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HEALTH RISKS POSED BY MYCOTOXINS IN FOODS

  • Hsieh, D.P.H.
    • Toxicological Research
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    • v.6 no.2
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    • pp.159-166
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    • 1990
  • The ability of many toxigenic fungi to invade and develop in a wide variety of raw ingredients of human diet renders human exposure to mycotoxing very difficult to avoid. Most of the energy-rich commodities, such as cereal grains, oil seeds, tree nuts, and dehydrated fruits, are susceptible to mycotoxin contamination. Mycotoxins therefare have been recognized as an important class of hazardous substances in the human food chain. Although human exposure to mycotoxins is largely through ingestion, inhalation and skin contact may also be significant under conditions other than consumption of foods. Human ingestion of mycotoxins is due to consumption of contaminated dietary ingredients and the edible tissues and products of domestic animals that have been exposed to mycotoxins in moldy feed. Large scale acute human mycotoxicoses, such as ergotism in France, alimentary toxic aleukia in Russia, yellow rice syndrome in Japan, endemic nephropathy in Balkan countries, and acute aflatoxin poisonings in India and Taiwan, have been well documented, indicating that mycotoxicosis is a global problem. In some incidents, hundreds of victims were killed and many more became seriously ill. The mycotoxins that have been implicated in the etiology of these human diseases include aflatoxins, citreoviridin, cyclopiazonic acid, ergot alkaloids, moniliformin, ochratoxin A, trichothecenes, tenuazonic acid, and zearalenone. Among these, aflatoxins have been also implicated in the etiology of human primary liver cancer in those high-incidence countries in Africa and southeast Asia. It is well recognized that cause-effect relationship between mycotoxins and human diseases is very difficult to establish, especially for the cancer connection. Careful risk assessment must be performed to determine whether a mycotoxin indeed warrants costly regulatory actions.

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Establishment of Sesame Cultivation Practices as Succeeding Cropping System of Watermelon in the Greenhouse Condition

  • Shim, Kang-Bo;Hwang, Jung-Dong;Pae, Suk-Bok;Lee, Myoung-Hee;Ha, Tae-Joung;Park, Chang-Hwan;Park, Keum-Yong;Son, Jeong-Hee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.55 no.3
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    • pp.195-199
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    • 2010
  • This experiment was conducted to develop optimum sesame cultivation practices as succeeding cropping system of watermelon in the greenhouse condition. We also compared major components in sesame seed cultivated in the greenhouse and open field condition. The adaptable varieties under the greenhouse condition were white sesame 'Pyoungan' and black sesame 'Jinki' which showed higher yield and disease resistance. We also conducted several experiments to determine optimum sowing date, planting density and pinching time. Grain yields were statistically different according to the several sowing dates. In general, sesame sowing on June 30th showed higher grain yields than July 10th, July 20th and July 30th in the greenhouse. We also found out sesame cultivation practice with the row spacing of 40 cm and interplant spacing of 30 cm (a few branch type) or 40 cm (many branch type) showed higher yield than other treatments. Optimum pinching time was 25 days after first flowering in main stem when thousand seed weight and grain yield were highest. In the comparison of major components of sesame at the different cultivation conditions, sesame seeds cultivated in the greenhouse contained 4% much more oil content than open field condition. The lignan compounds, sesamin and sesamolin were also higher by 6% in the greenhouse than open field condition. It was concluded that sesame cultivation practices as succeeding cropping system of watermelon in the greenhouse condition guaranteed higher grain yield with less labor input which is now emerging alternative farming practice system in present aging rural society and will also give sesame cultivation farmers to increase net income in Korea.

