• Title/Summary/Keyword: Screen Design

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Expression of MEK1 Fusion Protein in Yeast for Developing Cell Based Assay System, a Major Substrate of LeTx (Yeast내에서 MEK1 융합 단백질 발현 및 Lethal Factor 활성 검증)

  • Hwang, Hye-Hyun;Kim, Joung-Mok;Choi, Kyoung-Jae;Park, Hae-Chul;Han, Sung-Hwan;Chung, Hoe-Il;Koo, Bon-Sung;Park, Joon-Shik;Yoon, Moon-Young
    • Korean Journal of Microbiology
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    • v.42 no.3
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    • pp.195-198
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    • 2006
  • Lethal toxin is a critical virulence factor of anthrax. It is composed two protein: protective antigen (PA) and lethal factor (LF). PA binds to specific cell surface receptors and, forms a membrane channel that mediates entry of LF into the cell. LF is a zinc-dependent metalloprotease, which cleaves MKKs [MAPK (mitogen-activated protein kinase) kinases] at peptide bonds very close to their N-termini. In this study, we suggest application of cell-based assays in the early phase of drug discovery, with a particular focus on the use of yeast cells. We constructed MEK1 expression system in yeast to determine LF activity and approached cell-based assay system to screen inhibitors, in which the results covering the construction of LF-substrate in yeast expression vector, expression, and LF-mediated proteolysis of substrate were described. These results could provided the basic steps in design of cell-based assay system with the high efficiency, rapidly and easy way to screening of inhibitors.

Implementation of Efficient Mobile Monitoring System of the GreenHouse Environment Data (온실 환경 데이터의 효과적인 모바일 모니터링 시스템 구현)

  • Seo, Jung-Hee;Park, Hung-Bog
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.3
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    • pp.572-579
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    • 2009
  • A monitoring system needs many parameters to increase devices for monitoring data and to support various services. In particular, monitoring the status of a device in a wireless mobile environment has a difficulty in displaying multi data in a limited screen size, and transfer of the status data of a device into a network is largely related with network traffic. The research aims at designing a control board that collects data in order to effectively manage a greenhouse environment system. Also, the research tries to appropriately operate devices, environment data monitoring, and the control of each device by realizing a multiplexed interface based on a web. Thus, in the case in which a distributed client was a computer, monitoring and control were obtained with a web browser through the Lab VIEW web server of a server or local control module in order to effectively monitor and control according to the status of a user. In the case in which a client was a PDA, application of a wireless mobile considering the scale and data processing capacity of a displayer was connected. As a result of the research, we could confirm a satisfactory outcome from the viewpoint of a human-centered design by supplying adaptability and mobility according to the environment of a user.

New Method Proposal of Animation Screening by using Projection Mapping and Pop-up Book - Hybrid Animation Theater - (팝업북과 프로젝션 맵핑을 이용한 새로운 애니메이션 상영 방식 제안 - Hybrid Animation Theater -)

  • Lim, Kyoung-Hun
    • Cartoon and Animation Studies
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    • s.39
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    • pp.133-156
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    • 2015
  • With development of media and technology animation are seeking a variety of a genre fusion. I would like to propose a new animation screening method using a projection mapping and a popup book. I redesigned the existing method of watching the animation to a new experience by projecting the image on a three-dimensional structure instead a flat screen. This screening method was inspired by preceded works which were made by the fusion of a projection mapping and a popup book. Through analysis of them, I found the merits, shortcomings and clarified the difference of each works. I called this method "Hybrid Animation Theater" because it is fused the various areas - Theater, Projection mapping, Pop-up book, Animation, and Installations, etc. also studied for its architectural features and design. After I designed a prototype to demonstrate the possibilities, the limitations and shortcomings, I could suggest next research directions.

A Study on Red Tide Monitoring system using Wireless Sensor Network (무선센서네트워크를 이용한 적조모니터링 시스템 구축을 위한 연구)

  • Min Heo;Mo Soo-Jong;Yim Jae-Hong;Kim Ki-Moon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.489-492
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    • 2006
  • Red tide occurred sporadically in early 90s. But It is happening extensively by global warming. So, Airline observation, Red tide buoy development, and Red tide alarm system research is progressing for monitor ring. However, study to early forecast red tide and red tide alarm system did not exist hard. This paper proposed development that design and implementation red tide database of using wireless sensor network. There are GPS, Water Temperature sensor, Oxygen sensor, and Turbidity sensor in each node. And data is stored to red tide database through Ad-hoc network. This data is integrated and analyzed. So, forecast red tide. And red tide database has red tide data that happen at past. This is utilized to comparative analysis data for red tide estimate. Main screen displays position of node and measured value in electron map. Much studies must be backed for this a study. But I think that contribute to analyze red tide data by red tide database construction.

