• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제24권4호
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• pp.220-227
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• 2013

Objectives : This study aims to investigate the clinical characteristics and neuropsychological profiles of children with attention-deficit hyperactivity disorder (ADHD) and their siblings. Methods : Eighteen children (age $8.2{\pm}1.7$ years, 12 boys) with ADHD and their 18 siblings (age $7.8{\pm}1.6$ years, 8 boys) completed Continuous Performance (CPT), Stroop, Children's Trail Making, Rey-Kim Memory, and Kim's Frontal Executive Function tasks. The parents of these subjects underwent the Attention-Deficit/Hyperactivity Disorder Rating Scale (ARS), 10-item Parent General Behavior Inventory (P-GBI), and the Social Responsiveness Scale (SRS). Paired t-tests were used. Results : The inattention (p=.020), and hyperactivity-impulsivity (p=.001), scores of the ARS and the P-GBI score (p=.004) were significantly higher in children with ADHD than in their siblings. Deficits in social communication and motivation on SRS were higher in children with ADHD than in their siblings (p=.017 and p=.011, respectively). Z-scores of omission and commission errors as well as response time variability on visual CPT and omission errors on auditory CPT were in clinically significant range, and z-score of omission errors on auditory CPT was in borderline range in siblings. Omission (p=.018) and commission errors on Visual CPT (p=.007) were significantly higher in children with ADHD compared to their siblings. Recognition efficiency on Kim's Frontal Executive Function Task was lower in children with ADHD compared to their siblings, but in normal range in both groups. Stroop interference and figure fluency on Kims Frontal Executive Function Task were in borderline range in ADHD group, and figure fluency was in borderline range in siblings. Conclusion : Our results support a preliminary evidence for mild degree of attention deficit in ADHD siblings. Further studies are needed to examine the cognitive functions of siblings with ADHD in larger samples.

• Clinical and Experimental Pediatrics
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• 제45권12호
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• pp.1540-1545
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• 2002

목 적 : 방광요관역류는 국외의 연구에 의하면 가족력이 중요하며 무증상 형제 자매에서의 방광요관역류 발생빈도가 26-51%의 높은 빈도로 보고되고 있고 역류성 신병증, 소아 고혈압, 만성 신부전으로 진행될 수 있으므로 선별검사의 중요성이 강조되어 왔는데 우리나라 소아에서도 무증상 형제 자매의 방광요관역류 빈도를 조사하여 선별검사의 근거를 제시하고자 본 연구를 시행하였다. 방 법: 인제대학교 의과대학 상계백병원에 내원하여 방광요관역류로 진단받은 환아 중 VCUG 검사에 동의한 28명의 무증상 형제 자매를 대상으로 하였고 방광요관역류 환아의 무증상 형제 자매 중 VUR로 진단받은 형제 자매는 모두 DMSA 신스캔을 시행하였다. 결 과 : VUR로 진단받은 환아는 총 28명이고 남아 14 명, 여아 14 명, 나이는 1개월에서 8년 5개월로 평균 2.7세였다. VCUG 검사에 동의한 무증상 형제 자매는 총 28명으로 남아 17명, 여아 11명, 나이는 2개월에서 7년 5개월로 평균 3.3세였다. VUR로 진단된 환아 28명 중 20례에서 신손상이 있어 전체적으로 71.4%의 신손상의 빈도를 보였다. 무증상 형제 자매 28명 중 VCUG 검사상 VUR로 진단된 형제 자매는 3명으로 10.7%의 VUR 발생빈도를 보였고 DMSA 신스캔 상 이상이 발견된 경우는 1명이였다. 결 론 : 방광요관역류 환아의 무증상 형제 자매에서 역류빈도는 10.7%로 조사되어 방광요관역류의 위험인자로서 가족력이 중요함을 제시해주고 있으며 방광요관역류의 가족선별검사의 근거를 확립하기 위해서 앞으로 더 많은 연구가 시행되어야 하겠다.

