• Korean Journal of Veterinary Research
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• v.39 no.5
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• pp.1006-1012
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• 1999

This study was conducted to evaluate the ELISA kit for measuring the level of cortisol in the urine. The CV of within-run variation and day to day variation were 0.4~2.8 and 1.8~5.7, respectively. The minimum limitation of measurement was 1ng/ml. The cross reaction was high ($CR_{50}(%)=11.4{\sim}43.2$) in prednisolone, 11-deoxycortisol, 21-deoxycortisol and predinosone. There was low and no cross reaction in other steroid. To develop the ELISA kit we measured the cortisol level in diluted urine with PBS (procedure I), extracted urine with methylene chloride (procedure II) and extracted methylene chloride-extracted urine from thin-layer chromatography (procedure III). The CV value of procedure I, II, III was 9.4~28.3%, 7.2~8.9% and 2.5~5.7%, respectively. There was significant difference between procedure I with II, and pro-cedure I with III(p < 0.01), but no difference between procedure II with III significantly(p < 0.01). The mean UCCR of urine collected through am 8 to 10 was $9.5{\pm}7.6$(0.14~28.0) in 12-month-old dog(n = 47). In this study we can measure the cortisol level in extracted urine with methylene chloride and sequential thin-layer chromatography accurately using ELISA kit.

• Journal of the Korea Society of Computer and Information
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• v.4 no.1
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• pp.28-37
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• 1999

In this paper. we developed a delay test architecture and test procedure for clocked 5-bit asynchronous counter circuit based on boundary scan architecture. To develope, we analyze the problems of conventional method on delay test for clocked sequential circuit in boundary scan architecture. This paper discusses several problems of delay test on boundary scan architecture for clocked sequential circuit. Conventional test method has some problems of improper capture timing, of same pattern insertion, of increase of test time. We suggest a delay test architecture and test procedure, is based on a clock count-generation technique to generate continuous clocks for clocked input of CUT. The simulation results or 5-bit counter shows the accurate operation and effectiveness of the proposed delay test architecture and procedure.

• Structural Engineering and Mechanics
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• v.26 no.5
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• pp.499-516
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• 2007

An experimental method denoted as Impulse Method is proposed as a cost-effective non-destructive technique for the on-site evaluation of concrete elastic modulus in existing structures: on the basis of Hertz's quasi-static theory of elastic impact and with the aid of a simple portable testing equipment, it makes it possible to collect series of local measurements of the elastic modulus in an easy way and in a very short time. A Hypothesis Testing procedure is developed in order to provide a statistical tool for processing the data collected by means of the Impulse Method and assessing the possible occurrence of significant variations in the elastic modulus without exceeding some prescribed error probabilities. It is based on a particular formulation of the renowned sequential probability ratio test and reveals to be optimal with respect to the error probabilities and the required number of observations, thus further improving the time-effectiveness of the Impulse Method. The results of an experimental investigation on different types of plain concrete prove the validity of the Impulse Method in estimating the unknown value of the elastic modulus and attest the effectiveness of the proposed Hypothesis Testing procedure in identifying significant variations in the elastic modulus.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.3
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• pp.258-266
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• 2008

The conventional approximate optimization method, which uses the statistical design of experiments(DOE) and response surface method(RSM), can derive an approximated optimum results through the iterative process by a trial and error. The quality of results depends seriously on the factors and levels assigned by a designer. The purpose of this study is to propose a new technique, which is called a sequential design of experiments(SDOE), to reduce a trial and error procedure and to find an appropriate condition for using artificial neural network(ANN) systematically. An appropriate condition is determined from the iterative process based on the analysis of means. With this new technique and ANN, it is possible to find an optimum design accurately and efficiently. The suggested algorithm has been applied to various mathematical examples and a structural problem.

