• Title/Summary/Keyword: Sign Reversal

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A COMPARATIVE STUDY ON THE VITAL SIGN AND BEHAVIOR APPEARANCE DEPENDING ON THE ROUTE OF FLUMAZENIL ADMINISTRATION IN CONSCIOUS SEDATION BY MIDAZOLAM (Midazolam을 이용한 의식진정시 flumazenil의 투여경로에 따른 생징후 및 행동양상의 비교 연구)

  • Kim, Hyun-Sik;Lee, Chang-Seop;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.2
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    • pp.159-167
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    • 2002
  • The purpose of this study was to evaluate the efficacy and safety depending on the route of flumazenil, as an antagonist against midazolam. The subjects of this study were 15 volunteers of $22{\sim}24$ years old. They were sedated with midazolam 0.2mg/Kg intranasal spray, and then 40 minutes after midazolam administration, they were given flumazenil 0.2mg intranasal spray for their reversal. For evaluation of the efficacy and safety of intranasal spray for flumazenil, they were monitored with pulse-oxymeter(Nellcor symphony N-3000, Nellcor Puritan CO. USA) and electric sphygmomanometer (Heartcare 200, National CO. Japan), and were assessed themselves using visual analogue scale(VAS) for tranquilization, sleep, fatigue and attitude. All of these subjects were reduced completely without any undesired situations. The results from this study can be summarized as follows ; 1. Nasaly administered flumazenil using spray device produced much more rapid reduction than intravenously administered flumazenil, but soon after fell in more deep sedated state than intravenously administered flumazenil. 2. There were no considerable side effects or bad influence on vital signs of both nasaly administered flumazenil and intravenously administered flumazenil. These results suggested that the flumazenil administered nasaly using spray device for reversal, we could treat patients safely and effectively under conscious sedation using midazolam administration. But, We will have to research about its optimal dosages for flumazenil, used as intranasal spray for reversal agents against the midazolam by evaluating the blood plasma concentration of midazolam and flumazenil.

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EFFECT OF ADMINSTRATION METHOD OF FLUMAZENIL ON THE PLASMA CONCENTRATION AND THE REVERSAL OF SEDATION INDUCED BY MIDAZOLAM (Flumazenil의 투여 방법에 따른 혈장내 농도와 midazolam에 의해 유도된 진정 상태의 환원 효과)

  • Park, Seong-Kyu;Lee, Sang-Ho;Lee, Chang-Seop;Lee, Nan-Young;Oh, You-Hyang
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.3
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    • pp.499-508
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    • 2005
  • The purpose of this study were to evaluate the effect on the reversion of sedation induced by midazolam with flumazenil and to determine the plasma concentration of flumazenil according to the method of administration. Intranasal and intravenous flumazenil were administered to sedated health volunteers aged from 23 to 25 years, in doses typical of those used clinically to induce sedation with midazolam and for reversal with flumazenil. Objective assessment for degree of sedation and vital signs, plasma concentration were made for 2 hours period. 1. Systolic and diastolic blood pressure, $SpO_2$ were not changed by adminstration of flumazenil in sedated subject with midazolam, but pulse rate was increased temporarily. 2. Flumazenil showed the reversal of the sedative effect induced by midazolam regardless of administration methods. But intravenous administration showed more effect on the degree and the duration of reversion than intranasal administration with the exception of on set time. 3. Peak plasma concentration of flumazenil administered by intranasal route reached after 2 min and that of flumazenil administered by intravenous route was 4 min. Thus uptake of flumazenil did not showed any difference in accordance with the adminstration route. 4. Administration of flumazenil resulted in the temporary increase of midazolam plasma concentration.

