• Title/Summary/Keyword: Self-diagnostic

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Design of Fluorescence Multi-cancer Diagnostic Sensor Platform based on Microfluidics (미세 유체 기반의 형광 다중 암 진단 센서 플랫폼 설계)

  • Lee, B.K.;Khaliq, A.;Jeong, M.Y.
    • Journal of the Microelectronics and Packaging Society
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    • v.29 no.4
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    • pp.55-61
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    • 2022
  • There is a major interest in diagnostic technology for multiple cancers worldwide. In order to reduce the difficulty of cancer diagnosis, a liquid biopsy technology based on a microfluidic device using trace amounts of biofluids such as blood is being studied. And optical biosensing, which measures the concentration of analytes through fluorescence imaging using biofluids, requires various strategies to improve sensitivity, and specialists and equipment are needed to carry out these strategies. This leads to an increase in diagnostic and production costs, and it is necessary to develop a technology to solve this problem. In this paper, we design and propose a fluorescent multi-cancer diagnostic sensing platform structure that implements passive self-separation technology and molecular recognition activation functions by fluid mixing, only with the geometry and microfluidic phenomena of microchannels based on self-driven flow by capillary force. In order to check the parameters affecting the performance of the plasma separation part of the designed sensor, the hydrodynamic diameter of the channel and the viscosity of the fluid were set as variables to confirm the formation of plasma separation flow through simulation. And finally, we propose an optimal sensor platform structure.

Reducing Medical Errors : Patients' Self Protect Behaviors and Involvement in Decision Making (의료과오 감소를 위한 환자의 자기보호행동 및 의사결정 참여)

  • An Kyung-Eh;Kim Jeong-Eun;Kang Kim Min-Ah;Jung Yoen-Yi
    • Health Policy and Management
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    • v.16 no.3
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    • pp.70-85
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    • 2006
  • The purposes of this study were (1) to describe patients' behaviors to protect themselves from medical errors and their involvement in decision making on the diagnostic and treatment procedures (2) to examine whether patients' characteristics, such as age, sex, education, experience of hospitalization and/or surgery influence their self protect behaviors and involvement in decision making on the diagnostic and treatment procedures. A survey was conducted with 99 patients visited one university hospital in Seoul, Korea. A 20-item questionnaire, a 4-point Likert scale, was used to measure the degree of patients' active involvement in decision making; patients' self protect behaviors regarding medication, hospitalization, and surgery; and communication (Cronbach's alpha=0.801). SPSS 12.0 was used for the descriptive and correlation analysis. Only 6.1% of the participants were involved in the decision making process for the diagnostic tests and treatment. More patients did self-protect behaviors associated with the medication than other areas but widely varied from 18.2 to 94.3 % among various items. More people with age of 60 or older compared to people in younger age groups reported more protect behaviors particularly associated with medication. Patient education is needed to improve their active role in preventing medical errors and to promote patients' safety.

Relationships between Intermittent Locking History and Self-Reported Bruxism in Temporomandibular Joint

  • Lee, Myeong-Ok;Lee, Yeon-Hee;Kang, Soo-Kyung;Chun, Yang-Hyun;Hong, Jung-Pyo;Auh, Q-Schick
    • Journal of Oral Medicine and Pain
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    • v.42 no.2
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    • pp.29-34
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    • 2017
  • Purpose: To evaluate aggravating factors of intermittent locking among temporomandibular joint using magnetic resonance imaging (MRI) and diagnostic criteria for temporomandibular disorder (DC/TMD) diagnosis. Methods: A retrospective analysis was conducted of 35 patients with intermittent locking history but normal intra-articular findings between September 2012 and June 2015 in Kyung Hee University Dental Hospital. A standardized DC/TMD assessment was performed on subjects with MRI findings. Clinical findings were assessed on the basis of maximum mouth opening (active & passive), self-reported habits, patients' age, gender, systemic diseases at the initial visit. First, chi square test was used to examine differences with variables and then risk factors for intermittent locking were assessed using multivariate logistic regression. Results: Self-reported bruxism was strongly associated with intermittent locking history. Conclusions: The new DC/TMD protocol is intended for use within any clinical setting and supports the full range of diagnostic activities from screening to definitive evaluation and diagnosis. Self-reported sleep bruxism has been associated with a higher likelihood of intermittent locking. Comorbidity is therefore a factor that must be assessed. It is necessary to consider the amount of contact of the teeth and the duration.

