• 대한가정학회지
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• 제29권1호
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• pp.139-158
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• 1991

The purpose of this study is to investigate the relationship between adult children's perceived interaction pattern with their parents and their marital satisfaction. The subjects are a total of 646 male and female who been married for 3 years or less, living in Seoul, and whose fathers or mothers are still alive. The questionaire, including of attachment, autonomy, marital satisfaction scales, are distributed to collect the data. The main results are as follows: 1. Intimate-Dependent type is 31% each in relation to fathers and mothers. Distant-Independent type is 30% in relation to fathers, 27% in relation to mothers. Balanced type is 21% in relation to fathers, 23% in relation to mothers. Undeveloped type is 18% in relation to fathers, 19% in relation to mothers. 2. there is interaction effect between parental sex and adult children's sex as related to attachment levels, autonomy levels. 3. There is statistically significant difference among attachment-autonomy patterns as related to adult children's marital satisfaction. 4. Attachment and autonomy in relation to fathers and attachment in relation to mothers affect sons' marital satisfaction positively. Attachment in relation to fathers and mothers affect positively to daughters' marital satisfaction.

• 생명과학회지
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• 제16권5호
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• pp.828-833
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• 2006

옥수수 (Zea mays L.) 꽃은 암술 세포사멸과 수술 세포 성장정지 등을 통하여 양성상태에서 단성 상태로 성결정 과정을 완성한다. 본 논문에서는 옥수수 성 결정 동안 세포주기 유전자들의 시간적, 공간적 발현조절을 조사하였다. 세포주기의 양성조절 인자 즉 cyclin A, cyclin B, cyclin dependent kinase A (CDK A), Mad2 유전자들은 성장하는 암술과 수술에서 높게 발현되는 반면 죽어가는 암술과 성장이 정지되는 수술에서는 이들의 발현이 사라졌다. 이와 반대로, Wee1과 CDK inhibitor (CKI) 같은 세포주기 음성 조절유전자들은 야생형 암꽃과 tasselseed2 돌연변이 수꽃의 성장이 정지하고 있는 수술에서 발현이 증가되었지만, 흥미롭게도, 이들 유전자들은 죽어가는 암술세포에서는 발현되지 않았다. 이들 결과들을 통하여 옥수수 성 결정 과정 중에서 암술 세포사멸과 수술세포 성장정지는 세포주기조절과 밀접한 관계가 있으며, 특히 성장이 정지하는 수술과 죽어가는 암술에서의 음성 세포주기 조절 유전자들의 다른 발현양상은 이 둘의 성 결정 메커니즘이 구별 될 것이라고 사료된다.

• 대한의생명과학회지
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• 제20권1호
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• pp.43-47
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• 2014

To understand the effect of prenatal stress on sex-specific changes in embryonic and placental growth, a synthetic glucocorticoid (dexamethasone) was administered intraperitoneally at a dosage of 1 mg/kg body weight (BW) (Dex1) or 10 mg/kg BW (Dex10) to pregnant ICR mice at the gestational days 7.5, 8.5 and 9.5 post coitum (p.c.). Embryos and placentas were then harvested at days 11.5 and 18.5 p.c., and their body weight and size were measured following the determination of sex through PCR using Sry specific primers in tail tissues. As a result, female embryos presented reduced fetal body weight and size in Dex1- and Dex10-treated groups than those of control group at the embryonic day 11.5 p.c. Interestingly, the growth seems to be recovered at day 18.5 as there was no difference in growth between control and dexamethasone treated groups. In the case of males, Dex1 induced a decrease in fetal weight in day 11.5 and this pattern was maintained until day 18.5, whereas their growth was not affected by Dex10 treatment. Placental growth showed similar patterns to fetal growth in both sexes but the extent of reduction was not statistically significant in most cases. Placental weights in Dex1- and Dex10-treated group were decreased significantly in male only. The results imply that the effect of prenatal stress is largely sex dependent due to different strategies for growth and survival in a stressful environment.

• Toxicological Research
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• 제34권3호
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• pp.199-210
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• 2018

Skeletal muscle can be ultrastructurally damaged by eccentric exercise, and the damage causes metabolic disruption in muscle. This study aimed to determine changes in the metabolomic patterns in urine and metabolomic markers in muscle damage after eccentric exercise. Five men and 6 women aged 19~23 years performed 30 min of the bench step exercise at 70 steps per min at a determined step height of 110% of the lower leg length, and stepping frequency at 15 cycles per min. $^1H$ NMR spectral analysis was performed in urine collected from all participants before and after eccentric exercise-induced muscle damage conventionally determined using a visual analogue scale (VAS) and maximal voluntary contraction (MVC). Urinary metabolic profiles were built by multivariate analysis of principal component analysis (PCA) and orthogonal partial least square-discriminant analysis (OPLS-DA) using SIMCA-P. From the OPLS-DA, men and women were separated 2 hr after the eccentric exercise and the separated patterns were maintained or clarified until 96 hr after the eccentric exercise. Subsequently, urinary metabolic profiles showed distinct trajectory patterns between men and women. Finally, we found increased urinary metabolites (men: alanine, asparagine, citrate, creatine phosphate, ethanol, formate, glucose, glycine, histidine, and lactate; women: adenine) after the eccentric exercise. These results could contribute to understanding metabolic responses following eccentric exercise-induced muscle damage in humans.