Change in Sterol Compositions of Sesame Seed during Storage (저장중 참깨의 스테롤 조성변화)

  • Choi, Sang-Do;Yang, Min-Suk
    • Korean Journal of Food Science and Technology
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    • v.17 no.6
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    • pp.431-436
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    • 1985
  • The major sterol in the unsaponifiable matter (15.9 mg per gram on basis) of the sesame oil was 4-desmethylsterol (55.6%). 4-desmethylsterol consists of sitosterol (29.5%), campesterol (9.8%), ${\Delta}^5$-avenasterol (6.6%) and stigmasterol (5.9%). Between the packing bags kept the sesame seeds in, namly, the cotton and polyethylene bag, the campesterol content of sesame stored in the cotton bag was not nearly changed, whereas stored in the polyethylene bag was increased upto 4 months storage and then decreased until 15 months. The sitosterol content of sesame stored in cotton bag was increased upto 4 months and then decreased sharply until 15 months of storage, whereas stored in the polyethlene bag was not changed upto 4 months and slightly increased upto 9 months and again decreased until 15 months. Between the storage conditions, namly, light and dark storage, the stigmasterol content of the sesame stored under light condition was hardly changed upto 9 months and slightly increased after that, whereas stored under dark condition was increased upto 4 months, decreased upto 9 months and again slightly increased after that. ${\Delta}^5$-avenasterol was not much changed in all the storage conditions.

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Current Achievement and Perspectives of Seed Quality Evaluation in Soybean (콩 품질평가 현황과 전망)

  • 김용호
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.47
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    • pp.95-106
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    • 2002
  • Soybean is one of the most important sources of protein and oil in the world. Recently, emphasis has been laid on the chemical composition of soybean seeds for the processing soybean foods. Improvement of soybean components has been expected to improve food-processing quality for the processed soybean products such as soymilk and various edible ingredients as well as fur the traditional soyfoods. In Korea, soybean breeding research programmes have been focused on the quality of the products derived from soybean with yield stability, and some new modified soybean varieties haying good food-processing quality were developed recently. So the efforts of establishing standard and standardization of products in soybean are important. Three main categories should be considered in view of soybean seed quality; the marketing value such as grain size, shape, and appearance; the eating and processing value such as dehulled ratio, water absorption rate, and benny flavor; the nutritional value such as protein, lipid, and carbohydrate contents. And the new frontiers in research are looking at the functional nutrients in soybeans and how to improve them. In case marketing value, mainly the appearance is evaluated, therefore, each country has an application of standard related to quality. Each determination of standard class, heat-damaged kernels, splits, and soybeans of other colors is made on the basis of the grain when free from foreign materials. But processing value and nutritional value for standardization were not studied in detail till now. In addition, soybean has potential roles in the prevention and treatment of chronic diseases, most notably cancer, osteoporosis, and heart disease. The functional nutrients include a protease inhibitor, phytic acid, saponins, and isoflavones, etc.. It is believed that standardization of soybean quality should perform to overcome the difficulties, relatively high price of domestic soybean products has weakened the competitive power, in the market related to WTO. So, we should focus on further research into the evaluation and establishment of quality-standard in soybean.

Review on Clinical Trials of Black Seed (Nigella sativa) and Its Active Constituent, Thymoquinone

  • Tavakkoli, Alireza;Mahdian, Vahid;Razavi, Bibi Marjan;Hosseinzadeh, Hossein
    • Journal of Pharmacopuncture
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    • v.20 no.3
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    • pp.179-193
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    • 2017
  • Objectives: Nigella sativa (black seed or black cumin), which belongs to the Ranunculacea family, is an annual herb with many pharmacological properties. Among its many active constituents, thymoquinone (TQ) is the most abundant constituent of the volatile oil of Nigella sativa (N. sativa) seeds, and it is the constituent to which most properties of this herb are attributed. Methods: PubMed-Medline, Scopus, and Web of Science databases were searched to identify randomized control trials (RCTs) investigating the therapeutic effects of N. sativa and/or TQ. In this review, we investigated the clinical uses of N. sativa and TQ in the prevention and the treatment of different diseases and morbidity conditions in humans. Results: Black seed and TQ are shown to possess multiple useful effects for the treatment of patients with several diseases, such as inflammatory and auto-immune disorders, as well as metabolic syndrome. Also, other advantages, including antimicrobial, anti-nociceptive and anti-epileptic properties, have been documented. The side effects of this herbal medicine appear not to be serious, so it can be applied in clinical trials because of its many advantages. Conclusion: Some effects of N. sativa, such as its hypoglycemic, hypolipidemic and bronchodilatory effects, have been sufficiently studied and are sufficiently understood to allow for the next phase of clinical trials or drug developments. However, most of its other effects and applications require further clinical and animal studies.

