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Micelles in Physical Chemistry Laboratory. Surfactant Catalyzed Oxidation of Glycine by Acidic Permanganate

  • Pare, Brijesh;Kaur, Parwinder;Bhagwat, V.W.;Fogliani, Charles
    • Journal of the Korean Chemical Society
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    • v.48 no.2
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    • pp.195-202
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    • 2004
  • Micellar catalysis is an essential part of theoretical and experimental curricular. The sodium dodecylsulfate (SDS) catalyzed reaction between glycine and potassium permanganate in acidic medium is an ideal kinetic experiment for the secondary and undergraduate physical chemistry laboratory, to show the effect of micellar catalysis on rate of the reaction. The reaction is conducted both with and without SDS to observe the rate enhancement in the presence of surfactant. To show surfactant catalysis a plot between k and [SDS] is plotted. As surfactant catalysis is observed even before the critical micelle concentration of SDS, this pre-micellar catalysis can be understood in the light of positive co-operativity. The value of positive cooperative index (n) has been found to be 2.37. Further, dependence of the reaction rate on substrate and oxidant concentrations is also discussed. The reaction follows pseudo-first-order kinetics. The overall reaction is second order, with first-order dependence on both glycine and permanganate concentrations. The theory of surfactant catalysis is also discussed. With the conditions specified in the experiment, total reaction times are in 3~4 hours lab session, thus allowing several data sets to be acquired in a single laboratory period. Preparation of solutions and procedure is also given in detail.

Development of a Tool to Measure Suffering in Patients with Cancer (암환자의 고통 측정도구 개발에 관한 연구)

  • 강경아
    • Journal of Korean Academy of Nursing
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    • v.29 no.6
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    • pp.1365-1378
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    • 1999
  • This study is a methodological research study to develop an instrument to measure in patients with cancer and to test the validity and reliability of the instrument. The research procedure was as follows : 1) The first step was to develop conceptual framework based on a comprehensive review of the literature and in-depth interviews with patients with cancer. This conceptual framework was organized in to three dimensions (the intrapersonal dimension, the significant-other and context related dimension, the transcendental dimension). Initially 59 items were adopted. 2) These items were analyzed through the index of content validity(CVI) and 53 items were selected which met more than 80% on the CVI. 3) The pretest was carried out with 87 patients with cancer. After the pretest results were analyzed by item analysis, 44 items were selected. A second test of content validity was conducted and 6 items were eliminated considering the 80% CVI. 4) To test for reliability and validity, data collection was done during the period from January 25, 1999, to February 26, 1999. The subjects for the test were 160 patients with cancer and 185 healthy persons. analysis, item analysis and multitrait-multimethod method to analyze validity. The findings are as follows : 1) The Cronbach's alpha coefficient for internal consistency was .92 for the total 38 items and .79, .82, .85, for the three dimensions in that order. 2) The item analysis was based on the corrected item to total correlation coefficient( .30 or more) and information about the alpha estimate if this item was dropped from the scale. 3) As a result of the initial factor analysis using principal component analysis and varimax rotation, one item was deleted because of factor complexity (indiscriminate factor loadings). In the secondary factor analysis, 7 factors with eigenvalue of more than 1.0 were extracted and these factors explained 56 percents of the total variance. The seven factors were labeled as 'family relationship', 'emotional condition', 'physical discomfort', 'meaning and goal of life', 'contextual stimuli', 'change of body image', 'guilt feelings'. 4) The convergence effect between this instrument and the life satisfaction scale was identified and there was significant positive correlation(r= .52, p= .00). The discriminant validity between this instrument and the depression scale(CES-D) was tested and there was significant negative correlation(r= -.50, p= .00). The instrument for accessing the suffering of patients with cancer developed in this study was identified as a tool with a high degree of reliability and validity. In this sense, this tool can be effectively utilized for assessment in caring for patients with cancer.

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Studies on Morphological and Physical Characteristics of Wheat and Barley Culms under Different Cultural Conditions 1. Effects of Top-Dressing Time of Nitrogen on Morphological and Physical Characteristics of Barley Culms (재배조건에 따른 맥간의 형태적 및 생리적 특성변화에 관한 연구 I. 질소추비시기가 맥간의 형태적 및 생리적특성에 미치는 영향)

