• 제목/요약/키워드: Self-Recovery

검색결과 401건 처리시간 0.031초

고체 전기활성 고분자 기반 가변 렌즈의 연구동향 (A Review: All Solid-state Electroactive Polymer-based Tunable Lens)

  • 신은재;고현우;김상연
    • 로봇학회논문지
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    • 제16권1호
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    • pp.41-48
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    • 2021
  • In this paper, we review papers which report to the all solid-state electroactive polymer-based tunable lens. Since electroactive polymer-based tunable lenses change their focal length by responding to electric stimuli, it can be minimized the size and weight of optical modules. Thus, it has been received attention in the robot, mobile device and display industry. The all solid-state electroactive polymer-based tunable lenses can be classified into two categories depending on the classification of materials: ionic electroactive polymer-based lenses and non-ionic electroactive polymer-based lenses. Most of the ionic electroactive polymer-based tunable lenses are fabricated with ionic polymer-metal composite. So, the ionic electroactive polymer-based tunable lenses can be operated under low electric voltage. But small force, slow recovery time and environmental limitation for operation has been pointed to the disadvantage of the lenses. The non-ionic electroactive polymer-based tunable lenses are classified again into two categories: dielectric polymer-based tunable lenses and polyvinylchloride gel-based tunable lenses. The advantage of the dielectric polymer-based tunable lenses is fast response to electric stimuli. But the essential flexible electrodes degrade performance of the lens. Polyvinylchloride gel-based tunable lens has reported impressive performance without flexible electrodes.

산후우울증과 관련된 질적 연구에 대한 보고 분석 (Report of the Qualitative Research Related to Postpartum Depression)

  • 박한송;이도은;윤인애;서효원;서주희
    • 대한한방부인과학회지
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    • 제34권1호
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    • pp.15-33
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    • 2021
  • Objectives: The purpose of this paper is to help the development of qualitative research in the field of Korean medicine and policy support for postpartum depression. Methods: Qualitative studies related to postpartum depression retrieved from five databases were evaluated independently by two researchers using the integrated criterion, Consolidated criteria for reporting qualitative research (COREQ). In addition, each subject of study was qualitatively synthesized. Results: A total of 1,374 papers were searched and 13 papers were finally selected. The results of the study using COREQ lacked information about the researchers. The results of the study were integrated into three themes: "Feeling Failure", "Struggling for self-identity and role of mother" and "Seeing Help and Recovery". Conclusions: Postpartum depression can be accessed through various methods such as Korean medicine counseling, acupuncture and herbal medicine, and further research and manual preparation is required.

Design and Implementation of Magnetic Stimulation Device Suitable for Herpes Zoster and Post Herpetic Neuralgia

  • Tack, Han-Ho;Kim, Gye-Sook;Kim, Whi-Young
    • 한국정보기술학회 영문논문지
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    • 제10권2호
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    • pp.199-214
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    • 2020
  • An important technique of the present invention is primarily to parallel light detection, self-pulse therapy after diagnosis. Herpes zoster is a disease caused by varicella zoster virus, and the virus that has been latent in the dorsal root ganglion that controls the skin segment loses its immune system and physically damages it. It is an acute skin disease in which acute pain and bullous rash occur along the sensory ganglia, which are rehab by inducers such as malignant tumors. Dorsal root ganglion after complete recovery of varicella, relapsed after incubation in brain ganglion, latent virus sometimes suppressed activity by cell mediated immunity, and in cell ganglion with reduced cellular immunity. It proliferates and destroys neurons, causing pain while forming a rash and blisters. This can reduce cell necrosis and increase the phagocytosis and enzymatic activity through the movement of ions through the cell membrane, depolarization and membrane potential change, growth factor secretion, calcium ion transfer, chondrocyte synthesis, etc., And may offer treatment options for lesions of herpes zoster and post-herpetic neuralgia (PHN).Therefore, according to the present research, the diagnosis and treatment device of treating paing for herpes zoster and post-herpetic pain can be implemented in the early stage of herpes zoster, and conventional analgesic regulation, anti-inflammatory effect, post-herpetic neuralgia.

