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3',4'7-Trihydroxyflavone in Albizzia julibrissin

  • Prapaipit-Chamsuksai;Choi, Jae-Sue;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • v.4 no.2
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    • pp.129-131
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    • 1981
  • From the steambark of Albizzia julibrissin, 3', 4' 7-trihydroxyflavone and .alpha.-spinasteryl-D-glucoside were isolated.

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A Lignan from Rubia akane

  • Han, Byung-Hoon;Park, Man-Ki;Park, Yeon-Hwa
    • Archives of Pharmacal Research
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    • v.13 no.3
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    • pp.289-291
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    • 1990
  • A lignan (+) isolariciresinol, was isolated from Rubia akane Nakai. This is the first reporting form Rubiaceae.

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Synthesis of Acyclonucleosides (4) - Synthesis of 3 ' -substituted secouridines4

  • Cho, Young-Hoon;Yang, Jae-Wook;Chun, Byung-Kwon;Kim, Moon-Hwan;Chun, Moon-Woo;Chung, Won-Keun
    • Archives of Pharmacal Research
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    • v.12 no.4
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    • pp.300-305
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    • 1989
  • The synthetic study of 3' azido and 3'-fluoro secouridines toward development of new antiviral agents is described. These acyclic nucleosides were synthesized from uridine by the method of ring opening reaction of sugar moiety.

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Ionophore Activity of Frangufoline

  • Park, Man-Ki;Park, Jeong-Hill;Cho, Jung-Hwan;Park, Jun-Kyu;Han, Yong-Nam;Han, Byung-Hoon
    • Archives of Pharmacal Research
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    • v.14 no.2
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    • pp.103-104
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    • 1991
  • The ionophore activity of frangufoline (1), a sedative cyclopeptide alkaloid isolated from Zizyphus jujuba, was investigated by UV and CD spectroscopic methods. Frangufoline (1) showed ion binding activity to calcium and magnesium ions.

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Total Synthesis of Sufentanil

  • Shin, Dong-Yun;Ryu, Jae-Sang;Hyun, Soon-Sil;Park, Hyun-Ju;Jeon, Ra-Ok;Suh, Young-Ger
    • Archives of Pharmacal Research
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    • v.22 no.4
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    • pp.398-400
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    • 1999
  • Sufentanil, a potent anilidopiperidine analgesic, was synthesized from a simple thiophenylethylamine via six sequence. The key parts of this synthesis involved an efficient construction of thiophenylethylpiperidone by aminomethano desilylation-cyclization followed by Swern oxidation and a direct regioselective N-nucleophilic spiral epoxide cleavage with aniline promoted by Lewis acids.

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