• Earthquakes and Structures
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• 제14권1호
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• pp.1-10
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• 2018

Seismic retrofitting of existing buildings and design of earth-quake resistant buildings are important issues associated with earthquake-prone zones. Use of metallic-yielding dampers as an energy dissipation system is an acceptable method for controlling damages in structures and improving their seismic performance. In this study, the optimal distribution of dampers for reducing the seismic response of steel frames with multi-degrees freedom is presented utilizing the uniform distribution of deformations. This has been done in a way that, the final configuration of dampers in the frames lead to minimum weight while satisfying the performance criteria. It is shown that such a structure has an optimum seismic performance, in which the maximum structure capacity is used. Then the genetic algorithm which is an evolutionary optimization method is used for optimal arrangement of the steel dampers in the structure. In continuation for specifying the optimal accurate response, the local search algorithm based on the gradient concept has been selected. In this research the introduced optimization methods are used for optimal retrofitting in the moment-resisting frame with inelastic behavior and initial weakness in design. Ultimately the optimal configuration of dampers over the height of building specified and by comparing the results of the uniform deformation method with those of the genetic algorithm, the validity of the uniform deformation method in terms of accuracy, Time Speed Optimization and the simplicity of the theory have been proven.

• 패션비즈니스
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• 제11권4호
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• pp.29-41
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• 2007

This study is to research how women aging from 20 through 40 Apperance -Mnagement Bhavior and care of their outer looks from a beauty treatment perspective. This research should help satisfy the wants of women who are the main clients of the beauty products and help the beauty industry to produce new products and also to help out on their marketing strategy. In order to search the general characteristics of our target women, Frequency Analysis was used, to find out the sub-factor of interest in beauty Factor Analysis and Reliability Analysis was used. In order to divide the group according to Degree of Apperance Concern 'sub-factor, cluster analysis, analysis of variance, Scheffe'-test, $X^2-test$ was used, and to find out the difference on how they care of beauty analysis of variance was used, and further more to summarize the result of analysis of variance Scheffe'-test was used. As a result, in all different ways of beauty caring, weight resisting, skin care and plastic surgery summed up similarly among the self-care group, hair care ended up with similar results among all three groups: self-caring group, no interest in beauty at all group, and the too conscious of other eyes group, and results on the interest rate of clothing ended up similarly among the other-eye conscious group, beauty care interest group, and the self-care group.

• Journal of the Korean Data and Information Science Society
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• 제22권1호
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• pp.57-64
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• 2011

이 연구에서는 최근 체육영재선정에 공통적으로 사용되고 있는 스포츠영재성 검사 항목과 코스타스 점수간의 연관성 분석을 통해 상대적으로 중요한 검사 항목과 그렇지 않은 검사 항목을 통계적으로 밝혀내는 데 목적이 있다. 이 연구를 위해 2010년도 서울지역 (강동구, 송파구, 노원구, 광진구 등)과 경기지역 (의정부시, 가평군, 구리시 등) H대학 체육영재양성사업에 지원한 201명의 초등학교 학생들의 자료가 사용되었으며, 육상 네 종목 (투척, 도약, 단거리, 중장거리), 수영 및 체조 종목의 코스타스 점수와 1차 스포츠영재성 검사에서 얻은 기본 체격, 체력 운동능력, 생리적 기능 정보를 이용하였다. 구체적으로 순수한 연관성 분석을 위해 피어슨상관계수와 편상관계수를 사용하였으며, 중요한 검사 항목 선택을 위해 단계적 회귀분석을 이용하였다. 그 결과 골연령, 체중, 흉위와 50m달리기, 하프스쿼트점프가 6개 코스타스 점수에 미치는 영향이 상대적으로 미약한 것으로 나타났다.

• 지능정보연구
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• 제9권1호
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• pp.23-51
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• 2003

인터넷 쇼핑몰에서 사례기반추론기법을 통한 유사상품의 탐색과 사용자 요구에 적합한 상품추천을 위해서는 다양한 요구에 부응할 수 있는 사례베이스의 구축이 우선되어야 한다. 그리고 구축된 사례베이스로부터 유사한 사례를 검색하여 재 사용하거나 필요시 수정하고, 그 결과를 다시 저장하는 기능이 요구된다. 사례기반 상품추천시스템 개발에 있어 가장 중요한 요소는 사례의 표현문제이다. 본 연구에서는 인터넷 수산물 쇼핑몰의 상품추천시스템에서 번들상품 구성문제(집안 이벤트 시 필요한 수산물의 집합)를 표현하는데 적합한 사례표현기법을 개발하며, 유사사례를 추출하기 위한 유사도 척도의 개발에 연구의 첫 번째 주안점을 둔다. 본 논문에서는 번들상품추천을 위한 사례표현기법으로 객체모델링(OMT)기법을 사용하고 있다. 또한 다양한 사례 속성 유사도 측정방법을 적용하며, 유사도 측정에서 분류법(taxonomy)의 의미와 그 적용방법을 제시한다.

