• Korean Journal of Clinical Pharmacy
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• v.31 no.1
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• pp.53-60
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• 2021

Objective: To gather the opinions of hands-on workers for successful introduction of the Development Safety Update Report (DSUR) according to a five-year comprehensive plan for clinical trial development [Ministry of Food and Drug Safety, 2019]. Methods: We conducted a survey on considerations that industry stakeholders may have related to the enforcement of the DSUR. A questionnaire was distributed among pharmacovigilance specialists from 13 pharmaceutical companies in South Korea on June 4, 2020. The questionnaire comprised two sections: 1) current status of the Drug Safety Data Management System and 2) considerations on the implementation and management of the DSUR. Results: All respondents have agreed the introduction of DSUR is inevitable for regulatory harmonization and safety of trial subject. However, most respondents (85%) felt concern about additional workload with DSUR implementation. They answered that format and operation system of DSUR should be harmonized with those of international standards and authorities need to minimize double burden due to related report. Conclusion: All respondents asserted that domestic DSUR should be harmonized with International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) E2F guidelines. Respondents from global companies also suggested regulatory authorities allow DSUR written in English to replace Korean version considering their deadline for submission. Moreover, every respondent agreed regulatory authorities need delicate effort when implementing mandatory submission of DSUR to ensure that even small pharmaceutical companies with no experience in DSUR can comply with the system.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.9-22
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• 2023

As a famous herbal medicine in China and Asia, ginseng (Panax ginseng C. A. Meyer) is also known as the "King of All Herbs" and has long been used in medicine and healthcare. In addition to the obvious biological activities of ginsenosides, ginseng polysaccharides (GPs) exhibit excellent antitumor, antioxidant stress, and immunomodulatory effects. In particular, GPs can exert an antitumor effect and is a potential immunomodulator. However, due to the complexity and diversity in the structures and components of GPs, their specific physicochemical properties, and underlying mechanisms remain unclear. In this article, we have summarized the factors influencing the antitumor activity of GPs and their mechanism of action, including the stimulation of the immune system, regulation of the gut microbiota, and direct action on tumor cells

• Nuclear Engineering and Technology
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• v.51 no.4
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• pp.963-967
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• 2019

Accurate measurement of the reactivity worth of safety rods is very important for the safe reactor operation, in normal and emergency conditions. In this paper, the reactivity worth of safety rods in Heavy Water Zero Power Reactor (HWZPR) in the new lattice pitch is measured by advanced source jerk method. The average of the results related to two different detectors is equal to 29.88 mk. In order to verify the result, this parameter was compared to the previously measured value by subcritical to critical approach. Different experiment results are finally compared with corresponding calculated result. Difference between the average experimental and calculated results is equal to 2.2%.

• Journal of Korean Academy of Nursing
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• v.44 no.2
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• pp.119-128
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• 2014

Purpose: This study is an examination of the paths in which the primary factors of anxiety, impulsiveness, knowledge of life safety practice, attitudes towards life safety practice, interpersonal support, and self-efficacy from Pender's Health Promotion Model influence the practice of life safety behavior in school-age children. Methods: The sample consisted of 489 5th and 6th grade students recruited from five elementary schools in Seoul City and four provinces, South Korea. Data were analyzed using descriptive statistics, correlations, factor analysis, and structural equation modeling. Results: Attitudes towards life safety practice, interpersonal support, self-efficacy and impulsiveness directly influenced practice of life safety behavior. Anxiety did not have a direct influence on practice of life safety behavior, but indirectly affected it. In this modified model, 52.0% of the practice of life safety behavior was explained by the primary factors. Conclusion: To facilitate the practice life safety behaviors in late childhood, a positive attitude towards life safety needs to be developed along with decreasing impulsiveness and enhancing self-efficacy.

• Korean Journal of Hazardous Materials
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• v.6 no.2
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• pp.30-38
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• 2018

This study analyzed the gender factors and priorities that are on the basis for establishing the school safety education policy according to the times when the demand for customized education is increasing. AHP analysis method was used in the paper for systematic and hierarchical analysis. We had checked a safety education specialist group to identify the priorities of important factors to improve the efficiency of analysis. The male group first considered the change of the beneficiary by policy guidelines, and the female group regarded the change of interest and public opinion as important. This has studied the difference in approach between the two groups, although the key elements of the detailed policy are the same. This study suggests that school safety education is effective in improving effective gender safety education response capacity and ensuring substantive policy sustainability.

