAM scheme under flat and frequency selective fading channels for indoor wireless communication systems. The QAM modulation is combined with differential encoding and the demodulation process is carried out noncoherently. The adaptation is performed by varying the modulation level of QAM, depending upon received signal strength. The adaptation mechanism allows a 2- or 3-bit increase or decrease at a time, if the channel condition is considered to be significantly good or bad. Simulation results show that the average number of bits per symbol (ABPS) for each symbol block transmitted over a flat fading channel is higher than 5.0 and the BER performance is better than 10^-4 for a SNR value higher than 30 dB. For frequency selective fading channels, an oversampling technique in the receiver was employed. The BER performance obtained for frequency selective fading channels is better than 10^-4 with a SNR value of 40 dB and ABPS is found to be approximately 5.5. Therefore, this scheme is very useful in that it provides both very high bandwidth efficiency and acceptable performance with moderate SNR values over flat and frequency selective fading channels. In addition, this scheme provides reduced receiver complexity by way of noncoherent detection.

• Journal of Korean Society of Transportation
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• v.26 no.4
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• pp.161-172
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• 2008

The level of service (LOS) evaluation method of the Highway Capacity Manual (HCM) is limited to intersections with pre-timed signal operation, while advanced real-time traffic control systems have been expending in the field. This paper proposes a preliminary framework for LOS analysis at isolated intersections controlled by COSMOS, the real-time traffic control systems robustly utilizing the degree of saturation as basic inputs. The proposed LOS evaluation framework was devised with a pilot model developed to estimate the average cycle length and green times of COSMOS. The validation test showed that the proposed framework was able to accurately project the LOS, which was separately evaluated based upon field data.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.818-823
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• 2005

Creep damage is one of the mosl important characteristics for the stability of high temperature structures such as huge energy converting facilities. Creep failure of Type 316LN stainless steel is highly correlated to generation and growth of the voids. In this paper, in order to investigate the correlation of creep rupture time and ultrasonic parameters (group velocity, angular velocity), creep-damaged Type 316LN specimens and measurements for the ultrasonic parameters were made. However, bi-directional measurements were applied along the load direction and the perpendicular direction to the load line by means of the contact type probe of which the central frequencies are 10MHz, 15MHz and 20MHz. Analyzing the angular velocities of the ultrasonic signals obtained from the load direction, it was confirmed that the angular velocities were declined as the creep time passed when 15MHz and 20MHz probes were used. Also, the group velocities were declined for all three frequencies as the creep time increased. Thus, positive feasibility for the creep damage evaluation by means of the angular and group velocities was confirmed. Moreover, result of analysis for the ultrasonic signal which was obtained from the perpendicular direction upon the angular and group velocities indicated little variation for both of the angular and group velocities. Therefore, the creep damage is likely to represent anisotropic itself.

• Korean Journal of Metals and Materials
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• v.46 no.6
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• pp.390-401
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• 2008

The objective of this study is to evaluate various machining characteristics of AlN-hBN machinable ceramics in micro end-milling process for its further application. First, AlN based machinable ceramics with hBN contents in the range of 10 to 20vol% were prepared by hot-pressing. Material properties of the composites, such as relative density, Vickers hardness, flexural strength, Young's modulus and fracture toughness were measured and compared. Then, micro end-milling experiments were performed to fabricate micro channels using prepared system. During the process, cutting forces, vibrations and AE signals were measured and analyzed using applied sensor system. Machined micro channel shapes and surface roughness were measured using 3D non-contact type surface profiler. From the experimental results, it can be observed that the cutting forces, vibrations and AE signal amplitudes decreased with increasing hBN contents. Also, measured surface roughness and profiles were improved with increasing hBN contents. As a result of this study, optimum machining conditions can be determined to fabricate desired products with AlN-hBN machinable ceramics based on the experimental results of this research.