• Korean Management Science Review
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• v.23 no.3
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• pp.13-25
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• 2006

To reduce the signaling tost of paging in mobile communication, sequential paging schemes are proposed by partitioning a location area into several paging areas such that each area is paged sequentially. Necessary conditions for the optimal partition of cells with delay bound are examined by considering the mobiles location probability at each cell. The Optimal Cell Partitioning (OCP) is proposed based on the necessary conditions and the fathoming rule which trims off the unnecessary solution space and expedite the search process. Two Heuristics, BSG and BNC are also presented to further increase the computational efficiency in real-world paging scheme for the next generation mobile systems. The effectiveness of the 1)reposed paging schemes is illustrated with computational results. The Heuristic BSG that performs the search in the most promising solution group outperforms the best existing procedure with the 6-69% gain in paging cost in problems with 100 cells.

• Communications for Statistical Applications and Methods
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• v.23 no.4
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• pp.287-296
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• 2016

Subjects on one side of the covariate population can be allocated to the inferior treatment when there is interaction between the covariate and treatment along with a response-adaptive (RA) design without covariate adjustment. An RA design allows a newly entered subject to have a better chance so that the subject is treated by a superior treatment based on cumulative information from previous subjects. A covariate-adjusted response-adaptive (CARA) is the same as RA design and additionally adjusts the allocation based on individual covariate information. A comparison has been made for the sequential estimation procedure with and without covariate adjustment to see how ignoring significantly interactive covariate affects the correct treatment allocation. Using logistic models, we present simulation results regarding the coverage probability of treatment effect, correct allocation, and stopping time.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.6
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• pp.1041-1049
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• 2003

In this paper, a new local two-point approximation method which is based on the exponential intervening variable is proposed. This new algorithm, called the Two-Point Convex Approximation(TPCA), use the function and design sensitivity information from the current and previous design points of the sequential approximate optimization to generate a sequence of convex, separable subproblems. This paper describes the derivation of the parameters associated with the approximation and the numerical solution procedure. In order to show the numerical performance of the proposed method, a sequential approximate optimizer is developed and applied to solve several typical design problems. These optimization results are compared with those of other optimizers. Numerical results obtained from the test examples demonstrate the effectiveness of the proposed method.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.58 no.12
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• pp.2484-2491
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• 2009

This paper proposes robust state feedback control of asynchronous sequential machines with model uncertainty. The considered asynchronous machine is deterministic, but its state transition function is partially known before executing a control process. The main objective is to derive the existence condition for a corrective controller for which the behavior of the closed-loop system can match a prescribed model in spite of uncertain transitions. The proposed control scheme also has learning ability. The controller perceives true state transitions as it undergoes corrective actions and reflects the learned knowledge in the next step. An adaptation is made such that the controller can have the minimum number of state transitions to realize a model matching procedure. To demonstrate control construction and execution, a VHDL and FPGA implementation of the proposed control scheme is presented.

• The Korean Journal of Applied Statistics
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• v.3 no.1
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• pp.105-120
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• 1990

In this paper, a sequential test procedure is defined by using cumulative sum (CUSUM) of statistics. The properties as well as the efficiency of the CUSUM test are studied in comparison with the sequential probability ratio test (SPRT). It was shown that, the operating characteristic function and the average sample numbrer can be derived by Wald and Wiener process approximations. Also it was shown that the statistics used in the CUSUM test is determined to provide asymtotically equivalent efficiency compared to the SPRT. The efficiency of the CUSUM test and the SPRT are cpmpared by an example for some limited number of cases in the exponential distribution.

• Journal of the Korean Statistical Society
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• v.24 no.2
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• pp.337-347
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• 1995

In the problem of some sequential estimation, the stopping times may be written in the form $N(c) = inf{n \geq n_0; n \geq c^2 S^2_n/\delta^2 (\bar{X}_n)}$ where ${s^2_n}$ and ${\bar{X}_n}$ are the sequences of sample variance and sample mean of the independently and identically distributed (i.i.d.) random variables with distribution $F_{\theta}(x), \theta \in \Theta$, respectively, and $\delta$ is either constant or any given positive real valued function. We obtain some asymptotic normality and asymptotic expectation of the N(c) in various limiting situations. Specially, uniform asymptotic normality and uniform asymptotic expectation of the N(c) are given.