• 제목/요약/키워드: Sexual development

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Molecular Genetics of Emericella nidulans Sexual Development

  • Han, Kap-Hoon
    • Mycobiology
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    • 제37권3호
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    • pp.171-182
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    • 2009
  • Many aspergilli that belongs to ascomycetes have sexuality. In a homothallic or self-fertile fungus, a number of fruiting bodies or cleistothecia are formed in a thallus grown from a single haploid conidia or ascospores. Genome-sequencing project revealed that two mating genes (MAT) encoding the regulatory proteins that are necessary for controlling partner recognition in heterothallic fungi were conserved in most aspergilli. The MAT gene products in some self-fertile species were not required for recognition of mating partner at pheromone-signaling stage but required at later stages of sexual development. Various environmental factors such as nutritional status, culture conditions and several stresses, influence the decision or progression of sexual reproduction. A large number of genes are expected to be involved in sexual development of Emericella nidulans (anamorph: Aspergillus nidulans), a genetic and biological model organism in aspergilli. The sexual development process can be grouped into several development stages, including the decision of sexual reproductive cycle, mating process, growth of fruiting body, karyogamy followed by meiosis, and sporulation process. Complicated regulatory networks, such as signal transduction pathways and gene expression controls, may work in each stage and stage-to-stage linkages. In this review, the components joining in the regulatory pathways of sexual development, although they constitute only a small part of the whole regulatory networks, are briefly mentioned. Some of them control sexual development positively and some do negatively. Regarding the difficulties for studying sexual differentiation compare to asexual one, recent progresses in molecular genetics of E. nidulans enlarge the boundaries of understanding sexual development in the non-fertile species as well as in fertile fungi.

Promotion of Asexual Development and Inhibition of Sexual Development of Aspergillus nidulans by Short-Chain Primary Amines

  • Song, Myung-Hoon;Kuppusamy Selvam;Park, Chang-Jun;Jahng, Kwang-Yeop;Han, Dong-Min;Chae, Keon-Sang
    • Journal of Microbiology
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    • 제40권3호
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    • pp.230-233
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    • 2002
  • Effects of short-chain primary amines on Aspergillus nidulans development were analyzed. Propylamine induced asexual development and inhibited sexual development. Even on medium containing lactose as the sole carbon source, on which little conidial heads are formed and sexual structures are formed preferentially, or when sexual development was induced, propylamine induced asexual development and inhibited sexual development. These effects of propylamine seemed to be due to accumulation of mRNA of the brlA gene, which has been identified as a positive regulator of asexual development, and due to the reduction of the veA mRNA level. The veA gene has been identified as an activator of sexual development and also as an inhibitor of asexual development. Other primary amines, methylamine and ethylamine, showed identical effects on development where short-chain primary amino also promoted asexual development and inhibited sexual development.

사춘기 아동의 성적성숙도와 혈압수준 (The Blood Pressure Level and Sexual Maturity in the Children at Puberty)