Nucleic acid-based molecular diagnostic testing of SARS-CoV-2 using self-collected saliva specimens

  • Hwang, Eurim C.;Kim, Jeong Hee
    • International Journal of Oral Biology
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    • v.46 no.1
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    • pp.1-6
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    • 2021
  • Since the outbreak of coronavirus disease 2019 (COVID-2019), the infection has spread worldwide due to the highly contagious nature of severe acute syndrome coronavirus (SARS-CoV-2). To manage SARS-CoV-2, the development of diagnostic assays that can quickly and accurately identify the disease in patients is necessary. Currently, nucleic acid-based testing and serology-based testing are two widely used approaches. Of these, nucleic acid-based testing with quantitative reverse transcription-PCR (RT-qPCR) using nasopharyngeal (NP) and/or oropharyngeal (OP) swabs is considered to be the gold standard. Recently, the use of saliva samples has been considered as an alternative method of sample collection. Compared to the NP and OP swab methods, saliva specimens have several advantages. Saliva specimens are easier to collect. Self-collection of saliva specimens can reduce the risk of infection to healthcare providers and reduce sample collection time and cost. Until recently, the sensitivity and accuracy of the data obtained using saliva specimens for SARS-CoV-2 detection was controversial. However, recent clinical research has found that sensitive and reliable data can be obtained from saliva specimens using RT-qPCR, with approximately 81% to 95% correspondence with the data obtained from NP and OP swabs. These data suggest that self-collected saliva is an alternative option for the diagnosis of COVID-19.

Practices for Readiness of Future Specialists for Professional Self-Determination in the Information Society

  • Olena Kochubei;Mykola Dubinka;Inna Knysh;Ihor Poliakov;Olga Tsokur;Vasyl Tiahur;Oleksandr Kuchai
    • International Journal of Computer Science & Network Security
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    • v.23 no.12
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    • pp.129-136
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    • 2023
  • Professional self-determination of the individual is a complex and lengthy process of finding and realizing yourself in the profession. The main goal of professional self-determination is clarified. The basic concepts of readiness for professional self-determination of future specialists in the modern information society are revealed. The following approaches to the consideration of the concept of readiness are defined: functional-psychological, personal, activity-based. Based on the components of readiness identified by the researchers, it can be assumed that the structure of professional self-determination of the future specialist contains motivational, cognitive and activity components. Self-determination is defined as a multidimensional process that can be considered from different points of view: as a series of tasks, that society sets for the emerging individual, and which the individual must solve in a certain period. As a process of step-by-step decision-making, with the help of which the individual forms a balance between his desires and inclinations, on the one hand, and the needs of society, on the other; as a process of forming an individual lifestyle, part of which is professional activity. A number of tasks of professional self-determination of a future specialist in the information society are formulated. Diagnostic practices for determining the degree of readiness of future specialists for future professional success are characterized. Practices are developed as a basis for creating an individually oriented correctional and development program to promote the formation of future specialists' focus on future professional success. Their task is to ensure control over the dynamics of this process, assess the effectiveness of this career guidance work. Practices are aimed at identifying the degree of thorough knowledge of the conditions for achieving professional success in the chosen field of activity among future specialists.

Treatment of Internal Carotid Artery Dissections with Endovascular Stent Placement: Report of Two Cases

  • Deok Hee Lee;Seung Ho Hur;Hyeon Gak Kim;Seung Mun Jung;Dae Sik Ryu;Man Soo Park
    • Korean Journal of Radiology
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    • v.2 no.1
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    • pp.52-56
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    • 2001
  • Extracranial carotid artery dissection may manifest as arterial stenosis or occlusion, or as dissecting aneurysm formation. Anticoagulation and/or antiplatelet therapy is the first-line treatment, but because it is effective and less invasive than other procedures, endovascular treatment of carotid artery dissection has recently attracted interest. We encountered two consecutive cases of trauma-related extracranial internal carotid artery dissection, one in the suprabulbar portion and one in the subpetrosal portion. We managed the patient with suprabulbar dissection using a self-expandable metallic stent and managed the patient with subpetrosal dissection using a balloon-expandable metallic stent. In both patients the dissecting aneurysm disappeared, and at follow-up improved luminal patency was observed.