Education Programs for Disaster Mental Health: Website-Based Review

  • Hyun-Seo Park;Joohee Seo;Sang-Ho Kim
    • 동의신경정신과학회지
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    • 제34권1호
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    • pp.43-59
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    • 2023
  • Objectives: Although a manual for a disaster medical support using Korean medicine doctors for disaster survivors has been developed, education programs for using the manual in disaster situations need to be developed. Thus, the purpose of this study was to analyze existing online education programs for disaster mental health to develop education programs for Korean medicine doctors. Methods: We conducted website searching for disaster mental health education programs using Google. Compositions, contents, hours, methods, costs, organizers, and targets of included educational programs were analyzed qualitatively. Results: After searching, eight websites among a total of 64 were included for the analysis. Lectures consisted of Psychological First Aid, Skills for Psychological Recovery, Self-Care, and Psychological Education after a disaster experience. Training hours for each program ranged from 30 minutes to 31 hours. All lectures were given only online. They could only be taken online. Free lectures were the most common ones. Most of them were for the general public. Conclusions: Findings of this study provide information regarding trends of online education programs for disaster mental health. Our information could be used for developing disaster trauma response education programs for Korean medicine doctors in the future.

Distinctive contribution of two additional residues in protein aggregation of Aβ42 and Aβ40 isoforms

  • Dongjoon Im;Tae Su Choi
    • BMB Reports
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    • 제57권6호
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    • pp.263-272
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    • 2024
  • Amyloid-β (Aβ) is one of the amyloidogenic intrinsically disordered proteins (IDPs) that self-assemble to protein aggregates, incurring cell malfunction and cytotoxicity. While Aβ has been known to regulate multiple physiological functions, such as enhancing synaptic functions, aiding in the recovery of the blood-brain barrier/brain injury, and exhibiting tumor suppression/antimicrobial activities, the hydrophobicity of the primary structure promotes pathological aggregations that are closely associated with the onset of Alzheimer's disease (AD). Aβ proteins consist of multiple isoforms with 37-43 amino acid residues that are produced by the cleavage of amyloid-β precursor protein (APP). The hydrolytic products of APP are secreted to the extracellular regions of neuronal cells. Aβ 1-42 (Aβ42) and Aβ 1-40 (Aβ40) are dominant isoforms whose significance in AD pathogenesis has been highlighted in numerous studies to understand the molecular mechanism and develop AD diagnosis and therapeutic strategies. In this review, we focus on the differences between Aβ42 and Aβ40 in the molecular mechanism of amyloid aggregations mediated by the two additional residues (Ile41 and Ala42) of Aβ42. The current comprehension of Aβ42 and Aβ40 in AD progression is outlined, together with the structural features of Aβ42/Aβ40 amyloid fibrils, and the aggregation mechanisms of Aβ42/Aβ40. Furthermore, the impact of the heterogeneous distribution of Aβ isoforms during amyloid aggregations is discussed in the system mimicking the coexistence of Aβ42 and Aβ40 in human cerebrospinal fluid (CSF) and plasma.

Recent Advances in Cell Therapeutics for Systemic Autoimmune Diseases

  • Youngjae Park;Seung-Ki Kwok
    • IMMUNE NETWORK
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    • 제22권1호
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    • pp.10.1-10.17
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    • 2022
  • Systemic autoimmune diseases arise from loss of self-tolerance and immune homeostasis between effector and regulator functions. There are many therapeutic modalities for autoimmune diseases ranging from conventional disease-modifying anti-rheumatic drugs and immunosuppressants exerting nonspecific immune suppression to targeted agents including biologic agents and small molecule inhibitors aiming at specific cytokines and intracellular signal pathways. However, such current therapeutic strategies can rarely induce recovery of immune tolerance in autoimmune disease patients. To overcome limitations of conventional treatment modalities, novel approaches using specific cell populations with immune-regulatory properties have been attempted to attenuate autoimmunity. Recently progressed biotechnologies enable sufficient in vitro expansion and proper manipulation of such 'tolerogenic' cell populations to be considered for clinical application. We introduce 3 representative cell types with immunosuppressive features, including mesenchymal stromal cells, Tregs, and myeloid-derived suppressor cells. Their cellular definitions, characteristics, mechanisms of immune regulation, and recent data about preclinical and clinical studies in systemic autoimmune diseases are reviewed here. Challenges and limitations of each cell therapy are also addressed.