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Relation of CME Speed and Magnetic Helicity in the Source Region during Increasing Phase of Solar Cycle 24

  • Kim, Roksoon;Park, Sunghong;Cho, Kyungsuk
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.67.1-67.1
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    • 2016
  • We examined the relations between CME speed and properties of magnetic helicity in the source region such as helicity injection rate and total unsigned magnetic flux, which reflect the magnetic energy in the active region. For this, we selected 22 CMEs occurred during the increasing phase of solar cycle 24, which shows extremely low activities and classified them into two groups according to evolution pattern of helicity injection rate. We then compared the relations with those from previous study based on the events in solar cycle 23. As the results, we found several properties as follows: (1) Both of CME speed and helicity parameters have very small values since we only considered increasing phase; (2) among 22 CMEs, only 6 events (27%) are classified as group B, which show sign reversal of helicity injection and they follow behind of appearance of group A events. This fact is well coincide with the trend of solar cycle 23 that only group A events was observed in the first 3 years of the period; (3) as the solar activity is increasing, the CME speed and helicity parameters are also increasing. Based on the observations of solar cycle 23, the helicity parameters was still increasing in spite of decreasing solar activity after maximum period.

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The Structure and Electrical Properties of Si-ZnO n-n Heterojunctions (Si-ZnO n-n 이종접합의 구조 및 전기적 특성)

  • 이춘호;박순자
    • Journal of the Korean Ceramic Society
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    • v.23 no.1
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    • pp.44-50
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    • 1986
  • Si-ZnO n-n heterojunction diodes were prespared by r.f diode sputtering of the sintered ZnO target on n-type Si single crystal wafers and their structures and electrical properties were studied. The films were grown orientedly with the c-axis of crystallites perpendicular to the substrate surface at low r.f. powder and grown to polycrystalline films with random orientation at high r. f. powder. The crystallite size increased with the increasing substrate temperture The oriented texture films only were used to prepare the photovoltaic diodes and these didoes showed the photovoltaic effect veing positive of the ZnO side for the photons in the wavelength range of 380-1450nm. The sign reversal of phootovoltage which is the property os isotype heterojunction was not observed because of the degeneration of the ZnO films. The diode showed the forward rectification when it was biased with the ZnO side positive. The current-voltage characteristics exhibited the thermal-current type relationship J∝exp(qV/nkT) with n=1.23 at the low forward bias voltage and the tunnelling-current type relationship J∝exp($\alpha$V) where $\alpha$ was constant independent of temperature at the high forward bias voltage. The crystallite size of ZnO films were influenced largely on the photovoltaic properties of diodes ; The diodes with the films of the larger crystallites showed the poor photovoltaic properties. This reason may be cosidered that the ZnO films with the large crystallites could not grow to the electrically continuous films because the thickness of films was so thin in this experiment.

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Aorticopulmonary Window: one case report (대동맥중격결손증[수술치험 1예])

  • 최영호
    • Journal of Chest Surgery
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    • v.14 no.3
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    • pp.302-306
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    • 1981
  • Aorticopulmonary window is a rare anomaly among congenital heart disease. Various terms have been suggested including A-P window, A-P fenestration, fistula, aorticseptal defect etc. The defect lies usually between the left side of the ascending aorta and right wall of the pulmonary artery just anterior to the origin of the right main pulmonary artery. We have experienced one case of aorticopulmonary septal defect which was diagnosed as V5D with pulmonary hypertension in 1 4/12 year old, 7.2 Kg, male patient. Operation was done under the hypothermic cardiopulmonary bypass using 5t. Thomas cardioplegic solution. Vertical right ventriculotomy over the anterior wall of RVOT revealed no defect in the ventricular septum, and incision was extended up to the main pulmonary artery to find the source of massive regurgitation of blood through MPA. Finger tip compression of the aorticopulmanary window was replaced with Foley bag catheter balloon, and the $7{\times}10$ mm aorticoseptal defect located 15mm above the pulmonic valve was sutured continuously wih 3-0 nylon suture during azygos flow of cardiopulmonary cannula which was located distal to the window resulted massive air pumping systemically, and temporary reversal of pumping was tried to minimize cerebral air embolism. Remained procedure was done as usual, and pump off was smooth and uneventful. Postoperatively, patient was attacked frequent opistotonic seizure with no recovery sign mentally and p.hysically. Vital signs were gradually worsen with peripheral cyanosis and oliguria, and cardiac activity was arrested 1485 minutes after operation. Autopsy was performed to find the sutured window and massive edema of the brain.

