• Maxillofacial Plastic and Reconstructive Surgery
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• 제21권1호
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• pp.1-12
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• 1999

The purpose of this study was to evaluate the healing process of the calvarial defect filled with hydroxylapatite(HA) and $TGF-{\beta}$ in Rat. 72 Sprague-Dawly rats were divided into 3 groups, control and two experimental groups. Bony defect were artificially prepared in the calvaria of all 72 rats and followed by implantation of HA (experimental group of 24 rats) and HA+$TGF-{\beta}$(another experimental group of 24 rats) into the defects. Sequential sacrifice was performed at 1, 2, 4, 6, 8, 12 weeks of experiment. Obtained specimen was stained with Hematoxylin and Eosin, Masson's Trichrome and Immunohistochemistry. The results were as follows, 1. Granulation tissue was prominent on control group in 1 and 2 weeks. Bony defects were filled with dense fibrous tissue through the whole experimental period and osteoinduction could not be observed in all groups. 2. Inflammatory cell infiltration was prominent on control group in 1 and 2 weeks and osteoclastic activity was high in HA implanted experimental group at 1 and 2 weeks. 3. Inflammatory cell infiltration was less and maturation of fibrous tissue could be found on HA+$TGF-{\beta}$ implanted experimental group at 1 and 2 weeks. 4. Osteoconduction activity was high in HA+$TGF-{\beta}$ implanted experimental group at 2 and 4 weeks but there was no difference after 6 weeks among 3 groups. 5. In grafted site of HA+$TGF-{\beta}$ implanted group, osteonectin expression was slightly increased from 1 week to 6 weeks. In the host site, it was increased from 1 to 4weeks. 6. In grafted site of HA+$TGF-{\beta}$ implanted group, osteocalcin expression was high at 4 weeks. In the host site, we could find the difference among 3 groups. From above results, the HA with mixture of $TGF-{\beta}$ has the potentiality of promoting bone formation in the bony defect area in the rat.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권6호
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• pp.273-279
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• 2014

Purpose: This study assessed the association between eye symptoms (enophthalmos or diplopia) and site of damage, volume, deviated inferior rectus muscle (IRM) and type of fracture with computed tomography (CT). The intent is to anticipate the prognosis of orbital trauma at initial diagnosis. Methods: Forty-five patients were diagnosed with fractures of the inferior wall of one orbit. Fracture area, volume of displaced tissue, deviated IRM, and type of fracture were evaluated from coronal CT by one investigator. The association of those variables with the occurrence of eye symptoms (diplopia and enophthalmos) was assessed. Results: Of 45 patients, 27 were symptom-free (Group A) and 18 had symptoms (Group B) of enophthalmos and/or diplopia. In Group B, 12 had diplopia, one was enophthalmos, and five had both. By CT measurement, group A mean area was $192.6mm^2$ and the mean volume was $673.2mm^3$. Group B area was $316.2mm^2$ and volume was $1,710.6mm^3$. The volume was more influential on symptom occurrence. Each patient was categorized into four grades depending on the location of IRM. Symptom occurrence and higher grade were associated. Twenty-six patients had trap-door fracture (one side, attached to the fracture), and 19 had punched-out fracture (both sides detached). The punched-out fracture was more strongly associated with symptoms and had statistically significantly higher area and volume. Conclusion: In orbital trauma, measurement of fracture area and volume, evaluation of the deviated IRM and classification of the fracture type by coronal CT can effectively predict prognosis and surgical indication.

• 한국조경학회지
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• 제29권6호
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• pp.50-61
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• 2002

