• Journal of Families and Better Life
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• v.14 no.3
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• pp.137-150
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• 1996

The purpose of this study is to investigate the level of the proporation of household expenditure item and the subjective burden of household due to the private educational expenses. The data used in this study included 761 housewives who have a child of the second grade or fourth grade of primary-school in Seoul. The findings of this study are as follows: First these six variables-educational level of mother household income place of residence grade of child number of child and the expected educational level of child-have significant effects on the private educational expenses. Second the proporation of food expense housing expense clothing expense and miscellaneous expense significantly differ with respect to the private educational expenses. Generally the proporation of household expenditure item and subjective burden are influenced more by the private educational expenses for school work than by the private educational expenses for talent.

• Communications of Mathematical Education
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• v.15
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• pp.281-286
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• 2003

The primary purpose of this study was to investigate how and to what extent 'representations' affect the students' understanding and the growth of understanding in a technology [GSP]-based collegiate mathematics classroom. There are three themes related as frames of the study along with this purpose, which are mentioned in the first chapter and extended in the second chapter: technology in mathematics education; images on computer screen - visualization and representation; understanding and growth of understanding. Three research questions guided this study: 1) How do students present each component of representations when they study 'transformations' in a technology [GSP]-based classroom? If there is any difference between the first and second presentation for each component, how are they different?; 2) How and to what extent do representations affect the students' understanding and the growth of understanding in a technology [GSP]-based classroom?; What types of benefits and obstacles are there when students study 'transformations' in a technology [GSP]-based classroom?

• Education of Primary School Mathematics
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• v.9 no.2 s.18
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• pp.107-118
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• 2005

The purposes of this study were to investigate the practice of performance assessment in elementary mathematics classes especially focused on 4th grade. To achieve this, three research questions were posed as follow: First, What do they prepare for performance assessment? Second, What kinds of tests do they use in mathematics performance assessment? Third, What kinds of difficulties do they have for performance assessment and what should be changed for a successful performance assessment in mathematics? To Answer the research questions, three 4th grade classes were selected from three different elementary schools in seoul and three teachers were interviewed. From the data analysis, several conclusion were drawn. First, a plan for mathematics performance assessment was not set by the class teacher who are in charge of the class. The main reason was lack of time. Second, in most of the assessment, written tests were used and the items in the tests were skill-oriented. Third, teachers thought that performance assessment was needed in mathematics. But lack of their time, knowledge and competency, it is difficult to do performance assessment in mathematics.

• Restorative Dentistry and Endodontics
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• v.6 no.1
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• pp.83-86
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• 1980

Fifty human maxillary second molars were injected with china ink, decalcified, cleared, and used in vitro study to determine the number of root canals, the frequency and location of lateral canals, canals per root, and frequency of apical deltas. The results were as follows. 1. The mesiobuccal root was found to contain a single primary canal in 62% of the teeth studied and two canals in 38% of the teeth studied. 2. In mesiobuccal roots with two canals, the seperated apical foramen appeared 24% of the specimens and the common apical foramen 14% of the specimens. 3. Of the 169 canals studied, 23.1% of the canals were found to contain lateral canals and these ramifications were mainly located in the apical third of the root.

• Education of Primary School Mathematics
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• v.6 no.1
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• pp.1-10
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• 2002

The objectives of the current study are on the practical use of geoboard in an elementary school class. To do this, we first investigate how come geoboard is significant in a practical use. Second, we present an example of practical use of geoboard connecting with the analysis of the 7th curriculum. Third, we investigate the results of geoboard which is applied to elementary school class. The results of this research are as follows: First, the instruction of using geoboard can give an interest and curiosity to all students. Second, right triangle, rectangle, square and so on can be easily constructed because geoboard is linked by dots. Third, by constructing figures on geoboard and comparing figures which is made by themselves, students could better understand the concept of figures rather than the explanation of teacher. fourth, students can be improved the ability of problem solving and spatial sense by providing experience for exploration. Fifth, students need not to have anxiety for error because geoband is used and so can be corrected easily.

