• Journal of Genetic Medicine
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• v.6 no.1
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• pp.56-61
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• 2009

Purpose: Preeclampsia is a multifactorial disorder with genetic and environmental components. Recently, the STOX1 gene, identified as a candidate gene for preeclampsia in Dutch women, has been shown to be placentally expressed and subject to imprinting with preferential transmission of the maternal allele. The purpose of this study is to investigate whether there is an association between the STOX1 Y153H variation and preeclampsia in Korean pregnant women. Materials and Methods: This study involved 202 preeclamptic and 204 healthy pregnant women who were genotyped for the Y153H variant of the STOX1 gene using a commercially available SNapShot assay kit and an ABI Prism 3730 DNA Analyzer. Results: There were no significant differences in genotype frequencies of the Y153H variant of the STOX1 gene between preeclamptic patients and normal controls (P>0.05). The H allele frequency of the STOX1 Y153H variation was similar in patients with preeclampsia (87.1%) and in normal controls (86.5%). In addition, multiple logistic regression analysis showed that the YH, HH, and YH/HH genotypes were not associated with an increased risk of preeclampsia when compared to the YY genotype. Conclusion: This is the first study to characterize the Y153H variant of the STOX1 gene in Korean patients with preeclampsia. We found no differences in the genotype and allele frequencies between preeclamptic and normal pregnancies. Although limited by a relatively small sample size, our study suggests that the STOX1 Y153H variation is not associated with the development of preeclampsia in Korean pregnant women.

• Journal of Genetic Medicine
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• v.8 no.2
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• pp.113-118
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• 2011

Purpose: Placental corticotropin-releasing hormone receptor type 1 (CRHR1) expression is reduced in pregnancies with abnormal placental function such as preeclampsia (PE), and the levels and/or function of CRHR1 are genetically influenced. The aim of this study was to investigate the association between the c.33+8199C>T polymorphism in the CRHR1 gene and PE in a Korean population. Materials and Methods: Using a case-control design, the association between the CRHR1 polymorphism and the risk of PE was investigated in 203 individuals with PE and 211 normotensive controls. Genotypes were determined using a SNapShot kit and an ABI Prism 3100 Genetic analyzer. Results: Genotypes and allele frequencies for the CRHR1 polymorphism did not differ between PE and normotensive pregnancies. The variant T allele was more frequent than the ancestral C allele in both of the groups and was more frequent in the controls than in the cases. In risk analysis for PE, there was not an increased risk of preeclampsia in subjects who were concomitant homozygous rare allele genotypes (CC) (OR, 0.3; P=0.15) or heterozygous rare allele genotypes (TC) (OR, 0.8; P=0.29). There were no differences in the complications of PE such as severity or preterm delivery in patients with the CRHR1 polymorphism. Conclusion: Our findings indicate that the CRHR1 polymorphism was not associated with PE in the present Korean study group.

• Journal of Digital Convergence
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• v.11 no.2
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• pp.385-390
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• 2013

The meaning of things appeared in the frame vary according to how they look in a shot. Especially, position of frame shows how a form becomes a content in quality. This has a large impact on communication with audiences, reminds them a special feeling or atmosphere toward an object and plays a suggestive role for things that shows up. Thus, this study aimed to investigate how symbolisms appeared in the frame position are shown in the relation among characters' narrative, personality and conflict and understand correlation between frame position and characters accordingly. As an object to be analyzed, this study selected which was played with narratives of couples with different personalities. The results of analysis shows that it is deeply associated with couples' narrative, which means that trauma or the severance of relations between a couple is shown on left side, whereas a positive and future-oriented couple was mainly shown on right side and the rate of being situated in the center turned out to be high according to the power relations of love. Based on the comparison between symbolism appeared according to the frame position and narratives and traumas that various characters have, this study found that frame position is playing an important role in composing characters' personality.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.1
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• pp.47-53
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• 2011