야간 이갈이와 교근비대 환자의 보툴리눔 독소 주사 효과 (Nocturnal Bruxism and Botulinum Toxin Effect on the Subjects with Masseteric Hypertrophy)

  • 손승만;정기정;김미은;김기석
    • Journal of Oral Medicine and Pain
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    • 제32권3호
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    • pp.337-346
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    • 2007
  • 본 연구는 교근비대의 중요한 기여요인으로 간주되는 이갈이의 영향을 평가하기 위해 이갈이 습관의 유무에 따른 BTX-A 주사후의 임상적 변화를 조사하였다. 실험을 위해 양측성 교근비대를 가진 지원자 중, 야간 이갈이 습관을 가지고 있는 지원자 5명과 이갈이 습관이 없는 지원자 5명을 선택하여 BTX-A(Allergen Inc., $Botox^{(R)}$)를 25 unit씩을 양측 교근에 각각 주사하였다. BTX-A의 교근주사 후에 나타나는 변화를 평가하기 위하여 주사 전과 주사 후 2주, 4주, 8주, 3개월, 6개월 9개월에 각각 검사를 시행하여 초음파를 이용한 전측두근과 교근의 두께 측정, 전치부와 구치부의 최대교합력 측정, 교합력의 변화에 대한 주관적 평가를 비교하였다. 교근에 BTX-A를 주사한 후에 이갈이군과 비이갈이군 모두 초음파검사에서 교근의 두께가 감소되어 3개월 정도에 가장 현저한 위축 소견을 보였으며 이후 점차 회복되어가는 양상을 보였다(p<0.001). 비이갈이군과 비교하였을 때 이갈이군에서 교근두께의 회복이 더 현저하였으나, 주사 후 9개월에도 치료전과 비교했을 때는 여전히 근위축이 관찰되었다. 구치부 최대교합력도 교근두께 변화와 유사한 양상을 보였다. 전측두근과 전치부 최대 교합력은 주사 후 시간경과에 따른 변화를 보여 주지 않았다(p>0.05). 피검자가 스스로 느끼는 교합력은 주사 2주 후에 가장 저하되었다가 점차 빠르게 회복되어 6개월에서 9개월 사이 이전의 상태로 회복한 반면 교합력측 정기로 측정한 구치부 최대교합력의 상대적 변화는 최대교합력이 원래의 상태로 회복되지 못했음을 보여주었다. BTX-A 주사로 인한 상대적인 구치부 최대교합력의 저하는 비이갈이군에서 더욱 현저하게 관찰되었다. 이 실험의 결과는 이갈이는 BTX-A 주사 후에 발생한 교근 위축과 교합력 감소가 원상태로 회복되는 과정에 영향을 미칠 수 있음을 보여준다. 그러므로 이갈이 등의 이상기능 습관을 가진 교근비대 환자의 BTX-A 주사효과를 보다 오래 유지하기 위해서 주사와 함께 습관조절을 위한 교합장치의 사용을 고려할 필요가 있을 것으로 생각된다.