A study on the impact load acting on an FPSO bow by steep waves

  • Hong, Sam-Kwon;Lew, Jae-Moon;Jung, Dong-Woo;Kim, Hee-Taek;Lee, Dong-Yeon;Seo, Jong-Soo
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.9 no.1
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    • pp.1-10
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    • 2017
  • Various offshore structures such as FPSO, FSO, Semi-submersible, TLP and Spar are operated to develop offshore oil and gas fields. Most of the offshore structures shall be operated over 20 years under the harsh environments at sites so that the offshore structures should be designed to endure the harsh environments. In this study, the effect of the impact load (so called slapping load) by the steep waves acting on the FPSO bow is investigated through the model test. For measurement of the impact pressures on the frontal area, a bow-shaped panel was fabricated, and installed the pressure sensors on the bow starboard side of the model FPSO. During the model test campaign, the impact load was investigated using the steep waves with $Hs/{\lambda}$ greater than 1/16 of the representative wave condition. Consequently, it is confirmed through the model test that the impact loads acting on the FPSO bow are significantly increased with the steep waves ($Hs/{\lambda}$ > 1/16) than the representative wave conditions of a maximum significant wave height and a pitch forcing period. Therefore, for safe design of North Sea FPSO, it is necessary to consider the steep waves in addition to the representative wave conditions and to be applied as proper structural load. Also, the effect of random seeds in irregular waves should be considered to build the safe FPSO.

Yield Performance and Nutritional Quality of 'Agakong' Soybean Harvested in Drained-Paddy and Upland Fields

  • Eun, Jhong-Ho;Rico, Cyren M.;Kim, Man-Keun;Souvandouane, Souliya;Son, Tae-Kwon;Shin, Dong-Il;Chung, Il-Kyung;Lee, Sang-Chul
    • Korean Journal of Plant Resources
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    • v.20 no.3
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    • pp.258-262
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    • 2007
  • The study was conducted to evaluate the performance of the popular isoflavone-rich soybean 'agakong' in upland and in drained-paddy fields. Analysis revealed no significant variation in terms of plant height, number of seeds per pod, number of nodes, and 100-seed weight between the two cropping system. Number of pods was significantly higher in paddy field(234.2kg 10a$^{-1}$) compared to those harvested in the upland field, which was later manifested on the yield where paddy soybeans obtained 278.1kg 10a$^{-1}$ whereas upland only obtained 179.3kg 10a$^{-1}$. This observed difference in yield was attributed to the observed higher amount of N in the paddy soil (0.907%) as compared to the upland soil (0.458%). In terms of nutritional content, protein and phytic acid contents were the only parameters that showed significant differences while oil, sugar, reducing power and fatty acids were all comparable in paddy and filed condition. Protein content was higher in upland soil (47.4%) than that of the paddy (44.9%) soil. On the opposite, phytic acid was higher in paddy (2.90%) than in upland (1.09%). This study showed that the yield of soybean is generally a factor of soil N, drained-paddy field production of soybean is comparable to upland-filed production with the benefit of increasing phytic acid content while maintaining its nutritional value.

The bibliographical Study on the Famine Relief Food of Chosun-dynasty (조선시대 구망식품의 문헌적 고찰)

