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Inter-device agreement between spectral domain optical coherence tomography, ultrasound biomicroscopy, and gonioscopy in evaluating the iridocorneal angle in normotensive dogs

  • Su An Kim;Jaeho Shim;Seonmi Kang;Kangmoon Seo
    • Journal of Veterinary Science
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    • v.24 no.4
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    • pp.34.1-34.12
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    • 2023
  • Background: There has not been a thoroughly reported study of the comparison between spectral domain-optical coherence tomography (SD-OCT) with both ultrasound biomicroscopy (UBM) and gonioscopy on the evaluation of the iridocorneal angle (ICA) in dogs. Objectives: To investigate the diagnostic value of SD-OCT for the early detection of narrowing ICA by comparing and assessing inter-device agreement in anterior chamber angle (ACA) measurements obtained by SD-OCT and UBM, and ICA evaluations by gonioscopy. Methods: A total of 28 eyes from 28 client-owned dogs with normal intraocular pressure were included for examination. The ACA and angle opening distance (AOD) were measured from the SD-OCT and UBM images, and gonioscopy images were analyzed using the ICA grade and ZibWest angle index. Results: The mean ACA and AOD for SD-OCT were 28.31° ± 5.37° and 658.42 ± 219.90 ㎛, and for UBM, 28.34° ± 5.82° and 859.29 ± 221.80 ㎛, respectively. The mean difference in ACA between the average values of SD-OCT and UBM measurements was 0.03° with a 95% limit of agreement (LoA) span of 16.2°, indicating positive agreement; that in AOD was 200.85 ㎛ with a 95% LoA span of 1,110.95 ㎛, indicating poor agreement. The Pearson correlation coefficient of the ACA of SD-OCT and ZibWest indices of gonioscopy was 0.624, indicating strong agreement; that of UBM and gonioscopy was 0.43, indicating moderate agreement. Conclusions: SD-OCT is well tolerated by canine patients due to its non-contact method and might be an alternative option for early screening of ICA narrowing in clinical settings.

Latarjet operation carries three times the risk of failure in seizure versus non-seizure recurrent anterior dislocation of the shoulder joint: outcome of a systematic review with meta-analysis

  • Alok Rai;Dushyant Chouhan;Sandeep Kumar Nema;Arkesh Madegowda;Rudra Narayan;Bikram K. Kar
    • Clinics in Shoulder and Elbow
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    • v.27 no.2
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    • pp.160-168
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    • 2024
  • Background: Recurrent anterior shoulder dislocation (RASD) in cases of seizure disorders (SDs) total 50%-80% of all SD-associated shoulder instabilities. Based on the extent of bone loss, treatment options include bony and soft-tissue reconstructions, arthroplasty, and arthrodesis. The primary objective of this paper was to review the treatment options for RASD in SDs. Methods: Several bibliographic databases were searched for RASD treatment options in SD patients. The demographic outcome measures, the failure rate (defined as the relative risk of recurrence of dislocation postoperation), and the postoperative seizure recurrence rate were recorded. Results: We pooled 171 cases (187 shoulders) from 11 studies. Of these, one, five, two, two, and one reports studied Bankart's operation with remplissage (27 cases/29 shoulders), the Latarjet procedure (106/118), bone block operation (21/23), arthroplasty (11/11), and arthrodesis (6/6), respectively, in treating SD-associated RASD. The relative risk of failure between SD and non-SD patients was 3.76 (1.36-10.38) after the Latarjet operation. The failure rates were 17% and 13% for Bankart's operation with remplissage and the Latarjet procedure in SD patients, respectively, but 0% each for bone block operation, arthroplasty, and arthrodesis. The total rate of seizure recurrence after operation was 33% of the pooled cases. Conclusions: SD recurrence in the postoperative period, the size of the bone block, and the muscular attachments to a small coracoid autograft are the determinants of failure among various reconstructive operations in SD-associated RASD.