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Real-Time Remote Display Technique based on Wireless Mobile Environments (무선 모바일 환경 기반의 실시간 원격 디스플레이 기법)

  • Seo, Jung-Hee;Park, Hung-Bog
    • The KIPS Transactions:PartC
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    • v.15C no.4
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    • pp.297-302
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    • 2008
  • In case of display a lot of information from mobile devices, those systems are being developed that display the information from mobile devices on remote devices such as TV using the mobile devices as remote controllers because it is difficult to display a lot of information on mobile devices due to their limited bandwidth and small screen sizes. A lot of cost is required to design and develop interfaces for these systems corresponding to each of remote display devices. In this paper, a mobile environment based remote display system for displays at real times is proposed for continuous monitoring of status data for unique 'Mote IDs'. Also, remote data are collected and monitored through sensor network devices such as ZigbeX by applying status perception based remote displays at real times through processing ubiquitous computing environment data, and remote display applications at real times are implemented through PDA wireless mobiles. The system proposed in this paper consists of a PDA for remote display and control, mote embedded applications programming for data collections and radio frequency, server modules to analyze and process collected data and virtual prototyping for monitoring and controls by virtual machines. The result of the implementations indicates that this system not only provides a good mobility from a human oriented viewpoint and a good usability of accesses to information but also transmits data efficiently.

A study on the standard of effective fire facilities for the Atrium (아트리움 공간의 효과적인 방화설비 기준연구)

  • Choi, Don-Mook;Kim, Jae-Woon;Min, Se-Hong
    • Journal of Korean Institute of Fire Investigation
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    • v.6 no.1
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    • pp.49-66
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    • 2005
  • The purpose of this study is to present reference data to be considered in designing fur the fire safety of atrium buildings. This study deals with the characteristics of atrium buildings in the fire safety aspect, analysis of fire examples and foreign fire codes of atrium space. And con-crete factors to be consigning fur the fire facilities of atrium buildings are presented. Recently many atrium spaces have been built in Korea. They provide new experience of space with resident and pedestrians. However, because of the lack of knowledge in design principle and disaster prevention, large loss of lives is expected in an emergency situation. cion. Therefore safety ensuring from the case is urgently needed. The following is the summary on the standard of effective fire facilities for the atrium. 1. The smoke control. inside atrium must use the machine ventilation in the atrium. 2. It is desirable to divide the section between atrium and nearby living room by anti-smoke screen in order to prevent damage by smoke when fire break out. 3. It is desirable to instill an excellent fire detector like infrared light detector as a replacement of old one. 4. It is desirable to transfer from closed operating sprinkler to fire-cycle sprinkler equipment or ablative sprinkler when the height is lower than 20m.

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Optical Monte Carlo Simulation on Spatial Resolution of Phosphor Coupled X-ray Imaging Detector (형광체 결합형 X선 영상검출기의 공간 해상력 몬테카를로 시뮬레이션)

  • Kang, Sang-Sik;Kim, So-Yeong;Shin, Jung-Wook;Heo, Sung-Wook;Kim, Jae-Hyung;Nam, Sang-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.328-328
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    • 2007
  • Large area matrix-addressed image detectors are a recent technology for x-ray imaging with medical diagnostic and other applications. The imaging properties of x-ray pixel detectors depend on the quantum efficiency of x-rays, the generated signal of each x-ray photon and the distribution of the generated signal between pixels. In a phosphor coated detector the light signal is generated by electrons captured in the phosphor screen. In our study we simulated the lateral spread distributions for phosphor coupled detector by Monte Carlo simulations. Most simulations of such detectors simplify the setup by only taking the conversion layer into account neglecting behind. The Monte Carlo code MCNPX has been used to simulate the complete interaction and subsequent charge transport of x-ray radiation. This has allowed the analysis of charge sharing between pixel elements as an important limited factor of digital x-ray imaging system. The parameters are determined by lateral distribution of x-ray photons and x-ray induced electrons. The primary purpose of this study was to develop a design tool for the evaluation of geometry factor in the phosphor coupled optical imaging detector. In order to evaluate the spatial resolution for different phosphor material, phosphor geometry we have developed a simulation code. The developed code calculates the energy absorption and spatial distribution based on both the signal from the scintillating layer and the signal from direct detection of x-ray in the detector. We show that internal scattering contributes to the so-called spatial resolution drop of the image detector. Results from the simulation of spatial distribution in a phosphor pixel detector are presented. The spatial resolution can be increased by optimizing pixel size and phosphor thickness.