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The Effects of the Surfactant Type on the Nanofluids Stability (계면활성제 특성에 따른 나노입자 분산안정도 향상 연구)

  • Kang, Chi-Hoon;Hong, Sung-Wook;Kang, Yong-Tae;Koo, June-Mo
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.275-280
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    • 2008
  • The effects of the surfactant type, i.e., CTAB(cationic), SDS(anionic), and GA(polymeric), on the stability of 0.1 vol.% $Al_2O_3$ nanofluids were investigated. The changes in size and zeta potential of nanoparticles in nanofluids with pH, surfactant concentration, and time were experimentally observed. The nanofluids adding CTAB, which ionizes of the same charge with the bare particle surface, was found to have the best stability regardless of the surfactant concentration, whereas those with SDS became unstable under low surfactant concentration conditions, i.e. lower than the critical micellel concentration(CMC), before the charge reversal occurred. With higher SDS concentration over CMC, they became stable. Gum Arabic, which had been used often to stabilize the nanofluids, was also tested. In result, it was found that the type and concentration of surfactants to add should be selected considering pH and the sign of the bare particle surface charge.

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Vertical Integration of Solar business and its Value Analysis: Efficiency or Flexibility (태양광 수직통합화가 사업가치에 미치는 영향: 효율성 및 유연성)

  • Kim, Kyung-Nam;Jeon, Woo-Chan;SonU, Suk-Ho
    • New & Renewable Energy
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    • v.8 no.2
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    • pp.33-43
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    • 2012
  • Why solar companies preferred vertical integration of whole value chain? Major solar companies have built internally strong vertical integration of entire PV value chain. We raise a question whether such integration increases the corporate value and whether market situation affects the result. To test these questions, we conducted multi-variant analysis where characteristic factors mainly affect the corporate value measured in terms of Tobin'Q, based on the financial and non-financial data of PV companies listed in US stock market between 2005 and 2010. We hypothesize that since integration increases the overall efficiency but decreases the flexibility to adjust to various market situation, the combined effect of the efficiency gain and the flexibility loss ultimately determines the sign of integration effect on the corporate vale. We infer that the combined effect will be influenced heavily by business cycle, as in boom market (Seller's market) the efficiency gain may be larger than the flexibility loss and vice versa in bust market. We test whether the sign of combined effect changes after the year of 2009 and which factors influence most the sign. Year of 2009 is known as the year when market shifted from Seller's to Buyer's market. We show that 1) integration increases corporate value in general but after 2009 integration significantly decreases the value, 2) the ratios such as Production/Total Cost, Cash turnover period chosen for reversal of the flexibility measure are negatively affect Tobin's Q and especially stronger after 2009. This shows the flexibility improves corporate value and stronger in the recess period (Buyer's market). These results imply that solar company should set up integration strategy considering the tradeoff between efficiency and flexibility and the impact of the business cycle on both factors. Strategy only based on the price competitiveness determined in boom time can bring undesirable outcomes to the company. In addition, Strategic alliances in some value chains as a flexible bondage should be taken in account as complementary choice to the rigid integration.

Study on the Styles of Subcultural Clothing: from 1930s to 1990s (하위문화 맥락에서 본 패션스타일 연구)

  • 양미경
    • Journal of the Korea Fashion and Costume Design Association
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    • v.5 no.1
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    • pp.33-45
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    • 2003
  • This is a study that examines the fashion changes in the 20th century in terms of various subcultures in the period. Starting from defining the concept and the developing process of subculture, this study traces the history of subcultural styles from 1930s to 1990s, focusing on the way each generation resisted the main stream through its styles. This study is intended to provide a theoretical frame on the understanding of subcultural styles, with a close examination of its formative and developing process and characteristics. This study understands subcultural style as a way of deviate or resistant expression within a society. It differentiates itself from the main style by deliberately and publicly asserting its own identity, and, as a result, realizes in the form of fashion its repressed subconsciousness, resistance to the alienation from the society, and deviation from the normative ethics and morality of a society. The four types of subcultural styles presented in chapter 4 are based on their form of resistance, and they are classified and analyzed as follows: The first type is revision, which tries to revise and change the given form by adding new elements. There are two kinds of revision, one is dressing up, which dresses for success, and the other is minimal dressing. Hyperbole is the second type, which resists by emphasizing or hyperbolizing the main stream with its erotic, nihilistic, or dynamic forms. Two kinds of hyperbole are examined, one is hyperbole of masculinity, and the other is ostentatious hyperbole. The third type is reversal and rejection, which reverses the forms from the established sign system into its own secret code, or rejects the traditional taboos. This type include no dressing, and the reversal of sex identity. Isolation and redrawal is the fourth type, which tries to distance itself from the ritual code of the day. This type is divided into dressing of the escape from time, and dressing of the escape from space. The first group of this type is characterized by nostalgia or futurism. An emphasis is given on ethnicity, naturalism, or a closed space within a city in dressing of the escape from space. In conclusion, it can be said that subcultural style puts the foremost importance on individual freedom. Since 1990s, the distinction between the subcultural styles and high fashion gets somewhat blurred, while the liberal, sexual, life stylistic tension between the two groups are heightened.

