Synthetic Studies on Carbapenem and Penem Antibiotics(VI) Improved synthesis of (3S,4S)-4-acetoxy-3-phenylacetamido-azetidin-2-one

  • Oh, Eugene (Department of Chemistry, Seoul National University) ;
  • Lee, Youn-Young (Department of Chemistry, Seoul National University) ;
  • Goo, Yang-Mo (Department of Pharmacy, Seoul National University)
  • Published : 1988.06.01

Abstract

Penicillin G potassium salt was transformed in high yield to 4-acetoxy-3-phenylacetaminoazetidinone by treatment of mercury acetate, ozonolysis and methanol in sequence.

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