• Child Health Nursing Research
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• 제23권3호
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• pp.394-404
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• 2017

Purpose: The purpose of this study was to review interventions available to nurses caring for siblings of children with cancer. Methods: Searches of CINAHL, MEDLINE, PubMed, EMBASE, and RISS identified ten intervention studies published from January, 2000 to November, 2016. Results: Ten studies on interventions for siblings of pediatric cancer patients were identified as follows: 4 included camps, 4 included support groups, and 2 provided individual interventions. Theoretical frameworks were mainly cognitive behavioral theory and most studies were led by psychologists and multidisciplinary teams. The purpose of the interventions was primarily enhancing psychosocial adjustment. Siblings' fear of disease, self-esteem, and social support were improved significantly after the interventions. Findings were inconsistent with regard to depression, anxiety, behavioral problems, post-traumatic stress, health-related quality of life, and siblings' perceptions of the illness. Conclusion: Study findings showed the potential for enhancing emotional and behavioral outcomes in siblings of children with cancer. However, the number of studies was very small, and several methodological limitations were identified. In the future, more randomized controlled trials with larger samples are needed to extend the evidence base. Moreover, future research should identify sibling's characteristics and circumstances most likely to bring benefits to the siblings.

• 아동학회지
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• 제31권3호
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• pp.199-214
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• 2010

This study examined the effects of siblings, emotional intelligence (E.I.), and conflict solving strategies (integrating-compromising strategy/ dominating strategy) on children's social competence. The subjects were 421 6th graders (231 boys, 190 girls) in Seoul. The children filled out questionnaires on their siblings, E.I., and conflict solving strategies. Their teachers were asked to rate the children's social competence. Mediational analyses were conducted using structural equation modeling. Both integrating-compromising strategies and dominating strategies mediated the relationship between E.I. and social competence. Children with higher E.I. reported that they used more integrating-compromising strategies, which in turn was related to higher social competence. Those who scored low on E.I. reported that they used more dominating strategies, which in turn was related to lower social competence. Although the effects of siblings did not have any direct effects on social competence, it was found to be related to the type of conflict solving strategies most frequently used. Compared to the children with siblings, the children without siblings used more dominating strategies, which in turn contributed to lower social competence.

• 생물정신의학
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• 제23권4호
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• pp.179-184
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• 2016

Objectives This study was conducted to investigate the possibility of neurological soft signs as an endophenotype for schizophrenia by examining neurological soft signs in patients, their unaffected siblings and normal comparison subjects. Methods The study sample consisted of 32 patients, 25 of their unaffected siblings and 30 normal comparison subjects. Neurological soft signs were evaluated using the Cambridge Neurological Inventory Part 2. soft sign assessment. Results The patients were significantly more impaired than normal comparison subjects (p = 0.047) on primitive reflex. The patients were significantly more impaired than siblings (p = 0.004) and normal comparison subjects (p = 0.021) on motor coordination. The siblings performed better on sensory integration than the patients (p = 0.020) and normal comparison subjects (p = 0.036). Conclusions This study suggests that neurological soft signs might be a potential biomarker for schizophrenia, but might not be an endophenotype for schizophrenia.

• 사회복지연구
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• 제37호
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• pp.63-89
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• 2008

본 연구는 성인 지적장애인의 비장애 형제들이 장애형제의 미래부양에 대해 갖는 책임감에 영향을 미치는 요인들을 규명하고자 하였다. 이를 위해 서울지역 8개 장애인종합복지관에서 서비스를 이용하는 만18세 이상의 성인 지적장애인을 형제로 두고 있는 비장애 형제들을 대상으로 설문조사를 실시하였다. 총132명의 자료가 최종 분석에 이용되었고, 다중회귀분석방법을 활용하여 지적장애인의 특성 요인 모형, 비장애형제의 특성 요인 모형, 관계적 요인 모형, 종합모형으로 분석하였다. 연구 결과, 지적장애인의 특성 요인에서는 장애정도가, 관계적 요인에서는 형제 간 친밀도와 사회적 지지가 유의미한 영향을 미치는 것으로 나타났다. 최종 종합모형에서는 장애 정도, 비장애형제의 성, 형제 간 친밀도와 사회적 지지가 유의미한 영향을 미치는 것으로 나타났으며, 이중 형제 간 친밀도와 사회적 지지를 포함한 관계적 요인이 부양 책임감을 예측하는 가장 중요한 요인인 것으로 밝혀졌다. 본 결과를 통해 지적장애인과 비장애 형제가 서로 간에 믿음과 이해를 증진시킬 수 있는 형제프로그램의 개발 및 확산이 요구되는 한편, 비장애형제가 가족이나 친구, 그 밖의 주변 사람들로부터 지지를 받을 수 있도록 대인관계망을 넓혀가도록 돕는 것이 중요하며, 또한 장애의 의존도에 따라 부양의 어려움을 경감시키기 위해 상이하게 접근할 필요가 있음을 시사하였다.