Physiological Responses of Starry Flounder Platichthys stellatus during Freshwater Acclimation with Different Speeds in Salinity Change (염분변화 속도를 달리한 담수순화 과정에서 강도다리 Platichthys stellatus의 생리학적 반응)

  • Kim, Young-Soo;Do, Yong-Hyun;Min, Byung-Hwa;Lim, Han-Kyu;Lee, Bok-Kyu;Chang, Young-Jin
    • Journal of Aquaculture
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    • v.22 no.1
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    • pp.28-33
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    • 2009
  • Physiological responses (hematological factors, cortisol, glucose, osmolality, $Na^+$, $K^+$ and $Cl^-$) in starry flounder Platichthys stellatus were investigated during freshwater acclimation in the conditions of different speeds in salinity change with acute-decrease (AD) or stepwise-decrease (SD I and II). In AD of acute-decrease salinity, hematocrit (Ht), red blood cell (RBC) and hemoglobin (Hb) were rapidly increased more than SD I of stepwise-decrease salinity. But in case of SD II, Ht, RBC and Hb were no significant difference from beginning to end of this experiments. In AD, cortisol level significantly increased from $2.1{\pm}1.0{\mu}g/mL$ at the beginning to $13.7{\pm}0.2{\mu}g/mL$ at 6 hours and recovered to the basal levels ($3.1{\mu}g/mL$) at 10 days. In SD I, cortisol level was significantly increased from $2.1{\pm}1.0{\mu}g/mL$ at the beginning to $13.6{\pm}0.6{\mu}g/mL$ at 6 hours and recovered to the basal levels ($3.1{\pm}0.4{\mu}g/mL$) at 10 days. In SD II, cortisol level was a little increased from $2.1{\pm}1.0{\mu}g/mL$ at the beginning to $10.5{\pm}2.5$, $10.8{\pm}5.6{\mu}g/mL$ at 6, 12 hours and recovered to the basal level at 48 hours. Glucose level of AD, SD I, II were no significant difference from beginning to end of this experiments. Osmolality was $286.8{\pm}3.3\;mOsm/kg$ at the beginning. In SD II of stepwise-decrease, osmolality was no significant difference during rearing in freshwater (FW). But AD of stepwise-decrease and SD I of stepwise-decrease, osmolality was a little decreased end of this experiments. In AD of acute-decrease, only $Cl^-$ level was showed no significant difference from beginning to end of experiment and $Na^+$, $K^+$ levels were decreased. In case of SD I, $Cl^-$ level was showed no significant difference from beginning to end of experiment and $Na^+$, $K^+$ levels were decreased.

Isolation and morphological characterization of natural killer cell in the sprague-dawley(SD) rats (Sprague-dawley(SD) 랫드에서 natural killer cell의 분리 ·동정 및 형태적 특징)

  • Kang, Kyung-sun;Lee, Yong-soon
    • Korean Journal of Veterinary Research
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    • v.32 no.2
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    • pp.245-250
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    • 1992
  • This study was performed to demonstrate the presence of large granular lymphocyte(LGL) in Sprague-Dawley(SD) rats and morphologically observe NK cell and also establish the method of isolation of natural killer cell in SD rats. By percoll discontinuous density gradients centrifugation, highly enriched LGL population were shown to fraction 2(border line between 44.2% and 50.8%). LGL were shown to bind selectively to YAC1 mouse lymphoma cell. This fraction expressed very high NK cell cytolysis. Therefore, we thought that LGL have NK activity in SD rats. The Morphology of rat LGL is very similar to that of human LGL. These cells have an eccentric kidney-shaped nucleus. Their most distinctive feature was their cytoplasmic azurophilic granules. Another distinguishing feature of rat LGL was their high cytoplasmic : nuclear ratio. It was concluded that LGL played a role part in mediating natural killer activity in this species.