  • 김규상;이순영;서일;남정모;지선하
    • Journal of Preventive Medicine and Public Health
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    • 제26권3호
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    • pp.347-358
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    • 1993
  • The purpose of this study is to analyze the relationship between the blood pressure level and their sexual maturity and physical growth in the children at puberty. For this purpose, we estimated the blood pressure, physical growth and sexual maturity of the boys of 335 and girls of 373 who are in the middle schools which are located in Kangwha County, Kyungki-Do. Both systolic and diastolic pressure were measured twice. Such physical growth as height, body weight, skin fold thickness, waist circumference, hip circumference and arm circumference were measured. The sexual maturity was estimated according to the classification of Tanner's 5-phase-sexual-maturity : in boys, their pubic hair development phase : in girls, their pubic hair and breast development phase and the menstrual experience. In the phase of the pubic hair development, the boy's sexual maturity was distributed into this; the 1 st 56.4%, the 2nd 29.3%, the 3rd 9.9%, the 4th 4.1% and the 5th 0.3%. While the girls sexual maturity was distributed into this the 1st 20.5%, the 2nd 34.9%, the 3rd 30.6% the 4th 12.6% and the 5th 1.3% in the phase of the pubic hair development, and the 1st 0.8%, the 2nd 13.7%, the 3rd 36.2%, the 4th 18.8% and the 5th 30.5% in the phase of the breast development. This indicated that the girls sexual maturity was higher than those of the boys. The girls menstrual experience rate accounted to the 58.2%. In order to see the relationship between the children's sexual maturity and blood pressure level, we regress blood pressure level on physical growth (i.e., height, BMI) and sexual maturity. Sexual maturity in treates as dummy variables. As the resulf of this analysis, the boys' sexual maturity has nothing to do with the blood pressure either systolic or diastolic. But the girl's systolic pressure was statistically significant ; the 9% of the physical growth, the 5% of the pubic hair development and the 4% of the breast development in sexual maturity was explained. In the girls' diastolic pressure, only their pubic hair development was statistically significant ; the 7% of the physical growth and the 7% of the pubic hair development in the diastolic was explained and the 5% of the physical growth in the diastolic Korotokoff phase IV and the 2% of the pubic hair development in the diastic Korotokoff phase was explained, especially, the girls exprienced menstruation, their systolic and diastolic pressure were significantly high (P<0.01). Conclusively, in the first grade children attending middle schools who are in the early process of the sexual development, the sexual maturity was not related to blood pressure level, on the other hand, the blood pressure level of the girls who are more sexual development than those of the boys' have something to do with sexual maturity and physical growth.

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Effects of Sexual Abuse Prevention Education Program on Sexual Knowledge and Attitude among Elementary School Students

  • Lee, Yun Hee;Hwang, Won Ju
    • 지역사회간호학회지
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    • 제27권2호
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    • pp.132-143
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    • 2016
  • Purpose: The purpose of this study was to investigate the effects of sexual abuse prevention education program linked to elementary physical and psychological development on sexual knowledge and attitude. Methods: The participants were the elementary school students of fifth and sixth grades in S city, South Korea (experimental, comparison, and control group=96, 96, and 74, respectively). The experimental group received sexual abuse prevention education linked physical and psychological development, 6 sessions (3 sessions are physical and psychological development educations and 3 other sessions are sexual abuse prevention educations). The comparison group received sexual abuse prevention educations, 3 sessions (the same curriculum of the experimental group). The control group didn't receive any sexual education. The data were analyzed by $x^2$ test and t-test, and ANOVA using the SPSS program. Results: The experimental group showed significantly better sexual knowledge and attitude than the comparison and control group. Conclusion: Sexual abuse prevention education program linked physical and psychological development is required for elementary school students, to improve the sexual knowledge and attitude.

초등학교 고학년 학생의 성교육 요구 내용 분석 (Analysis of Needs for Sexual Education in Primary School Children)

  • 양순옥;정금희;한영란
    • Child Health Nursing Research
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    • 제7권1호
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    • pp.5-20
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    • 2001
  • The purpose of this study was to analyze and identify the higher-grade primary school children's needs for sexual education. We got the data with open question from 481 children from March to July 1999. We analyzed them according to the framework suggested by the Sex Information and Education Council of USA. The framework involves the six domains such as human development, relationship, personal skills, sexual behavior, sexual health, and society & culture. In the analysis of need for sexual education according to domain, need for human development was highest (79.2 %), after that followed society & culture (8.3 %), sexual health (5.8%), sexual behavior (3.6%), and relationships (3.1%). There was no need for personal skills. By topics, there were needs for puberty (38.0%), reproduction (32.5%), gender roles (6.0%), body image (4.9%), sexual abuse (2.4%) and reproductive health (2.4%). Girls and boys all mostly wanted to know human development 41.0 % and 38.2 % each. Society & culture (3.4 %), sexual behaviour (2.7%), sexual health (2.6%), relationship (2.4%) were domains selected by boys. Girls wanted to know society & culture (4.9%) and 'sexual health (3.2%). Comparing by grade, fourth, fifth and sixth grade children are commonly interested in development, society & culture. Fourth grade children scarcely show attention on the relationship, sexual behaviour and sexual health; meanwhile sixth grade children would like to know sexual behaviour and sexual health. When their grade became higher, they would like to know more precise, concrete and deep information. We suggest that the textbook/guidebook for sexual health for the higher-grade primary school children should be developed considering the sex and grade.

