• Journal of Photoscience
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• v.6 no.3
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• pp.129-133
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• 1999

Microperoxidase 8 (MP8) has been prepared by sequential hydrolysis of cytochrome C by pepsin and trypsin. This five-coordinated heme-octapetide fragment provides a uniques structure to evaluate the electronic coupling efficiency to the iron through axial position and porphyrin edge. At alkali pH, Ru(bpy)2(im)22+ is completely quenched in AcMP8Ru complex . Transient kinetics measurement showed the decay rate to be ~1 $\times$1012S-1. Ruthenium bipyridine complex with a carboxyl group substituted bipyridine has been prepared adn reacted with MR 8 to yield N-terminus bound RuMP8 complex. The luminescence decay rate has been measured as 1 $\times$109S-1. By using semiclassical electron transfer theory, we found the electron transfer efficiency through axial positioin of iron prophyrin is as good through prophyrin edge.

• Journal of the Korean Geotechnical Society
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• v.15 no.3
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• pp.161-176
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• 1999

A powerful numerical method that can be used for modeling rock-structure interaction is the Discontinuous Deformation Analysis (D D A) method developed by Shi in 1988. In this method, rock masses are treated as systems of finite and deformable blocks. Large rock mass deformations and block movements are allowed. Although various extensions of the D D A method have been proposed in the literature, the method is not capable of modeling water-block interaction, sequential loading or unloading and rock reinforcement; three features that are needed when modeling surface or underground excavation in fractured rock. This paper presents three new extensions to the D D A method. The extensions consist of hydro-mechanical coupling between rock blocks and steady water flow in fractures, sequential loading or unloading, and rock reinforcement by rockbolts, shotcrete or concrete lining. Examples of application of the D D A method with the new extensions are presented. Simulations of the underground excavation of the \ulcornerUnju Tunnel\ulcorner in Korea were carried out to evaluate the influence of fracture flow, excavation sequence and reinforcement on the tunnel stability. The results of the present study indicate that fracture flow and improper selection of excavation sequence could have a destabilizing effect on the tunnel stability. On the other hand, reinforcement by rockbolts and shotcrete can stabilize the tunnel. It is found that, in general, the D D A program with the three new extensions can now be used as a practical tool in the design of underground structures. In particular, phases of construction (excavation, reinforcement) can now be simulated more realistically.

• Korean Journal of Optics and Photonics
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• v.23 no.1
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• pp.23-31
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• 2012

In this paper, we developed a frequency-domain diffuse optical imaging (DOI) system for imaging non-invasively using near-infrared (NIR) light sources and detectors. 70-MHz modulation and a homodyne scheme were adopted. By calibration of the coupling coefficients, concurrent detection measurements by 4 detector sets were optimized. We presented experimental reconstruction images of absorption and scattering coefficients in a liquid phantom, located an anomaly in the phantom and determined its optical properties. The images by the multi-channel concurrent detection were improved over the results by single-channel sequential detection. Tomographic slices of absorption and scattering coefficients in the phantom with an anomaly were also presented.

• Macromolecular Research
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• v.14 no.3
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• pp.272-286
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• 2006

Dendritic hyperbranched poly(methyl methacrylate)s (PMMA)s, whose branched architectures resemble the 'dendron' part(s) of dendrimer, were synthesized by an iterative methodology consisting of two reactions in each iteration process: (a) a coupling reaction of u-functionalized, living, anionic PMMA having two tert-butyldimethylsilyloxymethylphenyl(SMP) groups with benzyl bromide(BnBr)-chain-end-functionalized PMMA, and (b) a transformation reaction of the introduced SMP groups into BnBr functionalities. These two reactions, (a) and (b), were repeated three times to afford a series of dendron-like, hyperbranched (PMMA)s up to third generation. Three dendron-like, hyperbranched (PMMA)s different in branched architecture were also synthesized by the same iterative methodology using a low molecular weight, functionalized 1,1-diphenylalkyl anion prepared from sec-BuLi and 1,1-bis(3-tert-butyldime-thylsilyloxymethylphenyl)ethylene in the reaction step (b) in each iterative process. Furthermore, structurally similar, dendron-like, hyperbranched block copolymers could be successfully synthesized by the iterative methodology using $\alpha$-functionalized, living, anionic poly(2-(perfluorobutyl) ethyl methacrylate) (PRfMA) in addition to $\alpha$-functionalized, living PMMA. Accordingly, the resulting block copolymers were comprised of both PMMA and PRfMA segments with different sequential orders. After the block copolymers were cast into films and annealed, their surface structures were characterized by angle-dependent XPS and contact angle measurements. All three samples showed significant segregation and enrichment of PRfMA segments at the surfaces.

• Tunnel and Underground Space
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• v.34 no.2
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• pp.127-142
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• 2024

The robustness of a numerical method means that its computational performance is maintained under various modeling conditions. New numerical methods or codes need to be assessed for robustness through benchmark testing. The TOUGH-FLAC modeling approach has been applied to various fields such as subsurface carbon dioxide storage, geological disposal of spent nuclear fuel, and geothermal development both domestically and internationally, and the modeling validity has been examined by comparing the results with experimental measurements and other numerical codes. In the present study, a benchmark test of the TOUGH-FLAC approach was performed based on a coupled thermal-hydro-mechanical behavior problem with an analytical solution. The analytical solution is related to the temperature, pore water pressure, and mechanical behavior of a fully saturated porous medium that is subjected to a point heat source. The robustness of the TOUGH-FLAC approach was evaluated by comparing the analytical solution with the results of numerical simulation. Additionally, the effects of thermal-hydro-mechanical coupling terms, fluid phase change, and timestep on the computation of coupled behavior were investigated.

