• Title/Summary/Keyword: Seoul archives

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Immunomodulating Activities of Brazilin in vitro

  • Moon, Chang-Kiu;Mock, Myung-Soo;Yang, Kyung-Mee;Han, Hye-Seung;Won, Hyeon-Soon;Kim, Ji-Young;Chung, Jin-Ho;Moon, Chang-Hyun
    • Archives of Pharmacal Research
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    • v.15 no.4
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    • pp.283-288
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    • 1992
  • This work was performed to investigate the effects of brazilin in vitro on mitrogen-induced proliferation, ConA-induced TCGF release and responsiveness to recombinant-induced proliferation, ConA-induced TCGF release and responsiveness to recombinant IL-2 using splenocytes from C57BL/6 female mice. Brazilin (29-80 ng/ml) caused a noticeable increase in TCGF production of splenocytes, but did not affect responsivness to recombinant IL-2, the expression of ConA-induced high affinity IL-2 receptor and mitogen-induced proliferation of splenocytes.

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CoMFA and CoMSIA 3D QSAR Studies on Pimarane Cyclooxygenase-2 (COX-2) Inhibitors

  • Lee, Kwang-Ok;Park, Hyun-Ju;Kim, Young-Ho;Seo, Seung-Yong;Lee, Yong-Sil;Moon, Sung-Hyun;Kim, Nam-Joong;Park, Nam-Song;Suh, Young-Ger
    • Archives of Pharmacal Research
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    • v.27 no.5
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    • pp.467-470
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    • 2004
  • Comparative molecular field analysis and comparative molecular similarity indices analysis were performed on twenty five analogues of pimarane COX-2 inhibitor to optimize their cyclooxygenase-2 (COX-2) selective anti-inflammatory activities.

A Study on the Tendencies and Characteristics When Constructing Landscape Architectural Archives in the US (미국 조경 아카이브 구축 동향과 특성 연구)

  • Lee, Myeong-Jun;Kim, Jung-Hwa;Seo, Young-Ai
    • Journal of the Korean Institute of Landscape Architecture
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    • v.47 no.6
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    • pp.1-11
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    • 2019
  • This study aims to understand the tendencies and characteristics when constructing landscape architectural archives in the United States, and to find implications for creating Korean landscape architectural archives. Focusing on seven American landscape architectural archives operated by public institutes, universities, and research institutes, this study examines the background, mission, scope, subject, acquisition, arrangement, and application of the programs in the archives. The results show that the characteristics of the American landscape architectural archives are as follows: first, the recognition of the value and importance of the landscape plays a major role in the establishment of archives; second, the purpose of the archives is to educate and encourage people to find diversity or significance of landscapes; third, the subject and scope of the archives vary according to the purpose of each operating institution; fourth, the main acquisitional method is to receive a donation and to purchase materials or documents; fifth, the classification systems of each archive differs depending on the subject and scope; and sixth, the archives were built on the basis of participation and collaboration with various experts and organizations with stable and sustainable financial resources. These characteristics offer three implications for constructing landscape architectural archives in Korea. First, a long-term vision for landscape architectural archives and the establishment of differentiated themes are required. Second, appropriate methods of material collection and systems of classification, recording, and digitization are necessary and therefore research and pilot archives are required. Third, it is necessary to secure the sustainability of archives by developing ways to utilize the archives in connection with academic and educational programs, thereby securing financial resources and allowing for the establishment of appropriate policies. As basic research, this study is significant as it provides a basis for further research concerning the development of landscape architectural archives in Korea.

Studies on the antioxidant components of Korean ginseng 3

  • Han, Byung-Hoon;Park, Myung-Hwan;Nam, Han-Yong
    • Archives of Pharmacal Research
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    • v.4 no.1
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    • pp.53-58
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    • 1981
  • The effective components of Korean ginseng showing the lipid-peroxide depressing activity were isolated. From the ether-soluble acidic fraction of fresh ginseng three phenolic acids were obtained. Salicylic acid and vanilic acid exhibited the potent antioxidant activity, where p-hydroxycinnamic acid did not.

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Effects of brazilin and haematoxylin on the lipidperoxidation in the rat liver mitochondria

  • Moon, Chang-Kiu;Ha, Bae-Jin;Lee, Chong-Chul
    • Archives of Pharmacal Research
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    • v.7 no.1
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    • pp.63-64
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    • 1984
  • This major sites of liquidperoxidation-damage within the cell are at biomembrances, especially those of subcellular organells such as mitochondria and microsomes whose membranes contain relatively large amount of polyunsaturated fatty acids. Mitochondria are the power plants of eukaryotic cells. Hence their damage by liquid peroxidation can profoundly affect cellular function.

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Coumarins and Triterpenoid Glycosides from the Roots of Patrinia scabiosaefolia

  • Choi, Jae-Sue;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • v.7 no.2
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    • pp.121-126
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    • 1984
  • From the roots of Patrinia scabiosaefolia Valerianaceae), scopoletin (1), esculetin (2), oleanonic acid (3), 3-O-.alpha.-L-rhamnopyranosyl (1.rarw.2)-.alpha.-l-arabinopyranosyl oleanolic acid (4) and 3-O-.alpha.-L- rhamnopyranosyl (1 .rarw. 2)-.alpha.-L-arabinopyranosyl header agenin (5) were isolated and characterized by spectral data.

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Two tetrahydroquinoline alkaloids from glycyrrhiza uralensis

  • Han, Young-Nam;Chung, Myung-Sook;Kim, Tae-Hee;Han, Byung-Hoon
    • Archives of Pharmacal Research
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    • v.13 no.1
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    • pp.101-102
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    • 1990
  • Two alkaloids were isolated from the roots of Glycyrrhiza uralensis Fisch. They were identified as 5, 6, 7, 8-tetrahydro-2, 4-dimethylquinoline (1) and 5, 6, 7, 8-tetrahydro-4-methylquinoline (2) by spectral data. The isolation of alkaloid from glycyrrhiza species is reported for the first time.

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Acetonylidene americanin A, An artefact isolated from phytolacca americana

  • Woo, Won-Sick;Kang, Sam-Sik;Otto-Seligmann;Wagner, Hildebert
    • Archives of Pharmacal Research
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    • v.5 no.1
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    • pp.1-5
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    • 1982
  • From the seeds of Phytolacca americana, acentonylidene americanin. A was isolated and its structure elucidated mainly by spectroscopic methods. This compound is not a genuine constituent but formed in the tissue on heating with acetone.

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