• KSII Transactions on Internet and Information Systems (TIIS)
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• v.5 no.10
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• pp.1862-1878
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• 2011

With the advances in wireless communication technology and the advent of smartphones, research on location-based services (LBSs) is being actively carried out. In particular, several spatial index methods have been proposed to provide efficient LBSs. However, finding an optimal indexing method that balances query performance and index size remains a challenge in the case of wireless environments that have limited channel bandwidths and device resources (computational power, memory, and battery power). Thus, mechanisms that make existing spatial indexing techniques more efficient and highly applicable in resource-limited environments should be studied. Bitmap-based Spatial Indexing (BSI) has been designed to support LBSs, especially in wireless broadcast environments. However, the access latency in BSI is extremely large because of the large size of the bitmap, and this may lead to increases in the search time. In this paper, we introduce a Selective Bitmap-based Spatial Indexing (SBSI) technique. Then, we propose an Adaptive Bitmap-based Spatial Indexing (ABSI) to improve the tuning time in the proposed SBSI scheme. The ABSI is applied to the distribution of geographical objects in a grid by using the Hilbert curve (HC). With the information in the ABSI, grid cells that have no objects placed, (i.e., 0-bit information in the spatial bitmap index) are not tuned during a search. This leads to an improvement in the tuning time on the client side. We have carried out a performance evaluation and demonstrated that our SBSI and ABSI techniques outperform the existing bitmap-based DSI (B DSI) technique.

• Natural Product Sciences
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• v.23 no.1
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• pp.40-45
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• 2017

Epilepsy is a brain disorder that affects millions of people worldwide. It is characterized by recurrent and unpredictable seizures that are usually controlled with antiepileptic/anticonvulsive drugs. However, most antiepileptic drugs produce various side effects such as tolerance and sedation. Thus, there is a growing interest for alternative anticonvulsive drugs, preferably from natural or herbal sources. In this study, we evaluated the anticonvulsive effects of Rehmannia glutinosa (RG). The anticonvulsive effect of RG extract was evaluated using electroshock- and chemical-induced seizure tests in mice. To identify its probable mechanism of action, the effects of RG extract on $Cl^-$ influx was measured in vitro. We found that RG extract has anticonvulsive effects against electroshock-induced seizures, as indicated by an increased seizure threshold in mice. The RG extract also decreased the percentage of seizure responses induced by the GABAergic antagonist, pentylenetetrazole. These results suggest that the anticonvulsive effects of RG extract are mediated through a GABAergic mechanism. In support of this mechanism, our in vitro test showed that RG extract increases intracellular $Cl^-$ influx. Furthermore, RG extract did not show sedative and/or muscle relaxant effects in the open-field and rota-rod tests. Altogether, these results confirm that RG extract could be a herbal anticonvulsant and a potential alternative for clinical use.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.12
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• pp.4568-4587
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• 2014

Authentication of videos and images based on the content is becoming an important problem in information security. Unfortunately, previous studies lack the consideration of Kerckhoffs's principle in order to achieve this (i.e., a cryptosystem should be secure even if everything about the system, except the key, is public knowledge). In this paper, a solution to the problem of finding a relationship between a frame's index and its content is proposed based on the creative utilization of a robust manifold feature. The proposed solution is based on a novel semi-fragile watermarking scheme for H.264/AVC video content authentication. At first, the input I-frame is partitioned for feature extraction and watermark embedding. This is followed by the temporal feature extraction using the Isometric Mapping algorithm. The frame index is included in the feature to produce the temporal watermark. In order to improve security, the spatial watermark will be encrypted together with the temporal watermark. Finally, the resultant watermark is embedded into the Discrete Cosine Transform coefficients in the diagonal positions. At the receiver side, after watermark extraction and decryption, temporal tampering is detected through a mismatch between the frame index extracted from the temporal watermark and the observed frame index. Next, the feature is regenerate through temporal feature regeneration, and compared with the extracted feature. It is judged through the comparison whether the extracted temporal watermark is similar to that of the original watermarked video. Additionally, for spatial authentication, the tampered areas are located via the comparison between extracted and regenerated spatial features. Experimental results show that the proposed method is sensitive to intentional malicious attacks and modifications, whereas it is robust to legitimate manipulations, such as certain level of lossy compression, channel noise, Gaussian filtering and brightness adjustment. Through a comparison between the extracted frame index and the current frame index, the temporal tempering is identified. With the proposed scheme, a solution to the Kerckhoffs's principle problem is specified.

• Journal of Sensor Science and Technology
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• v.23 no.2
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• pp.114-121
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• 2014

We report a polysilicon active area membrane field effect transistor (PSAFET) pressure sensor for low stress deflection of membrane. The PSAFET was produced in conventional FET semiconductor fabrication and backside wet etching. The PSAFET located at the front side measured pressure change using 300 nm thin-nitride membrane when a membrane was slightly strained by the small deflection of membrane shape from backside with any physical force. The PSAFET showed high sensitivity around threshold voltage, because threshold voltage variation was composed of fractional function form in sensitivity equation of current variation. When gate voltage was biased close to threshold voltage, a fractional function form had infinite value at $V_{tn}$, which increased the current variation of sensitivity. Threshold voltage effect was dominant right after the PSAFET was turned on. Narrow transistor channel established by small current flow was choked because electron could barely cross drain-source electrodes. When gate voltage was far from threshold voltage, threshold voltage effect converged to zero in fractional form of threshold voltage variations and drain current change was mostly determined by mobility changes. As the PSAFET fabrication was compatible with a polysilicon FET in CMOS fabrication, it could be adapted in low pressure sensor and bio molecular sensor.