  • Hong-Suk Lee;Chang-Hwan Cho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.14
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    • pp.117-121
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    • 1973
  • This experiment was conducted to study the effects of nitrogen top-dressed at the different growth stages on the morphological and physical characteristics of barley culm. The results obtained are summarized as follows: 1. By top-dressing of nitrogen in March, each internode length from the third to the fifth internode was shortened, and total fresh weight of the top, dry weight per unit culm, inside or outside culm diameter and thickness of culm were increased. Therefore these characteristics related to lodging indicated the beneficial changes for lodging resistance by top-dressing of nitrogen in March. 2. Both weight of culm at breaking and bending moment of culm at breaking, expressing lodging resistance of culm, were increased in the plots of nitrogen top-dressed in March. Accordingly lodging resistance became higher by top-dressing of nitrogen in March. 3. Both section modulus and secondary moment of inertia, expressing bending stiffness of culm, were increased by top-dressing of nitrogen in March. Accordingly lodging index, expressing comprehensive lodging resistance, became low by top-dressing of nitrogen in March. 4. Both spike weight and grain yield were increased by top-dressing of nitrogen in March. Consequently we came to the conclusion that the suitable top-dressing time of nitrogen was in March.

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The efficacy and safety of Montelukast sodium in the prevention of bronchopulmonary dysplasia

  • Kim, Sang Bum;Lee, Jang Hoon;Lee, Juyoung;Shin, Seung Han;Eun, Ho Sun;Lee, Soon Min;Sohn, Jin A;Kim, Han Suk;Choi, Byung Min;Park, Min Soo;Park, Kook In;Namgung, Ran;Park, Moon Sung
    • Clinical and Experimental Pediatrics
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    • v.58 no.9
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    • pp.347-353
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    • 2015
  • Purpose: The purpose of this study was to evaluate the efficacy and safety of Montelukast sodium in the prevention of bronchopulmonarydysplasia (BPD). Methods: The Interventional study was designed as a multicenter, prospective, and randomized trial, with open labeled and parallel-experimental groups, 66 infants were enrolled and allocated to either the case group (n=30) or the control group (n=36) based on gestational age (GA). Infants in the case group were given Montelukast sodium (Singulair) based on their body weight (BW). Zero week was defined as the start time of the study. Results: The incidence of moderate to severe BPD was not different between the groups (case group: 13 of 30 [43.3%] vs. control group: 19 of 36 [52.8%], P=0.912). Additionally, secondary outcomes such as ventilation index, mean airway pressure and resort to systemic steroids were not significantly different. There were no serious adverse drug reactions in either group, and furthermore the rate of occurrence of mild drug related-events were not significantly different (case group: 10 of 42 [23.8%] vs. control group: 6 of 48 (15.8%), P=0.414). Conclusion: Montelukast was not effective in reducing moderate or severe BPD. There were no significant adverse drug events associated with Montelukast treatment.

Study on the Ecological Restoration of Rock-exposed-cut-slope by Natural Topsoil Restoration Methods : In Case of Won-Ju Experiment (자연표토 복원공법에 의한 암절취비탈면의 생태적 복원에 관한 연구 : 원주사례지역을 중심으로)

  • Nam, Sang-Joon;Suk, Won-Jin;Kim, Nam-Choon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.2 no.4
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    • pp.54-63
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    • 1999
  • This study was conducted to suggest the ecological restoration and environmentally friendly revegetation technology for the rock-exposed cut-slopes by the Natural Topsoil Restoration Methods (NTRM) with the following restoration objectives; (1) prevention or reduction of wind and water erosion, (2) provision of food and cover for variety of animal species, (3) improvement of the visual or aesthetic quality of the disturbed slopes. On Nov. in 1995, the 5cm thick layer of artificial soil and 2cm thick layer of straw-mulching was attached at rock-exposed cut-slopes by NTRM without using anchor wire and anchor pin. The main results during four years surveying on the ground-coverage effect, plant growth, species diversity and importance values were summarized as follows. 1. Artificial soil attached at rock exposed cut-slopes was not eroded until recovered by tree and herbaceous vegetation in spite of not using anchor wire and anchor pin. Also it shows low soil hardiness and has almost the same amount of bacteria and fungi with in surrounding natural topsoil. 2. In 'combination for the woody vegetation', Lespedeza cyrtobotrya, Albizzia julibrissin, Rhus chinensis, Indigofera pseudo-tinctoria occupied upper layer vegetation. Since three years after seeding, Indigofera pseudo-tinctoria had overwhelmed the other woody plants and cool season foreign grasses, Erigeron canadensis, Taraxacum mongolicum, Commelina communis, Arundinella hirta (Thunberg) and Oenothera erythrosepala grows at lower part of the vegetation, 3. The heights of the Rhus chinensis grows 1.8m, Indigofera pseudo-tinctoria 2.0m, so it seems that the objectives of woody vegetation with native plants could be accomplished. 4. After 4 years later after seeding in 'combination for the herbaceous vegetation', the most dominant plant was Indigofera pseudo-tinctoria, the next was in order of cool-season grasses, Taraxacum mongolicum, Erigeron canadensis, lxeris dentata (Thunberg), Oenothera erythrosepala, Arundinella hirta (Thunberg). The diversity index in 'combination for woody vegetation' was higher than that in 'combination for the herbaceous vegetation'. The tendency of the intrusion of secondary succession plants was more effective in 'combination for the herbaceous vegetation' than in 'combination for the woody vegetation'.

