• Korean Journal of Radiology
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• 제24권3호
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• pp.247-258
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• 2023

Objective: To localize the neuroanatomical substrate of rapid eye movement sleep behavior disorder (RBD) and to investigate the neuroanatomical locational relationship between RBD and α-synucleinopathy neurodegenerative diseases. Materials and Methods: Using a systematic PubMed search, we identified 19 patients with lesions in different brain regions that caused RBD. First, lesion network mapping was applied to confirm whether the lesion locations causing RBD corresponded to a common brain network. Second, the literature-based RBD lesion network map was validated using neuroimaging findings and locations of brain pathologies at post-mortem in patients with idiopathic RBD (iRBD) who were identified by independent systematic literature search using PubMed. Finally, we assessed the locational relationship between the sites of pathological alterations at the preclinical stage in α-synucleinopathy neurodegenerative diseases and the brain network for RBD. Results: The lesion network mapping showed lesions causing RBD to be localized to a common brain network defined by connectivity to the pons (including the locus coeruleus, dorsal raphe nucleus, central superior nucleus, and ventrolateral periaqueductal gray), regardless of the lesion location. The positive regions in the pons were replicated by the neuroimaging findings in an independent group of patients with iRBD and it coincided with the reported pathological alterations at post-mortem in patients with iRBD. Furthermore, all brain pathological sites at preclinical stages (Braak stages 1-2) in Parkinson's disease (PD) and at brainstem Lewy body disease in dementia with Lewy bodies (DLB) were involved in the brain network identified for RBD. Conclusion: The brain network defined by connectivity to positive pons regions might be the regulatory network loop inducing RBD in humans. In addition, our results suggested that the underlying cause of high phenoconversion rate from iRBD to neurodegenerative α-synucleinopathy might be pathological changes in the preclinical stage of α-synucleinopathy located at the regulatory network loop of RBD.

• Structural Engineering and Mechanics
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• 제90권6호
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• pp.543-549
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• 2024

The utilization of the fabric materials for lightweight building structures has attracted considerable attention due to the multiple functions and high strength-to-weight ratio. The mechanical properties of the fabric materials evolve with the loading cycle, especially for the Poisson's ratio that requires the full cyclic strain to determine the accurate values. The digital image correlation method has been justified but needs to meet the flexibility and complexity requirements of the fabric materials. This paper thus proposes a modified digital image correlation method to quantify the Poisson's ratio of fabric materials. To obtain the accurate Poisson's ratio of fabric materials in the cyclic experiments using non-contact measuring method, a speckle generation of the digital image correlation method is implemented to obtain the strain distribution and strain characteristics. The uniaxial cyclic experiments for the fabric materials are carried out in the warp, weft and 45° directions. The digital image correlation photos are taken when the material properties become stable in the cyclic loading. The results show that the strain distributions are non-uniform and dependent on the specimen directions. The reliable Poisson's ratios of the fabric materials in the warp, weft and 45° directions are 0.016, 1.2 and 2.6. The strain asymmetry at the maximum strain position is related with the weaving architecture. These observations and results are indispensable to understand the Poisson's ratios of fabric materials and to guide the proper analysis of the large-span membrane structures.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.83-90
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• 2009

Natural disasters, such as the recent floods in the Midwest, Hurricane Ike in the Gulf coast region (U.S.), and the earthquake in Sichuan (China), cause severe damage to the infrastructure as well as the associated industries and communities that rely on the infrastructure. The estimated damages due to Hurricane Ike in 2008 were a staggering $27 billion, the third worst in U.S. history. In addition, the worst earthquake in three decades in Sichuan resulted in about 90,000 people dead or missing and $20 billion of the estimated loss. A common observation in the analyses of these natural disaster events is the inadequacy of critical infrastructure to withstand the forces of natural calamities and the lack of mitigation strategies when they occur on the part of emergency-related organizations, industries, and communities. If the emergency-related agencies could identify and fortify the vulnerable critical infrastructure in the preparedness stage, the damage and impacts can be significantly reduced. Therefore, it is important to develop a decision support system (DSS) for identifying region-specific mitigation strategies based on the inter-relationships between the infrastructure and associated industries and communities in the affected region. To establish effective mitigation strategies, relevant data were collected from the affected areas with respect to the technical, social, and economic impact levels. The data analysis facilitated identifying the major factors, such as vulnerability, criticality, and severity, for developing a DSS. Customized mitigation strategies that will help agencies prepare, respond, and recover according to the disaster response were suggested.

