• Journal of Periodontal and Implant Science
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• v.50 no.6
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• pp.368-378
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• 2020

Purpose: Vitamin D deficiency may cause bone loss and increased inflammation, which are well-known symptoms of periodontal disease. This study investigated whether serum 25-hydroxyvitamin D (25(OH)D) levels are associated with periodontal disease status and tooth loss. Methods: Cross-sectional data from 5,405 individuals aged ≥50 years (2,253 males and 3,152 females) were obtained from the 2008-2010 Dong-gu study, a prospective cohort study of risk factors for chronic diseases. Periodontal examinations were conducted to evaluate the number of remaining teeth, the periodontal probing depth (PPD), the clinical attachment level (CAL), and bleeding on probing. The percentages of sites with PPD ≥4 mm and CAL ≥4 mm were recorded for each participant. The severity of periodontitis was classified using the Centers for Disease Control and Prevention and the American Academy of Periodontology case definitions. Serum 25(OH)D levels were classified as reflecting severe deficiency, deficiency, insufficiency, or sufficiency. Multivariate linear regression analysis was performed to assess the associations of serum 25(OH)D levels with periodontal parameters and the number of remaining teeth after adjusting for confounders including age, smoking status, alcohol consumption status, month of blood collection, and physical activity. Multivariate logistic regression was used to evaluate the association between serum vitamin D levels and severe periodontitis. An overall statistical analysis and a stratified analysis by sex were performed. Results: Overall, the rates of severe deficiency, deficiency, insufficiency, and sufficiency were 6.5%, 67.9%, 22.4%, and 3.2%, respectively. After adjustment for confounders, vitamin D levels were directly associated with the number of remaining teeth, an association that was significant in males, but not in females. Sufficient serum 25(OH)D was associated with a low frequency of severe periodontitis. Conclusions: This population-based cross-sectional study indicates that low serum 25(OH) D is significantly associated with tooth loss and severe periodontitis in Koreans aged 50 years and older.

• Animal Bioscience
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• v.34 no.10
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• pp.1579-1589
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• 2021

Objective: This study was conducted to generate single stranded DNA oligonucleotides with selective affinity to bovine spermatozoa, assess its binding potential and explore its potential utility in trapping spermatozoa from suspensions. Methods: A combinatorial library of 94 mer long oligonucleotide was used for systematic evolution of ligands by exponential enrichment (SELEX) with bovine spermatozoa. The amplicons from sixth and seventh rounds of SELEX were sequenced, and the reads were clustered employing cluster database at high identity with tolerance (CD-HIT) and FASTAptamer. The enriched nucleotides were predicted for secondary structures by Mfold, motifs by Multiple Em for Motif Elicitation and 5' labelled with biotin/6-FAM to determine the binding potential and binding pattern. Results: We generated 14.1 and 17.7 million reads from sixth and seventh rounds of SELEX respectively to bovine spermatozoa. The CD-HIT clustered 78,098 and 21,196 reads in the top ten clusters and FASTAptamer identified 2,195 and 4,405 unique sequences in the top three clusters from the sixth and seventh rounds, respectively. The identified oligonucleotides formed secondary structures with delta G values between -1.17 to -26.18 kcal/mol indicating varied stability. Confocal imaging with the oligonucleotides from the seventh round revealed different patterns of binding to bovine spermatozoa (fluorescence of the whole head, spot of fluorescence in head and mid- piece and tail). Use of a 5'-biotin tagged oligonucleotide from the sixth round at 100 pmol with 4×10⁶ spermatozoa could trap almost 80% from the suspension. Conclusion: The binding patterns and ability of the identified oligonucleotides confirms successful optimization of the SELEX process and generation of aptamers to bovine spermatozoa. These oligonucleotides provide a quick approach for selective capture of spermatozoa from complex samples. Future SELEX rounds with X- or Y- enriched sperm suspension will be used to generate oligonucleotides that bind to spermatozoa of a specific sex type.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.5
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• pp.492-501
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• 2021

This study was undertaken to identify the perception and sexual attitude of nursing students and obstetrics and pediatric nurses towards unwed mothers, and to identify differences in the general characteristics. Data were collected as a self-reported questionnaire survey from September, 2018 to January, 2019. Subjects included 94 nursing students enrolled at 2 nursing colleges, and 101 nurses of 8 hospitals located in the B & C Metropolitan. The data collected was analyzed by descriptive statistics, frequencies, percentages, means and standard deviations, independent t-test, and one-way ANOVA. Comparing results obtained from nursing students and nurses revealed a statistically significant difference in their overall perception of an unwed mother and sexual attitude. The perception of an unwed mother showed significant differences considering the grade, age and sibling status of nursing students, whereas nurses revealed significantly different perceptions according to their age, occupational position, clinical career, career of current work department, marital status, and children status. Sexual attitude was significantly different for nursing students according to their experience contact with unwed mother, whereas perception of nurses differed significantly for sexual attitude according to experience contact with unwed mother, types of hospital, and marital status. We propose that data obtained from this research can be used as basic data for research and education related to the perception of unwed mothers and sexual attitude of nursing students and nurses.

