• Biomolecules & Therapeutics
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• v.9 no.2
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• pp.125-130
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• 2001

Shin-Ki-Hwan (Shen-Qi-Wan, SKH), Bo-Jung-Ik-Ki-Tang (Bu-Zhong-Yi-Qi-Tang, BJIKT), and Sa-Mul-Tang (Si-Wu-Tang, SMT) have been used for various kinds of deficiency syndromes, such as 'yang', 'qi', and 'blood', respectively. The objects of this study were to determine the effects of water extracts of three different kinds of traditional Chinese medicine (TCM), SKH, BJIKT, and SMT, on the anxiolytic activities in the elevated plus-maze test and to clarify the differences among 'yang', 'qi', and 'blood'. The water extracts of SKH, BJIKT, and SMT were orally administered to male SD rats, at 1.0 g/kg for 10 days. All rats were subjected to behavioral tests for the anxiolytic activity at 10 days. SKH, for the benefiting 'yang'agents, significantly increased the ratio of open arms entry to the total arms entry and time spent in the open arms (p<0.05), suggesting anxiolytic effect. However, both BJIKT and SMT decreased the ratio of open arms entry to the total arms entry and increased times spent in the closed arms (p<0.05). From these findings, it can be speculated that SKH only exhibits anxiolytic effect and that the different anxiolytic effects in the elevated plus-maze test may be come from the meanings of 'yang', 'qi', and 'blood'in oriental diagnostics though the cases are restricted.

• The Journal of Internal Korean Medicine
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• v.19 no.1
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• pp.271-290
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• 1998

As a result of investigating the cases of applying Yuk-mi-ji-hwang-tang-kakambang(六味地黃湯加減方) to treating dementia, the following results are obtained. 1. Yuk-mi-ji-hwang-tang-kakambang(六味地黃湯加減方)is applied to anapladementia. 2 Yuk-mi-ji-hwang-tang-kakambang(六味地黃湯加減方) is also applied to treating the dementia due to congenital weakness and defficiencies of the Liver and Kidney, the Spleen and Kidney. 3. To cure congenital weakness, Yuk-mi-ji-hwang-tang(六味地黃湯), Jwa-kwi-hwan(左歸丸), Bo-sin-ik-su-tang(補腎益髓湯) and Chil-bok-eum-kakam(七福飮加減) which can bo-sin-ik-jeong(補腎益精) sung-noi-ik-ji(醒腦益智), for the defficiencies of liver and kidney, Jwa-kwi-hwan-kakam(左歸丸加減), Woo- kwi-eum-kakam(左歸飮加減) and Ki-kuk-ji-hwang-tang-hap-jng-ji-tang-kakam(杞菊地黃湯合定智湯加減) which can bo-ik- kan-sin(補益肝腎) jeon-jeong-gun-noi(塡精健腦) and for the defficiencies of spleen and kidney, Hwan-so-dan-kakam(還少丹加減) and Kum-kwe-shin-ki-hwan-kakam(金궤腎氣丸加減) which can bo-sin-gun-bi(補腎健脾) ik-gi-sang-jeong(益氣生精) gun-noi-sang-su(健腦生髓) 4. Won-Ji(遠志) and Suk-chang-po(石菖蒲) which can sung-sin-ga-gu(醒神開竅) are added to yuk-mi-ji-hwang-tang(六味地黃湯).

• Journal of Acupuncture Research
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• v.24 no.3
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• pp.29-38
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• 2007

Objectives : The purpose of this study was to investigate the effects of $Taegye(KI_3)$ acupuncture and acupuncture with twirling method on the blood pressure, cardiomegalic index, plasma levels of renin and atrial natriuretic peptide in hypertensive RAT induced by two kidney one clip (2KIC). Methods : This study was conducted on one control group and four experimental groups. Control group that had no treatment, Tail group that took tail acupuncture, K-0 group that took $KI_3$ acupuncture, K-6 group that took $KI_3$ acupuncture with 6 turns of twirling method, K-9 group that took $KI_3$ acupuncture with 9 turns of twirling method. Results : Blood pressure was decreased significantly after $KI_3$ acupuncture. Cardiomegalic index decreased significantly after $KI_3$ acupuncture. Plasma levels of renin was decreased significantly after $KI_3$ acupuncture and acupuncture with 9 turns of twirling method Ⅳ. Plasma levels of atrial natriuretic peptide was increased significantly after $KI_3$ acupuncture. Conclusions : These results suggest that blood pressure was decreased significantly after $KI_3$ acupuncture in hypertensive RAT induced by two kidney one clip (2K1C).

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• v.11 no.1
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• pp.108-112
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• 2006

• Korean Journal of Social Welfare
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• v.27
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• pp.153-179
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• 1995

• Proceedings of the PSK Conference
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• 2002.04a
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• pp.140.1-140.1
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• 2002

• Korean Journal of Acupuncture
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• v.23 no.2
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• pp.47-57
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• 2006

Objectives: The aim of the present study was to widen a clinical use by investigating literatures about the acupoint of Pu-ryu(KI7) and Um-gok(KI10) concerning Kidney-Eum(vital essence of the kidney) and Kidney-Yang(vital function of the kidney). Methods: We investigated the first literature about $Pu-ryu(KI7)\;{\cdot}\;Um-gok(KI10)$ and a second name, a location and a characteristic of them. We made a comparative study about the chief virtue and combination of $Pu-ryu(KI7)\;{\cdot}\;Um-gok(KI10)$. Results: Pu-ryu(KI7) is the 7th acupoint of Kidney Meridian of Foot Soeum(少陰), which reinforces a meridian of belonging and has the efficacy of warming the Kidney Yang, clearing heat, excreting dump and regulating water passage. Um-gok(KI10) is the 10th acupoint of Kidney Meridian of Foot Soeum(少陰), which has the virtue of nurishing the Liver and Kidney Eum, promoting lower heater and marinating the free flow of Gi Conclusions: The chief virtue of Pu-ryu(KI7) is to remove edema due to disturbance in Gi activity by dificiency of Kidney-Yang because of warming Yang to induce diuresis. To Um-gok(KI10), it is to treat instability of Kidney-Gi by Eum dificiency of the Liver and Kidney because of nurishing the Liver and Kidney Eum.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.4
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• pp.88-96
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• 2014

Objectives: The purpose of this study is to evaluate the effects of Kamikubi-hwan on menopausal disorder patients. Methods: We surveyed 21 menopausal disorder patients was administered Kamikubi-hwan. The patients of menopausal disorder was estimated twice with Kupperman's index (KI) and Stress response inventory (SRI). Results: After treatment, the mean of KI and SRI score were decreased. Symptoms of menopausal disorder were decreased. Conclusions: This study shows that Kamikubi-hwan is significantly effective on menopausal disorder patients.

• Proceedings of the KSRS Conference
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• 2009.03a
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• pp.222-222
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• 2009

• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.895-898
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• 2005