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The Sublime in Contemporary Fashion - Focused on the Fashion from the Early 90's - (현대 패션에 표현된 숭고미에 관한 연구 - 1990년 이후부터 현재까지의 패션을 중심으로 -)

  • Choi Soo-Hyun
    • Journal of the Korean Society of Costume
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    • v.55 no.7 s.98
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    • pp.114-130
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    • 2005
  • In postmodernism, the sublime that reaches ecstasy overcoming terror or pain is described as the most expressive phenomenon. The purpose of this study is to understand the sublime expressed in contemporary fashion. for this purpose, 1 investigated the theories of the sublime, categorized the definition and modes, then applied those categories for contemporary fashion. Documentary studies were conducted through aesthetic, design and fashion books and the demonstrative studies were processed by analyzing photos from fashion magazines. In the history of aesthetics, the sublime is explained as the ambivalent feeling mixed with pain and pleasure, terror and delight or negation and affirmation. In this study, the sublime could be defined as the aesthetic pleasure through the transcendence of the pain and terror and classified into 3 categories, the tragic, the initiative, and the deconstructive. The tragic sublime that includes the terrific, the disgusting and the religious character is expressed through the image of death or the physical torture, the satanic image or disgusting object and the ascetic image and religious sign or icons. The limitless sublime that includes the giant and the dynamic character is accomplished by consist of the elongation or the enlargement and the powerful authority. The deconsturctive sublime that includes the negative, the indeterminate and the complex character is associated with the deconstruction in style, the reversal of image and the destruction of the space of the body. Analysis on the sublime expressed in contemporary fashion may provide an excellent way for understanding human aesthetic consciousness in dress.

A Study on Dianji(癲疾) in Huangdineijing (『황제내경(黃帝內經)』에 나타난 전질(癲疾)에 대한 고찰(考察))

  • Shin, Sang-won;Kim, Jong-hyun
    • Journal of Korean Medical classics
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    • v.30 no.2
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    • pp.113-131
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    • 2017
  • Objectives : Dianji is a classic mental disorder in oriental medicine. Dian is often used as a name of disease together with Xian and Kuang. However, much confusion arises due to the usage of such words as Diankuang or Dianxian without the full comprehension of these terms' meanings. Dian, especially, is contained in both, so there is a need to clearly define its meaning. Therefore, the paper aims to study in what context Huangdineijing, the oldest classical medical text in oriental medicine, used Dian. Methods : All statements in Huangdineijing containing Dian were studied to create a number of categories. Based on this analysis, the paper attempted to understand Dianji's symptoms, mechanism, natures, and more. Then lastly, the relationship between the usage of Kuang and Xian was pondered upon. Conclusions & Results : The mechanism of pathology of the Dianji in Huangdineijing can be understood within the scope of upper excess and lower deficiency and the reversal of qi. Additionally, Dianji refers to a sickness in the head, and has a essence of spirit disease. Dian and Kuang were expressed as two types of relationship. One expression was a form of symptom that becomes visible during the occurrence phase of Dian, and the other expression was the cases where it was used as an independent sign. On the other hand, there was no case where Xian and Dian were explained in conjunction with each other. However, there still exist some similarities, mainly in that both diseases revolves around epilepsy.