• 한국강구조학회 논문집
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• 제16권1호통권68호
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• pp.123-134
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• 2004

본 연구에서는 효율적인 형상최적화를 위해 다단계 분할기법으로 트러스 구조물의 형상 최적화를 시도하였다. 1단계에서는 단면적을 설계변수로 하여 중량, 또는 체적을 목적함수로 하고 다하중 재하조건 하의 거동제약조건과 부가적인 제약조건을 고려하여 비선형 최적화 문제를 형성한다. 이 비선형 계획문제를 축차 선형계획 문제로 변환하여 개선된 허용방향법으로 최적화하였다. 이때 필요한 도함수는 다른 연구와 달리 효율적이라고 알려진 거동공간법으로 구하였고, 최적화 과정 중 이를 이용하여 부재력를 근사화 함으로써 계산의 효율성을 높였다. 2단계에서는 형상 설계변수만을 고려한 무제약 최적화 문제로 형성한 후 일방향 탐사기법을 적용하여 형상을 최적화하였다. 이와 같이 구성된 본 연구의 알고리즘을 몇 가지 트러스 구조물에 적용하여 본 알고리즘의 적용성과 효율성 및 타당성을 증명하였다.

• 한국의류학회지
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• 제30권11호
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• pp.1626-1635
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• 2006

The purpose of this study was to search for comfortable protective clothing for waste incinerator workers. The experimental protective clothing came in two types: one whose outer side made use of polypropylene film, and the inner side, a non-woven rayon fabric processed with charcoal with a 10% density (CF): and one whose outer side made use of polyolefine and polyamide films, and the inner side, a non-woven polypropylene fabric (NNCF). Experiments were conducted on five healthy adult women whose average age was 21. These experiments were conducted at a climate chamber, in which the temperature and relative humidity were set below $28{\pm}1^{\circ}C\;and\;50{\pm}10%$, respectively. Measured were the rectal temperature, the skin temperature, the sweating rate, the weight loss, the heart rate, the blood pressure, the temperature, and the relative humidity of a microclimate and subjective sensation. These were measured within a period of 60 min, consisting of a 20-min stable period, a 20-min exercise period (walking exercise for 2 miles/hr on a treadmill), and a 20-min recovery period. Through this experiment, the differences between the human body's physiological reactions to CF and NNCF clothing, and the human body's comfort levels when wearing these, were determined.

• Journal of Microbiology and Biotechnology
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• 제16권8호
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• pp.1262-1268
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• 2006

In the search for a novel cytotoxic substance from medicinal plants, HY53 ($C_{17}H_{32}O_2N_2$; molecular weight 296) was isolated from the leaves of Pata de Vaca (Bauhinia forficata). The growth of the HepG2 cells was inhibited in a dose-dependent manner when treated with 0.07 to 0.40 mM HY53 for 24 h (IC$_{50}$: 0.13 mM). Furthermore, nuclear DAPI staining revealed the typical nuclear features of apoptosis in the HepG2 cells exposed to 0.27 mM HY53, whereas a flow cytometric analysis of the HepG2 cells using propidium iodide showed that the apoptotic cell population increased gradually from 8% at 0 mM to 23% at 0.14 mM and 45% at 0.40 mM after being exposed to each concentration of HY53 for 24 h. Moreover, a TUNEL assay also exhibited the apoptotic induction of the HepG2 cells treated with HY53. To obtain further information on the HY53-induced apoptosis, the expression level of certain apoptosis-associated proteins was examined using a Western blot analysis. Treatment of the HepG2 cells with HY53 resulted in the activation of caspase-3, and subsequent proteolytic cleavage of poly(ADP-ribose) polymerase (PARP). Consequently, the results confirmed that the apoptosis in the HepG2 cells was induced by HY53 and the involvement of caspase-3-mediated PARP cleavage in the apoptotic process.

