• 대한기계학회논문집
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• 제6권4호
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• pp.331-340
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• 1982

Numerical analysis is made on the turbulent heat transfer with suspension of solid particles in circular tube with constant heat flux. The mean motion of suspending particles in mixture is treated as the secondary gas flow with virtual density and viscosity. Our modeling of turbulent transport phenomena of suspension flow is based on this assumption and conventional mixing length theory. This paper gives the evidence that the mixing length models can be extended to close the governing equations for two phase turbulent flow with solid boundary at a first order level. Results on Nusselt numbers obtained by analytical treatments are compared with available experimental data and discussed. They suggest that the most important parameters of two phase turbulent heat transfer phenomena are relative particle diameter to pipe diameter, gas-solid loading ratio, and specific heat of suspending material.

• 한국철도학회논문집
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• 제5권1호
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• pp.40-47
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• 2002

In this study, and analytical method for ride sensitivity analysis of a train with non-linear suspension elements are proposed. Non-linear characteristics of springs and dampers for primary and secondary suspensions of a train are parameterized using polynomial interpolation. Vertical dynamic model of a three-body train running on straight rail with the predetermined roughness expressed in terms of spectral density function is set up and its equations of motion for ride analysis are derived. Using the direct differentiation method, sensitivity equations of the vertical dynamic model with respect to design parameters associated with non-linearity of suspensions are obtained. Based on the sensitivity analysis, improvement of ride is achieved by varying appropriate suspension parameters.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.1578-1583
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• 2007

The suspension system of railway rolling-stock is composed of the primary and secondary suspension elements. Recently, a conical rubber spring is widely used as the primary suspension element due to the merits of the three directional stiffness characteristics. So, understanding the properties and characteristics of the conical rubber spring is very important from the viewpoint of vehicle stability and efficient maintenance. Thus, this study is started to acquire the basic data for maintaining spring elements efficiently. For this, we tested the conical rubber spring samples including a new and old specimen with aging. As a test result, we have obtained the property characteristics of the aged spring comparing with the new product and we describe the results.

• 한국약용작물학회지
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• 제20권6호
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• pp.479-486
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• 2012

The production of adventitious roots derived from root explant of Echinacea angustifolia and its secondary metabolite content were assessed in different types and levels of auxin. The induction of adventitious roots from root explant cultured in Murashige and Skoog solid medium supplemented with 1.0 mg/L indole -3-butyric acid (IBA) attained highest as 20.87 mg fresh weight and 3.07 mg dry weight per culture but root suspension culture at the same concentration of IBA enhanced biomass production as 3.07 g fresh weight and 0.38 g per culture after 4 weeks in culture. 3.0 mg/L ${\alpha}$-naphthalene acetic acid (NAA) treatment had similar effect on root biomass production as 3.07 g fresh weight and 0.38 g per culture with liquid suspension culture, whereas adventitious roots exposed to over 3.0-5.0 mg/L IBA or 5.0 mg/L NAA were less responsive by reducing the number of adventitious roots and/or changing root morphology such as short and thick. The content of secondary metabolites such as phenolic, flavonoids and total caffeic acid in adventitious roots cultured on MS medium supplemented with 1.0 mg/L IBA were attained highest as 27.20, 9.60. 10.67 mg/g dry weight, respectively. Overall, the best production of root biomass and secondary metabolites were given by 1.0 mg/L IBA.

• 한국식물학회:학술대회논문집
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• 한국식물학회 1995년도 식물학심포지움 식물로부터 유용 2차대사산물의 생산 PRODUCTION OF USEFUL SECONDARY METABOLITES FROM PLANTS
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• pp.40-56
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• 1995

During the past two decades, China has seen her great progress in plant biotechnology. Since the Chinese market of herb medicine is huge, while the plant resources are shrinking, particular emphasis has been placed in plant tissue and cell cultures of medicinal plants, this includes fast propagation, protoplast isolation and regeneration, cell suspension cultures and large scale fermentation. To optimize culture conditions for producing secondary compounds in vitro, various media, additives and elicitors have been tested. Successful examples of large scale culture for the secondary metabolite biosynthesis are quite limited : Lithospermum ery throrhizon and Arnebia euchroma for shikonin derivatives, Panax ginseng, P. notoginseng, P. quinquefolium for saponins, and a few other medicinal plants. Recent development of genetic transformation systems of plant cells offered a new approach to in vitro production of secondary compounds. Hairy root induction and cultures, by using Ri-plasmid, have been reported from a number of medicinal plant species, such as Artemisia annua that produces little artemisinin in normal cultured cells, and from Glycyrrhiza uralensis. In the coming five years, Chinese scientists will continue their work on large scale cell cultures of a few of selected plant species, including Taxus spp. and A. annua, for the production of secondary metabolites with medicinal interests, one or two groups of scientists will be engaged in molecular cloning of the key enzymes in plant secondary metabolism.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권2호
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• pp.162-166
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• 2001

Obstructive sleep apnea syndrome(OSAS) is a complex sleep disorder characterized by intermittent apnea secondary to sleep-induced obstruction of the upper airway. It occurs because of an airway obstruction anywhere between the trachea and the oronasal apparatus. The hallmark of OSAS is snoring, which is caused by vibration of the tissues of the pharynx as the airway narrows. The consequences of OSAS have focused on excessive daytime sleepiness resulting from sleep fragmentation and the cardiovascular derangements producing hypertension and arrhythmias. The primary method of controlling OSAS has been surgery. The current surgical procedures used for OSAS are tracheostomy, tonsillectomy, nasal septoplasty, uvulopalatopharyngoplasty, anterior mandibular osteotomy with hyoid myotomy and suspension, and maxillary, mandibular and hyoid advancement. We report a case of OSAS that was improved by genial advancement with infrahyoid myotomy and suspension. The patient was objectively documented by polysomnography, cephalometric analysis, and physical examination before the surgical procedure. The patient underwent genial advancement with infrahyoid myotomy and suspension. Patient had a good response from surgery.

