• BMB Reports
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• 제41권5호
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• pp.345-352
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• 2008

The cerebral microvessels possess barrier characteristics which are tightly sealed excluding many toxic substances and protecting neural tissues. The specialized blood-neural barriers as well as the cerebral microvascular barrier are recognized in the retina, inner ear, spinal cord, and cerebrospinal fluid. Microvascular endothelial cells in the brain closely interact with other components such as astrocytes, pericytes, perivascular microglia and neurons to form functional 'neurovascular unit'. Communication between endothelial cells and other surrounding cells enhances the barrier functions, consequently resulting in maintenance and elaboration of proper brain homeostasis. Furthermore, the disruption of the neurovascular unit is closely involved in cerebrovascular disorders. In this review, we focus on the location and function of these various blood-neural barriers, and the importance of the cell-to-cell communication for development and maintenance of the barrier integrity at the neurovascular unit. We also demonstrate the close relation between the alteration of the blood-neural barriers and cerebrovascular disorders.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 춘계학술대회논문집B
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• pp.956-961
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• 2000

This paper describes the design of a small size Alkali Metal Thermal to Electric Converter (AMTEC) which employs a capillary structure for recirculating sodium working fluid. The cycle is based on the simple and small capillary type ${\beta}"$ -alumina and wick tube element. The proposed cell consists of the 37 conversion elements with capillary tube of $50{\mu}m$ in diameter and the sealed cylindrical vessel of 22mm in outer diameter. Results on the cycle analysis of sodium flow and heat transfer in the cell showed that the expected power output was 4.65W and the conversion efficiency was 19% for the source temperature of 900K.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제50권7호
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• pp.351-363
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• 2001

This paper presents an experimental investigation on the heat trensfer characteristic of micro pipe (MHP) array with 38 triangular microgrooves. A heat pipe is an effective heat exchanger operating without external power. The heat pipe transfers heat by means of the latent heat of vaporization and two-phase fluid flow driven by the capillary force. The overall size of the MHP array can be put undermeath a microelectonic die and integrated into the electrronic package of a microelectronin device to dissipate the heat from the die. The MHP array is fabricated by micromachining with a silicon wafer and a glass substrate. The MHP was filled with water and sealed. The experimental results show the temperature decrease of 12.1$^{\circ}C$ at the evaporator section for the input power of 5.9 W and the improvement of 28% in the heat transfer rate.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1983년도 제17차 학술대회연제순서 및 초록
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• pp.20-20
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• 1983

40세 된 남자 환자로, 12일 전 스쿠바다이빙을 한 후에 나타난, 돌발성난청.이충만감.이명을 주소로 입원하였다. 발병 16 일째에 시험적 고실 개방술을 시행하였다. 등골-난원창 관절의 전방에서 밝은 액체가 누출되는 것을 볼 수 있었고, 그곳을 이수에서 Ep어낸 작은 지방조직으로 봉했다. 술후, 순음청력이 85㏈에서 15㏈로 좋아졌다. 그러나 4KHz 이상의 고음역에서는 변화가 없었다. 중이강을 보다 많이 탐사 함으로 해서 ,돌발성 난청을 일으키는 미노루공을 발견하는 데 많은 도움이 될 것이다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 추계학술대회 논문집
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• pp.572-575
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• 2005

A microlens connected to microfluidic channel is fabricated. The microlens is sealed with an elastomeric membrane which deforms by pressure of fluid driven by a syringe pump resulting in the shape change of the microlens. The optical properties of the microlens could be controlled by changing the microlens shape. The microlens system were made of an elastomer, PDMS, using molding from a photoplastic master patterned by UV photolithography. The test results show the optical property of the lens could be made into convex and concave type by applying the fluidic pressure positive and negative.

• Archives of Plastic Surgery
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• 제38권1호
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• pp.121-126
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• 2011

Purpose: Vaccum-assisted closure (VAC) has rapidly evolved into a widely accepted treatment of contaminated wounds, envenomations, infiltrations, and wound complications. This results in a sealed, moist environment where tissue is given the opportunity to survive as edema is removed and perfusion is increased. Many plastic surgeons now place a VAC device directly over the fasciotomy site at the time of the initial procedure. Large amounts of the fluid are withdrawn, and fasciotomies can be closed primarily sooner. This study was designed to observe the effect of VAC in preventing complications in snake bitten hands. Methods: In our study of three cases of snake bite, three of them underwent the VAC treatment & fasciotomy of the wound in the hand. This cases, the posterior compartment of the hand was bitten for a few days, releasing incisions were made of the posterior hand and 125 mmHg of continuous vacuum was applied to fasciomy incision site and the biting wound. The dressings were changed three times per week. Results: Our study examining the effects of applied vacuum in preventing snake bite wounds showed that the incidence of tissue necrosis and compartment syndrome was significantly lower for vacuum-treated wounds than for conservative wounds. Serum myoglobin, CK-MB, and CPK levels measured after fasciotomy incision were significantly decreased. We obtained satisfactory results from early dorsal fasciotomy, drainage of the edema with the VAC system, and then primary closure. The postoperative course was uneventful. Conclusion: Envenomation is a term implying that sufficient venom has been introduced into the body to cause either local signs at the site of the bite and/or systemic signs. Use of the vacuum-assisted closure device in snake bite can result in a decreased rate of tissue necrosis, lymphatic fluid collection, hemolytic fluid collection, and edema. Early fasciotomy of the dorsal hand and VAC apply is the alternative treatment of the snake bite.