• Journal of Life Science
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• v.19 no.11
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• pp.1666-1671
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• 2009

In Brassica, S locus glycoprotein (SLG) and S locus receptor kinase (SRK) genes function together for self-recognition in the self-incompatibility response. In addition, a water channel called aquaporins (MOD) is required for the self-incompatibility response. In this study, we isolated the SC-SLG, SC-SRK, and SC-MOD genes from a self-compatible line of B. oleracea. In the self-compatible line, the SC-SLG, SC-SRK, and SC-MOD genes showed the highest degree of sequence similarity with published data and to normal expression by RT-PCR. Therefore, it can be concluded that the SCR/SP11 gene of the B. oleracea pollen may not function and/or that mutations may occur in genes for self-incompatibility that are not linked to the S locus region.

• Molecules and Cells
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• v.39 no.3
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• pp.211-216
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• 2016

CYP107W1 from Streptomyces avermitilis is a cytochrome P450 enzyme involved in the biosynthesis of macrolide oligomycin A. A previous study reported that CYP107W1 regioselectively hydroxylated C12 of oligomycin C to produce oligomycin A, and the crystal structure of ligand free CYP107W1 was determined. Here, we analyzed the structural properties of the CYP107W1-oligomycin A complex and characterized the functional role of the Trp178 residue in CYP107W1. The crystal structure of the CYP107W1 complex with oligomycin A was determined at a resolution of $2.6{\AA}$. Oligomycin A is bound in the substrate access channel on the upper side of the prosthetic heme mainly by hydrophobic interactions. In particular, the Trp178 residue in the active site intercalates into the large macrolide ring, thereby guiding the substrate into the correct binding orientation for a productive P450 reaction. A Trp178 to Gly mutation resulted in the distortion of binding titration spectra with oligomycin A, whereas binding spectra with azoles were not affected. The Gly178 mutant's catalytic turnover number for the 12-hydroxylation reaction of oligomycin C was highly reduced. These results indicate that Trp178, located in the open pocket of the active site, may be a critical residue for the productive binding conformation of large macrolide substrates.

• Journal of The Korean Society of Agricultural Engineers
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• v.60 no.1
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• pp.31-36
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• 2018

A rainwater harvesting device was developed for runoff flow harvesting in a small stream or channel and its performance was evaluated in small fields. The rainwater harvesting device has slits on its side of cylindrical volume in 15 cm diameter and 70 cm length, which is designed to increase its water flow harvesting capacity. The maximum collectable water quantity was about 0.0022 ton/sec (130 L/min). Rainwater harvesting device were installed in two locations (P1, P2). P1 is a point for rainfall runoff flow harvesting. P2 is a point for ordinary flow harvesting. During this study, total rainfall depth was 334.5 mm. Runoff of 1,722 ton and 7,984 ton occurred in P1 and P2, and 273 ton and 125 ton were collected by this rainwater harvesting device. Harvesting efficiency was calculated as 15.85 % and 1.57 % in P1 and P2. Clogging of screen filter media in the cylinder due to soil and suspended solids has lowered the harvesting efficiency. However, it was possible to harvest 30 ton/month of rainwater harvesting and it is expected that it will help to solve short-term water shortage.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.38 no.6
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• pp.390-397
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• 2001

A novel self-aligned ESD (Elevated Source Drain) MOSFET structure which can effectively reduce the GIDL (Gate-Induced Drain Leakage) current is proposed and analyzed. The proposed ESD structure is characterized by sidewall spacer and recessed-channel depth which are determined by dry-etching process. Elevation of the Source/Drain extension region is realized so that the low-activation effect caused by low-energy ion implantation can be avoided. Unlike the conventional LDD structures, it is shown that the GIDL current of the ESD structure is suppressed without sacrificing the maximum driving capability. The main reason for the reduction of GIDL current Is the decreased electric field at the point of the maximum band-to-band tunneling as the peak electric field is shifted toward the drain side.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.4
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• pp.379-386
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• 2004

OFDM(orthogonal frequency division multiplexing) communications system is very attractive for the high data rate transmissionin the frequency selective fading channel. Since OFDM has high PAPR(peak-to-average power ratio), OFDM signal may be distorted by the nonlinear HPA(high power amplifier). In this paper, we propose an improved dummy sequence scheme for reducing the PAPR in OFDM communication system. This method inserts each different dummy sequence at the predefined sub-carriers fur PAPR reduction. After IFFT, the OFDM data signal with the lowest PAPR is selected to transmit. The complementary sequence is used as dummy sequence. So, it can cut down the computation time and quantity because it dose not require the peak value optimization for finding the phase rotation factor and the transmission of the side information about the rotation factor unlike the PTS method.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.26 no.3
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• pp.587-601
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• 2016

In this paper we suggest method for scalar recoding which is both secure against SPA and DPA. Suggested method is countermeasure to power analysis attack through scalar recoding using negative expression. Suggested method ensures safety of SPA by recoding the operation to apply same pattern to each digit. Also, by generating the random recoding output according to random number, safety of DPA is ensured. We also implement precomputation table and modified scalar addition algorithm for addition to protect against SPA that targets digit's sign. Since suggested method itself can ensure safety to both SPA and DPA, it is more effective and efficient. Through suggested method, compared to previous scalar recoding that ensures safety to SPA and DPA, operation efficiency is increased by 11%.