• Journal of Korean Philosophical Society
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• v.143
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• pp.215-244
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• 2017

It is said that we live in an age of technology. And indeed, science and technology do play key roles to our life of happiness, but they are equally central in all events that threaten it. Science and technology are the means we often turn to in seeking solutions to our problems, and in turn are often the apparent sources of new problems. Thus it is not surprising that they have two aspects at the same time. CCTV has been presented to us as a technical solution to security problems. With the help of CCTV, we can more effectively prevent, detect, and prosecute crimes. With the help of CCTV, both public and private spaces can be made more secure. But of course, CCTV also has a down side. The down side most prominently anticipated has been loss of privacy and proliferation of surveillance. It is largely this potential problem with CCTV that has been regulated against. It is said that one reason for imposing a limitation on individual privacy is the societal interest in the prevention of crime. Accordingly a balance between the need to prevent crime through the use of CCTV and the duty to respect the privacy interests of individual citizens is in need of redress. In other hand, two theories of socio-political philosophy may have provided useful ways of understanding the role of CCTV in contemporary society. Firstly, neo-Marxist frameworks, for instance, stress the use of CCTV to police existing unequal socioeconomic divisions within society and the dominance of particular forms of order based upon materialist agendas. Secondly, Foucauldian frameworks contend that Foucault's notion of panoptic surveillance underpinning (self) disciplinary society is an appropriate template for understanding CCTV in late-modern society. In order to find a new point of valance between security and privacy in the use of CCTV, the participation of each citizen in the discourse to make the new norm is necessary. And to prevent its political misuse, their surveillance, or check for the potential surveillance-power is required.

• (The) Korean Journal of Educational Psychology
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• v.31 no.3
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• pp.563-587
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• 2017

The purpose of this study was to understand the ways to enhance academic help-seeking by analyzing the structural relations among individual(achievement goal orientation) and contextural (teacher behaviors and classroom climate) factors known to affect help-seeking, one of the effective self-regulated learning strategies, for upper elementary students. More specifically, it explored the mediational roles of general classroom climate and student achievement goal orientation in the relation between supportive teacher behaviors and student academic help-seeking. A survey was administered to 315 fifth- or sixth-grade students in three elementary schools and the data from the survey was analyzed. Main results are as follows. First, supportive and learning-oriented teacher behaviors with high expectation related to more cohesive and positive classroom climate and more adaptive achievement goal such as mastery goal. Positive classroom climate played an important role in improving student mastery goal, and only mastery goal among different types of achievement goal orientation had a positive prediction of student help-seeking. Second, teacher behaviors significantly predicted student help-seeking through a double mediation of classroom climate and student mastery goal, which showed that classroom contextual factors and student individual factors interacted for help-seeking. These results suggest that the role of teachers as well as the mastery goal of students are important for enhancing students' help-seeking behavior as an adaptive learning strategy.

• Animal Bioscience
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• v.34 no.8
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• pp.1392-1402
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• 2021

Objective: The growth rate of pigs is related to differentiation and proliferation of muscle cells, which are regulated by growth factors and expression of growth-related genes. Thus, the objective of this study was to establish optimal culture conditions for Jeju black pig (JBP) muscle cells and determine the relationship of various factors involved in muscle growth with the proliferation of JBP muscle cells. Methods: Muscles were taken from the femur skeletal muscle of JBP embryos. After isolation of the muscle cells, cells were cultured in a 6-well plate under four different culture conditions to optimize culture conditions for JBP muscle cells. To analyze proliferation rate of JBP muscle cells, these muscle cells were seeded into 6-well plates at a density of 1.5×10⁵ cells per well and cultured for 3 days. Western blot and quantitative real-time polymerase chain reaction were applied to verify the myogenic differentiation 1 (MyoD) expression and growth-related gene expression in JBP muscle cells, respectively. Results: We established a muscle cell line from JBP embryos and optimized its culture conditions. These muscle cells were positive for MyoD, but not for paired box 7. The proliferation rate of these muscle cells was significantly higher in a culture medium containing bFGF and epidermal growth factor + basic fibroblast growth factor (EGF+bFGF) than that without a growth factor or containing EGF alone. Treatment with EGF and bFGF significantly induced the expression of MyoD protein, an important transcription factor in muscle cells. Moreover, we checked the changes of expression of growth-related genes in JBP muscle cells by presence or absence of growth factors. Expression level of collagen type XXI alpha 1 gene was changed only when EGF and bFGF were added together to culture media for JBP muscle cells. Conclusion: Concurrent use of EGF and bFGF increased the expression of MyoD protein, thus regulating the proliferation of JBP muscle cells and the expression of growth-related genes.