Suppression of Cocaine Intake by Acupuncture at HT7

  • Lee, Bong-Hyo;Kim, Sung-Hwan;Lim, Sung-Chul;Kim, Jae-Su;Lee, Yun-Kyu;Lee, Ji-Hye;Jung, Tae-Young;Yang, Chae-Ha;Yoon, Seong-Shoon;Han, Chang-Hyun;Lee, Kyung-Min
    • 대한한의학회지
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    • 제31권3호
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    • pp.17-27
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    • 2010
  • Objectives: Cocaine has been well known as a representative drug of abuse for its strong reinforcing effect linked to the mesolimbic reward system including dopamine, and such reinforcement leads to the addiction. Acupuncture has been used widely in eastern Asia for the treatment of various diseases including mental disorders and psychiatric problems, and is gathering more interest as one of the complementary and alternative medicines in western countries. In a previous study, we demonstrated that acupuncture at HT7 could affect dopamine release in the mesolimbic system of rats sensitized to alcohol and morphine. This study was designed to investigate whether acupuncture at HT7 could attenuate cocaine intake or not. Material & Methods: Male Sprague-Dawley rats weighing 270-300 g at the start of experiment were trained to self-administer food pellets under a fixed ratio 1 schedule. After the success of acquisition of 100 pellets within 3 h for 3 consecutive days, animals were subjected to surgery whereby Silastic tubing was implanted into right jugular vein and secured with mesh under the anesthetization using pentobarbital injection (50 mg/kg, i.p.). Following recovery, rats were trained to self-administer cocaine (0.25 mg/kg) in daily 2 h sessions under fixed ratio 1 schedule over 10 days. Each treatment was performed on the next day of each establishment of baseline. Results: Results show that acupuncture at HT7, but not at control points, reduced cocaine intake significantly. Acupuncture at HT7 decreased selectively active lever response from $63.15{\pm}3.35$ to $51.46{\pm}3.99$ corresponding $82.12{\pm}5.31%$ compared to basal level. Also, it was demonstrated that the effect of acupuncture was mainly occurred at the half period. Nevertheless, acupuncture at HT7 did not influence the food taking behavior. Conclusions: From the results of this study, it may be suggested that acupuncture at HT7, at least in part, could contribute to the treatment of cocaine abuse.

노인 뇌졸중 환자의 후유증 유무에 따른 HRQOL 요인별 중요도 분석 (A Study on Health Status' Factors Affecting HRQOL in the Elderly Stroke Patients With or Without Sequela)

  • 김석범;김동현
    • 대한지역사회작업치료학회지
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    • 제7권1호
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    • pp.37-47
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    • 2017
  • 목적 : 본 연구는 치료를 받고 있는 뇌졸중 환자 중 후유증의 유무에 따라 건강관련 삶의질(HRQOL)에 영향을 주는 건강상태의 중요도가 어떻게 달라지는지를 조사하여, 건강 관련 삶의 질 향상 방안을 위한 기초자료로 활용하는데 있다. 연구방법 : 뇌졸중 환자의 후유증 유무에 따라 HRQOL에 영향을 미치는 요인들의 중요도를 분석하기 위하여 국민건강영양조사 제5기의 자료를 활용하여 65세 이상 치료를 받고 있는 뇌졸중 환자 91명을 대상으로 2차 분석을 실시하였다. 결과 : 첫째, 후유증이 있는 뇌졸중 환자의 경우 없는 그룹보다 HRQOL과 주관적 건강상태가 유의하게 낮았으며(p<0.05), 자살 생각이 있을 위험도는 3.64였다. 둘째, 전체 그룹의 경우 주관적(${\beta}=0.39$), 정신적(${\beta}=0.29$), 의학적(${\beta}=0.23$) 건강상태가, 후유증이 있는 그룹의 경우 정신적(${\beta}=0.45$), 주관적(${\beta}=0.36$) 건강상태가, 후유증이 없는 경우 의학적(${\beta}=0.45$), 기능적(${\beta}=0.32$), 정신적(${\beta}=0.25$) 건강상태 순으로 HRQOL에 크게 영향을 주는 요인으로 추출되었다(p<0.05). 결론 : 종합하면 재활치료에 있어 뇌졸중 환자의 HRQOL 향상을 위해서는 후유증이 중증일 경우는 정신적 건강상태에 영향을 미치는 우울과 자살에 대한 조기 발견 및 조기 중재가 중요하며, 후유증이 경증이거나 없는 경우에는 기능적 회복에 초점을 맞추어 진행해야 하고, 후유증 유무와 상관없이 자신의 현 상태를 긍정적으로 받아들일 수 있도록 지속적인 지지를 해준다면 뇌졸중 환자의 기능적 회복과 더불어 HRQOL을 더욱 향상시켜 최종적으로 뇌졸중 환자의 독립적 자립에 긍정적인 영향을 줄 수 있을 것으로 사료된다.