• Journal of Korea Entertainment Industry Association
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• v.14 no.5
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• pp.277-287
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• 2020

The purpose of this study was to investigate the standardization of daily average smartphone use time among adolescents. The data were analyzed using the data from Korea youth risk behavior web-based survey of 2017, and the total number of students analyzed was 54,603. Frequency analysis, independent t test, Pearson correlation analysis, and one-way ANOVA were used for statistical analysis. As a result, the correlation coefficient between smartphone use time, age, and grade was very low (r =.025~.039). There was no significant difference in the usage of smartphone between middle and high school students(p>.05). Time of smartphone use was significantly higher in middle school students as the grade increased(p<.05). In high school students, second-year students had significantly more smartphone usage than first and third grade students(p<.05). The researchers described 54603 adolescents' average(minute) daily smartphone usage about sex(male, female), period of use(weekday, weekend), school(middle school, high school), and grade(first, second, third) as a 7th quartile. We suggest that the standard value of smartphone use time can be used as a basis for the physical and mental health management in adolescents. It is necessary to present a standard value that can prove the future overuse of smartphone.

• Journal of Korea Entertainment Industry Association
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• v.14 no.5
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• pp.193-205
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• 2020

The purpose of this study was to look into how social support for high school students was affecting suicidal ideation and verify how the moderating effect worked on risk factors in the relationship between social support and suicidal ideation. Specifically, three sub-factors of social support were classified into friend support, teacher support, and parent support, and were set as independent variables. In addition, suicidal ideation was dependent variables, gender, grade level, and school type as moderating variables. The main research results are as follows. First, teacher support, friend support, and parent support all appeared to have a significant negative effect on suicidal ideation. Second, the suicidal thoughts were higher in female students than in male students than in male students and in students of general high school than in those of vocational high school. Third, support from friends and parents was more effects in reducing suicidal thoughts for female students than male students. Fourth, the effect that teacher support that support and parent support reduce suicidal thoughts was greater for first graders than second graders. Bases on the results of the analysis, interviews were also conducted with high school teachers. Through the results of this study, I would like to propose practical measures to alleviate social problems related to suicide in high school students and to provide basic data for policy measures.

• Journal of Chest Surgery
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• v.55 no.1
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• pp.49-54
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• 2022

Background: We compared the safety and effectiveness of robotic anatomical resection and video-assisted thoracoscopic surgery (VATS). Methods: A retrospective analysis was conducted of the records of 4,283 patients, in whom an attempt was made to perform minimally invasive anatomical resection for lung cancer at Seoul National University Hospital from January 2011 to July 2020. Of these patients, 138 underwent robotic surgery and 4,145 underwent VATS. Perioperative outcomes were compared after propensity score matching including age, sex, height, weight, pulmonary function, smoking status, performance status, comorbidities, type of resection, combined bronchoplasty/angioplasty, tumor size, clinical T/N category, histology, and neoadjuvant treatment. Results: In total, 137 well-balanced pairs were obtained. There were no cases of 30-day mortality in the entire cohort. Conversion to thoracotomy was required more frequently in the VATS group (VATS 6.6% vs. robotic 0.7%, p=0.008). The complete resection rate (VATS 97.8% vs. robotic 98.5%, p=1.000) and postoperative complication rate (VATS 17.5% vs. robotic 19.0%, p=0.874) were not significantly different between the 2 groups. The robotic group showed a slightly shorter hospital stay (VATS 5.8±3.9 days vs. robotic 5.0±3.6 days, p=0.052). N2 nodal upstaging (cN0/pN2) was more common in the robotic group than the VATS group, but without statistical significance (VATS 4% vs. robotic 12%, p=0.077). Conclusion: Robotic anatomical resection in lung cancer showed comparable early outcomes when compared to VATS. In particular, robotic resection presented a lower conversion-to-thoracotomy rate. Furthermore, a robotic approach might improve lymph node harvesting in the N2 station.