• Journal of Ginseng Research
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• v.45 no.1
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• pp.134-148
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• 2021

Background: Lung cancer has a high incidence worldwide, and most lung cancer-associated deaths are attributable to cancer metastasis. Although several medicinal properties of Panax ginseng Meyer have been reported, the effect of ginsenosides Rk1 and Rg5 on epithelial-mesenchymal transition (EMT) stimulated by transforming growth factor beta 1 (TGF-β1) and self-renewal in A549 cells is relatively unknown. Methods: We treated TGF-β1 or alternatively Rk1 and Rg5 in A549 cells. We used western blot analysis, real-time polymerase chain reaction (qPCR), wound healing assay, Matrigel invasion assay, and anoikis assays to determine the effect of Rk1 and Rg5 on TGF-mediated EMT in lung cancer cell. In addition, we performed tumorsphere formation assays and real-time PCR to evaluate the stem-like properties. Results: EMT is induced by TGF-β1 in A549 cells causing the development of cancer stem-like features. Expression of E-cadherin, an epithelial marker, decreased and an increase in vimentin expression was noted. Cell mobility, invasiveness, and anoikis resistance were enhanced with TGF-β1 treatment. In addition, the expression of stem cell markers, CD44, and CD133, was also increased. Treatment with Rk1 and Rg5 suppressed EMT by TGF-β1 and the development of stemness in a dose-dependent manner. Additionally, Rk1 and Rg5 markedly suppressed TGF-β1-induced metalloproteinase-2/9 (MMP2/9) activity, and activation of Smad2/3 and nuclear factor kappa B/extra-cellular signal regulated kinases (NF-kB/ERK) pathways in lung cancer cells. Conclusions: Rk1 and Rg5 regulate the EMT inducing TGF-β1 by suppressing the Smad and NF-κB/ERK pathways (non-Smad pathway).

• Journal of the Korea Convergence Society
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• v.12 no.3
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• pp.247-259
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• 2021

This study aimed to look for educational ways to prepare for the future society for education and people of talent who will lead the post-COVID-19 era. To this end, the factors necessary for the type of future talent in the post-COVID-19 era were identified by analyzing Big data. Based on the deducted factors composing the type of talent in the post-COVID-19 era, policy direction according to the emergence of the post-COVID-19 era were deducted through the interviews with the group of experts and delphi survey, and on the basis of this, this study sought for"a plan for the educational change in line with cultivation of people of talent in the post-COVID-19 era. The results of this study are as follows. First, through the big data analytics and analysis of the interviews, convergence, ICT utilization ability, creativity, self-regulated competency and leadership were found to be the factors necessary for the type of talent in the post-COVID-19 era. Second, it considered the innovation of digital education system and the support for vulnerable classes as the issue for cultivation of people of talent in the post-COVID-19 era. Third, the most important policy with regard to the educational direction for cultivation of people of talent in the post-COVID-19 era was cultivation of convergence talents. Convergence is a very important variable in the post-COVID-19 era since it creates new values by connecting things that are separated from each other. Hopefully, this study will build a basis for competency development, education and training in preparation for the post-COVID-19 era.

• Korean Chemical Engineering Research
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• v.61 no.1
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• pp.68-73
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• 2023

Smoke masks have attracted great interests and have been supplied widely for the improvement of the safety during fire evacuation. However, there is not sufficient research on the practical utility, certification status and easy-donning about commercial smoke masks, therefore it is difficult to determine the actual usefulness of the smoke masks. In this study, we conducted a survey on users' perceptions and experiences about the smoke masks, and investigated the status of certification of 54 commercial smoke masks. We also performed donning tests and examined degrees of discomfort for 4 types of the smoke masks. Although 22% of 235 respondents had experienced the smoke masks before the test, and 23% of the respondents did not know the smoke masks, 93% of the respondents expected that the smoke masks could protect users from fire smokes and toxic gases. It was found that 41% of the commercial smoke masks did not certify according to domestic or overseas performance standards. Most certification standards have not effectively regulated maximum wearing time for the smoke masks. Only ASTM E 2952 and KFIS 024 had specific standards for the maximum wearing time of 30 s. As a result of donning tests for 4 types of smoke masks, the wearing time of the hood-type mask and self-contained smoke mask exceeded 30 s, therefore these types of smoke masks might increase the required safe evacuation time. On the other hand, it was also found that short education about the donning could reduce the wearing time by 19% and numbers of improper wearing by 89%.

• Journal of Intelligence and Information Systems
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• v.29 no.2
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• pp.285-301
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• 2023

Due to the increasing demand and importance of non-face-to-face education, open online learning platforms are getting interests both domestically and internationally. These platforms exhibit different characteristics from online courses by universities and other educational institutions. In particular, students engaged in these platforms can receive more learner autonomy, and the development of tools to assist learning is required. From the past, researchers have attempted to utilize process mining to understand realistic study behaviors and derive learning patterns. However, it has a deficiency to employ it to the open online learning platforms. Moreover, existing research has primarily focused on the process model perspective, including process model discovery, but lacks a method for the process pattern and instance perspectives. In this study, we propose a method to identify learning patterns within an open online learning platform using process mining techniques. To achieve this, we suggest three different viewpoints, e.g., model-level, variant-level, and instance-level, to comprehend the learning patterns, and various techniques are employed, such as process discovery, conformance checking, autoencoder-based clustering, and predictive approaches. To validate this method, we collected a learning log of machine learning-related courses on a domestic open education platform. The results unveiled a spaghetti-like process model that can be differentiated into a standard learning pattern and three abnormal patterns. Furthermore, as a result of deriving a pattern classification model, our model achieved a high accuracy of 0.86 when predicting the pattern of instances based on the initial 30% of the entire flow. This study contributes to systematically analyze learners' patterns using process mining.