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Sexual Intercourse and Its Correlates Among School-aged Adolescents in Indonesia: Analysis of the 2015 Global School-based Health Survey

  • Rizkianti, Anissa;Maisya, Iram Barida;Kusumawardani, Nunik;Linhart, Christine;Pardosi, Jerico Franciscus
    • Journal of Preventive Medicine and Public Health
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    • 제53권5호
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    • pp.323-331
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    • 2020
  • Objectives: This study aimed to determine the prevalence and correlates of sexual intercourse among junior secondary and high school students in Indonesia from the 2015 Global School-based Health Survey (GSHS). Methods: The survey was conducted among 11 110 students from 75 schools in Indonesia using a self-administered questionnaire. Univariate and multivariate analyses were conducted to explore associations between sexual intercourse and socio-demographic variables, substance use, mental distress, and protective factors. Results: Overall, 5.3% of students reported having ever had sex (6.9% of boys and 3.8% of girls). Of students who engaged in sexual intercourse, 72.7% of boys and 90.3% of girls had an early sexual debut (before reaching the age of 15) and around 60% had multiple sex partners. Sexual intercourse was associated with gender, school grade, smoking, alcohol consumption, drug use, suicidal ideation, truancy, peer support, and parental supervision. Conclusions: These findings indicate a pressing need to develop more comprehensive sexual health education in the national curriculum. An effective strategy should also address other risky behaviours.

Aspergillus nidulans에 있어서 무성분화(無成分化)의 억제조건(抑制條件)과 이를 이용(利用)한 유성분화결손(有性分化缺損) 돌연변이주(突然變異株)의 대량분리(大量分離) (Inhibitory Conditions of Asexual Development and their Application for the Screening of Mutants Defective in Sexual Development)

  • 한동민;한유정;이영훈;장광엽;장승환;채건상
    • 한국균학회지
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    • 제18권4호
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    • pp.225-232
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    • 1990
  • 몇몇 배양조건이 유성 또는 무성분화에 미치는 영향을 조사하여, 유성분화 결손 돌연변이주를 분리하기 위한 효율적인 조건을 찾고자 하였다. 무성분화는 억제하며, 유성분화는 촉진시키는 여러조건중 Casein hydrolysate를 첨가한 최소배지에 밀봉 배양하는 것이 가장 효율적인 조건으로 선택되었다. 접종 후 20시간 이전에 밀봉하고 계속 배양하면, 유 무성분화 모두가 억제되나, 밀봉 후 20시간 정도 후에 밀봉을 해제하면 유성분화만이 진행되었다. 이러한 성질을 이용하여 유성분화과정에 이상이 일어난 돌연변이주를 대랑 분리해 냈었으며, 이들의 분화양상에 따라 크게 3 group : NSD(never in sexual development), BSD(block in sexual development), ASD(abnormal in sexual development)으로 분류하였다. NSD 돌연변이주는 $H{\ddot{u}}lle$ cell이나 cleistothecia 등의 유성생식기관을 전혀 생성하지 못하였고, BSD 돌연변이주는 $H{\ddot{u}}lle$ cell, cleistothecia, crozier, asci 또는 ascospore 형성 중 어느 과정에서 중단되어 분화가 끝가지 진행되지 못하였으며, ASD 돌연변이주는 유성분화의 최종단계가지 진행은 되지만 유성생식 기관의 생성시기나 양이 야생형과 현저하게 차이를 보였다.