• Journal of Information Science Theory and Practice
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• v.8 no.4
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• pp.20-28
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• 2020

In this study, the RDA DMP Common Standard (RDCS), a data model for implementing a machine actionable Data Management Plan (maDMP), was analyzed in four aspects. First, the twelve class models proposed by RDCS were analyzed. Second, whether the DMP attribute was included in the class attribute was analyzed. Third, we analyzed the namespace used for RDCS properties. Fourth, the values and identifiers used in RDCS properties were analyzed. As a result of the analysis, four directions for improvement were derived. First, it is necessary to add an academic record class to describe information such as papers and reports, which are representative academic documents. Second, the primary research institution, responsibility, resources, option attribute, and additional attributes are needed to describe the researcher's affiliation information. Third, it is necessary to additionally use a namespace such as Friend of a Friend that can be used universally. Fourth, the use of digital object identifier should be considered to identify academic literature.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10773-10777
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• 2015

Background: Treatment for breast cancer is mainly performed by surgical resection of primary tumors and chemotherapy. However, after tumor invasion and metastases, breast cancer is hard to control. Clarification of the pathogenic mechanisms would be helpful to the prognosis or therapy for the breast cancer. The aim of this study is to investigate the clinical and prognostic implications of legumain protein Materials and Methods: In this study, we examined mastectomy specimens from 114 breast cancer and matching, 26 adjacent non-cancerous tissues using immunohistochemistry. Results: The results indicated that positive expression of legumain protein in breast cancer was 51.8 % (59/114) and the positive expression of legumain protein in adjacent non-cancerous tissue was 11.5% (3/26). It appeared to be related with lymph node metastasis of breast cancer (p=0.02) and correlation analysis indicated that legumain expression was correlated positively with the estrogen receptor (ER) and mutant-type p53 expression (both p<0.05). Positive legumain expression was significantly associated with shorter overall survival time in breast cancer patients (log-rank p<0.01). Multivariate survival analysis suggested that the positive legumain expression was an independent predictor of poorer overall survival in patients with breast cancer (HR=0.24; 95%CI 0.11-0.65, p=0.03). Conclusions: Legumain might be a new potential biomarker for breast cancer, which may reflect the prognosis and overall survival.

• Radiation Oncology Journal
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• v.13 no.3
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• pp.267-275
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• 1995

Radiotherapy and chemotherapy can effectively control cancer but can also cause new second cancers to develop as long-term complications especially in childhood cancer. We experienced two patients with second malignant solid neoplasm who had been treated with radiation and chemotherapy for childhood cancers One female patient with rhabdomyosarcoma of the right popliteal fossa was treated with radiotherapy at total dose of 54Gy Three years and seven months later, osteosarcoma developed in the field of radiation therapy The other male patient with non-Hodgkin's lymphoma of the small bowel was treated with radiotherapy and leiomyosarcoma developed in the field of radiotherapy 18 years later. We reviewed the literature of the second malignant neoplasm in children in respect of risk factors. The risk for a second primary cancer following radiotherapy or chemotherapy emphasizes the need for life long follow-up of patients receiving such treatments, particularly patients treated for childhood cancers.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2014.04a
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• pp.352-357
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• 2014

Recently the construction of stations under railway lines and railway sections passing through central area of cities are increasing, calling for an urgent establishment of countermeasures against railway vibration and its subsequent second-phase noise. Of technology developed up to now, the most efficient countermeasure is the floating slab track, a track system isolated from the sub-structure by springs. Developed in this study, anti-vibration device for floating slab track (HLRM-High Load Rubber Mount) Haman station affiliated to the primary measurement was conducted in October 2012, one year after the second measurement after 2013 to be carried out in November and we want to change that. It is expected to raise awareness for the need of technology self-support and to make a meaningful contribution to mitigating vibration and noise produced by the next-generation high-speed railway.

• Journal of Microbiology and Biotechnology
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• v.32 no.6
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• pp.718-729
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• 2022

Esophageal squamous cell carcinoma (ESCC) is the most common primary esophageal malignancy with poor prognosis. Here, due to the necessity for exploring potential therapies against ESCC, we obtained the gene expression data on ESCC from the TCGA and GEO databases. Venn diagram analysis was applied to identify common targets. The protein-protein interaction network was constructed by Cytoscape software, and the hub targets were extracted from the network via cytoHubba. The potential hub nodes as drug targets were found by pharmacophore-based virtual screening and molecular modeling, and the antitumor activity was evaluated through in vitro studies. A total of 364 differentially expressed genes (DEGs) in ESCC were identified. Pathway enrichment analyses suggested that most DEGs were mainly involved in the cell cycle. Three hub targets were retrieved, including CENPF, CCNA2 (cyclin A), and CCNB1 (cyclin B1), which were highly expressed in esophageal cancer and associated with prognosis. Moreover, amentoflavone, a promising drug candidate found by pharmacophore-based virtual screening, showed antiproliferative and proapoptotic effects and induced G1 in esophageal squamous carcinoma cells. Taken together, our findings suggested that amentoflavone could be a potential cell cycle inhibitor targeting cyclin B1, and is therefore expected to serve as a great therapeutic agent for treating esophageal squamous cell carcinoma.