• Journal of Ginseng Research
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• 제43권4호
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• pp.600-605
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• 2019

Background: The leaves and roots of Panax ginseng are rich in ginsenosides. However, the chemical compositions of the leaves and roots of P. ginseng differ, resulting in different medicinal functions. In recent years, the aerial parts of members of the Panax genus have received great attention from natural product chemists as producers of bioactive ginsenosides. The aim of this study was the isolation and structural elucidation of novel, minor ginsenosides in the leaves of P. ginseng and evaluation of their antiinflammatory activity in vitro. Methods: Various chromatographic techniques were applied to obtain pure individual compounds, and their structures were determined by nuclear magnetic resonance and high-resolution mass spectrometry, as well as chemical methods. The antiinflammatory effect of the new compounds was evaluated on lipopolysaccharide-stimulated RAW 264.7 cells. Results and conclusions: Two novel, minor triterpenoid saponins, ginsenoside $LS_1$ (1) and 5,6-didehydroginsenoside $Rg_3$ (2), were isolated from the leaves of P. ginseng. The isolated compounds 1 and 2 were assayed for their inhibitory effect on nitric oxide production in LPS-stimulated RAW 264.7 cells, and Compound 2 showed a significant inhibitory effect with $IC_{50}$ of $37.38{\mu}M$ compared with that of NG-monomethyl-L-arginine ($IC_{50}=90.76{\mu}M$). Moreover, Compound 2 significantly decreased secretion of cytokines such as prostaglandin $E_2$ and tumor necrosis factor-${\alpha}$. In addition, Compound 2 significantly suppressed protein expression of inducible nitric oxide synthase and cyclooxygenase-2. These results suggested that Compound 2 could be used as a valuable candidate for medicinal use or functional food, and the mechanism is warranted for further exploration.

• Mycobiology
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• 제49권1호
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• pp.78-85
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• 2021

Morels (Morchella spp.) are valuable medicinal and edible mushrooms. In this study, chemical profiles of aromas and lipophilic extracts of black morel (Morchella importuna) grown in China were analyzed by gas chromatography/mass spectroscopy, along with the evaluation of antioxidant and antimicrobial activities for the lipophilic extracts. Sixty-five compounds in total were identified from the aromas, and 1-octen-3-ol was the main component for aromas of fresh (34.40%) and freeze-dried (68.61%) black morels, while the most abundant compound for the aroma of the oven-dried sample was 2(5H)-furanone (13.95%). From the lipophilic extracts, 29 compounds were identified with linoleic acid as the main compound for fresh (77.37%) and freeze-dried (56.46%) black morels and steroids (92.41%) as the main constituent for an oven-dried sample. All three lipophilic extracts showed moderate antioxidant activities against 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) with the IC50 values ranging 7.56~17.52 mg/mL and 5.75~9.73 mg/mL, respectively, and no obvious antimicrobial activity was observed for lipophilic extracts. The drying methods affect the chemical profile of black morel, and freeze-drying was favorable for retaining nutrients and morel smell. This is the first report on the aroma and lipophilic extracts of M. importuna grown in China.

• 한국의류학회지
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• 제38권1호
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• pp.110-122
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• 2014

This study examined hwangbek dyeability for cotton, silk, and wool from different tree species and origin as well as their berberine and palmatine content. A total of 12 different hwangbek were examined, six purchased directly from different locations of China and six purchased from the Seoul Medicine Market. Hwangbek purchased from China were 3 Kwanhwangbek (Phellodendron amurense Rupr.) from Jilin, Liaoning, Heilongjiang and 3 Chunhwangbek (Phellodendron chinense Schneid.) from Sichuan, Yunnan, and Guangxi. Hwangbek purchased from the Seoul Medicine Market included 3 hwangbek that originated from Korea and 3 hwangbek imported from China. We extracted 2.5g of each hwangbek into 500mL of water for 60 min at $80^{\circ}C$. Dyeing was conducted using the IR dyeing machine for 30min at $55^{\circ}C$ using a 1:100 liquor ratio. Cotton was mordanted using tannic acid followed by potassium antimonyl tartrate trihydrate treatment before dyeing. Berberine and palmatine pigments in hwangbek were identified with the HPLC-DAD-MS instrument and the amount of pigment was quantified using an ion chromatogram. The results indicated that the K/S values of dyed fabrics were highly related to the amount of pigment in hwangbek used for dyeing.