산욕초기 초산모의 간호목표달성방번 합의가 어머니 역할수행에 대한 자신감 및 만족도에 미치는 영향에 관한 실험적 연구 (An experimental study on the impact of an agreement on the means to achieve nursing goals in the early postpartum period of primiparous mothers and enhance their self-confidence and satisfaction in maternal role performance)

  • 이영은
    • 대한간호학회지
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    • 제22권1호
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    • pp.81-115
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    • 1992
  • The problem addressed by this study was to determine the effect of nurse - patient agreement on the means to achieve nursing goals in the early postpartum period of primiparous mothers. It was hypothesized that the experimental treatment would result in hegher self-confidence and satisfaction in maternal role performance. This purpose was to contribute to the planning of nursing care to enhance self- confidence and satisfaction in maternal role performance and to the development of relevant nursing theory. Especially, the early postpartum period is crucial toward in recovery from childbirth and attainment of the maternal role. Maternal role attaintment is a complex social and cognitive process of stimulus -response accomplished by learning. Most women attain the maternal role sucessfully. But, some primiparous mothers experience difficultites in attainment of the maternal role due to lack of experience and knowledge. Self-confidence and satisfaction in maternal role performance are important factors in attainment and adjustment to the maternal role (Mercer, 1981a, 1981b ; Lederman, Weigarten, and Lederman, 1981 :Bobak and Jensen, 1985). Nursing is defined as behaviors of nurses add patients that attain nursing goals through action, reaction, interaction, and transaction. For attainment of nursing goals, active participating transactions must occur by agreement on the means to achieve those goals through nurse -patient mutual goal setting and establishment of their active relationships(King, 1981, Ha, 1977). Based on King's theory of goal attainment (1981), this stuy was planned as a non-equivalent control group, non -synchronized quasi -experimental design using agreement on the means to achieve nursing goals in early postpartum as the experimental treatment. The data were collected from July 20 to Sep. 1, 1991 by questionnaires with 60 primiparous mothers planing to breast feed after normal deliveries at W hospital in Pusan, Korea. The subjects were divided into a control group(conventional group) -those admitted from July 20 to Aug. 12, and an experimental group(agreement group) - those admitted from Aug. 13 to Sep. 1. The instument for agreement on the means to nursing goals in the early postpartum period included five steps - identification of disturbances of problems through action, reaction, and interaction with primiparous mothers : mutual early postpartal nursing goal setting : exploration of the means to achieve goals ; agreement on the means (self- care, ealry maternal -infant contact, performance of mothering behavior, and communicating about the infant's behavior and health condition) : implementation of the means. This instrument was developed on the basis of King's elements that lead to transactions in nurse-patient interactions. Lederman et al's (1981) scale for Confidence in ability to cope with tasks of motherhood and Lederman et al's(1981) scale for Mother's satisfaction with motherhood and infant care were used to measure self-confidence and satisfaction in maternal role performance ·with the subjects immediately after admission and on the day of discharge. Self-care performance in the experimental group was measured by self -evaluation tool developed by the investigator from the literature concerned. The tools to measure Pelf-confidence and satisfaction in maternal role performance, and the tool to measure self-evaluation of self-care performance were tested for internal reliability. Cronbach's Alphas were 0.94, 0.94, and 0.63. The data were analysed by using in S.P.S.S. computerized program and included percentage, x²-test, t-test, ANOVA, and Pearson Correlation Coefficient. The conclusions obtained from this study are summerized as follows : 1. The degree of self-confidence in maternal role performance of the total subjects group measured before the experimental treatment was above average with a mean score of 2.77(range 2.14-3.64). Out of 14 items, those with relatively high mean scores were ‘I would like to be a better mother than I am’(3.95), and ‘I have my doubts about whether I am a good mother’(2.87). Those with low mean scores were ‘I know