• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5245-5247
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• 2014

Background: Helicobacter pylori (H.pylori) is one of the most important causes of dyspepsia and gastric cancer and diagnosis can be made by invasive or non-invasive methods. The Atlas Helicobacter pylori antigen test is a new rapid non-invasive method which is simple to conduct. The aim of this study was to determine its sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy. Materials and Methods: This prospective study was conducted between July 2012 and December 2013. Stool samples of 59 dyspeptic patients who underwent upper endoscopy were evaluated for H. pylori stool antigen. Results: From the 59 patients who participated in this study, there were 36 (61%) males and 23 (39%) females. H. pylori was diagnosed in 24 (40.7%) gastric biopsies, 22 (91.7 %) of these being positive for the Atlas H. pylori antigen test. The sensitivity, specificity, PPV, NPV and accuracy were 91.7%, 100%, 100%, 94.6% and 96.6% respectively. Conclusions: The Atlas H. pylori antigen test is a new non-invasive method which is simple to perform and avails reliable results in a few minutes. Thus it can be the best option for the diagnosis of H. pylori infection due to its high sensitivity and specificity.

• Tuberculosis and Respiratory Diseases
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• 제84권3호
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• pp.226-236
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• 2021

Background: Although the Quidel Sofia rapid influenza fluorescent immunoassay (FIA) is widely used to identify influenza A and B, the diagnostic accuracy of this test remains unclear. Thus, the objective of this study was to determine the diagnostic performance of this test compared to reverse transcriptase-polymerase chain reaction. Methods: A systematic literature search was performed using MEDLINE, EMBASE, and the Cochrane Central Register. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), and a hierarchical summary receiver-operating characteristic curve (HSROC) of this test for identifying influenza A and B were determined using meta-analysis. A sensitivity subgroup analysis was performed to identify potential sources of heterogeneity within selected studies. Results: We identified 17 studies involving 8,334 patients. Pooled sensitivity, specificity, and DOR of the Quidel Sofia rapid influenza FIA for identifying influenza A were 0.78 (95% confidence interval [CI], 0.71-0.83), 0.99 (95% CI, 0.98-0.99), and 251.26 (95% CI, 139.39-452.89), respectively. Pooled sensitivity, specificity, and DOR of this test for identifying influenza B were 0.72 (95% CI, 0.60-0.82), 0.98 (95% CI, 0.96-0.99), and 140.20 (95% CI, 55.92-351.54), respectively. The area under the HSROC for this test for identifying influenza A was similar to that for identifying influenza B. Age was considered a probable source of heterogeneity. Conclusion: Pooled sensitivities of the Quidel Sofia rapid influenza FIA for identifying influenza A and B did not quite meet the target level (≥80%). Thus, caution is needed when interpreting data of this study due to substantial betweenstudy heterogeneity.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1651-1655
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• 2012

Background: Our aim was to investigate the efficacy of the Pap test in combination with the ThinPrep cytological test (TCT) in screening for cervical cancer in China. Design: From March 2006 to October 2008, 988 women with the mean age $46.4{\pm}10.5$ years (range, 23-80 years) were recruited to receive cervical cancer screening. Pap test results ${\geq}$ grade III and TCT findings ${\geq}$ ASCUS/AGUS were considered abnormal. Subjects with a Pap test result ${\geq}$ grade IIb received TCT. Colposcopy and biopsies were performed in all participants, and final diagnosis was based on pathological findings. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and Youden index for predicting CIN I or above were determined. Results: The sensitivity, specificity, PPV, NPV and Youden index of the Pap test were 43.1%, 97.2%, 70.0%, 91.9%, and 40.3%, respectively. The same values for TCT in predicting CIN were 80.0%, 63.2%, 16.0%, 97.3%, and 43.2%, respectively. The two tests in combination gave values for predicting CIN of 64.8%, 87.6%, 43.6%, 94.4%, and 53.5%, respectively. Combined testing exhibited the highest Youden index (53.4%). Conclusion: The Pap test with a reduced threshold in combination with the TCT has high sensitivity and high specificity in screening for cervical cancer.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.326-331
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• 2006

The durability of recent motors is longer than the past one because there are the rapid technique development of the automobile industry and the vehicle maintenance of users. And then the importance of the durability test due to vibration is increased from day to day. So full vehicle and parts companies accomplish the durability test using various methods. The most public test method among them is the reliable field test but it bring on higher cost and period of the development process. The durability test using MAST(multi axis simulation table) is a solution in order to improve the development process of automobiles. Generally its excitation source uses the optimized road profiles that are obtained by the road test of belgian road, country road, cobbleston road and so on instead of a real field but the interrelations and influences accordingly vehicle damage are considered by a field test between specific roads and real fields in the first place. Therefore this study, in order to accomplish a basic research for the durability test using the MAST, performed on the real field driving test at various domestic roads and the results which are analyzed by PSD(power spectrum density) are compared with relative sensitivity among the roads. Consequently they can present a basic material for generation of road profiles which is applied to the durability test using MAST.