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The Cooling Effect of Fog Cooling System as Affected by Air Exchange Rate in Natural Ventilation Greenhouse (자연환기 온실의 환기회수에 따른 포그냉방시스템의 냉방효과)

  • 김문기;김기성;권혁진
    • Journal of Bio-Environment Control
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    • v.10 no.1
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    • pp.10-14
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    • 2001
  • The cooling effect of a fog cooling system has a close relationship to air flow and relative humidity in the greenhouse. From the VETH chart for cooling design, a cooling efficiency can be improved by means of increasing the air exchange rate and the amount of sprayed water. In the no shading experimental greenhouse by time control, when average air exchange rate was 0.77 times.min$^{-1}$ and spray water amount was 2,009g, inside temperature of the greenhouse was 31$^{\circ}C$ that was almost close to outside temperature and cooling efficiency was 82%. When average air exchange rate was close to temperature of the greenhouse that was no cooling and 70% shading greenhouse environment. When average air exchange rate was 2.59times.min$^{-1}$ , spray water amount was 2,009g and shading rate was 70%, inside relative humidity of the greenhouse was increased was 2,009 g and shading rate was 70%, inside relative humidity of the greenhouse was increased, but temperature was not decreased. When average air exchange rate was 2.33 times.min$^{-1}$ and spray water amount was 2,009g, inside temperature was 31.4 and at that time maximum wind speed at the air inlet of greenhouse was 1.9m.s$^{-1}$ . Since time controller sprayed amount of constant water at a given interval, some of sprayed water remained not to be evaporated, which increased relative humidity and decreased cooling efficiency. Because the shading screen prevented air flow in the greenhouse, it also caused the evaporation efficiency to be decreased. In order to increase cooling efficiency, it was necessary to study on controling by relative humidity and air circulation in the greenhouse.

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A Study on the Design of Non-working Days Process by Analyzing Business Information (업무정보 분석을 통한 작업불능일 산정 프로세스 설계에 관한 연구)

  • Kim, Beop-su;Bang, Hong-soon;Choi, Byung-Ju;Kim, Ok-kyue
    • Korean Journal of Construction Engineering and Management
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    • v.19 no.5
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    • pp.61-69
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    • 2018
  • Construction projects consist of long-term on-site production, and most disciplines are featured by outdoor works. Therefore, when a process plan is established, non-working days are calculated and reflected in a process schedule to comply with the planned construction period. However, necessary information and working methods are different in the course of the work, so the method of calculation varies depending on persons even for the same site, and the result is also very different. Therefore, scientific and quantitative understanding of business information is needed. This study reconstructed non-working day estimation process by collecting and organizing the information necessary for non-working day estimation, and designed the demonstration screen based on the reconstructed process and verified through expert interview at each stage. As a result, it showed about 69% reduction of work time and reliability of 92% work information matrix, and 80% of the experts evaluated the systemization of the relevant work. This study is expected to improve the understanding of work and increase the efficiency of work performance, and the study on systemization in the future should be continued.

The Effects of Active Movement Myofascial Decompression Therapy and Static Myofascial Decompression Therapy on Range of Motion, Muscle Strength, Functional Movement in Young Adults. (젊은 성인에서 능동 움직임을 결합한 근막감압치료 적용과 정적 적용이 관절가동범위, 근력, 기능적 움직임에 미치는 영향)

  • Lee, Jee-Hyun;Kim, Tae-Hyeon;Kang, Si-Yun;Kum, Do-Gun;Lee, Sung-Yeon;Do, Kwang-Sun;Kim, Chang-Sook;Bae, Ju-Han;Park, Jun-Hyuck;Kim, Jae-Eun
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.3
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    • pp.165-173
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    • 2021
  • Purpose : Myofascial decompression is frequently mentioned as a method applied to cupping. The purpose of this study is to evaluate and compare active range of motion (AROM), muscle strength, and functional movement by applying myofascial decompression to the hamstrings. Methods : This study evaluated AROM, muscle strength, and functional movement by applying active movement myofascial decompression and static myofascial decompression to the dominant leg, respectively, in a crossover design conducted with normal adults (n=21) in their average 20s enrolled at G University in G city, Gyeongsangbuk-do. Active movement myofascial decompression was implemented for five minutes at a rate of 100 bpm to make the beats in flexion and extension respectively. Static myofascial decompression was only performed for five minutes while at rest. All of these interventions were performed at a cupping depth of two mm. After a one-week washout period, static was applied again to compare the same dependent variables. Results : Regarding AROM and muscle strength, both groups showed significant differences in the before and after results (p<.05). However, in the Functional Reach Aspect and Single Leg Hop test, the active movement myofascial decompression group showed better results. There was no statistical difference between the Active movement myofascial decompression group and Static myofascial decompression group in any dependent variable (p<.05). Conclusion : As a result of this experiment, both active movement myofascial decompression and static myofascial decompression had a positive effect on dependent variable. Therefore this study is meaningful in that it is easier and simpler to see the effect on flexibility, muscle strength, and functional movement just by implementing movement myofascial decompression.