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Feasibility Study of Deep Inspiration Breath-Hold Based Volumetric Modulated Arc Therapy for Locally Advanced Left Sided Breast Cancer Patients

  • Swamy, Shanmugam Thirumalai;Radha, Chandrasekaran Anu;Kathirvel, Murugesan;Arun, Gandhi;Subramanian, Shanmuga
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.9033-9038
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    • 2014
  • Background: The purpose of this study was to assess the feasibility of deep inspiration breath-hold (DIBH) based volumetric modulated arc therapy (VMAT) for locally advanced left sided breast cancer patients undergoing radical mastectomy. DIBH immobilizes the tumor bed providing dosimetric benefits over free breathing (FB). Materials and Methods: Ten left sided post mastectomy patients were immobilized in a supine position with both the arms lifted above the head on a hemi-body vaclock. Two thermoplastic masks were prepared for each patient, one for normal free breathing and a second made with breath-hold to maintain reproducibility. DIBH CT scans were performed in the prospective mode of the Varian real time position management (RPM) system. The planning target volume (PTV) included the left chest wall and supraclavicular nodes and PTV prescription dose was 5000cGy in 25 fractions. DIBH-3DCRT planning was performed with the single iso-centre technique using a 6MV photon beam and the field-in-field technique. VMAT plans for FB and DIBH contained two partial arcs ($179^{\circ}-300^{\circ}CCW/CW$). Dose volume histograms of PTV and OAR's were analyzed for DIBH-VMAT, FB-VMAT and DIBH-3DCRT. In DIBH mode daily orthogonal ($0^{\circ}$ and $90^{\circ}$) KV images were taken to determine the setup variability and weekly twice CBCT to verify gating threshold level reproducibility. Results: DIBH-VMAT reduced the lung and heart dose compared to FB-VMAT, while maintaining similar PTV coverage. The mean heart $V_{30Gy}$ was $2.3%{\pm}2.7$, $5.1%{\pm}3.2$ and $3.3%{\pm}7.2$ and for left lung $V_{20Gy}$ was $18.57%{\pm}2.9$, $21.7%{\pm}3.9$ and $23.5%{\pm}5.1$ for DIBH-VMAT, FB-VMAT and DIBH-3DCRT respectively. Conclusions: DIBH-VMAT significantly reduced the heart and lung dose for left side chest wall patients compared to FB-VMAT. PTV conformity index, homogeneity index, ipsilateral lung dose and heart dose were better for DIBH-VMAT compared to DIBH-3DCRT. However, contralateral lung and breast volumes exposed to low doses were increased with DIBH-VMAT.

On Information Theoretical Research of the Korean Language (한국어의 정보이론적 연구 방향)