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Variations of Mechanical Properties of Hallasan Trachyte with respect to the Degree of Weathering (풍화진행에 따른 한라산조면암의 역학적 특성변화)

  • Cho, Tae-Chin;Lee, Sang-Bae;Hwang, Taik-Jean;Won, Kyung-Sik
    • Tunnel and Underground Space
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    • v.19 no.4
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    • pp.287-303
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    • 2009
  • Rock mass in Baekrokdam at the summit of Hallasan in Jeju island is composed of two volcanic rock types: Baekrokdam trachybasalt at the eastern region and Hallasan trachyte at the western region. On-going rockfall and subsequent collapse of Baekrokdam wall rock are closely linked to the weathering of trachyte distributed in the western region of Baekrokdam. Samples of Hallasan trachyte showing different weathering grades had been collected and the polarizing microscopic observation, X-ray diffraction analysis and analysis for chemical weathering had been conducted. Formation of secondary minerals, especially clay minerals, by chemical weathering has not been identified, but the change of chemical weathering indices indicated that chemical weathering process had been proceeded to the degree for increasing and decreasing the contents of some chemical components. Changes in physical and mechanical rock properties due to weathering has also been examined. Artificial weathering test of freezing-thawing reveals that the process of crack initiation and propagation deteriorated the mechanical characteristics of Hallasan trachyte and $D_B$ = 1.5 or porosity = $20{\sim}21%$ would be the ultimate limiting value induced by the mechanical weathering processes.

Comparative Analysis on the Demand Estimation Method of Commercial Site: Focused on the Case of New Towns in Korea (상업용지 수요추정기법 비교분석 연구: 수도권 신도시 사례를 중심으로)

  • Lee, Sang-Jun;Yoon, Jeong-Joong
    • Land and Housing Review
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    • v.3 no.4
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    • pp.343-355
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    • 2012
  • The purpose of this paper is to propose reasonable improvements of demand estimation methods of commercial site through the case study. Thus, we investigated the problems and limitation of demand estimation methods and process applied to primary and secondary new towns in Korea. And we suggested the way to reduce error of demand estimation and to raise its objectivity. The result of case analysis is as follows; firstly, it was insufficient to consider location, hierarchy and change of land use like mixed-use development in commercial site. Secondly, improper comparable group or operated relevant index data in the same light were selected the aggregated unit requirement method such as comparative analogy method and planning guidelines. Thirdly, there were many cases that demand estimation value was amended arbitrarily, and it tends to occur a serious reliability problem. Therefore, to improve these problems and to make better use of demand estimation hereafter are required the sublation of arbitrary commercial sphere's settings, the making of comparative group considered development conditions, and putting forward objective revision basis.

Floristic study of Mt. Unbongsan in the basalt areas, Korea (현무암지대 운봉산의 관속식물상)

  • Kim, Jung-Hyun;Park, Hwan-Joon;Lee, Kyeong-Ui;Kim, Jin-Seok
    • Korean Journal of Environmental Biology
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    • v.38 no.3
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    • pp.371-387
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    • 2020
  • This study was conducted to investigate the flora of Mt. Unbongsan in the basalt areas of Korea. From the results of eight field surveys undertaken from March to October 2017, we identified 404 total taxa, representing 364 species, seven subspecies, and 33 varieties, which were placed in 256 genera and 91 families. The plant formation of Mt. Unbongsan is a deciduous broad-leaved and conifer mixed forest, which is common in the middle part of the Korean peninsula. Most of the mountain is covered by a young secondary forest, which is mainly composed of Quercus monglica and Pinus densiflora. Out of these 404 taxa, 193 were the first records for the region, six were endemic to Korea, three were listed on the Korean Red List of threatened species, 34 were floristic target species, and 40 were invasive alien species. The naturalized index(NI) percentage was 9.9%. Mt. Unbongsan has plant diversity, which was associated with the geomorphological landscapes. We considered that the composition and distribution of the species were affected by different environmental factors according to the presence of granite, taluses, block streams, drying ridges, valleys, puddles, wetlands, and streams.