• 한국약용작물학회지
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• 제14권4호
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• pp.255-260
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• 2006

본 연구를 통해 헛개나무의 기내유묘의 조직절편으로부터 배발생캘러스의 유기 및 2차 배형성, 그리고 배발생캘러스의 현탁배양계로부터 체세포배를 대량생산하여 식물체로 재분화시키는 시스템을 확립하였다. 현탁배양을 통해 배발생세포의 유도 및 증식에는 모두 $30^{\circ}C$의 고온이 효과적이었는데 이와 같은 온도조건에서 배발생캘러스 유도율과 배발생캘러스의 생장량은 각각 100%와 894.6 mg로 $25^{\circ}C$에 비해 1.53배와 9.19배로 높게 나타났다. 배발생세포를 $18^{\circ}C$에서 배양할 경우 체세포배로 전환되었고 배양 5주후 체세포배로 발달하였으며 $25^{\circ}C$ 이상의 배양온도에서는 배발생세포는 증식만 할뿐 체세포배는 형성되지 않았다. 체세포배로부터 식물체의 형성은 $18^{\circ}C$ 저온에서만 가능하였다. 배지에 0.1과 0.5 mg/l BA를 첨가할 경우 식물체 재분화율은 37%와 28%로 생장조절물질을 처리하지 않은 배지에 비해 2.2배와 1.7배로 높게 나타났다 재분화된 식물체의 성장에 주는 무기염의 영향을 조사하기 위하여 유식물체를 MS와 1/3MS 고체배지에 옮겨 배양한 결과 1/3MS배지가 줄기신장과 뿌리의 유도에 적합하였다.

• 한국정밀공학회지
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• 제31권9호
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• pp.765-771
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• 2014

During the acceptance test of KTX, unexpectedly great lateral vibration in 14th~16th train at 150km/h~200km/h was appeared on a straight line in the winter season. Generally, stiffness of secondary suspension in KTX vehicle is one of the most sensitive components on air temperature. So, we examined that the secondary suspension to be mounted heating system was able to reduce the lateral vibration in the tail car of KTX. Also, we verified that lateral vibration from test results on KTX train with wheel conicity 1/20 disappeared. In this paper, we analysis effective reduction methods and the cause of the lateral vibration using model of KTX train and compare with the test results. The analysis results agree well with test ones. From mode analysis result, lateral vibration is occurred at natural frequency range 0.5~0.6Hz with a negative damping value and its natural frequency disappear gradually according to increasing of wheel concinicy.

• Biotechnology and Bioprocess Engineering:BBE
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• 제7권3호
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• pp.138-149
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• 2002

Plant cell culture provides a viable alternative over whole plant cultivation for the production of secondary metabolites. In order to successfully cultivate the plant cells at large scale, several engineering parameters such as, cell aggregation, mixing, aeration, and shear sensitivity are taken into account for selection of a suitable bioreactor. The media ingredients, their concentrations and the environmental factors are optimized for maximal synthesis of a desired metabolite. Increased productivity in a bioreactor can be achieved by selection of a proper cultivation strategy (batch, fed-batch, two-stage etc.), feeding of metabolic precursors and extraction of intracellular metabolites. Proper understanding and rigorous analysis of these parameters would pave the way towards the successful commercialization of plant cell bioprocesses.

• Archives of Plastic Surgery
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• 제36권5호
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• pp.637-641
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• 2009

Purpose: Most unilateral secondary cleft lip nose deformities have depressed nostril base and sill on the cleft side. To obtain a symmetric nose, correction of the recession on nostril is critical. The authors have worked out effective methods to elevate the nostril of the cleft side according to the extent of the depression. Methods: A total of 115 unilateral secondary cleft lip nose deformity patients with nostril depression were evaluated. Data were acquired from patients' charts and photography with special reference to the height difference of the nostrils between the cleft side and the non - cleft side. Patients were divided into three groups based on the difference and operated with various techniques : (1) mild degree(< 1 mm) with graft, (2) moderate degree(1 ~ 3 mm) with C - flap or suspension suture of septal cartilage (3) severe degree(> 3 mm) with graft, C - flap and suspension suture. Follow - up period averaged 21.3 months. Results: Forty - six patients(40 percent) were in mild group, and forty - two(37 percent) were in moderate. In twenty - seven patients(23 percent), nostril recession was more than 3 mm. The elevated nostril base and sill were maintained without height alteration during follow - up. Conclusion: The symmetry of the nostril base, especially projection of nostril sill influences successful correction of unilateral cleft lip nose deformity. Our tolerable techniques can be applied to most deformities with nostril depression and can present a new guideline.