  • Lee, Jae-Hong;Yi, Chae-Hag
    • Annual Conference on Human and Language Technology
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    • 1992.10a
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    • pp.367-375
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    • 1992
  • 한국어는 다른 언어와는 달리 초성, 중성, 종성의 자소가 모여서 한 음절을 이룬다. 음절을 이루는 자소는 그 발생의 확률적 성질에 따라 확률변수로 간주된다. 음절 안에서 자소간의 발생의 상관관계는 자소간 조건부 확률 및 엔트로피로 표시된다. 음절이 모여서 단어를 이루고 단어를 이루는 음절은 그 발생의 확률적 성질에 따라 확률변수로 간주된다. 한국어 단어안에서 음절간의 발생의 상관관계는 음절간 조건부 확률 및 엔트로피로 표시된다. 수 있다. 그런데 가능한 음절의 종류가 매우 많기 때문에 음절 발생의 상관관계를 표시하는 지표로서 음절간 조건부 확률 대신 초성, 중성, 종성 단위의 조건부 확률을 사용하는 것이 음절간의 발생의 상관관계를 표시하는데 효과적이다. 이러한 한국어의 정보이론적 연구를 위하여서는 기초자료로서 한국어 단어의 빈도분포가 필요하다. 한국어 단어의 빈도분포의 포괄적인 조사는 1956년의 "우리말 말수 사용의 잦기 조사"가 유일한 실정이다. 시간 경과에 따른 한국어의 정보이론적 특성 변화의 분석을 위하여서는 한국어 단어 빈도의 주기적인 조사가 필요하다. 한국어에서 초성, 중성, 종성단위의 정보이론적 연구결과는 한국어 음성인식 및 함성, 자연언어처리, 암호법, 언어학, 음성학, 한국어부호 표준화 연구등에 이용될 것으로 기대된다. 남북한의 언어는 분단이 지속됨에 따라 상호 이질화가 진행되고 있다. 이러한 이질화를 극복하려는 부분적인 노력으로 남북한 언어의 한국어 영문표기의 단일화 등이 있었다. 이러한 노력에 병행하여 남한과 북한의 언어에 대한 정보이론적 비교 연구도 있어야 할 것이다. 정보를 효과적으로 캐싱할 수 있도록 인접한 데이터를 클러스터링해서 브로드캐스팅하여 이동 호스트의 구성 시간(setup time)을 최소화하였다. 그리고, 맨하탄거리(Manhattan Distance)를 사용해서 위치 의존 질의에서 사용하는 데이타를 캐싱하고 질의를 처리하는 방법을 제안한다. 맨하탄 거리를 이용해서 캐싱하면 도로에 인접해서 위치한 데이타를 효과적으로 캐싱할 수 있다. 또한, 거리 계산 방법으로 맨하탄 거리를 사용하면 도심에서 실제 이동 거리와 비슷한 값을 알 수 있고, 직선 거리 계산식에 비해서 계산식도 간단하기 때문에 시스템 계산량도 줄일 수 있다. 기준으로 라이신 부산물은 어분 단백질을 40%까지 대체가 가능하였으며, 아울러 높은 라이신 부산물의 대체 수준에 있어서 사료효율과 단백질 전환효율을 고려한다면 아미노산 첨가(라이신과 아르지닌)와 중화 효과에 좋은 결과가 있을 것으로 사료된다.의한 적정 양성수용밀도는 각고 5~6cm 크기의 경우 10~15개체가 적합하였다. 수증별 성장은 15~20 m 수층에서 빨랐으며, 성장촉진과 폐사를 줄이기 위해서는 고수온이 지속되는 7~10월에는 20~30m수층으로 채롱을 내려 양성하고 그 외 시기에는 15 m층 내외가 좋은 것으로 나타났다. 상품으로 출하 가능한 크기 인 각고 10 cm이상, 전중량 140 g 내외로 성장시 키기까지는 채묘후 22개월이 소요되었고, 출하시기는 전중량 증가가 최대에 이르는 3월에서 4월 중순이 경제적일 것으로 판단된다.er 90 % of good relative dynamic modulus of elasticity due

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Proposal for Technical Review of Adult Arcade Game (성인용 아케이드게임 기술심의 제안)

  • Song, Seung-keun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.10a
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    • pp.553-555
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    • 2013
  • Game Rating Board(GRB) of Korea set up in 29 October, 2006 has been 7th years and it will disappear in 23 November, 2013. For the first time the 'GRB' of Korea has the goal which held the nonofficial transfer of rating classification for game. But it had the justification which become more distant from the nonofficial transfer due to the affairs of 'See Story' in August, 2006. As a result, because of rapid normalization of game rating rather than the systematic transfer from 'Video Rating Board' of Korea cause no preparation of scientific professional rating review. It showed the entry-level appearance though stressing profession from the beginning of setup. Specially more transaction expense were increased because of no consistency and predictability for game review. However, it could be overcome by preparation for definite global standard and scientific rating system. Consequently technological possibility of BMM Korea based on 'Gaming Laboratory Institute(GLI)' standard expected to be alternative in the technical review of the adult arcade game.

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Cache Table Management for Effective Label Switching (효율적인 레이블 스위칭을 위한 캐쉬 테이블 관리)

  • Kim, Nam-Gi;Yoon, Hyun-Soo
    • Journal of KIISE:Information Networking
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    • v.28 no.2
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    • pp.251-261
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    • 2001
  • The traffic on the Internet has been growing exponentially for some time. This growth is beginning to stress the current-day routers. However, switching technology offers much higher performance. So the label switching network which combines IP routing with switching technology, is emerged. EspeciaJJy in the data driven label switching, flow classification and cache table management are needed. Flow classification is to classify packets into switching and non-switching packets, and cache table management is to maintain the cache table which contains information for flow classification and label switching. However, the cache table management affects the performance of label switching network considerably as well as flowclassification because the bigger cache table makes more packet switched and maintains setup cost lower, but cache is restricted by local router resources. For that reason, there is need to study the cache replacement scheme for the efficient cache table management with the Internet traffic characterized by user. So in this paper, we propose several cache replacement schemes for label switching network. First, without the limitation at switching capacity in the router. we introduce FIFO(First In First Out). LFC(Least Flow Count), LRU(Least Recently Used! scheme and propose priority LRU, weighted priority LRU scheme. Second, with the limitation at switching capacity in the router, we introduce LFC-LFC, LFC-LRU, LRU-LFC, LRU-LRU scheme and propose LRU-weighted LRU scheme. Without limitation, weighted priority LRU scheme and with limitation, LRU-weighted LRU scheme showed best performance in this paper.