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The Effect of the Problem-Based Learning on Critical Thinking Disposition, Academic Self-Efficacy and Self-Leadership of Nursing Students -Diagnostic Tests and Nursing- (문제중심학습(Problem- Based Learning)이 간호대학생의 비판적 사고성향, 학업적 자기효능감 및 셀프리더십에 미치는 효과 -진단검사와 간호 교과목 중심으로-)

  • Lee, Oi-Sun
    • Journal of Digital Convergence
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    • v.18 no.5
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    • pp.279-285
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    • 2020
  • Purpose :This study intends to test the effects of Problem-based learning on critical thinking disposition, academic self-efficacy and self-leadership for undergraduate nursing students. Methods: A one group pre-post design was applied to four diagnostic test and nursing for 4 times(eight hours) of 26 nursing students. Data were collected between August 29 and December 10, 2019. Data were analyzed by frequencies, Kolmogorov-Smirnov, paried t-test, Wilcoxon signed-rank test using SPSS/WIN 23.0. Results: Problem-based learning was significantly increasing critical thinking disposition(t=-2.16, p=.041) and Academic self-efficacy(z=-2.36, p=.018), but self-efficacy(t=-.16, p=.875) was no significantly. Conclusion: Based on this study, it is suggested that nursing students should develop their core competency by applying problem-based learning to various subject

A Flexible Programmable Memory BIST for Embedded Single-Port Memory and Dual-Port Memory

  • Park, Youngkyu;Kim, Hong-Sik;Choi, Inhyuk;Kang, Sungho
    • ETRI Journal
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    • v.35 no.5
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    • pp.808-818
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    • 2013
  • Programmable memory built-in self-test (PMBIST) is an attractive approach for testing embedded memory. However, the main difficulties of the previous works are the large area overhead and low flexibility. To overcome these problems, a new flexible PMBIST (FPMBIST) architecture that can test both single-port memory and dual-port memory using various test algorithms is proposed. In the FPMBIST, a new instruction set is developed to minimize the FPMBIST area overhead and to maximize the flexibility. In addition, FPMBIST includes a diagnostic scheme that can improve the yield by supporting three types of diagnostic methods for repair and diagnosis. The experiment results show that the proposed FPMBIST has small area overhead despite the fact that it supports various test algorithms, thus having high flexibility.

A Study on the Self-Diagnosis Criteria of Electrical Installations (자가용 전기설비의 자가진단 기준에 대한 연구)

  • Kim, Jong-Min;Lee, Hyeon-Woo;Kim, Hong-Ki;Yoo, Sang-Bong;Jang, Kyung-Bae
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.5
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    • pp.863-869
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    • 2017
  • This paper is to enable electrical safety manager to have more objective evaluation on the safety by indicating quantitative values such as life-time and status quotient of daily visual inspection on private electrical equipments. Self-diagnosis table is recommended to apply such a evaluation efficiently according to the characteristics of each electrical equipments, and the managers's determination of the precise inspection, replacement etc. will be also possible through the standard selected by various domestic and foreign data with expert's advise for numerical evaluation. This circumstance will be able to establish the foundation to secure the soundness of electrical equipments.

Development of Self-Diagnostic Smart Concrete (자가진단형 스마트 콘크리트 개발)

  • Kim Wha-Jung;Kim Ie-Sung
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2006.04a
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    • pp.82-88
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    • 2006
  • In People usually think that smart materials and smart structures have not been developed until recent years. But those kinds of sensors have already been used for sensing damage in a variety of materials and structures. Two typical examples are piezoelectric materials (e.g., PZT) and electric strain gauges. Load cell is an example that utilizes the piezoelectric property to measure the change in physical quantities occurred by applied loads, while strain gauges are used to measure the deformation of compressive and tension members. The feasibility of using smart materials is realized for a monitoring technology when those sensors are used to monitor damages at inside or outsider of the structures. In this study, a fundamental study on the development of self diagnostic smart concrete using PZT, and unsaturated polyester electric resistance sensor.

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