• The Journal of the Convergence on Culture Technology
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• v.9 no.2
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• pp.525-531
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• 2023

In Korea, which is entering a super-aged society, the number of elderly patients who have difficulty walking independently is expected to increase rapidly, and it is necessary to develop wheelchair products with various functions to improve the quality of life of people with walking disabilities. Recently, wheelchair power assist devices that provide propulsion power by being attached to a manual wheelchair has been developed and is entering the domestic and global markets. In this study, we compared and analyzed the process of obtaining medical device certification for wheelchair power assist devices in Korea, the United States, and Europe. In Korea, a Class 2 medical device certification process was developed in 2021, and in the US FDA, it corresponds to Class 2 like the existing electric wheelchair and must pass the 510k certification process. In the case of Europe, it is uniquely regulated as Class I, and the CE mark can be attached through a relatively easy self-declaration of conformity. The Korean medical device industry, which is struggling with MDR certification, a new European medical device regulation, should pay attention to the relatively easy entry into the global market for wheelchair power assist products.

• Journal of Korea Entertainment Industry Association
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• v.13 no.5
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• pp.155-165
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• 2019

The sense of happiness of early childhood teachers has a great influence not only on teaching but also on infants. The purpose of this research is to investigate how prospective pre-service teachers' sense of happiness influence their teacher professionalism and teacher efficacy. The subjects were 264 pre-service teachers' in Gwangju metropolitan city and Jeollanamdo province. Statistical analysis of this study was done by Pearson's correlation coefficient and multiple regression analysis using SPSS WIN 22.0 program. The results of this study were as follows. First, there were significant positive relationships among the sense of happiness on teacher professionalism and teacher efficacy. There was a significant positive correlation between external happiness, inner happiness, and self-regulated happiness, which are indicating that there is a meaningful correlation between pre-service teachers' sense of happiness, teacher professionalism and teacher efficacy. Second, the sense of happiness was an important factor for predicting the teacher professionalism and teacher efficacy of pre-service early childhood teachers. The results of this study show that the pre - service teacher 's sense of happiness is a predictor variable that positively affects teacher professionalism and teacher efficacy. In conclusion, It is meaningful in seeking ways to improve teacher education by enhancing the euphoria of prospective pre-service teachers during school life and strengthening positive aspects of the educational contents and processes of the institutions that train infant teachers.

• Animal Bioscience
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• v.37 no.3
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• pp.471-480
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• 2024

Objective: The objective of this study was to investigate the regulation relationship of Ten-eleven translocation 1 (Tet1) in DNA demethylation and the proliferation of primordial germ cells (PGCs) in chickens. Methods: siRNA targeting Tet1 was used to transiently knockdown the expression of Tet1 in chicken PGCs, and the genomic DNA methylation status was measured. The proliferation of chicken PGCs was detected by flow cytometry analysis and cell counting kit-8 assay when activation or inhibition of Wnt4/β-catenin signaling pathway. And the level of DNA methylation and hisotne methylation was also tested. Results: Results revealed that knockdown of Tet1 inhibited the proliferation of chicken PGCs and downregulated the mRNA expression of Cyclin D1 and cyclin-dependent kinase 6 (CDK6), as well as pluripotency-associated genes (Nanog, PouV, and Sox2). Flow cytometry analysis confirmed that the population of PGCs in Tet1 knockdown group displayed a significant decrease in the proportion of S and G2 phase cells, which meant that there were less PGCs entered the mitosis process than that of control. Furthermore, Tet1 knockdown delayed the entrance to G1/S phase and this inhibition was rescued by treated with BIO. Consistent with these findings, Wnt/β-catenin signaling was inactivated in Tet1 knockdown PGCs, leading to aberrant proliferation. Further analysis showed that the methylation of the whole genome increased significantly after Tet1 downregulation, while hydroxyl-methylation obviously declined. Meanwhile, the level of H3K27me3 was upregulated and H3K9me2 was downregulated in Tet1 knockdown PGCs, which was achieved by regulating Wnt/β-catenin signaling pathway. Conclusion: These results suggested that the self-renewal of chicken PGCs and the maintenance of their characteristics were regulated by Tet1 mediating DNA demethylation through the activation of Wnt4/β-catenin signaling pathway.