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Analysis and Development of Experimental Method of Charle's Law Applicable to School (학교 현장에 적용 가능한 '샤를의 법칙' 실험방법의 분석 및 개발)

  • Min, Jung-Sook;Kim, Sung-Hee;Jeong, Dae-Hong
    • Journal of the Korean Chemical Society
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    • v.53 no.2
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    • pp.175-188
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    • 2009
  • In this study, we developed an experimental method of the Charles' law applicable to school. Science textbooks and literatures on this principle were analyzed to extract factors utilized in organizing the experimental setup and method. A combined structure such as with a vial and a glass tube, the former of which is for deciding the total volume and the latter of which is for easy measurement of volume, was better in measurement of volume with temperature rather than a simple structure such as syringe. Use of graduated cylinder as a water bath to control the temperature showed advantage in cooling time than using other bath of larger volume such as a beaker. A liquid drop was used as a plug in the glass tube. This plug has little resistance with the glass wall when the gas volume changes. Water as a liquid drop in the glass tube had a significant effect in volume change of gas due to evaporation, especially in the beginning of the measurement. Glycerol showing negligible effect in volume change was used. This method took about one hour and produced a good linear relationship between the temperature and volume of gas with $R^2$ = 0.999 and absolute zero temperature = $-216.7\;{^{\circ}C}$. The Charles' law experiment developed in this study can be performed with appropriate adjustment of procedure considering the purpose of the curriculum of science and chemistry subject at each school level.

A System for Concurrent TMS-fMRI and Evaluation of Imaging Effects (동시 뇌경두개자기자극-기능자기공명영상 시행을 위한 홀더 제작과 시뮬레이션 및 영상 데이터 평가)

  • Kim, Jae-Chang;Kyeong, Sunghyon;Lee, Jong Doo;Park, Hae-Jeong
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.3
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    • pp.169-180
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    • 2013
  • Purpose : The purpose of this study was to setup a concuurent transcranial magnetic stimulation (TMS)-functional MRI (fMRI) system for understanding causality of the functional brain network. Materials and Methods: We manufactured a TMS coil holder using nonmagnetic polyether ether ketone (PEEK). We simulated magnetic field distributions in the MR scanner according to TMS coil positions and angles. To minimize image distortions caused by TMS application, we controlled fMRI acquisition and TMS sequences to trigger TMS during inter-volume intervals. Results: Simulation showed that the magnetic field below the center of the coil was dramatically decreased with distance. Through the MR phantom study, we confirmed that TMS application around inter-volume acquisition time = 100 miliseconds reduced imaging distortion. Finally, the applicability of the concurrent TMS-fMRI was tested in preliminary studies with a healthy subject conducting a motor task within TMS-fMRI and passive motor movement induced by TMS in fMRI. Conclusion: In this study, we confirmed that the developed system allows use of TMS inside an fMRI system, which would contribute to the research of brain activation changes and causality in brain connectivity.

A Study of Field Application Process of Public Key Algorithm RSA Based on Mathematical Principles and Characteristics through a Diagnostic (수학원리와 특성 진단을 기반으로 한 공개키 RSA 알고리즘의 현장 적용 프로세스)

  • Noh, SiChoon;Song, EunJee;Moon, SongChul
    • Journal of Service Research and Studies
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    • v.5 no.2
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    • pp.71-81
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    • 2015
  • The RSA public key encryption algorithm, a few, key generation, factoring, the Euler function, key setup, a joint expression law, the application process are serial indexes. The foundation of such algorithms are mathematical principles. The first concept from mathematics principle is applied from how to obtain a minority. It is to obtain a product of two very large prime numbers, but readily tracking station the original two prime number, the product are used in a very hard principles. If a very large prime numbers p and q to obtain, then the product is the two $n=p{\times}q$ easy station, a method for tracking the number of p and q from n synthesis and it is substantially impossible. The RSA encryption algorithm, the number of digits in order to implement the inverse calculation is difficult mathematical one-way function and uses the integer factorization problem of a large amount. Factoring the concept of the calculation of the mod is difficult to use in addition to the problem in the reverse direction. But the interests of the encryption algorithm implementation usually are focused on introducing the film the first time you use encryption algorithm but we have to know how to go through some process applied to the field work This study presents a field force applied encryption process scheme based on public key algorithms attribute diagnosis.