Petrochemical Study on the Alkaline Gabbroic Host Rocks of Titaniferous Magnetite Deposits in Gonamsan, Yeoncheon-Gun, South Korea (고남산(古南山) 함(含)티탄자철광상(磁鐵鑛床)의 모암(母岩)인 알카리반려암질암의 암석화학적(岩石化學的) 연구(硏究))

  • Chang, Ho Wan;Yum, Byoung Woo;Park, No Young
    • Economic and Environmental Geology
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    • v.20 no.2
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    • pp.85-95
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    • 1987
  • The host rocks of titaniferous magnetite deposits in Gonamsan are alkaline gabbros, which are typical of undersaturated alkaline rocks in terms of the lack of normative quartz. According to field occurrences and petrographic features, these alkaline gabbros are divided into 3 rock types: coarse-grained and pegmatitic rock, medium-grained rock with equigranular texture, and layered cumulate rock. All these rocks mainly contain clinopyroxene(salite), plagioclase(An 43-66), pargasite, and ilmenite. The accessory minerals are apatite, sphene, quartz, and sometimes titaniferous magnetite. Pargasite, sphene, and quartz are considered to be secondary minerals formed by the reaction among clinopyroxene, plagioclase and Fe-Ti oxide at deuteric stage. Fe-Ti oxides generally occur as ilmenite in the alkaline rocks, and titaniferous magnetite in the ore deposits. Layered cumulate rocks are characterized by a recurrence of discontinuous thin mesolayer of clinopyroxene-pargasite within leucolayer mainly composed of plagioclase. Clinopyroxene is cumulus mineral whereas plagioclase, ilmenite and apatite occur as intercumulus minerals. According to the variation diagrams of oxide and trace element contents against the differentiation index, incompatible elements, such as Na, Ba and Sr, show positive correlations whereas compatible elements, such as Mg and Cr, show negative correlations. However some compatible elements, such as Co, Ni and V show irregular variations, reflecting relative cumulate status of cumulus and intercumulus minerals. On the de la Roche multicationic diagram, these alkaline gabbros are distributed along the differentiation curve of undersaturated alkaline series from alkaline basaltic composition through basanitic composition to tephritic composition. Layered cumulate rocks, which are distributed between basanitic composition and tephritic composition, reflect their cumulate character, slightly scattering away from the curve. The medium-grained rock shows higher contents in Ba, Sr and light rare earch elements than the coarse-grained and pegmatitic rock. The former shows two times higher contents of total rare earth elements than the latter, $while(La/Lu)_{cn}$ ratios maintain fairly constant values of 5.08~5.06 in these two rocks. This means that coarse-grained and pegmatitic rock, as compared with the medium-grained rock, was formed by the earlier differentiated magma but rare-earth element distribution pattern remained almost parallel during differentiation. From the data the above mentioned, these alkaline gabbros are considered to be comagmatic and to be formed by intrusions of differentiated magmas in its reservoir.

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Efficacy and Safety of Miniscalpel Acupuncture on Knee Osteoarthritis - A randomized controlled pilot trial -

  • Jun, Seungah;Lee, Jung Hee;Gong, Han Mi;Choi, Seong Hun;Bo, Min Hwang;Kang, Mi Suk;Lee, Geon-Mok;Lee, Hyun-Jong;Kim, Jae Soo
    • Journal of Pharmacopuncture
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    • v.21 no.3
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    • pp.151-158
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    • 2018
  • Objectives: We investigated the efficacy and safety of miniscalpel acupuncture (MA) for knee osteoarthritis (KOA) in an assessor-blinded randomized controlled pilot trial; this would provide information for a large-scale randomized controlled trial. Methods: Participants (n = 24) were recruited and randomly allocated to the MA group (experimental) or acupuncture group (control). The MA group received treatment once a week for 3 weeks (total of 3 treatments), while the acupuncture group received treatment two times per week for 3 weeks (total of 6 treatments). The primary outcome was pain as assessed by a visual analogue scale (VAS). The secondary outcomes (intensity of current pain, stiffness, and physical function) were assessed using the short-form McGill Pain Questionnaire (SF-MPQ) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Assessments were performed at baseline, 1, 2, and 3 during treatment and at week 5 (2 weeks after the end of treatment). Results: Of the 24 participants, 23 completed the study. Both groups showed significant improvements in VAS, SF-MPQ, and WOMAC. However, there were no significant differences between the MA and acupuncture groups. No serious adverse event occurred and blood test results were within normal limits. Conclusion: Our results suggest that although both MA and acupuncture provide similar effects with regard to pain control in patients with KOA, MA may be more effective in providing pain relief because the same relief was obtained with fewer treatments. A large-scale clinical study is warranted to further clarify these findings.