• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.10
• /
• pp.4583-4586
• /
• 2016

Background: Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin's lymphoma, with a pathognomonic chromosomal translocation t (11;14). Prognosis is uniformly dismal but there is a paucity of information on MCL from India. Materials and methods: We retrospectively analysed clinicopathological information on all treated patients with MCL at our centre. STATA 14.0 was used for analysis. Survival was assessed by Kaplan-Meier analysis and the Cox's proportional hazards method. Statistical significance was defined as a P value of < 0.05. Results: Fifty-one patients with MCL were reviewed. The median age at presentation was 57.0 years. Extranodal involvement was seen in 39.0 (74.0%) while bone marrow positivity at presentation was found in 27.0 (54.0%). Initial treatment was chemotherapy with or without rituximab. Patients receiving rituximab-based therapy (n = 24) had 5-year progression-free survival (PFS) of 21.0 (88.0%), compared with 14.0 (61.0%) for those not receiving rituximab (n = 23, P = 0.036). Twenty-three patients were alive with a median follow-up of 20.7 months (range 2.5-89.2). PFS at 1 and 2 years was 51.0% and 27.0%, and overall survival (OS) 78.0% and 72.0%, respectively. Use of more than 2.0 lines of therapy, use of bendamustine-rituximab, and high TLC (>10,000.0/cu.mm) significantly affected PFS. Conclusions: In our experience, MCL patients from north India have an early age at presentation. When treated with regimens including rituximab results in an improved response rate and PFS. This study provided comprehensive insights into the treatment of MCL in a developing country.

• Journal of the Korean Society of Earth Science Education
• /
• v.4 no.1
• /
• pp.32-42
• /
• 2011

The purpose of this study is to provide meaningful basic materials for organizing a science curriculum in future by analyzing the status and changes of contents about astronomical phenomena in textbooks according to the changes of the science curriculum of elementary school. A main target of analysis is science textbooks of elementary school in curriculums from 1st to 7th. For the analysis, the analytic frame based on contents in astronomy textbooks of teachers colleges and colleges of education was used. The result of the analysis is as in the following. First, astronomy accounted for average about 7% of all pages of textbooks in all of science curriculums. The 1st educational curriculum had the most learning quantity of 10.40%, and the 6th curriculum had the least quantity of 4.39%. These results show that astronomy was not a small part and was considered important in each science curriculum of elementary school considering that earth science accounted for 17-26% of all pages in elementary school science curriculum. Second, the things that have been dealt with in common in all science curriculums from 1st to 7th of elementary school are the shape of the earth, the rotation and the revolution of the earth, the occurrence of the seasons, the apparent motion of the sun, the status and motion of the moon, the movement of a star, the brightness and distance of a star, constellations, the sun, planets and others. These contents are expected to be dealt with continuously as basic contents to organize astronomy regardless of the changes of curriculum. Third, in science curriculum of elementary school, astronomical phenomena based on life experiences regarding the earth, the moon and the sun are mainly dealt with in the first and the second grade. Contents requiring principles-understanding and research are dealt with in the fifth and sixth grade. These results show that elementary school science curriculum dealing with astronomy reflects the developmental stages of students and considers principle of learning possibility.

• International Journal of Computer Science & Network Security
• /
• v.21 no.12
• /
• pp.35-40
• /
• 2021

The study aimed to realize one of the basic requirements for designing and building the integrated automated system for scientific research at Northern Border University, which includes the establishment of an automated interconnected system to manage all academic and financial operations of scientific research. From receiving the budget of the funded research courses, then the regular financial regulation of all the research team's rewards, the cost of publishing, translation and equipment, then receiving the research plans and linking them financially, preparing the total and detailed financial value for all stages, then financial disbursement operations, financial closure of research when published, and preparing financial reports The research team used the analytical approach to build the main and subsidiary requirements for designing the financial system, and the study concluded that all the elements required for the stages of financial management for scientific research at Northern Border University can be met based on sufficient by sequencing these processes and how they are sequenced as e It is designed in the research study.

• Journal of the Korean Wood Science and Technology
• /
• v.51 no.4
• /
• pp.253-269
• /
• 2023

Oriented strand board (OSB) distributed in Korea was collected, and its mechanical properties were investigated according to the International Organization for Standardization (ISO), Japanese Industrial Standards, and Korean Design Standard. Ten types of OSBs were collected, including six types for walls and others for floors. The thickness swelling, moisture content, and density of each product satisfied the ISO standards. All products showed lower formaldehyde emission values than those of the SE0 grade. The internal bonding strengths of all products, except products B, H, and I, met the ISO standards. However, products A, B, C, F, and H did not satisfy the thickness swelling standard of the load-bearing OSB for use in dry conditions. Products D and G showed heavy duty load-bearing OSB for use in humid conditions in terms of internal bonding and bending strength after boiling. In the nail head pull-through force and lateral nail resistance tests, all products met the standards. In terms of the structural bending performance (four points), the six types of OSBs for walls satisfied the standard for bending strength and modulus of elasticity. All the products for flooring met the standard for bending strength but, except for product G, the products did not meet the standard for modulus of elasticity. Although the results of this study cannot represent the performance of all imported OSBs, considering the above results, the water resistance performance of seven types of OSB products did not meet the standard, and 10 types of products did not match the labeling grades.

