• 대한두개안면성형외과학회지
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• 제23권6호
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• pp.256-261
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• 2022

Background: Treating panfacial fractures (PFFs) can be extremely difficult even for experienced surgeons. Although several authors have attempted to systemize the surgical approach, performing surgery by applying a unidirectional sequence is much more difficult in practice. The purpose of this study was to review the literature on PFF surgery sequence and to understand how different surgical specialists-plastic reconstructive surgery (PRS) and oral maxillofacial surgery (OMS)-chose sequence and review PFFs fixation sequence in clinical cases. Methods: The PubMed and Google Scholar databases were scoured for publications published up until May 2020. Data extracted from the studies using standard templates included fracture part, fixation sequence, originating specialist, and the countries. Bibliographic details like author and year of publication were also extracted. Also, we reviewed the data for PFFs patients in the Trauma Registry System of Dankook University Hospital from 2011 to 2021. Results: In total, 240 articles were identified. This study comprised 22 studies after screening and full-text analysis. Sixteen studies (12 OMS specialists and 4 PRS specialists) used a "bottom-top" approach, whereas three studies (1 OMS specialist and 2 PRS specialists) used a "top-bottom" method. However, three studies (only OMS specialists) reported on both sequences. In our hospital, there were a total of 124 patients with PFF who were treated during 2011 to 2021; 64 (51.6%) were in upper-middle parts, 52 (41.9%) were in mid-lower parts, and eight (6.5%) were in three parts. Conclusion: Bottom-top sequencing was mainly used in OMS specialists, and top-bottom sequencing was used at a similar rate by two specialists in literature review. In our experience, however, it was hard to consistently implement unidirectional sequence suggested by a literature review. We realigned the reliable and stable buttresses first with tailoring individually for each patient, rather than proceeding in the unidirectional sequence like bottom-top or top-bottom.

• 정보처리학회논문지D
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• 제11D권4호
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• pp.845-854
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• 2004

모티프 데이터베이스는 새롭게 등장하는 원시 단백질 서열의 기능 및 구조 예측에 사용된다. 이러한 모티프 데이터베이스들은 원시 단백질 서열의 빠른 성장과 더불어 급속한 이용 증가 추세를 보이고 있으며, 최근에 이르러 모티프 자원 통합에 관한 연구가 진행되고 있다. 그러나 이러한 모티프 데이터베이스들은 각기 개별적인 메소드로 개발되었기 때문에 각기 다른 형식의 검색 결과를 제공한다. 이러한 문제 해결을 위한 데이터베이스 통합에서는 데이터베이스 자동 갱신 문제, 복잡한 질의 처리 문제, 중복된 데이터베이스 엔트리 핸들링 문제, XML 지원 문제 등을 지니고 있다. 이 논문에서는 기존 문제점들을 해결하기 위하여 데이터베이스 자원 통합 방법론을 제안하였고, 통합된 데이터베이스의 주기적 갱신 방안과 XML로의 변환에 관하여 기술하였다. 아울러 구축된 통합 데이터베이스와 사례 데이터베이스를 비교 평가하였다.

• 전자공학회논문지B
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• 제32B권5호
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• pp.671-682
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• 1995

In this paper, we propose a multimedia query language MQL which defines and manipulates multimedia data as integration of monomedia data in time and space. The MQL is designed for a multimedia data model, called the object-relationship model, and based on the multimedia object calculus which formally describes operations on multimedia data. The SQL- like syntax for class definition and object manipulation, such as retrieval, insert, update, and delete, is defined. We show how the MQL can represent the user queries using composite temporal-spatial class structures and various relationships, such as equivalence and sequence.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2001년도 봄 학술발표논문집 Vol.28 No.1 (B)
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• pp.202-204
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• 2001

본 논문에서는 대형 시퀀스 데이터베이스에서 타임 워핑을 지원하는 유사 검색을 효과적으로 처리하는 방안에 관하여 논의한다. 타임 워핑은 시퀀스의 길이가 서로 다른 경우에도 유사한 패턴을 갖는 시퀀스들을 찾을 수 있도록 해 주는 변환이다. 타임 워핑 거리는 삼각형 부등식 성질을 만족하지 못하므로 기존의 기법들은 착오 기각 없이 다차원 인덱스를 사용할 수 없었다. 본 논문에서는 타임 워핑을 지원하는 새로운 인덱스 기반 유사 검색 기법을 제안한다. 제안된 주요 목표는 착오 기각 없이 대형 데이터베이스에서도 좋은 검색 성능을 보장하는 것이다. 다양한 실험을 통하여 제안된 기법의 우수성을 규명한다. 실험 결과에 의하면, 제안된 기법은 기존의 기법과 비교하여 약 4배에서 43배까지의 성능 개선 효과를 가지는 것을 나타났다.

• Journal of Microbiology and Biotechnology
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• 제17권3호
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• pp.408-413
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• 2007

Putrescine has a negative effect on health and is also used as an indicator of quality on meat products. We investigated the genes involved in putrescine production by Serratia liquefaciens IFI65 isolated from a spoiled Spanish dry-cured ham. We report here the genetic organization of its ornithine decarboxylase encoding region. The 5,506-bp DNA region showed the presence of three complete and two partial open reading frames. Putative functions have been assigned to several gene products by sequence comparison with proteins included in the databases. The second gene putatively coded for an ornithine decarboxylase. The functionality of this decarboxylase has been experimentally demonstrated by complementation to an E. coli defective mutant. Based on sequence comparisons of some enterobacterial ornithine decarboxylase regions, we have elaborated a hypothetical pathway for the acquisition of putrescine biosynthetic genes in some Enterobacteriaceae strains.