• Earthquakes and Structures
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• 제10권4호
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• pp.939-963
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• 2016

According to the new directives about the rational and efficient use of energy, thermal bridges in buildings have to be avoided, and the thermal insulation (TI) layer should run without interruptions all around the building - even under its foundations. The paper deals with the seismic response of multi-storeyed reinforced concrete (RC) frame building structures founded on an extruded polystyrene (XPS) layer placed beneath the foundation slab. The purpose of the paper is to elucidate the problem of buildings founded on a TI layer from the seismic resistance point of view, to assess the seismic behaviour of such buildings, and to search for the critical parameters which can affect the structural and XPS layer response. Nonlinear dynamic and static analyses were performed, and the seismic response of fixed-base (FB) and thermally insulated (TI) variants of nonlinear RC building models were compared. Soil-structure interaction was also taken into account for different types of soil. The results showed that the use of a TI layer beneath the foundation slab of a superstructure generally induces a higher peak response compared to that of a corresponding system without TI beneath the foundation slab. In the case of stiff structures located on firm soil, amplification of the response might be substantial and could result in exceedance of the superstructure's moment-rotation plastic hinge capacities or allowable lateral roof and interstorey drift displacements. In the case of heavier, slenderer, and higher buildings subjected to stronger seismic excitations, the overall response is governed by the rocking mode of oscillation, and as a consequence the compressive strength of the XPS could be insufficient. On the other hand, in the case of low-rise and light-weight buildings, the friction capacity between the layers of the applied TI foundation set might be exceeded so that sliding could occur.

• The Korean Journal of Physiology and Pharmacology
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• 제16권1호
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• pp.49-57
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• 2012

It has been shown that QGC isolated and purified from Rumecis folium found protective effects of gastritis and esophagitis which EXT is an ethanol extract of it. We examined acute toxicity and the general pharmacological action of QGC EXT to search for any side effects of it in rats, mice, guinea pigs, and cats. In a single dose toxicity study, QGC EXT didn't show toxicological effects in rats and mice, and the $LD_{50}$ was over 5 g/kg in both animals, and there were also no changes in weight, feed and water intake during these toxicological experimental periods. We examined the general pharmacological action on central controlled behavior responses, and peripheral organs including blood pressure, heart rate, respiration and gastrointestinal system, We found that there were no significant changes in body temperature, locomotors activity, stereotyped behaviors, sleeping time, and convulsion. In other studies, writhing reaction, normal body temperature, there did not appear to be any changes. The large intestine movement and electrical field stimulation-induced contraction was not changes by its EXT. In addition, the influences on blood pressure, heart rates, and respiration by QGC EXT were not found. These results indicate that QGC EXT may be very safe as a new drug, since its $LD_{50}$ was very high over 5 g/kg and any side effects were not found.

• Asian Pacific Journal of Cancer Prevention
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• 제17권11호
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• pp.4875-4883
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• 2016

Background and objective: Breast cancer-related lymphoedema (BCRL) is a disabling complication with long term impact on quality on life after breast cancer treatment. Its management remains a major challenge for patients and health care professionals; the goal of this overview was to summarize effects of different treatment strategies for patients with BCRL. Methods: A thorough search was undertaken to allow a systematic review or meta-analysis of treatments for BCRL. Two investigators independently selected studies and abstracted the data. Results: Combined physical therapy (CPT) with different combinations of surgery, oral pharmaceuticals, low-level laser therapy, weight reduction, mesenchymal stem cell therapy, kinesio tex taping, and acupuncture might be effective in reducing lymphoedema, but exercise demonstrated no obvious benefit. The results of direct comparisons showed CPT might be more effective than standard physiotherapy (ST). Manual lymphatic drainage (MLD) may not offer additional benefits to ST for swelling reduction, but could facilitate compression bandaging. MLD seemed to have similar effects with self-administered simple lymphatic drainage (SLD) or using an intermittent pneumatic compression pump (IPC). IPC might also not be associated with additional effectiveness for CPT. Efficacy of stem cell therapy vs. compression sleeve or CPT, as well as the effects of daflon and coumarin could not be established. Conclusion: Although many treatments for BCRL might reduce lymphoedema volume, their effects were not well established. The quality of many of the original studies in the included reviews was not optimal, so that in future randomized control trials are a high priority.