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미혼모 성 건강교육 프로그램 개발 및 적용 (Development and Application of Sexual Health Education Program for Unmarried Mothers)

  • 정금희;김신정;양순옥
    • 여성건강간호학회지
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    • 제10권3호
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    • pp.252-260
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    • 2004
  • Purpose: This study was done to develop a sexual health education program for unmarried mothers that were intended to provide the correct sexual knowledge, to help them establish positive sexual perception and to improve sexual health. The program was applied and its effect was evaluated. Method: One group pretest-posttest quasi-experimental research design was applied to evaluate the effect of a sexual health education program unmarried mothers. The research team developed a 34 hour program of 16 units, where the basic schemes were human development, relationships, personal skills, sexual behavior, sexual health, and society & culture. We applied the program to 32 unmarried mothers in the Institute for unmarried mothers in Gangwon-do, Korea from April 19, 2004 to June 14, 2004. Result: After the application of an 8 week sexual health education program, the subjects significantly showed a better perception of self-efficiency, self-esteem, sexual knowledge and sexual behavior than before the program. Conclusion: The sexual health education program for unmarried mother in this study was effective on improving sexual perception and promoting sexual health behavior.

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초등학생의 성 성숙, 성 성숙 태도 및 신체 자존감 (Sexual Maturation, Attitudes towards Sexual Maturity, and Body Esteem in Elementary-School Children)

  • 박선아;최은영;이은희;변미경;이병주;정계아
    • 여성건강간호학회지
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    • 제24권2호
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    • pp.219-228
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    • 2018
  • Purpose: The purpose of this study is to evaluate sexual maturation, attitudes toward sexual maturity, and body esteem in the sexual development of Korean elementary-school boys and girls. Methods: A descriptive cross-sectional study was conducted with 399 fifth and sixth graders (192 boys and 207 girls). The data were analysed with a $x^2$ test, t-test, and Pearson correlation coefficients. Results: Among the 207 girls, 70.5% had pubic hair growth, 68.1% had breast development, and 56.0% had a menstrual period. In boys, 59.4% of the 192 subjects experienced the development of external genitalia and 52.6% had pubic hair growth. Sexual maturation was related to grade (boys, t=7.07, p=.008; girls, t=12.76, p<.001), age (t=-2.20, p=.030; t=-4.11, p<.001), height (t=-5.16, p<.001; t=-7.52, p<.001), and weight (t=-2.89, p=.004; t=-5.19, p<.001) in both boys and girls. Girls were more likely to have sexual maturity than boys ($x^2=22.29$, p<.001). Boys showed more positive attitudes toward sexual maturity (t=2.10, p=.036) and higher body esteem (t=2.12, p=.035) than girls. Conclusion: This study shows that sexual maturation, attitude toward sexual maturity, and body esteem in sexual development differ between boys and girls. The findings indicate that it is necessary to develop a tailored sex-education program according to the sex of elementary-school children.

성 성숙 속도가 다른 사춘기 아동의 성장 발달과 식행동 비교 (Comparisons of Dietary Behaviors and Growth Development with Different Sexual Maturation Velocities in Children of Pubertal Age)

  • 이유신;이심열
    • 동아시아식생활학회지
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    • 제23권5호
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    • pp.519-532
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    • 2013
  • The purpose of this study was to make a comparative analysis of dietary habits, snacks, eating out and fast-food intake between students with a relatively early sexual maturity and others with a relatively late sexual maturity in a bid to grasp the impact of dietary behaviors on sexual maturity. The subjects in this study were 565 boys and girls who resided in Seoul and Gyeonggi province. They included fifth- and sixth-grade school children and seventh-grade middle school students. To classify the selected students according to the level of sexual maturity, the students of the same month age were divided into two groups in consideration of the stage of their sexual maturity and that of the other age groups. The early mature group was significantly taller and weighed more than the late mature group irrespective of gender. According to Tanner stages, the boys of the early mature group reached a 3.03 stage of sexual maturity when the sexual organs were taken into account, and those of the late mature group reached a 1.50 stage of sexual maturity. The girls of the early mature group reached a 3.43 stage of sexual maturity on the basis of breast, and those of the late mature group reached a 2.73 stage of sexual maturity. Concerning eating out, the early mature group ate out more frequently than the late mature group. In regard to snacks, the early mature group had a snack more often. The findings of the study indicated that there were differences in physical development and some dietary behaviors according to sexual maturity. The early mature group had a snack and ate out relatively more often than the late mature group, which showed that some dietary behaviors had an impact on the sexual maturity of the teens who arrived at the age of puberty.