that my baby wants most of the times’(2.28), ‘When the baby cries, I can tell what she /he wants’(2.37), and ‘I have confidence in my ability to care for the baby’(2;50). That is, the self - confidence of Primiparous mothers was considerably high in mothering, but rather low in activities concerning the infant care and understanding of the infant behavior. The degree of satisfaction in maternal role performance of the total subjects group measured before the experimental treatment was high with a mean score of 3.18(range 1.92-3.92). Out of 13 items, those with relatively high mean scores were ‘I am glad 1 had this baby now’(3.75), ‘I play with the baby between feedings when s/he is awake and quiet’(3.67), and ‘I enjoy being a mother’(3.27). Those with low mean scores were ‘I am upset about having too many responsibilities as a mother’(2.78), ‘It bothers me to get up for the baby at night’(2.82), and ‘I get annoyed if the baby frequently interrupts my activities’.(2.82), That is, the satisfaction of primiparous mothers was considerably high in mothering and infant care, but rather low in restraints in time or on the mother's self accomplishment and development. 2. Agreement on the means to achieve nursing goals in the early postpartum period included process of mutual goal setting, exploration of the means to achieve goals, and ahreement in concert means to achieve goals based on the mothers' condition, concerns, self-perception of the nurse - patient interactions. In the process of agreement, there was agreement that the means to achieve goals should be through trust and establishment of active relationships with the nurse through identification of problems according to planned nursing goals and active interaction, such as explanations, teaching, changing of opinions, acceptance or rejection of explanations, and proposing of questions. Therefore agreement on the means to achieve nursing goals in the early postpartum period appears to be an effective nursing intervention for primiparous mothers. 3. The degree of self- confidence in maternal role performance of the exprimental group was higher than that of the control group(t=3.95, p<0.01). Out of 14 items, those with higher score in the experimental group were ‘I would like to be a better mother than I am’(t=1.93, p<0.05), ‘I know that my baby wants most of the times’(t=2.75, p<0.01), ‘When the baby cries, 1 can tell what she/he wants’(t=2.10, p<0.05), ‘I have confidence in my ability to care for the baby’(t=3.72, p<0.01), ‘I trust my own judement in deciding how to care for the baby’(t=1.96, p<0.05), ‘I feel that I know my baby and what to do for him /her’(t=2.44, p<0.01), ‘I am concerned about being able to meet the baby's needs’(t=2.87, p<0.01), ‘I know what my baby likes and dislikes’(t=3.26, p<0.01), ‘I don't know to care for the baby as well as I should’(t=2.07, p<0.05), and ‘I am unsure about whether I give enough attention to the baby’(t=3.04, p<0.01), That is, the degree of self-confidence in mothering, activities concerning infant care, and understanding of infant behavior of the experimental group was higher than that of the control group. Therefore, the first hypothesis, that the degree of self-confidence in maternal role performance of the experimental group would be higher than that of the control group, was supported(t=3.95, p<0.01). 4. The degree of satisfaction in the maternal role performance of the exprimental group was higer than that or the control group(t=2.31, p<0.05). Out of 13 items, those with higher score in the experimental group were ‘I am glad I had this baby now’(t=2.29, p<0.05), ‘I enjoy taking care of the baby’(t=2.4g, p<0.01), ‘It is boring for me to care for the baby and do the same thing over and over’(t=2.87, P<0.01), ‘I am unhappy with the amount of time I have for activities other than childcare’(t=2.51, p<0.01), and ‘When bathing and diapering the baby, I would like to be doing something else’(t=2.43, p<0.01). That is, the degree of satisfaction in mothering, infant care, and restraints in time of on the mother's self accomplishment and development in the experimental group was higher than that of the control group. Therefore, the second hypothesis, that the degree of satisfaction in maternal role performance of the experimental group would be higher than that of the control group, was supported(t=2.31, p<0.05). 5. The third hypothesis, that the higher the degree of satisfaction in materenal role performance, the higher the degree of self-confidence in materenal role performance in the experimental group, was supported (r=0.57, p<0.01)

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