  • 김성미;이성우
    • Journal of the East Asian Society of Dietary Life
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    • v.2 no.1
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    • pp.35-56
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    • 1992
  • This paper has made a close examination of Shingan Goohwang Chowalyo(1660), Cheesaeng yoram(1691), Sallim Gyungjae(1715) and Imwon simyook Jee(1827), to grasp what kinds of famine relief foods have been analyzed in terms of nutrition elements and cooking methods. And also this paper has surveyed the changes of these famine relief foods according to the times. Three hundred forty one famine relief foods are recorded in the above mentioned books, Among them, ten foods are recorded in common in these four books: pine needles, elm tree skin, soybeans, wax, jujubes, black beans, glutinous millet, turnip seeds white pine-mushroons and Chool-Atractylodes japonica. The methods of cooking and processing are most varied in the order of pine needles, black beans and elm tree skin, Pine needles are rich in protein and fat, and so may be regarded as the first of famine relief foods. Elm tree skin is of more than 50% carbohydrate and may be used in plate of cereals. I addition to these, Hwangui-milk vetch, Choonsu-cedrela Sinensis, Tacksa-Alisma Orientale Juzep and some other foods contain starch, glucose, fatty acids, and amino acids. So they may be used for replacing cereals and relieving famine. Before these famine relief foods are cooked or processed, according to their ingredients they should be soaked in water for a time in some cases the water should be changed several times. In Shingan Goohwang Chowalyo and Cheesaeng Yoram, measuring units are rarely recorded, while in sallim Gyungjae, they are explicitly shown. Imwon Simyook Jee clearly shows the use of oriental medicine materials. And the fur above mentioned books show no record of famine relief animal foods. To these days, vegetables have been boiled, squeezed and seasoned with salt and oil, but the better the economic conditions become, the less other famine relief foods are used. Nevertheless it is expected that these natural foods can be made favorite dishes with the best use of their good flavors and tastes.

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Radio-sensitivity Analysis and Selection of Useful Mutants of Rape (Brassica napus L.) by Gamma Irradiation (방사선 처리에 의한 유채의 생육 및 감수성 조사)

  • Goh, Eun Jeong;Kim, Wook-Jin;Kim, Jin-Baek;Kim, Dong Sub;Kim, Sang Hoon;Kang, Si-Yong
    • Journal of Radiation Industry
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    • v.4 no.3
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    • pp.277-283
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    • 2010
  • Rape (Brassica napus L.) plants are one of the major oilseed crops. The main components of rapeseed are oil (35 to 47%) and protein (15 to 32%). For the biodiesel production, the development of a new variety of rape plant with high biomass and/or oleic acid contents is required. In order to determine the optimum dose of gamma-ray irradiation, the rape seeds of cvs. Hanra (Hr), Youngsan (Ys), Tammi (Tm), and Tamra (Tr) were irradiated with a 100~4,000 Gy dose range of gamma-rays. Considering the growth factors, the optimum doses were determined to be within the range of 600~1,000 Gy for the selection of useful mutant lines. Six-hundred and eighty-eight (688) $M_2$ mutant lines were obtained from 600~1,000 Gy gamma-ray-irradiated $M_1$ plants through selfing. The growth characteristics, leaf shape, early flowering, and flower color were all investigated. The selected mutant numbers of early flowering, leaf shape, and flower color were 34, 52, and 3 from the four cultivars, respectively. These mutant lines will be used for the development of a new variety of rape plant with high biomass and oleic acid contents.

Variation of Caffeic acid, Rosmarinic acid, Luteolin and Apigenin Contents in Perilla Germplasm

  • Lee, Myoung-Hee;Jung, Chan-Sik;Pae, Suk-Bok;Hwang, Chung-Dong;Park, Chang-Hwan;Shim, Kang-Bo;Park, Keum-Yong;Kim, Hyun-Kyung;Park, Soon-Ki;Ha, Tae-Joung
    • Korean Journal of Breeding Science
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    • v.41 no.4
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    • pp.391-396
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    • 2009
  • Perilla frutescens, which belonging to the Labiatae family, is widely cultivated oil crop and have been used traditional herbal medicine in East Asia such as Korea, China, and Japan. Especially, the leaves and the seeds of this species are important in Korean traditional cooking, as one of the popular garnish and food colorants. Numerous studies have revealed that the beneficial health effects of perilla are due to its several phytochemicals contents, such as rosmarinic acid, caffeic acid, luteolin, and apigenin. For this reason, increasing the content of phytochemicals in perilla hasbecome a major breeding objective. The genetic diversity of the rosmarinic acid, caffeic acid, luteolin, and apigenin content in perilla seed is poorly documented. We analyzed the rosmarinic acid, caffeic acid, luteolin, and apigenin content of 203 accessions of perilla germplasm by high performance liquid chromatography (HPLC). The rosmarinic acid and luteolin contents ofgermplasms were ranged from $15.7{\mu}g/g$ to $2717.1{\mu}g/g$ and from $1.6{\mu}g/g$ to $582.4{\mu}g/g$ respectively.