• Proceedings of the Korean Society of Broadcast Engineers Conference
• /
• 1997.06a
• /
• pp.75-81
• /
• 1997

A new DTPP (Desk-Top Program Production) system has been developed that enables multiple program producers (directors) working at different locations to collaborate over a computer network and prepare a single program for broadcasting. In this system, information is shared among users by exchanging data edited on non-linear editing terminals in program post-production work over a network in real time. In short, the new DTPP system provides a collaborative work space for producing TV programs. The system does not make use of a special server for collaborative work but rather multiple interconnected editing terminals having the same functions. In this configuration, data at a terminal which has just been edited by some operation is forwarded to all other connected terminals for updating. This form of information sharing, however, requires that some sort of data synchronizing method be established since multiple terminals are operating on the same data simultaneously. We therefore adopt a method whereby the system synchronizes the clocks on each terminal at the time of connection and sends an operation time stamp together with edited data. This enables most recently modified data to be identified and all information on all terminals to be updated appropriately. This paper provides an overview of this new collaborative DTPP system and describes the techniques for exchanging edited data and synchronizing data.

• Korean Journal of Optics and Photonics
• /
• v.14 no.5
• /
• pp.530-534
• /
• 2003

A novel all-optical NOR gate is proposed and demonstrated for the first time by use of gain saturation in a semiconductor optical amplifier (SOA). It is operated by the nonlinearity of the SOA gain. Hence, to obtain sufficient gain saturation of the SOA, pump signals are amplified by an Er-doped fiber amplifier at the input of the SOA. The operation characteristics of the all-optical NOR gate are successfully measured at 10 Gbit/s.

• Journal of The Korean Association For Science Education
• /
• v.14 no.2
• /
• pp.214-224
• /
• 1994

The Ministry of Education established the plan to adopt a new college enterance examination system, so called Scholastic Ability Test for college, from 1994. The National Board of Educational Evaluation had carried out 7 experimental trials for the new examination system. Eventhough, the governmental officials advertised the purpose and characteristics of the new examination system, many students and parents did not understand the essential point very well. In this study the researcher tried to analyze the 7 trial examination items and the first Scholastic Ability Test for college carried out 1993. In this study, the researcher tried to find out all the items appeared in the 7 trials. In the analysis, all the individual items from the 1st trial to the 7th trial were used. The research results showed that the items were evenly distributed in all the four areas(Physics, Chemistry, Biology and Earth Science) of science content; however, they were heavily concentrated on data or information analysis categoris in the inquiry domain. In the domain of context, laboratory context was the major item context. The scores were also analyzed. The results showed that no significant difference between male and female students. However, science track students showed higher achievement scores than the non-science track student. The examination result showed high correlation with the tests routinely have carried out in schools. The over all analysis showed the new examination system showed very different characteristics to the conventional tests. Therefore, for the student to get successful result in the Scholastic Ability Test, they should change the way of study. They should try to understand scientific concepts rather than to memorize them. They should invest their time to carry out real experiments rather than to focus on the princples and laws of science. One of the most important thing would be for the student to apply what they learned to real life situations.

• Proceedings of the Korean Operations and Management Science Society Conference
• /
• 1998.10a
• /
• pp.282-285
• /
• 1998

The purpose of this study is to present a method for determining the k most vital arcs in the maximum flow problem using a heuristic method. Generally, the problem which determine the k most vital arcs in maximum flow problem has known as NP-hard. Therefore, in this study we propose a method for determining all the k most vital arcs in maximum flow problem using a genetic algorithm. The proposed algorithm found all alternatives within shorter time than other heuristic methods. The method presented in this study can determine all the alternatives when there exists other alternative solutions.

• Kyungpook Mathematical Journal
• /
• v.27 no.1
• /
• pp.35-41
• /
• 1987

Consider the system (i) x'=Ax. Let ${\Phi}$ be its fundamental matrix solution. If there is w>0 such that A(t+w)-A(t) commutes with ${\Phi}$ for all t, then we call this system a "generalized" Floquet system or a "G. F. system". We show that $A(t+w)-A(t)=B_1$=constant if and only if $A(t)=C+B_1t/w+Q(t)$, Q is periodic of period w>0. For this A(t) We prove that if all eigenvalues of $B_1$ have negative real parts, then the origin is asumptotically stable. We find a growth condition for a continuous D(t) which guarantees that all solutions of z'=[A(t)+D(t)]z are bounded if all solutions of the G. F. system (i) are bounded. Combining the foregoing results yield a class of perturbed G. F. operators all of whose solutions are bounded.

• Preventive Nutrition and Food Science
• /
• v.1 no.1
• /
• pp.30-36
• /
• 1996

This study was conducted to investigate the changes in chemical, microbial, sensory characteristics and volatile flavor components of wooung(burdock, Arctium lappa, L) kimchi during fermentation at 15$^{\circ}C$, Three types(A, B, C) of wooung kimchi were prepared. Sample A was prepared with basic ingredients, in the other hand, sample B was prepared with all sorts of ingredients. These samples were mixed after salting the sliced burdock with 4% brine for 30min. Sample C was prepared mixing with all sorts of ingredients after blanching the sliced burdock with 2% vinegar solution. pH decreased slowly until 3 day, and then decreased rapidly for 4~7 days in all samples. Total acidity increased gradually in all samples. The changes of pH and total acidity were the sample C and were the greatest in sample B. The reducing sugar contents decreased slowly until 7 day, and decreased rapidly for 8~14 days in sample A and B, and at 10 day in sample C, respectively. The numbers of lactic acid bacteria and total bacteria of sample B were much greater than those of other sample. In sensory evaluation, sample B exhibited the best scores and sample C showed the worst scores in all characteristics. The major volatile components in wooung kimchi were identified as ethanol, hexanal, 2-hexenal, disulfide dl- 2-prophenyl, zingiberene and $\beta$-sesquiphellandrene. The relative amounts of hexanal, 1-hexanol and ethanol were decreased, while the relative amounts of acetic acid ethyl ester, 3-htdroxy-2-butanone and acetis acid were increased gradually during fermentation.