• Korean Journal of Acupuncture
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• 제33권3호
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• pp.131-138
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• 2016

Objectives : To assess and compare the effectiveness of acupuncture treatment of depression in Cancer patient's Home Caregivers. Methods : Total 60 cases in Cancer patient's Home Caregivers, who fulfilled the study's eligibility criteria, were recruited and observed(N=40). The individuals were assigned into two groups, the Acupuncture group(N=20) and Control group(N=20). Changes in their Hamilton Depression rating Scale indices, were statistically compared before and after treatment in order to investigate the effectiveness of treatment. Results : 70% Home Caregivers were female and 30% were male, half of the Home Caregivers was patient's spouse or partner and employee. After 6 weeks, Acupuncture group seems to show reduction in the Hamilton Depression Rating Scale. On the other hand after 8 weeks Control group do not show reduction in the Hamilton Depression rating Scale. Conclusions : The results suggest that acupuncture treatment may provide short-term relief of depressive symptoms in Home Caregivers for Cancer patients. Findings from this non-randomized trial should be interpreted with caution.

• Human Ecology Research
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• 제54권5호
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• pp.551-564
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• 2016

This study examined the causal relationship between a mothers' depression and the emotional problems of their preschool-aged children as indicated by anxiety, depression and emotional reactivity. We analyzed data from 1,528 mothers and their children from the Panel Study of Korean Children (PSKC) collected when the children were 4 years old and 5 years old. Autoregressive cross-lagged modeling was conducted using AMOS ver. 23.0 to investigate the longitudinal reciprocal effects between mothers' depression and children's emotional problems. The results indicated that both mothers' depression and children's emotional problems were relatively stable between the ages of 4 to 5. There were significant cross-lagged effects from the mothers' depression to children's emotional problems and from children's emotional problems to mothers' depression. Mothers reported higher levels of depression when the children were 4 years old and the children showed more anxiety, depression and emotional reactivity when they were 5 years old. Emotional problems when the children were 4 predicted greater depression among mothers 1 year later. We also examined the group difference (between boys and girls) in the study model. Gender differences were not statistically supported. The results suggested that early assessment and intervention for mothers' depression and children's emotional problems are essential for a healthy mother-child relationship and later child outcomes.

• 재활치료과학
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• 제8권3호
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• pp.57-68
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• 2019

목적: 신체활동과 인지운동, 사회적 상호작용을 혼합한 단기 집단 복합중재가 75세 이상의 고령 정상 노인의 인지기능과 우울 수준에 미치는 영향을 알아보고자 하였다. 연구방법: 본 연구 설계는 단일 집단 사전-사후 설계(one group pretest-posttest design)로 중재는 회당 70분, 주 1회, 총 4회기 동안 실시하였다. 중재 전과 후의 인지기능과 우울 수준, 신체기능의 변화를 비교하기 위해서 치매 선별용 간이 정신상태검사(Mini-Mental State Examination-Dementia Screening; MMSE-DS)와 단축형 노인우울척도(Short Form for Geriatric Depression Scale; SGDS), 버그균형척도(Berg Balance Scale; BBS)를 사용하였다. 결과: 75세 이상의 고령 정상노인에게 집단 복합중재를 적용한 후 인지기능은 통계적으로 유의미한 향상이 있었고(p<.01), 우울 수준은 통계적으로 유의미한 감소가 있었다(p<.05). 균형수준도 중재 전$46.83{\pm}9.11$점에서 중재 후 $48.08{\pm}7.00$점으로 평가점수의 증가는 있었으나, 통계적으로 유의미하지는 않았다(p>.05). 결론: 신체활동과 인지운동, 사회적 상호작용을 혼합한 단기 집단 복합중재는 75세 이상의 고령 정상노인의 인지기능의 저하를 늦추고 우울수준을 감소시키는데 유의한 효과가 있었다. 본 연구는 정상노인들의 치매, 우울 예방을 위한 중재에 있어서 보다 체계적인 중재를 제공하기 위한 근거를 제시한다는 점에 의의가 있다. 향후 연구에서는 작업치료사에 의한 전문적인 치료에 대한 효과연구와 실험군-대조군 연구를 통해 효과입증이 이루어져야 할 것이다.