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Structural Performance of Steel Pipe Splice for SD500 High-strength Reinforcing Bar under Cyclic Loading

  • Kim, Hyong-Kee
    • Architectural research
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    • v.10 no.1
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    • pp.13-23
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    • 2008
  • It is the purpose of this study to evaluate the structural performance of steel pipe splice for SD500 high-strength reinforcing bar, through a cyclic loading test. The experimental variables adopted in this study include the development length of rebar, the type of sleeve, and size of reinforcing bar, among others. The results of this study showed that the developed steel pipe splice system for SD500 high-strength reinforcing bar, retained the structural performance required in domestic, ACI and AIJ code. It is considered that the study result presented in this paper can be helpful in developing a reasonable design method for a steel pipe splice system for SD500 high-strength reinforcing bar.

Hybrid Multiple Description Video Coding Using SD/MD Switching (SD/MD 전환을 이용한 하이브리드 다중 표현 동영상 압축 방법)

  • Kim Il Koo;Cho Nam Ik
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2003.11a
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    • pp.27-30
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    • 2003
  • 본 논문에서는 하이브리드 다중 표현(hybrid multiple description) 개념을 이용하여 에러가 발생하기 쉬운 환경에서 사용될 수 있는 강인한 동영상 압축 알고리듬을 제안한다. 다중 표현 압축은 단일 표현 압축(single description coding. SDC) 보다 패킷 손실 율(packet loss rate, PLR)이 높은 환경에서 에러에 더 강인성을 갖는다. 그러나 PLR 이 낮은 환경에서는 과도한 중복량(redundancy) 때문에 성능이 저하되는 문제가 발생한다 이러한 MDC 의 문제를 해결하기 위해서 채널 환경에 따라 SD/MID 를 전환할 수 있는 방법을 제안한다. 좀더 자세히 설명하면, 낮은 PLR 에서는 압축 효율을 위하여 SDC 를 사용하고 높은 PLR 환경에서는 에러에 대한 강인성을 위해 MDC 를 사용한다. SD/MD 전환을 최적화시키기 위해 비트율-왜곡 최적화 프레임웍(rate-distortion optimization framework)을 사용한다. 부호화시에 복호기에서의 왜곡(distortion)을 정확히 예측하기 위해서 ROPE(recursive optimal per-pixel estimate) 방법을 사용한다. 모의 실험 견과 제안된 SD/MD 전환 방법이 기존의 SDC-ROPE 와 MDC-ROPE 보다 모든 에러 환경에서 더 효과적임을 알 수 있다.

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Effect of Silver sulfadiazine on the Skin Cell Proliferation and Wound Healing Process in Hairless Mouse 2nd degree Burn Model (설파디아진은의 피부세포 증식 및 화상모델에 있어서의 상처치유과정에 미치는 영향)

  • Cho, Ae-Ri
    • Journal of Pharmaceutical Investigation
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    • v.32 no.2
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    • pp.113-117
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    • 2002
  • Cyto-toxic effect of silver sulfadiazine (Ag-SD) on keratinocytes and its implication on wound healing process were investigated in $2^{nd}$ degree bum hairless mouse model. As a dermal model, HaCat (immortalized keratinocytes) monolayer culture in DMEM with 10% FBS was used. Cyto-toxicity of Ag-SD was estimated by measuring the cell viability using neutral red assay after adding the drug. The $2^{nd}$ degree bum was prepared on hairless mouse back skin (1 cm diameter) and dressings with Ag-SD were applied for 96 hr. The process of re-epithelialization and the presence of inflammatory cells were investigated and histology with Hematoxylin-Eosin staining was performed. Ag-SD displayed highly cyto-toxic effect on cultured HaCat cells in a concentration dependent manner $(1-100\;{\mu}g/mL)$. Topical application of Ag-SD (2%) could control the infection: no inflammatory cells were observed in histology. However the cyto-toxic effect of Ag-SD on skin cells induced the impairment in epidermal regeneration.