Application of 3D printer in dental clinic (치과 진료실에서 3D 프린트의 활용)

  • Kim, Hyun Dong
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.27 no.2
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    • pp.82-96
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    • 2018
  • 3D printing is a process of producing 3d object from a digital file in STL format by joining, bonding, sintering or polymerizing small volume elements by layer. The various type of 3d printing is classified according to the additive manufacturing strategies. Among the types of 3D printer, SLA(StereoLithography Apparatus) and DLP(Digital Light Processing) 3D printer which use polymerization by light source are widely used in dental office. In the previous study, a full-arch scale 3d printed model is less precise than a conventional stone model. However, in scale of quadrant arch, a 3d printed model is significantly precise than a five-axis milled model. Using $3^{rd}$ Party dental CAD program, full denture, provisional crowns and diagnostic wax-up model are fabricated by 3d printer in dental office. In Orthodontics, based on virtual setup model, indirect bracket bonding tray can be generated by 3d printer. And thermoforming clear aligner can be fabricated on the 3d printed model. 3D printed individual drilling guide enable the clinician to place the dental implant on the proper position. The development of layer additive technology enhance the quality of 3d printing object and shorten the operating time of 3D printing. In the near future, traditional dental laboratory process such as casting, denture curing will be replaced by digital 3D printing.

Preliminary Experimental Study for Water Recovery and Particulate Matter Reduction through a Hybrid System that Combines Exhaust Cooling and Absorption from Ships (선박배출 배기냉각과 흡수식이 결합된 하이브리드 시스템을 통한 물 회수 및 미세먼지 저감을 위한 기초실험연구)

  • Youngmin Kim;Donggil Shin;Younghyun Ryu
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.7
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    • pp.1252-1258
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    • 2022
  • The exhaust gas from the marine engines include a quantity of water vapor and particulate matter. The total particulate matter includes filterable particulate matter (FPM) and condensable particulate matter (CPM) that condense after releasing into the atmosphere. The portion of CPM is higher than that of FPM that is removable through the filter before discharging. An experimental setup for waste heat and water recovery and removal of CPM in the exhaust gas was tested using an industrial gas boiler in the laboratory. The water and CPM in the exhaust gas were removed through the first stage of cooling method and further removed through the second stage of absorption method. The efficiencies of water recovery were 73% after the first stage of cooling method and 90% after the second stage of absorption method. At the same time, the CPM was removed by 80-90% through the processes. The waste heat recovered could be used to process heat, and the water recovered could be used to process water in the ship. Furthermore, the CPM, which is a major source of the particulate matter but not subject to administrative regulation, could be removed effectively.

A of Radiation Field with a Developed EPID

  • Y.H. Ji;Lee, D.H.;Lee, D.H.;Y.K. Oh;Kim, Y.J.;C.K. Cho;Kim, M.S.;H.J. Yoo;K.M. Yang
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.67-67
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    • 2003
  • It is crucial to minimize setup errors of a cancer treatment machine using a high energy and to perform precise radiation therapy. Usually, port film has been used for verifying errors. The Korea Cancer Center Hospital (KCCH) has manufactured digital electronic portal imaging device (EPID) system to verify treatment machine errors as a Quality Assurance (Q.A) tool. This EPID was consisted of a metal/fluorescent screen, 45$^{\circ}$ mirror, a camera and an image grabber and could display the portal image with near real time KIRAMS has also made the acrylic phantom that has lead line of 1mm width for ligh/radiation field congruence verification and reference points phantom for using as an isocenter on portal image. We acquired portal images of 10$\times$10cm field size with this phantom by EPID and portal film rotating treatment head by 0.3$^{\circ}$, 0.6$^{\circ}$ and 0.9$^{\circ}$. To check field size, we acquired portal images with 18$\times$18cm, 19$\times$19cm and 20$\times$20cm field size with collimator angle 0$^{\circ}$ and 0.5$^{\circ}$ individually. We have performed Flatness comparison by displaying the line intensity from EPID and film images. The 0.6$^{\circ}$ shift of collimator angle was easily observed by edge detection of irradiated field size on EPID image. To the extent of one pixel (0.76mm) difference could be detected. We also have measured field size by finding optimal threshold value, finding isocenter, finding field edge and gauging distance between isocenter and edge. This EPID system could be used as a Q.A tool for checking field size, light/radiation congruence and flatness with a developed video based EPID.

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