• Journal of the Optical Society of Korea
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• 제20권4호
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• pp.476-480
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• 2016

For the application of multiusers, the arrangement and distribution of the keys is a much concerning problem in a cryptosystem. In this paper, we propose an optical encryption scheme with multiple users based on computational ghost imaging (CGI) and orthogonal modulation. The CGI encrypts the secret image into an intensity vector rather than a complex-valued matrix. This will bring convenience for post-processing and transmission of the ciphertext. The orthogonal vectors are taken as the address codes to distinguish users and avoid cross-talk. Only the decryption key and the address code owned by an authorized user are matched, the secret image belonging to him/her could be extracted from the ciphertext. Therefore, there are two security levels in the encryption scheme. The feasibility and property are verified by numerical simulations.

• 국제교류와 융합교육
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• 제3권1호
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• pp.105-113
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• 2023

한국은 자타가 공인하는 교육 강국으로, 역사상 한국 정부는 기초 교육과 농촌교육을 중요시 해 왔다. 한국 정부는 일련의 교육 정책과 교육에 관한 조치를 반포하여 실시함과 동시에 재정 방면에서도 농촌 기초 교육의 발전에 극대한 지지를 하였다. 이에 농촌 기초 교육 사업의 발전을 촉진하고, 한국이 세계 교육 강국이 될 수 있는 튼튼한 기초와 힘께 농총 경제의 보장을 마련하였다. 최근 중국은 교육 강국 전략과 도시화 건설 전략이 계속 추진되면서 농촌 지역의 기초 교육 문제가 주목을 받게 되었다. 주목과 더불어 농촌 기초 교육의 발전 방향과 사고 또한 뜨거운 이슈가 되었다. 본 논문은 한국 농촌 기초 교육에 대한 개혁을 살펴보고 분석함으로써 향후 중국 농촌 기초 교육의 발전 대안에 대해 논하고자 한다.

• Journal of Korea Trade
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• 제27권1호
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• pp.119-138
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• 2023

Purpose - This research is to empirically explore the differences in apparel consumption among male and female teenagers and college students in Korea and China. By conducting a survey to understand customers' needs and behaviors, fashion businesses will be able to improve their customer satisfaction and avoid redundancy, inventory, and the waste of resources, effort and money. Design/methodology - The research design considers the consumption patterns of male and female high school and college students in Korea and China. To analyze the data, the study employs decision trees, a type of machine learning algorithm. A decision tree model was developed to examine the relationship between the explanatory and response variables, which can be either quantitative or qualitative in nature. Findings - The main findings of this study indicate that there are differences in shopping behavior among different customer segments. The results show that men have a simpler shopping behavior compared to women. Additionally, cultural factors and the difference in fashion needs between students and non-students have a significant impact on the shopping choices of Chinese and Korean individuals. Originality/value - Existing studies often assume that the shopping behavior of high school and university students is similar and that there are no significant differences in clothing purchases between men and women across countries. The results provide valuable insights into the unique shopping behavior of different customer segments, and can inform fashion businesses in their efforts to meet the needs of their customers.

• 한국지역지리학회지
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• 제8권1호
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• pp.65-82
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• 2002

중국 사천분지 서부의 도강언 관개시설은 기원전 3세기에 진의 촉군 태수였던 이빙에 의하여 축조되었다. 이 시설은 대규모 거 관개의 효시로서 민강의 곡구에 입지한다. 이 지점은 이 지역에서 남쪽의 장강으로 합류하는 다른 강들의 곡구보다 해발고도가 높아 관개의 효율성이 크고, 강수량, 하계 등의 여건상 풍부한 유량을 지닌다. 이런 점에서 이 지점은 일찍이 거 관개시설의 입지로 선정되었다. 이 시설은 곡구에서 유수를 양분하는 '금강제'와 '어취', 유로변경을 위한 '보병구' 그리고 홍수와 토사를 배출하는 '비사언' 등으로 구성되었다. 이들은 상호 유기적으로 수재와 갈수 현상을 동시에 방지하였다. 여기에는 유수의 곡류현상과 침식, 운반. 퇴적작용, 그리고, 암석의 풍화과정 등의 원리가 이미 적용되었다. 한편 성도평원에는 개착된 10여 개 인공수로들의 일부가 동쪽의 부강 유역까지 이어졌었는데, 이 사실은 간과되어 왔다. 결국 이 시설은 민강을 수원으로 이 지역의 수전농업 발전을 주도함으로써 '천부지국'을 이주는 계기가 되었다.