• 산업기술연구
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• 제21권A호
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• pp.155-166
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• 2001

This paper deals with the subsequence searching problem under time-warping. Our work is motivated by the observation that subsequence searches slow down quadratically as the average length of data sequences increases. To resolve this problem, the Segment-Based Approach for Subsequence Searches (SBASS) is proposed. The SBASS divides data and query sequences into a series of segments, and retrieves all data subsequences. Our segmentation scheme allows segments to have different lengths; thus we employ the time warping distance as a similarity measure for each segment pair. For efficient retrieval of similar subsequences, we extract feature vectors from all data segments exploiting their monotonically changing properties, and build a spatial index using feature vectors. The effectiveness of our approach is verified through extensive experiments.

• 정보처리학회논문지D
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• 제10D권2호
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• pp.261-266
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• 2003

단백질은 아미노산의 선형 중합체(linear polymer)로서 생체의 조직을 구성하고 각종 생화학 반응을 조절하는 역할을 하는 가장 중요한 생체 분자에 속한다. 이러한 단백질의 특성과 기능은 해당 단백질을 구성하는 아미노산의 서열에 의해 결정되기 때문에, 주어진 단백질의 서열을 알아내는 것은 단백질 기능 연구의 출발점이다. 본 논문은 기존의 생화학적 단백질 서열 결정 방법의 단점을 극복할 수 있는 데이터 마이닝 기반 단백질 서열 예측 기법을 제안한다. 복수개의 단백질 절단효소(protease)를 적용함으로써, 서로 중첩된 단백질 조각을 얻어내고, 각 조각의 질량 정보와 단백질 데이타베이스를 이용하여 후보 서열을 식별한다. 얻어진 후보 서열의 조립을 통해 전체 서열을 결정하기 위한, 다중 분할 그래프(multi-partite graph) 구축 및 경로 탐색 기법을 제안한다. 아울러, 대표적인 단백질 서열 데이타베이스인 SWISS-PROT을 이용한 실험을 통해 제안한 방법의 성능을 평가한다.

• 한국정보과학회논문지:데이타베이스
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• 제36권3호
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• pp.169-179
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• 2009

통신 기록 데이타는 이메일이나 인스턴스 메시지를 주고 받거나, 웹사이트에 접속하는 것과 같은 통신 이벤트들로 구성된다. 미국과 유럽연합을 포함한 여러 나라에서는 인터넷을 사용한 범죄의 조사와 발견을 위해서 통신 서비스 제공자에게 이런 데이타를 보관하도록 규정하고 있다. 보관되는 통신 기록 데이타의 크기가 매우 크기 때문에 치안당국이 이 데이타를 사용하기 위해서는 필요한 정보만을 효과적으로 추출해내는 방법이 필요하다. 본 논문에서는 발신자, 수신자, 통신발생시각의 세 가지 정보만 포함하는 통신 이벤트가 주어질 때, 의미 있는 정보 중 하나인 대화형 통신 순서열 패턴과 이러한 패턴의 마이닝 문제를 정의하고 것을 해결하기 위해 Fast Discovering Interactive Communication Sequence Patterns (FDICSP)라 불리는 알고리즘을 제안한다. FDICSP는 길이가 짧은 대화형 통신 순서열을 조합하여 길이가 긴 대화형 통신 순서열을 생성 해나가는데, 대화형 통신 순서열의 특성에 초점을 맞춘 작업을 통해 효율적으로 대화형 통신 순서열 패턴을 찾는다.

• Parasites, Hosts and Diseases
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• 제39권2호
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• pp.151-160
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• 2001

Randomly selected 435 clones from Acanthamoeba healyi cDNA library were sequenced and a total of 387 expressed sequence tags (ESTs) had been generated. Based on the results of BLAST search, 130 clones (34.4%) were identified as the genes enconding surface Proteins , enzymes for DNA, energy Production or other metabolism, kinases and phosphatases, protease, proteins for signal transduction, structural and cytoskeletal proteins, cell cycle related proteins, transcription factors, transcription and translational machineries, and transporter proteins. Most of the genes (88.5%) are newly identified in the genus Acanthamoeba. Although 15 clones matched the genes of Acanthamoeba located in the public databases, twelve clones were actin gene which was the most frequently expressed gene in this study. These ESTs of Acanthamoeba would give valuable information to study the organism as a model system for biological investigations such as cytoskeleton or cell movement, signal transduction, transcriptional and translational regulations. These results would also provide clues to elucidate factors for pathogenesis in human granulomatous amoebic encephalitis or keratitis by Acanthamoeba.

• Environmental Analysis Health and Toxicology
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• 제24권2호
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• pp.107-117
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• 2009

Metal pollution of aquatic ecosystems is a problem of economic and health importance. Information regarding molecular responses to metal exposure is sorely needed in order to identify potential biomarkers. To determine the effects of heavy metals on chironomids, the full-length cDNA of alcohol dehydrogenase (ADH3) from Chironomus riparius was determined through molecular cloning and rapid amplification of cDNA ends (RACE). The expression of ADH3 was analyzed under various cadmium and copper concentrations. A comparative and phylogenetic study among different orders of insects and vertebrates was carried out through analysis of sequence databases. The complete cDNA sequence of the ADH3 gene was 1134 bp in length. The sequence of C. riparius ADH3 shows a low degree of amino acid identity (around 70%) with homologous sequences in other insects. After exposure of C. riparius to various concentrations of copper, ADH3 gene expression significantly decreased within 1 hour. The ADH3 gene expression was also suppressed in C. riparius after cadmium exposure for 24 hour. However, the effect of cadmium on ADH3 gene expression was transient in C. riparius. The results show that the suppression of ADH3 gene by copper exposure could be used as a possible biomarker in aquatic environmental monitoring and imply differential toxicity to copper and cadmium in C. riparius larvae.