• 보건행정학회지
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• 제25권4호
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• pp.285-294
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• 2015

Background: Suicide is one of important health problems in Korea. Previous studies showed factors associated with suicide in individual levels. However, suicide was influenced by society that individuals belong to, so it was required to analyze suicide in local levels. The purpose of this study was to analyze the regional disparities of suicide mortality by gender and the association between local characteristics and suicide mortality. Methods: This study included 229 city county district administrative districts in Korea. Age- and sex-standardized suicide mortality and age-standardized suicide mortality (male/female) were used as dependent variables. City county district types, socio-demographics (number of divorces per 1,000 population, number of marriages per 1,000 population, and single households), financial variable (financial independence), welfare variable (welfare budget), and health behavior/status (perceived health status scores and EuroQol-5 dimension [EQ-5D]) were used to represent the local characteristics. We used hot-spot analysis to identify the spatial patterns of suicide mortality and negative binomial regression analysis to examine factors affecting suicide mortality. Results: There were differences in distribution of suicide mortality and hot-spot regions of suicide mortality by gender. Negative binomial regression analysis provided that city county district types (city), number of divorces per 1,000 population, financial independence, and EQ-5D had significant influences on the age- and sex-standardized suicide mortality per 100,000. Factor influencing suicide mortality was the number of divorces per 1,000 population in both male and female. Conclusion: Study results provided evidences that suicide mortality among regions was differed by gender. Health policy makers will need to consider gender and local characteristics when making policies for suicides.

• 가정과삶의질연구
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• 제26권6호
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• pp.71-82
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• 2008

The purpose of this study was to identify factors affecting the purchases of well-being tea drinks based on the analysis of demographic characteristics, well-being oriented consumer behaviors, and consumer consciousness toward well-being tea drinks. The subjects of this study were undergraduates and graduate students in Seoul. The findings were summarized as follows: 1. Well-being oriented consumer behavior patterns were categorized in three factors; non-dietary life, selective dietary life, and regular/temperate behavior and consumer consciousness toward well-being tea drinks were categorized in two factors; habit/ familiarity and health/ economical efficiency. 2. Multiple regression analysis was used for finding out factors affecting the purchases of well-being tea drinks; independent variables were demographic characteristics(sex, monthly average family income and the amount of personal expenditure), well-being oriented consumer behavior factors and consumer consciousness factors toward well-being tea drinks. Weekly purchase frequency of well-being tea drinks was defined as a dependent variable. As a result, the purchases of well-being tea drinks were influenced in order of regular/temperate behavior, the consciousness of health/ economical efficiency, the amount of personal expenditure and the consciousness of habit/ familiarity. Especially, regular/temperate behavior negatively affected the purchases of well-being tea drinks.

• 한국생활과학회지
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• 제16권2호
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• pp.273-283
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• 2007

The purpose of this study was to identify consumption behaviors among children and to examine the differences according to sociodemographic characteristics, factors related to allowance, and parents' consumer socialization function perceived by children. The data were collected from 291 elementary school students in Busan. The results of this study were as follows. First, regarding parents' consumer socialization function perceived by children, the level of child's participation and influence in consumption decision-making was the highest, whereas the level of parent-child communication about consumption was the lowest. Second, consumption behaviors among children were identified into 5 groups: impulsive consumption group, rational allowance management group, friend-dependent purchase group, planned purchase group, and effective goods management group. There were significant difference among them according to child's sex, allowance amount, allowance frequency, parents' guidance about allowance usage, parents' check after allowance usage, and 3 categories of parents' consumer socialization function perceived by children. These results imply that consumer education for parents should be developed and activated to improve consumer socialization function of parents.

• Nutrition Research and Practice
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• 제1권2호
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• pp.79-83
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• 2007

The present study was conducted to document the association between plasma homocysteine levels and the presence of macrovascular angiopathy with food and nutrient intake patterns among patients with Type II diabetes mellitus in Korea. Plasma total homocysteine concentration was analyzed by HPLC-fluorescence detector method in 127 patients with non-insulin dependent diabetes mellitus. Logistic regression analyses were performed respectively to study the association of plasma homocysteine levels with clinical and dietary characteristics and macroangiopathy (MA). The average plasma homocysteine level of patients with MA was $14.2{\mu}mol/l$, which was significantly higher than that of patients without MA ($11.4{\mu}mol/l$). The proportions of patients with MA showed a significant difference, being 32.3% in hyperhomocysteinemic ($>14.0{\mu}mol/l$) patients and 13.5% in others with homocysteine levels lower than $14.0{\mu}mol/l$. Odds ratios for macroangiopathy by tertile increase of plasma homocysteine concentration were 1.633 ($Q_2$) and 4.831 ($Q_3$), when adjusted for age, sex, and cigarette smoking. Patients with MA consumed reduced amounts of vitamin $B_1,\;B_2$, and folate. The results indicate that the plasma homocysteine levels are significantly increased in NIDDM patients who have macroangiopathy. Dietary management such as increased fruits and vegetables and decreased potatoes and starches might be beneficial for the prevention of macroangiopathy in diabetic patients.