• 병원약사회지
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• 제35권4호
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• pp.400-408
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• 2018

Background : Palivizumab is an intravenous monoclonal antibody which is used in the prevention of respiratory syncytial virus (RSV) infection. It is currently recommended for infants who are at high-risk for RSV infections due to preterm birth or other medical conditions such as congenital heart disease. Palivizumab is a humanized monoclonal antibody directed against an epitope in the antigenic site A of the protein F of RSV particles. Palivizumab is given once a month via intramuscular (IM) injection throughout the duration of the RSV season. Since palivizumab is known to have preventive effects against RSV infection for children with older siblings, the insurance coverage for palivizumab was expanded in October 2016. Methods : The electronic medical records of children under 2 years old who have older siblings who visited or were admitted to the Severance Hospital from October 2015 to May 2016 and from October 2016 to May 2017 were reviewed retrospectively. The data were then divided into two groups depending on the pilivizumab administration. Results : A total of 67 patients were enrolled in this study. The effectiveness in the reduction of hospitalization was statistically significant (p=0.009). Palivizumab decreased respiratory symptoms such as cough, rhinorrhea, and fever in patients with older siblings (p 0.05). Conclusions : In this study, palivizumab administration was effective in preventing RSV infection in infants with older siblings. Expanding palivizumab-prophylaxis administration to infants with older siblings may be effective in the prevention of upper respiratory infections.

• 아동학회지
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• 제35권2호
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• pp.63-84
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• 2014

The purpose of this study was to explore the effects of parental differential treatment and social support perceived by adolescents with siblings with special needs on their self-esteem and internalized problems. The subjects comprised one hundred 12- to 18-year-old adolescents with siblings with special needs. The major results of this study were as follows. First, there were significant differences in adolescents' self-esteem by participation in support programs for siblings of children with special needs. Second, there was no significant effect of parental differential treatment on adolescents' self-esteem. Third, there was a significant effect of social support (family, friends, and teachers) on adolescents' self-esteem. Fourth, there was no effects of paternal differential parenting on adolescents' internalized problems. However, there was a significant effect of differential maternal affection on adolescents' internalized problems. Fifth, there was a significant effect of social support, especially in terms of support provided by friends, on adolescents' internalized problems. In conclusion, social support and differential maternal affection both have an important role in adolescents' self-esteem and internalized problems.

• 대한가정학회지
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• 제39권4호
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• pp.79-89
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• 2001

This study investigated institutionalized children's behavior problems depending on their family networks. Subjects were 250 institutionalized children in 15 child-welfare facilities in Seoul(132 preschooler, 55 first and 63 second grade children; 144 boys and 106 girls). Data were analyzed with t-test, ANOVA, and Duncan test. Measures of behavior problems included internalizing (anxiety, immaturity, withdrawal, physical symptom) and externalizing behavior problems (hyperactivity, aggression). Results showed that institutionalized children having parents were higher in internalizing problems than children not having parents, while children living with siblings in the facilities were lower in externalizing problems than children living without siblings. Furthermore, institutionalized children having parents and living without siblings were higher in both internalizing and externalizing problems than children not having parents and living with siblings.

• 아동학회지
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• 제10권1호
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• pp.43-63
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• 1989

The present study compared mother-child relationships and sociability of only children with that of children with siblings. The mother of 105 only children and 179 children with siblings responded to questionnaires on maternal attitudes and children's sociability. The children were all enrolled in kindergartens in Seoul. The data analysis was with t-test and Pearson's correlation. The mothers of only children reported that they were more overprotective and obedient to the children than mothers of children with siblings. Only children were less autonomous in sociability than children with siblings. 'Protective' and 'obedient' attitudes of mothers of only children were positively correlated with the 'egocentrism' of the child and negatively correlated with 'autonomy' of the child.