• Journal of Photoscience
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• v.7 no.4
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• pp.143-148
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• 2000

Studies have been conducted to explore single electron transfer(SET) promoted photocyclization of ($\omega$-phthalimidoalkoxy)acetic acids(alkoxy=ethoxy, n-propoxy and n-butyloxy). Photocyclizations occur in methanol or acetone in high yields to produce cyclized products in which phthalimide carbonyl carbon is bonded to the carbon of side chain in place of the carboxylic group. These photocyclizations are thought to proceed through pathways involving intramolecular SET from oxygen in the $\alpha$-carboxymethoxy groups to the singlet excited state phthalimide moieties followed by decarboxylation of the intermediate $\alpha$-carboxymethoxy cation fadicals and cyclizations by radical coupling. The photocyclizations occur ca. three times faster in both methanol or acetone with one equivalent of sodium hydroxide added to the reactions and occur slower in acetone than in methanol. The efficient and regiselective cyclization reactions observed for photolyses in methanol represent synthetically useful processes for construction of heterocyclic compounds.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.440-444
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• 2003

A new approach for ground water treatment combines a permeable Fe(0) barrier to breakdown higher chlorinated solvents like PCE and TCE with a down gradient aerobic biological treatment system to biotransform less chlorinated solvents, such as DCE and vinyl chloride (VC). The expected bacterial performance down gradient of an Fe(0) barrier was evaluated through laboratory batch experiments with a toluene-degrading mixed culture that cometabolically transforms cis-1,2-DCE and VC. The amount of cis-1,2-DCE (initially at 2,000 ppb) and VC (initially at 2,000 ppb) transformed was controlled by the initial toluene(20,000 ppb) concentration. VC was removed much more effectively than Cis-1,2-DCE, and a higher toluene concentration in comparison to the co-substrate concentrations was needed for complete co-substrate removal. Overall, the coupling of an Fe(0) barrier and subsequent biodegradation appears feasible for remediation of complex mixtures of chlorinated solvents and petroleum hydrocarbons in groundwater.

• Structural Engineering and Mechanics
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• v.76 no.2
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• pp.163-173
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• 2020

As a vehicle moves on multiple equal-span beams at constant speed, the running vehicle would be subjected to repetitive excitations from the beam vibrations under it. Once the exciting frequency caused by the vibrating beams coincides with any of the vehicle's frequencies, resonance would take place on the vehicle. A similar resonance phenomenon occurs on a beam subject to sequential moving loads with identical axle-intervals. To reduce both resonant phenomena of a vehicle moving on guideway girders, this study proposed an additional feedback controller based the condensed virtual dynamic absorber (C-VDA) scheme. This condensation scheme has the following advantages: (1) the feedback tuning gains required to adapt the control currents or voltages are directly obtained from the tuning forces of the VDA; (2) the condensed VDA scheme does not need additional DoFs of the absorber to control the vibration of the maglev-vehicle/guideway system. By decomposing the maglev vehicle-guideway coupling system into two sub-systems (the moving vehicle and the supporting girders), an incremental-iterative procedure associated with the Newmark method is presented to solve the two sets of sub-system equations. From the present studies, the proposed C-VDA scheme is a feasible approach to suppress the interaction response for a maglev vehicle in resonance moving on a series of guideway girders.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.2 s.95
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• pp.161-168
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• 2005

The absorbing material is mostly used to changing the acoustic energy to the heat energy in the passive control, and that consists of the porous media. That controls an air borne noise while the stiffened plates, damping material and additional mass control a structure borne noise. The additional mass can decrease the sound by mass effect and shift of natural frequency, and damping material can decrease the sound by damping effect. The passive acoustic control using these kinds of control materials has an advantage that is possible to control the acoustic in the wide frequency band and the whole space at a price as compared with the active control using the various electronic circuit and actuator. But the space efficiency decreased and the control ability isn't up to the active control. So it is necessary to maximize the control ability in the specific frequency to raise the capacity of passive control minimizing the diminution of space efficiency such an active control. Therefore, the characteristics of control materials and the optimum layout of control materials that attached to the boundary of structure-acoustic coupled cavity were studied using sequential optimization on this study.

• Archives of Pharmacal Research
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• v.28 no.8
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• pp.983-987
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• 2005

Hydrogels composed of glycidyl methacrylate dextran (GMD) and poly(acrylic acid, PM) were prepared by UV irradiation method for colon-specific drug delivery. GMD was synthesized by coupling of glycidyl methacrylate to dextran in the presence of 4-(N,N-dimethylamino)pyridine. GMD was photo-polymerized by ammonium peroxydisulfate as initiating system in phosphate­buffered solution (0.1 M, pH 7.4). And then, acrylic acid monomer was added and subsequently heat-polymerized by 2,2'-azobisisobutyronitrile as an initiator. The hydrogels exhibited high swelling ratio (about 20) at $37^{\circ}C$, and showed a pH-dependent swelling behavior. In addition, the swelling ratio of the hydrogel was remarkably enhanced to about 45 times in the presence of dextranase at pH 7.4. The swelling-deswelling behavior proceeded reversibly for the GMD/PM hydrogels between pH 2 and pH 7.4. Release of 5-aminosalicylic acid from the GMD/PAA hydrogels was evaluated in simulated gastrointestinal pH fluids in the absence or presence of dextranase. We concluded that the hydrogels prepared could be used as a dual-sensitive drug carrier for sequential release in gastrointestinal tract.