• 터널과지하공간
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• 제32권4호
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• pp.272-284
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• 2022

본 연구에서는 개발 중인 전단농화유체(shear thickening fluid) 기반의 발파전색재료와 밀폐 플러그 장치의 효과를 평가하기 위하여 터널발파를 수행하였다. SAV-Cut공법을 적용하고 있는 터널현장에 STF 단일전색 및 STF 전색재를 플러그와 결합하여 적용하였고, 기존 방식의 모래전색을 적용한 케이스와 굴진율 및 파쇄입도를 비교하였다. 터널 굴진율은 3차원 레이저 스캐너를 이용하여 평가하였다. STF 전색재료와 STF 전색재료에 플러그를 결합한 경우 모래전색 대비 각 5.7, 5.36% 정도 굴진율이 향상되는 것을 확인하였다. 파쇄입도의 경우 STF 전색재료를 적용하였을 경우 가장 좋게 나타났으며, 모래 전색케이스와 비교하였을 때 약 61% 파쇄입도가 감소하였다. 그러나 플러그 장치적용에 따른 뚜렷한 발파 효과 향상은 관찰되지 않았다.

• 한국건축시공학회지
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• 제18권1호
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• pp.25-31
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• 2018

본 연구는 순환유동층보일러(CFBC)에서 발생되는 바닥재와 비산재를 활용한 저강도 고유동 채움재를 개발하였다. CFBC비산재(CFBC-F) 와 CFBC바닥재(CFBC-B)는 불규칙한 입자 형상을 가지고 있는 것과 유해성 분석결과 환경적으로 안정한 것을 확인하였다. CFBC-F가 첨가될 경우 단위수량이 증가하였다. 길이변화율은 기건양생 조건에서는 -0.05~-0.50% 범위의 수축이 발생하였으며, 밀봉양생 조건에서는 0.1~0.6%의 범위의 팽창이 발생하였다. 압축강도는 밀봉양생 조건에서는 장기적으로 수화반응을 진행할 수 있는 충분한 수분이 남아 있어 기건양생 조건 대비 압축강도가 증가 하는 것을 확인하였다. 본 연구에서 도출된 결과는 저강도 고유동 채움재 개발 및 CFBC 석탄재 활용에 있어 도움이 될 것이라 생각된다.

• 한국산업보건학회지
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• 제16권4호
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• pp.364-374
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• 2006

Natural ventilation technique could be the substitute for or the complement to the local exhaust ventilation system in the sense of protecting work environment. Moreover, it has many strong points ; almost no mechanical parts, no energy use and no noise. If applied appropriately, it could have the very high ventilation rate and save a lot of energy expense. But, it depends on the outdoor environment, especially temperature and wind speed/direction. Predicting the capacity of natural ventilation is not an easy job because it comes from both buoyancy and wind effect. Another problem is too much flow through the ventilator especially in winter time due to too much difference between indoor and outdoor temperature. Thus some ventilators in industries are sealed by door or plastic sheet, resulting in bad work environment. Various types of dampers are used to control the flow rate through ventilators. The capabilities of flow control by damper has not been estimated. In addition, it was not tested whether the damper could obstruct the flow through ventilator when fully opened. To answer these questions, 4 types of dampers were tested by using computational fluid dynamics. 10 different configurations includes no damper, full open and half open. Flow rates were estimated and airflow fields were analysed to clarify the before-mentioned questions. The dual type damper was the best choice for controling the capability of ventilator. In addition, the upward grill type damper was the best for not obstructing the air flow when fully opened.

• 한국유체기계학회 논문집
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• 제14권3호
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• pp.23-27
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• 2011

Due to a roots type medium vacuum pump is operated in condition of $1{\sim}10^{-3}$ torr vacuum, it could be applied for production and process of industrial parts, such as precise processing, vaporization, enrichment, separation, casting, metaling, welding, transportation. Therefore, the demand of this pump is increasing nowadays in our industrial markets of semiconductor, electric, electronic, automobile, material, environmental and transporting industries. However, the pumps are almost imported, because the domestic pumps are inferior in fields of vacuum range as under $10^{-1}$torr, relevant techniques(design, fabrication, casting, test, etc.) to the imported ones. In this study, essential parts of the development pump are designed with using of CFD and 3D decodes, FEM for analysing strength and deformation, generated heat, vibration and noise control, and are casted with using of mechanochemistry techniques for decreasing of weights, increasing of heat resistances and abrasion durability of materials for pump caing and impellers especially. Besides, in order to achieve ultimate vacuum around $10^{-3}$torr, this pump is composed of 6 stages, among which 1st stage is operated separately from remained stages. Additionally, a test rig for prototype pumps(300$m^3/h$ and 2,500$m^3/h$) is designed and procured as to apply for multi-staged rootz type vacuum pump, with modification of the test method recommended by KS B 6314 "Positive-displacement oil-sealed rotary vacuum pumps".