• Biomolecules & Therapeutics
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• 제28권3호
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• pp.282-291
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• 2020

Inhaled solvents such as toluene are of particular concern due to their abuse potential that is easily exposed to the environment. The inhalation of toluene causes various behavioral problems, but, the effect of short-term exposure of toluene on changes in emotional behaviors over time after exposure and the accompanying pathological characteristics have not been fully identified. Here, we evaluated the behavioral and neurochemical changes observed over time in mice that inhaled toluene. The mice were exposed to toluene for 30 min at a concentration of either 500 or 2,000 ppm. Toluene did not cause social or motor dysfunction in mice. However, increased anxiety-like behavior was detected in the short-term after exposure, and depression-like behavior appeared as delayed effects. The amount of striatal dopamine metabolites was significantly decreased by toluene, which continued to be seen for up to almost two weeks after inhalation. Additionally, an upregulation of serotonin 1A (5-HT_1A) receptor in the hippocampus and the substantia nigra, as well as reduced immunoreactivity of neurogenesis markers in the dentate gyrus, was observed in the mice after two weeks. These results suggest that toluene inhalation, even single exposure, mimics early anxiety-and delayed depression-like emotional disturbances, underpinned by pathological changes in the brain.

• 기본간호학회지
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• 제15권3호
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• pp.360-370
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• 2008

Purpose: This study was done to identify factors (pain stress, perceived stress, pain disability, fatigue, depression) strategies used by elders to cope with pain based on their type of pain belief. Method: Data were collected from 314 elders in community settings in Seoul from September to December of 2007. Cluster analysis, t-test, and ANOVA were used to analyze data. Result: The types of pain belief were classified as the following groups: Self-blame, Enduring & Mysterious, and Short-term & Understandable. Perceived stress (t=2.36, p=.02), social support (t=2.24, p=.03), extent of pain relief (t=2.39, p=.02), and duration of pain relief (t=2.09, p=.04) were important factors for active and passive coping in the Self-blame group. Pain stress (t=2.39, p=.01) and depression (t=-3.99, p=.00) were significantly related to the active coping in the Enduring & Mysterious group. Perceived stress (t=2.55, p=.01) was an important factor in the passive coping in the Short-term & Understandable group. Conclusion: Considering different types of pain belief in elders and factors that are significantly related to different coping strategies, future nursing interventions should be population specific to encourage active coping strategies and to decrease passive coping strategies.

• Journal of Korean Biological Nursing Science
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• 제24권2호
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• pp.86-94
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• 2022

Purpose: Patients experiencing chemotherapy-induced peripheral neuropathy (CIPN) apply various palliative care as well as drugs in their daily life to alleviate symptoms. There is a need to identify the influence of these efforts and patients' psychosocial status on the relief of CIPN symptoms. This short-term prospective study investigated how prescription drugs, non-pharmacological behaviors (exercise, massage, and heat therapy), and psychological states (social support, depression, and anxiety) affected CIPN symptoms. Methods: Participants scheduled to receive postoperative platinum or taxane-based chemotherapy were enrolled consecutively. CIPN was measured with the Neurotoxicity-12 subscale of the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity-12 instrument. Data were collected three times during the 4 or 5 cycles of chemotherapy. Results: At the end of the 2nd chemotherapy cycle, 93.1% of participants reported CIPN symptoms. Multiple regression analyses showed that a heat therapy (β= -.34, p< .001), massage (β= -.21, p= .012), and walking 5 times or more per week (β= -.26, p= .021) provided relieve for CIPN symptoms. Depression (β= .19, p= .027) significantly exacerbated CIPN symptoms. Conclusion: These results suggested that a comprehensive management program that includes walking, heat therapy, massage, and mood therapy should be encouraged. Moreover, patients should be educated at chemotherapy initiation to understand appropriate interventions that can relieve CIPN symptoms.

