• Title/Summary/Keyword: Science and engineering

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Construction and Service of a Web-based Simulation software management system for the Computational Science and Engineering (계산과학공학 분야를 위한 웹 기반 시뮬레이션 소프트웨어 관리 시스템 구축 및 서비스)

  • Jeon, Inho;Kwon, Yejin;Ma, Jin;Lee, Sik;Cho, Kum Won;Seo, Jerry
    • Journal of Internet Computing and Services
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    • v.18 no.4
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    • pp.99-108
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    • 2017
  • Open Science is evolving not only to share research results, but also to open the research process. We are developing the EDISON platform for the spread of open science in computational science and engineering. The EDISON platform provides online simulation services developed by computational science and engineering researchers. It also provides an environment for sharing source code, data, and related research publications. An effective simulation software registration management system is required for successful service on the EDISON platform. In this paper, we proposes a simulation software management system to provide online simulation service through EDISON platform. The proposed system allows the developer to register the simulation software on the EDISON platform without administrator intervention and effectively build a web-based simulation environment.

Regulatory Roles of Chrysanthemum zawadskii Roots in Nuclear Factor E2-related Factor 2/Antioxidant Response Element Pathway

  • Kang, Hye-Sook;Park, Min-Ji;Jin, Kyong-Suk;Kim, Young-Hun;Jun, Mi-Ra;Lim, Ho-Jin;Jo, Wan-Kuen;Kim, Jong-Sang;Jeong, Woo-Sik
    • Food Science and Biotechnology
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    • v.17 no.2
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    • pp.367-372
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    • 2008
  • Cellular protection against carcinogens could be achieved by the induction of phase 2 detoxifying and antioxidant enzymes such as glutathione S-transferase (GST), NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO1). Nuclear transcription factor E2-related factor 2 (Nrf2) binds to antioxidant response element (ARE) in the promoter region of these genes and the resulting transactivation occurs. In the present study the effect of gujeolcho (Chrysanthemum zawadskii) roots on the Nrf2-ARE pathway were investigated. C. zawadskii root extract was fractionated with a series of organic solvents and their ability to induce Nrf2-ARE pathway was examined. We separated the most potent dichloromethane (DCM) fraction into 12 sub-fractions and found several sub-fractions with strong effects on the Nrf2-ARE pathway. Fraction 4 strongly induced the ARE-reporter gene activity as well as Nrf2 expression. Sitosterol was isolated as a major compound in fraction 4 although its activity was not as potent as its mother fraction. These results indicate that C. zawadskii roots might be used as a potential natural chemopreventive source.

Luminescent characteristics of a blue-emitting $CaAl_2Si_2O_8:Eu^{2+}$ phosphor and the effect of boron ion substitution

  • Kwon, Byoung-Hwa;Vaidyanathan, Sivakumar;Li, Hui;Jang, Ho-Seoung;Yoo, Hyoung-Sun;Jeon, Duk-Young
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.578-580
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    • 2008
  • Blue-emitting $CaAl_2Si_2O_8:Eu^{2+}(CAS:Eu^{2+})$ phosphor, prepared by solid-state reaction, is described in this paper. We researched the effect of boron ion substitution in the host materials. The phase and luminescent properties were investigated using the powder X-ray diffraction(XRD) and photoluminescence(PL) spectra.

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