From 12 to 16 July 2006, 4 days' torrential rainfall in Deoksan-ri, Inje-up, Inje-gun, Gangwon-do caused massive landslide and debris flow. Huge losses of both life and property, including two people buried to death in submerged houses, resulted from this disaster. As the affected region is mostly mountainous, it was difficult to approach the region and to estimate the exact extent of damage. But using aerial photographs, we can define the region and assess the damage quickly and accurately. In this study the debris flow region in inje, Gangwon-do was analyzed using aerial photographs. This region was divided into three sections - beginning section, flow section and sedimentation section. Informations for each section were extracted by digitizing the shot images with visual reading. Topographic, forest physiognomic and soil characteristics and debris flow occurrences of this region were analyzed by overlaying topographic map, forest type map and soil map using GIS. Comprehensive analysis shows that landslide begins at slope of about $36^{\circ}$, flows down at $26^{\circ}$ slope, and at $21^{\circ}$ slope it stops flowing and deposits. Among forest physiognomic factors, species of trees showd significant relationship with debris flow. And among soil factors, effective soil depth, soil erosion class, and parent materials showed meaningful relationship with debris flow.

• Journal of Korea Multimedia Society
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• v.7 no.2
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• pp.223-230
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• 2004

A shooting game is all game genres that hit targets through shooting. It include a lot of genres from a flying shot of game room to a personal shooting action game. In this point, a shooting game was regarded it as the origin of all game and it was developed from the early days of game. At present we can meet it in an electronic game room or personal computer, and mobile phone etc.. The popularity of shooting game caused to take aim by simple system, interface, and speedy play. Also it was enticed everyone to enjoy it easily. A shooting games is worked from old like ways until recently and a process of playing game is intuitive than another game. Therefore it popular with a PC player as well as persons of all levels. Beginners can train this game easily through direction such as control way of object, advent way of enemy aircraft and scroll way of background. But as an usability of working and controlling game, beginners of game development can pass over a shooting sense that shout and hit basically. And after design, they will feel that cannot convey realistic effect and thrill etc.. At a result, hitting sense happens to graphic elements and sound. Therefore a measure of effect on these elements is started from analysis of good shooting game. This study was to focus on the advance effect of hitting sense in shooting game through analysis centered for 'the Beetlewing' and '1945 Plus'.

• Analytical Science and Technology
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• v.31 no.2
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• pp.65-70
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• 2018

This study compared two methods for preparing ancient DNA (aDNA) for the construction of successful shotgun libraries that may be applied to massive parallel sequencing. For the comparative analysis, the DNA of prehistoric rib samples from Hungary was extracted using either a manually prepared silica suspension or the Amicon Ultracel-15 10K ultracentrifugal device (Millipore). After the extraction of the same amount of bone powder (about 150 mg) from three samples by each method, the amount of extracted double-stranded DNA and the subsequent degree of construction of the shotgun library were analyzed. The Amicon device method was rapid and easier to perform and resulted in an approximately 11-fold higher DNA recovery than that obtained using the silica suspension. The shotgun library constructed using DNA templates prepared by the Amicon device was more successful than that constructed from templates isolated using the silica suspension. The comparative study of these two aDNA extraction methods showed that the Amicon device has the advantages of saving time, process simplicity, and high efficiency.

• Cartoon and Animation Studies
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• s.40
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• pp.397-421
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• 2015

Aristotle's Poetics is the earliest work of dramaturgy. It explains some of the most important narrative notions, for example, Mimesis, Katharsis, Mythos(Plot), Ethos(Character), Anagnorisis and Peripeteia. etc. Aristotle considered the plot which is the arrangement of events, as the most important element of drama. This paper presents an example of a plot configuration as an alternative to the traditional narration used since Aristotle. Dead Island, developed by Techland and published by Deep Silver, is one of the most successful action role-playing survival zombie video games. Its trailer, the Winner of Gold Prize for Internet Film at Cannes Lions International Festival of Creativity in 2011. Since the purpose of the trailer is to attract the audiences/gamers to the film/game, it has generally a similer narrative method from its own works. But Dead Island trailer is different. We treat this trailer as an short animation. It could be a new example of the non-linear narrative by the control of the time for example, temporal arrangement, direction and speed. We analyse all shots of Dead Island's trailer with Poetics' rules and with $G{\acute{e}}rard$ Genette's some narrative notions for example temporal order and duration. Furthermore we look for how to maximize the audiences' curiosity by the adjustment of the time, combined with its shocking images.