• Journal of Nutrition and Health
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• 제32권4호
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• pp.407-418
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• 1999

The purpose of this study was to identify dietary factors related to the incidence of diabetes mellitus in Korea. The study consisted of 165 diabetic patients, male and female, aged 30 to 70 years and 198 healthy persons as controls. Diabetic patients who had been diagnosed with diabetes mellitus for less than five years before the study period were recruited from eight different hospitals located in Seoul, Korea. Socioeconomic status, state of illness, physical activity, food habits and food intake were assessed. Food intake was assessed by food frequency questionnaire method using a 105-food frequency questionnaire developed for diabetic patients. The stress and activity indices of diabetic patients were not significantly different from control, but alcohol consumption and smoking levels were higher in diabetics than controls. Other diseases of male diabetic patients included liver diseases, digestive system diseases, and hypertension, while those of female diabetics were hypertension, neuralgia, arthritis and digestive system diseases. These disease patterns are different from Western countries whose most common complications are hypertension and hyperlipidemia. More irregular and less varied meals were found in the diabetic group compared to the control group, suggesting that diabetic patients have generally undesirable food habits. Otherwise, food and nutrient intake of diabetics did not differ greatly from the control group. It was found that diabetic patients consumed more cereals and less fruit than the control group, and also that male diabetics consumed more alcohol. The carbohydrate : protein : fat energy distribution ratio was 61.7 : 15.8 : 22.5 in male patients and 65.1 : 14.9 : 19.7 in female patients. Discriminant analysis showed that diabetes risk factors differed with sex. In male patients, the important factors were body mass index(BMI), vitamin C intake, family diabetic history and vegetable intake, while in female patients they were BMI, cereals intake, carbohydrate intake, vitamin C intake, stress, food habits and Ca intake. These results show that excessive intake of energy and fat are not the major causal factors in Korean NIDDM. Therefore, the diabetes risk factors of Western countries may not directly apply to Koreans. Mors study is needed to clarify the risk factors of Korean NIDDM.

• Journal of Animal Science and Technology
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• 제49권1호
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• pp.1-8
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• 2007

두 가지 primer 쌍을 동시에 이용한 duplex PCR 기법으로 붉은사슴과 엘크의 유전자 성 판별에 대한 이용가능성을 확인하기 위해 본 연구를 수행하였다. 근본적으로 포유동물의 성 분화는 Y-염색체 상에 암호화되어 있으며 웅성발생에 지배적인 역할을 수행하는 SRY 유전자의 존재 여부에 따라 결정되게 된다. X-, Y- 염색체에 상동인 유전자들 중 하나인 ZFX-ZFY 유전자는 X-, Y- 염색체 상에서 각각 발견된다. 유전자 성 판별에 앞서 붉은사슴의 ZFX-ZFY 유전자의 인트론 9를 포함하는 절편에 대한 염기서열의 특성을 확인하였다. 인트론 9의 길이는 ZFX와 ZFY에서 각각 529, 665-bp로 확인되었다. ZFY 인트론 9에서 전위인자의 일종인 bovine SINE element와 유사한 서열이 관찰되었다. SRY와 ZFX-ZFY 유전자들을 동시에 증폭하는 duplex PCR을 통해 유전자 성 판별을 수행하였고, 암수가 서로 구분되는 증폭 양상을 나타내었다: 암컷에서는 ZFX에서 증폭된 공통의 증폭 산물 하나만이 관찰되었고 수컷은 세 개의 밴드가 관찰되었다(ZFX에 해당하는 공통의 밴드와 ZFY와 SRY에서 증폭된 두 개의 수컷 특이 밴드). 두 가지 유전자에 대한 독립적인 PCR 시험에서 얻은 결과는 duplex PCR에 의해 얻은 결과와 동일한 양상을 나타내었다. 또한 유전자 성 판별의 결과들은 각각의 개체에 대한 표현형적 성판별 자료와 정확히 일치하였다. Y 염색체 특이적인 SRY와 X-, Y- 상동이면서 성적 이형성을 나타내는 ZFX-ZFY 유전자들에 대한 duplex PCR 방법은 붉은사슴과 엘크의 성 판별에 있어 여타 다른 대조시험을 요구하지 않으면서 없이 신속하고 정확한 정보를 제공하는 분석법이 될 것으로 기대된다.