Ionophore Activity of Frangufoline

  • Park, Man-Ki (College of Pharmacy, Seoul National University) ;
  • Park, Jeong-Hill (College of Pharmacy, Seoul National University) ;
  • Cho, Jung-Hwan (College of Pharmacy, Seoul National University) ;
  • Park, Jun-Kyu (College of Pharmacy, Seoul National University) ;
  • Han, Yong-Nam (Natural Products Research Institute, Seoul National University) ;
  • Han, Byung-Hoon (Natural Products Research Institute, Seoul National University)
  • Published : 1991.06.01

Abstract

The ionophore activity of frangufoline (1), a sedative cyclopeptide alkaloid isolated from Zizyphus jujuba, was investigated by UV and CD spectroscopic methods. Frangufoline (1) showed ion binding activity to calcium and magnesium ions.

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