• Journal of Korea Water Resources Association
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• v.53 no.2
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• pp.97-105
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• 2020

Recently, Artificial Neural Network receives attention as a data prediction method. Among these, a Long Shot-term Memory (LSTM) model specialized for time-series data prediction was utilized as a prediction method of hydrological time series data. In this study, the LSTM model was constructed utilizing deep running open source library TensorFlow which provided by Google, to predict inflows of multipurpose dams. We predicted the inflow of the Yongdam Multipurpose Dam which is located in the upper stream of the Geumgang. The hourly flow data of Yongdam Dam from 2006 to 2018 provided by WAMIS was used as the analysis data. Predictive analysis was performed under various of variable condition in order to compare and analyze the prediction accuracy according to four learning parameters of the LSTM model. Root mean square error (RMSE), Mean absolute error (MAE) and Volume error (VE) were calculated and evaluated its accuracy through comparing the predicted and observed inflows. We found that all the models had lower accuracy at high inflow rate and hourly precipitation data (2006~2018) of Yongdam Dam utilized as additional input variables to solve this problem. When the data of rainfall and inflow were utilized together, it was found that the accuracy of the prediction for the high flow rate is improved.

• Broadcasting and Media Magazine
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• v.10 no.1
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• pp.99-112
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• 2005

Christian Metz, the precursor of cine-semiology, considered cinema as a language in the sense that it is a set of messages grounded in a given matter of expression, and a signifying practice characterized by specific codifications. According to Metz, film forms a structured network produced by the interweaving of cinematic codes, within which cinematic subcodes represent specific usages of the particular code. For Metz, cinematic language is a totality of cinematic codes and subcodes, and history of the cinema is the trace of the competition, incorporations and exclusions of the subcodes. He also suggested a filmic text is not just a list of codes in effect, but a process of constant displacement and deformation of codes. Following Metz' textual analysis methodology, I investigated the formal configuration of Hayao Miyazaki‘s animation, Spirited Away. It is interesting to trace the interweaving of cinematic codes in Spirited Away, i.e. codes of lighting, color, movement, and auteurism, across the animation. I focused on the first scene at the bridge to Yubaba's bathhouse, analyzing each cinematic code and its subcode applied. The first bridge scene is carefully constructed to stand out the confrontation of Chihiro (with Haku) and the bathhouse. The bathhouse is not just a building, it represents the powerful witch, Yubaba, yet to appear on the scene, and functions as an antipode to Chihiro. In each shot, every subcode within the codes of framing, direction, angle, color, lighting and movement is used to maximize the contrast between the dominant bathhouse and the feeble 10-year-old girl. In Spirited Away, the subcodes within each cinematic ode are constantly competing and displacing each other to augment the antithesis between the characters and develop the narrative. As Metz's argument that film constitutes a quasi-linguistic practice as a pluricodic medium, Spirited Away communicates with the spectators with the combination and displacement of these cinematic codes and subcodes.

• Geophysics and Geophysical Exploration
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• v.12 no.1
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• pp.85-98
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• 2009

The tau-p inversion algorithm is widely employed to generate starting models with most computer programs, which implement refraction tomography. This algorithm emphasises the vertical resolution of many layers, and as a result, it frequently fails to detect even large lateral variations in seismic velocities, such as the decreases which are indicative of shear zones. This study demonstrates the failure of the tau-p inversion algorithm to detect or define a major shear zone which is 50m or 10 stations wide. Furthermore, the majority of refraction tomography programs parameterise the seismic velocities within each layer with vertical velocity gradients. By contrast, the Generalized Reciprocal Method (GRM) inversion algorithms emphasise the lateral resolution of individual layers. This study demonstrates the successful detection and definition of the 50m wide shear zone with the GRM inversion algorithms. The existence of the shear zone is confirmed by a 2D analysis of the head wave amplitudes and by numerous closely spaced orthogonal seismic profiles carried out as part of a later 3D refraction investigation. Furthermore, an analysis of the shot record amplitudes indicates that a reversal in the seismic velocities, rather than vertical velocity gradients, occurs in the weathered layers. The major conclusion reached in this study is that while all seismic refraction operations should aim to provide as accurate depth estimates as is practical, those which emphasise the lateral resolution of individual layers generate more useful results for geotechnical and environmental applications. The advantages of the improved lateral resolution are obtained with 2D traverses in which the structural features can be recognised from the magnitudes of the variations in the seismic velocities. Furthermore, the spatial patterns obtained with 3D investigations facilitate the recognition of structural features such as faults which do not display any intrinsic variation or 'signature' in seismic velocities.