• Journal of the Korea Safety Management & Science
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• v.25 no.4
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• pp.79-85
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• 2023

This study aims to verify the impact of a metaverse-based safety education program on the fire safety awareness of elementary school students. Utilizing the National Fire Agency's 119 metaverse program, an educational program was implemented for two months, and the experimental group was examined using paired-sample t-tests, while comparisons with the control group were made using independent-sample t-tests. The results revealed statistically significant differences between the experimental and control groups in the area of fire prevention. Although no statistically significant differences were observed over time within each group, the overall average scores for the entire class improved across all areas. Based on these findings, the effectiveness of metaverse-based safety education is suggested; however, a significant difference compared to traditional education was not detected. The study concludes by exploring implications for considerations in the implementation of metaverse safety education in the future.

• International Journal of Highway Engineering
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• v.19 no.2
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• pp.167-174
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• 2017

PURPOSES: This study aims to analyze the impact of the implementation of a school zone traffic safety improvement project on the number of accidents involving children in these zones. METHODS : To analyze the correlation between school zone traffic safety features of roads in the zone and the number of accidents involving children, we developed an occurrence probability model of traffic accidents involving children by using a binary logistic regression model with SPSS 23.0 software. Two separate models were developed for two zones: interior block and arterial road. RESULTS :The model depicted that in the case of the interior block, shorter sidewalk width, speed bump, and an elevated crosswalk were key factors affecting the occurrence of accidents involving children. In the case of arterial roads exceeding a width of 12 m, the speed limit, roadside barriers, and red paving of road surfaces were found to be the key factors. CONCLUSIONS:The results of this study can serve as the elementary research data to help improve the effectiveness of school zone traffic safety improvement projects and school zone road repair projects in future.

• Journal of the Korean Society of School Health
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• v.22 no.1
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• pp.145-153
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• 2009

International Safe School(ISS) model has focused as a public health approach to develop safety intervention to address injury problems in school setting. It needs school members involvement in partnership with community resources to address the needs for school based injury prevention and safety promotion. The characteristics and principles of ISS model discussed in this paper emphasizes participation, capacity and partnership building, evidence based process, and so on. A 7 criteria is introduced as ISS implementation strategy. Multilevel and multi-facet approaches are valuable on ISS as well as process evaluation. For the application of ISS model in Korea, finding evidence, building public health partnership between school and other public or private resources in community are necessary conditions for succesful ISS for health promotion in school setting.

• Safety and Health at Work
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• v.7 no.1
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• pp.12-17
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• 2016

Background: The mining industry is considered as one of the most dangerous and hazardous industries and the need for effective and efficient occupational health and safety management is critical to safeguard workers and the industry. Despite the dangers and hazards present in the mining industry, only few studies have focused on how occupational health and safety and turnover intentions in the mines. Method: The study suing a cross-sectional survey design collected quantitative data from the 255 mine workers that were conveniently sampled from the Ghanaian mining industry. The data collection tools were standardized questionnaires that measured occupational health and safety management and turnover intentions. These scales were also pretested before their usage in actual data collection. Results: The correlation coefficient showed that a negative relationship existed between dimensions of occupational health and safety management and turnover intention; safety leadership (r = -0.33, p < 0.01); supervision (r = -0.26, p < 0.01); safety facilities and equipment (r = -0.32, p < 0.01); safety procedure (r = -0.27, p < 0.01). Among these dimensions, safety leadership and safety facility were significant predictors of turnover intention, (${\beta}=-0.28$, p < 0.01) and (${\beta}=-0.24$, p < 0.01) respectively. The study also found that turnover intention of employees is heavily influenced by the commitment of safety leadership in ensuring the effective formulation of policies and supervision of occupational health and safety at the workplace. Conclusion: The present study demonstrates that safety leadership is crucial in the administration of occupational health and safety and reducing turnover intention in organizations.

• Proceedings of the Safety Management and Science Conference
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• 2011.11a
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• pp.619-637
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• 2011

The development of society and the desire for a happy life for the safety of the public's interest in higher things of the increased body, Bain safety awareness and safety of repeated disasters without action to prevent the spread will have no choice but to tough it will also harm. Safety education training from an early age desperately needed for safety's why. Elementary Middle High School students' characteristics and level of safety for your knowledge, skills, attitudes and habits in order to train to teach in any manner whatsoever any information about the study will assess the need.