• 지역사회간호학회지
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• 제27권1호
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• pp.1-8
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• 2016

Purpose: The purpose of this study was to examine the depression and cognitive function of community-dwelling older adults. Methods: 243 aged over 65 in Won-Ju in South Korea participated in this study. Data were collected from April to June 2013 through interviews. This study utilized the Geriatric Depression Scale Short Form, the Korean version of MMSE-DS (MMSE for Dementia Screening), and infirmity testing for basic health status. Descriptive statistics, ${\chi}^2$, t-test, ANOVA, $Scheff{\acute{e}}^{\prime}s$ test, and Pearson's correlation coefficient were used. Results: 75.3% of the participants belonged to the depression group, and the prevalence of cognitive impairment was 17.3%. There were significant differences in depression and cognitive function according to gender, educational level, type of insurance, subjective health, frailty, and whether to be a client of home care service. The level of depression was significantly higher and the level of cognitive functions was significantly lower in older adults in home care services than in community-dwelling older adults. Conclusion: This study is meaningful in that it included older adults in home care services to provide information to develop effective prevention programs for improving cognitive functions. The results of this study can be used to develop future community prevention and intervention.

• 근관절건강학회지
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• 제25권3호
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• pp.167-175
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• 2018

Purpose: The aim of this study was to test the effects of passive exercise on upper extremities muscle spasticity, finger edema, and depression for chronic stroke patients. Methods: A non-equivalent pretest-posttest design was employed for this study. The subjects were 30 elderly patients who were hospitalized to treat chronic stroke. 15 patients were assigned to the experimental and control groups respectively. Passive exercise for 20 minutes per day, five days a week for 8 weeks (total 40 times) was provided for the experimental group. Outcome measurements included manual spasticity test to measure upper extremities' muscle spasticity, the ring measurement method for finger edema and the Korean version of Short-form Geriatric Depression Scale (SGDS-K) for depression. Results: The upper extremities' muscle spasticity (Z=-2.52 p=.012) and the degree of depression (F=5.56, p=.006) in the experimental group were significantly reduced compared to those of the control group. But the degree of finger edema did not significantly differ between the two groups (F=1.46, p=.240). Conclusion: Passive exercise for upper extremities should be encouraged for elderly patients with chronic stroke to enhance the upper extremities' functional capacity as well as depression.

• 성인간호학회지
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• 제29권1호
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• pp.87-97
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• 2017

Purpose: The purpose of this study was to investigate the relationship among sleep quality, heart rate variability (HRV), fatigue, depression, and anxiety reported by Korean adults. Methods: A cross-sectional study of 208 adults aged 20~60 years was conducted using a short-term HRV analysis and self-reported questionnaires of Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale, Beck Depression Inventory, and State Trait Anxiety Inventory. Results: Subjects with good sleep quality (PSQI $score{\leq}5$) had higher HRV total power (t=2.03, p=.043) and high-frequency (t=2.04, p=.043) with lower fatigue (t=-4.08, p<.001), depressive mood (t=-3.66, p<.001), and trait anxiety (t=-3.84, p<.001) than subjects with poor sleep quality. Poor sleep quality was negatively correlated with HRV total power (r=-.17, p=.016), high-frequency (r=-.14, p=.049), and positively fatigue (r=.39, p<.001), depression (r=.44, p<.001), state anxiety (r=.23, p=.001) and trait anxiety (r=.34, p<.001). Conclusion: The results indicated that sleep quality is correlated with HRV which reflects the activities of the autonomic nerve system, fatigue, depression, and anxiety in adults.

• 지역사회간호학회지
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• 제20권1호
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• pp.12-22
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• 2009

Purpose: This study was done to investigate factors associated with depression and quality of life (QoL) among the community-dwelling elderly. Methods: This study used a descriptive correlational research design. The subjects were 730 elders aged over 65 living in D district of Daegu. Data were collected using questionnaires for 30 days in April, 2007. The research instruments utilized in this study were a physical function scale of long-term care insurance system, Geriatric Depression Scale Short Form Korea Version (GDSSF-K), and Korean Quality of Life Scale (KoQoLs). The collected data were analyzed by descriptive statistics, t-test, ANOVA, Duncan, stepwise multiple regression, and Spearman correlation. Results: The mean age of the subjects was 72.6, and 68.8% and 57.9% of subjects were, respectively, female and living alone. 12.3% of variance in depression was explained by age, education, economic status, subjective health, alcohol consumption, condition of teeth, and fall experience. 18.2% of variance in QoL was explained by economic status, number of diseases, condition of teeth, incontinence, paralysis, and IADL. Economic status and condition of teeth were contributing factors to depression and QoL of the elderly. Conclusion: Findings of this study may be useful in understanding the health status of the community-dwelling elderly and developing more regionally specific health promotion strategies.