Dijkstra's Search-Based Sphere Decoding with Complexity Constraint (제한된 연산량을 갖는 Dijkstra 탐색 기반의 스피어 디코딩)

  • Yoon, Hye-yeon;Kim, Tae-Hwan
    • Journal of the Institute of Electronics and Information Engineers
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    • v.54 no.7
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    • pp.12-18
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    • 2017
  • This paper presents a Dijkstra's-search-based sphere decoding (SD) algorithm with limited complexity for the symbol detection in MIMO communication systems. The Dijkstra search-based SD is efficient to achieve a near-optimal error rate in the MIMO symbol detection, but has a critical problem in that its complexity is variable and can correspond to that of the exhaustive search in the worst case. The proposed algorithm limits the computations while achieving a near-optimal error rate. Simulation results show that the error rate is near optimal even with the limited complexity.

Changes in Oil, Tannin, Total Sugar Contents and Yield after Flowering in Peanut

  • Lee, Sung-Woo;Park, Chang-Hwan;Kang, Chul-Whan;Kim, Sok-Dong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.44 no.2
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    • pp.159-162
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    • 1999
  • This study was carried out to determine the optimum harvest date of unshelled immature peanuts and dried kernels from 60 to 120 days after flowering. Fresh pod yield of spanish-type variety, 'Shaedl-tangkong(SD)' reached a peak of 9,140kg/ ha at 70 (days after flowering(Aug. 13) while that of virginia-type variety, 'Daepoongtangkong(DP)' reached a peak of 8,820kg/ha at 90 days(Sept. 11) after flowering. SD and DP showed maximum fresh kernel yield of 6,090 and 6,470kg/ha at 90 days after flowering (Sept. 11), respectively, while dry kernel yield reached a peak of 3,300 and 3,720kg/ha at 110 days(Oct. 1), respectively. Oil content of SD and DP were the highest at 90 days and 100 days after flowering, respectively and the oil content of two varieties increased rapidly from 60 to 90 days. Tannin content of the seed hull of SD increased continuously until 110 days after flowering while that of DP maximized at 100 days. The tannin content of the two varieties increased rapidly from 60 to 100 days. Total sugar of SD and DP showed highest content at 60 days and 70 days after flowering, respectively and suger content decreased very rapidly until 80 days and after that sugar content kept nearly constant. Oil, tannin and total sugar content of spanish-type SD were higher than those of virginia-type DP.

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Archetypical System Dynamics Modeling Approach: Constructing C-S-I model into smart work system

  • Kim, Dong-Hwan;Lee, Eun-Kyu
    • Korean System Dynamics Review
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    • v.16 no.3
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    • pp.97-107
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    • 2015
  • 본 논문은 최근 다양한 사회 분야에 있어서 IT 기술이 적용되는 과정을 SD 모델링 방식을 사용하여 연구한 경험과 발견을 서술하고자 한다. 모델의 초기 단계에서 우리는 다양한 사회 분야마다 다른 SD 모델을 만들 것이냐 아니면 기본적으로 유사한 모델 구조를 취할 것이냐를 선택해야 했다. 사회 분야마다 다른 구조의 SD 모델을 만들면, 상호간의 구조와 시뮬레이션 결과를 비교하기 어렵다. 하지만 상호 모델 구조를 유사하게 구축하려고 하니, 서로 다른 모델링 팀들간의 의사소통에 노력과 시간 소비가 지나치게 커져 갔다. 이러한 어려움을 극복하기 위하여 본 연구에서는 시스템 다이내믹스 모델링에도 시스템 사고의 원형적 피드백 루프에서와 같은 원형적 SD 모델을 만들고, 이를 사회 각 분야에 적용하는 방식을 취하고자 하였다. 먼저 최근 IT 기술 발전을 이끌어 가는 핵심적인 요소로서 클라우드 컴퓨팅, 스마트 기기, 사물 인터넷을 선정하고 이들간의 상호 관계성을 표현하는 SD 모델을 만들었다. 이를 원형(archetype)으로 하여, 교육, 의료, 원격 근무 등 사회 각 분야의 IT 확산 과정에 적용하여 모델링을 하고 시뮬레이션을 하여 상호 비교하면서 정책 시사점을 논의할 수 있었다. 본 논문에서는 이 중에서 원격 근무(smart work)에 관한 적용 사례를 제시함으로써, SD 모델링에 있어서 원형적 접근 방법의 가능성을 탐색한다.