• Journal of Korean Home Economics Education Association
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• v.34 no.1
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• pp.113-129
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• 2022

This study evaluated the dietary habits and dietary quality of the Korean elderly according to muscle strength status. This study was conducted on the elderly aged over 65 years who participated in the 2014-2018 Korea National Health and Nutrition Examination Survey. Subjects were classified into the normal muscle strength group(n=2,000) and the low muscle strength group(n=1,273) according to the handgrip strength. There was a significant difference in general characteristics, diet habits, and health behavior according to the muscle strength status. The normal muscle strength group had a higher total score of KHEI and a subtotal score of 「adequacy」 items. But there was not significant difference in the 「moderation」 items. For the 「balance of energy intake」 items, the normal muscle strength group had a higher subtotal score than the low muscle strength group only in among women. The prevalence of low muscle strength decreased in the highest quartile of the adjusted KHEI total score(p for trend=0.08). As a result of this study, it was found that KHEI was significantly associated with muscle strength. This study result can be used to provide dietary guidelines for the improvement of muscle strength in the elderly based on each item of KHEI and sex.

• Korean Journal of Poultry Science
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• v.49 no.4
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• pp.229-237
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• 2022

This study investigated the growth characteristics of four strains of newly developed synthetic Korean native commercial chickens (KNCs). We investigated a suitable growth curve model in KNCs and estimated the number of days to reach a 2 kg market weight. Body weight was measured at 2-week intervals from birth to 12 weeks of age. The growth curves were estimated using von Berteralanffy, Gompertz, and logistic functions. The results showed that males were significantly heavier than females at all ages, but there were no significant differences in body weight between strains, except at birth and 2 and 6 weeks of age. The coefficients of determination and adjusted determination of growth function had high goodness-of-fit (97.4~99.7). Of the growth curve parameters, the mature weight and growth ratio were higher in males than in females, but the maturity rate was similar in males and females. The inflection point occurred at approximately 7 weeks of age for females and 8 to 9 weeks of age for males. The weights estimated from the growth curve functions almost agreed with the actual weights, except for male weights estimated using the von Bertalanffy function. The coefficients of determination of the regression equations for weight to age were 0.9583 to 0.9746. The 8- and 10-week-old body weights estimated using the regression equation, and the 12-week-old weight estimated using the logistic function were most similar to the actual weight. Using these models, the estimated age of KNCs to reach 2 kg was 62.0~64.6 days for males and 74.9~78.6 days for females.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.3
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• pp.241-252
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• 2022

The purpose of this study was to evaluate the relationship between sella turcica morphology and delayed dental age. In total, 389 participants under 16 years old were selected. Dental age was evaluated by the Demirjian method and age discrepancy (AD), the value subtracted from dental age to chronological age, was calculated. The participants were divided into 8 groups based on the sella turcica type. Bridging ratio (BR) was defined as interclinoid distance divided by sella turcica length to determine the degree of sella turcica bridging (STB) and the participants were classified into 4 groups by BR. The data were statistically analyzed using the Kruskal Wallis test and the Mann Whitney test. Some groups with sella turcica abnormality showed lower AD than that of the normal group and the AD differences varied from 4 months to 1.3 year. As the STB severity increased, AD decreased. AD differences varied from 7 months to 1.19 year. No distinct differences were observed in sella turcica type and STB groups according to sex. The results indicate that sella turcica morphology is associated with delayed dental age. Sella turcica can be used as a supplementary indicator to predict dental development.

• Journal of the Korean Orthopaedic Association
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• v.55 no.6
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• pp.527-533
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• 2020

Purpose: This study compared the effects of a buprenorphine transdermal patch (BTDP) on the chest and knee for pain control after total knee arthroplasty (TKA). Materials and Methods: A retrospective case-control study was conducted from August 2018 to August 2019 on 231 patients who underwent TKA. Two hundred cases were selected considering age, sex, and body mass index. Before and after applying the BTDP, the Numeric Rating Scale (NRS), adverse effects and compliance were measured. All measurements in the chest application group (group A=100) and knee application group (group B=100) were compared. Results: NRS was similar in rest between the groups treated with BTDP, but at two days and three days afternoon, five, six, and seven days postoperatively in group B, the NRS was significantly lower than that of group A. The adverse effects of the central nervous system and gastrointestinal system after applying BTDP were significantly lower in group B than in group A. No significant differences in adverse effects of the cardiovascular system and skin were observed between the two groups. Regarding the maintenance of BTDP, group B was significantly higher than group A. Conclusion: The direct application of BTDP after TKA to painful knee joints showed excellent results in early postoperative pain control and can be a useful method for increasing patient compliance by reducing the frequency of adverse effects.