• The Journal of Korean Physical Therapy
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• 제35권3호
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• pp.57-63
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• 2023

Purpose: The aim of this study was to conduct a systematic review of randomized controlled studies from 2012 to present that explore the diagnostic accuracy of clinical tests used for diagnosing anterior cruciate ligament (ACL) injury. Methods: Study design: Systematic review. Literature search of the PubMed and Scholar databases was conducted using keywords related to diagnostic accuracy of clinical tests for ACL injury. The PRISMA Guidelines were followed to conduct this study. The Cochrane Risk of Bias Tool was utilized to assess the quality of each included study. Results: As a result, 8 studies were included, and 6 clinical tests used in ACL tears were evaluated for diagnostic accuracy. The pivot shift test was reported as having the highest +LR (29.5) value with a sensitivity of 59% and a specificity of 98%. However, the test with the lowest -LR value was the lever test, and the values were as follows: -LR (0.08), +LR (4.7), specificity (80%), sensitivity (94%). Conclusion: In this study, it was concluded that a single clinical test is not sufficient to determine the presence of ACL injury. Test combinations have a higher diagnostic accuracy than a single test. In this study, the accuracy of the clinical tests was examined without considering the amount of ACL rupture and acute-chronic condition. Further research is required to examine the impact of these two factors on diagnostic accuracy of clinical test.

• 지질공학
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• 제4권3호
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• pp.311-319
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• 1994

본 논문은 누수를 포함하는 프락탈 대수층의 수리상수의 최적값을 구하기 위한 민감성 분석에 대한 것이다. 민감성 분석은 최소자승법을 이용한다. 민감성 분석에 의하여 수리상수(일반화 투수량계수와 일반화 저유계수)는 여러가지 흐름의 차원과 여러 값의 누수계수에 대해서 쉽게 결정될 수 있다. 아울러, 민감성, 분석은 다수의 양수정의 다단계 양수에도 적용되었다. 민감성 분석을 이용한 프락탈 대수층의 수리상수 산출을 위하여 컴퓨터 프로그램이 개발되었다.

• Nuclear Engineering and Technology
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• 제30권4호
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• pp.287-297
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• 1998

The elastic stiffness formula of leaf type holddown spring(HDS) assembly is verified by comparing the values of elastic stiffness with the characteristic test results of the HDS's specimens. The comparisons show that the derived elastic stiffness formula is useful in reliably estimating the elastic stiffness of leaf type HDS assembly. The elastic stiffness sensitivity of leaf type HDS assembly is analyzed using the formula and its gradient vectors obtained from the mid-point formula. As a result of sensitivity analysis, the elastic stiffness sensitivity with respect to each design variable is quantified and design variables of large sensitivity are identified. Among the design variables, leaf thickness is identified as the most sensitive design variable to the elastic stiffness of leaf type HDS assembly. In addition, the elastic stiffness sensitivity, with respect to design variable, is in power-law type correlation to the base thickness of the leaf.

• 한국자동차공학회논문집
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• 제8권2호
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• pp.129-137
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• 2000

In the prototype stage of a car developing program, the efficiency of trouble shooting is an important factor to be considered. Structural modifications by the design sensitivity analysis are applied to a steering wheel system for improving the idle vibration of the prototype passenger car. For the design sensitivity analysis, the experimental modal analysis for the steering system attached to a body-in-white is fulfilled and the modal parameters extracted from the experimental data are used to predict the effect of structural modification, The design sensitivity results rank the locations to be reinforced in terms of frequency variation. The modification of steering system according to the sensitivity analysis results shifted the resonant frequency of the system effectively. In addition, the idle test of the car after the structural modifications f steering system shows that the proposed method can reduce vibration of the steering wheel efficiently.

• 한국보육지원학회지
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• 제14권6호
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• pp.1-18
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• 2018

Objective: The purpose of this study was to investigate relationships among child care teachers' role conflict, organizational commitment and teacher's sensitivity. It also aimed to test the mediating effect of organizational commitment on the pathway from child care teachers' role conflict on teacher's sensitivity. Methods: A self-report survey was conducted on 301 child care teachers in Chungbuk. Descriptive, means, standard deviations, correlations using SPSS 18.0, and Structural Equation Modeling using AMOS 18.0 were all conducted in order to analyze the collected data. Results: The results indicated that child care teachers' role conflict and organizational commitment had significant direct effects on teacher's sensitivity. This study also confirmed the significant mediating role of organizational commitment on the pathway from child care teachers' role conflict to sensitivity. Conclusion/Implications: The significance of role conflict and organizational commitment suggests that the integration of individuals with less conflict and more dedication will contribute more qualitative child care services by improving sensitive interactions with young children.

• 한국의료질향상학회지
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• 제22권2호
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• pp.27-40
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• 2016

Purpose: Globally, falls are a major public health problem. The study aimed to evaluate the predictive validity of the Timed Up and Go test (TUGT) as a screening tool for fall risk. Methods: An electronic search was performed Medline, EMBASE, CINAHL, Cochran Library, KoreaMed and the National Digital Science Library and other databases, using the following keywords: 'fall', 'fall risk assessment', 'fall screening', 'mobility scale', and 'risk assessment tool'. The QUADAS-II was applied to assess the internal validity of the diagnostic studies. Thirteen studies were analyzed using meta-analysis with MetaDisc 1.4. Results: The selected 13 studies reporting predictive validity of TUGT of fall risks were meta-analyzed with a sample size of 1004 with high methodological quality. Overall predictive validity of TGUT was as follows. The pooled sensitivity 0.72 (95% confidence interval [CI]: 0.67-0.77), pooled specificity 0.58 (95% CI: 0.54-0.63) and sROC AUC was 0.75 respectively. Heterogeneity among studies was a moderate level in sensitivity. Conclusion: The TGUT's predictive validity for fall risk is at a moderate level. Although there is a limit to interpret the results for heterogeneity between the literature, TGUT is an appropriate tool to apply to all patients at a potential risk of accidental fall in a hospital or long-term care facility.