As recognition and polices for plans to preserve natural resources and to develop environment-friendly space in school education is developed, not only organization of curriculums related to these is required but also facilities for the education are indispensable. Therefore, this study tries to suggest several standards on matters including kinds and scale of facilities and the introduction of species by facilities required for outdoor teaming spaces for environmental education in the elementary school system. The methods of this study include researching various records related to environmental education in elementary school, researching the present condition of outdoor learning space installed and operating in the existing schools by making an on-the-spot survey, and analyzing appearance frequencies of plants and animals displayed in the text. In addition, the actual conditions of the facility use and management were investigate through a questionnaire, We chose and diagrammed a model of the installed facilities by putting the results together. For analyses the investigated eight schools, were categorized as ‘facilities-arranged type’or ‘connection type with ecological park’. The first type distributed and arranged facilities, including meteorological observatory, rocky park, experience-learning area, ecological pond, animal-breeding farm and field-leaning area into appropriate locations according to the site conditions of the school while the second type created a natural learning place by integrating several facilities and arranging areas such as an animal-breeding farm and experience-learning area into appropriate sites. In this study, essential facilities for outdoor learning are classified into ecological park, experience-loaming area, field loaming area, and for natural learning, meteorological observatory, animal-breeding farm, and greenhouse.

• 대한원격탐사학회지
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• 제34권5호
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• pp.763-775
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• 2018

본 연구에서는 지리정보시스템(GIS)자료와 전산유체역학(CFD) 모델을 사용하여 방풍벽이 건물 밀집 지역에 위치한 공사 지역에서 발생하는 대기오염물질의 확산에 미치는 영향에 대해 분석하였다. 부산 ASOS에서 10년 동안 관측된 풍속을 평균하여 기준 고도(지상 10 m)에서의 유입류로 사용하였다. 수치 실험은 방풍벽 건설 전과 5 m 및 10 m 높이의 방풍벽을 건설한 후에 대해 16 방위 풍향을 유입류로 진행하였고, 부산 ASOS에서 높은 빈도를 나타낸 북동풍과 남남서풍에 대한 상세 흐름을 분석하였다. 북동풍에서는 북동쪽에서 불어오는 흐름에 의해 비산 먼지가 확산되어 공사 지역 내부에 위치한 감천초등학교에서 대기오염물질 농도가 높게 나타났다. 5 m 높이의 방풍벽을 설치했을 때는 방풍벽 설치 전에 비해 풍속이 조금 감소했고 비산 먼지의 확산이 줄었다. 10 m 높이의 방풍벽을 설치한 경우, 초등학교에서의 평균 대기오염물질 농도는 37% 감소하였다. 남남서풍 유입류에서는 지형과 건물의 영향으로 공사 지역에서 복잡한 흐름 패턴이 형성되었다. 남쪽 공사 지역에서는 비산 먼지가 정체되어 농도가 높게 나타난 반면, 초등학교는 북풍의 흐름에 의해 대기오염물질 농도가 높게 나타났다. 방풍벽 건설 후에는 공사 지역 내부에서 풍속이 감소하면서 공사장 내부 농도는 높아졌지만, 초등학교에서의 농도는 감소했다.

• Archives of Plastic Surgery
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• 제35권6호
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• pp.698-702
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• 2008

Purpose: Basal cell carcinoma is one of the most common cancers in the western population and the annual incidence rate is still on an increasing course. In Asian countries such as Korea, the incidence of basal cell carcinoma is reported to be remarkably low but is estimated to be in a steep increase nowadays. This study was to analyze the recent clinical trends of basal cell carcinoma in Korea by reviewing a single institution's experience. Methods: Throughout an 11-year period, the surgical excision of 143 cases of basal cell carcinoma was performed in our department. General data of these cases such as the primary site of cancer, age and sex of the patient, operative methods, recurrence rate were reviewed retrospectively. Results: Among the 143 patients included in this study, 82 patients were men and 61 patients were women. The ages ranged from 27 to 89 years with a mean age of 64.0 years. The head and neck region was the most frequently involved primary site for the cancer as 95.1% of the total cases occurred in this area. Especially the nose and perinasal area were the most frequent region, which was followed by the periorbital area, cheek, and perioral area. During this study period, 9 cases showed recurrence of the cancer as the overall recurrence rate was 6.3%. Conclusion: Gradual increase in the incidence of basal cell carcinoma was demonstrated in this study. Basal cell carcinoma showed high incidence in the old-age population as 68.5% of the total patients were more than 60 years of age. High recurrence rate was noted in the nasal region especially after local flap reconstruction. A more cautious approach is to be required when handing such high risk lesions. Multiple factors such as extended life span, increased outdoor leisure activity and exposure to sunlight, higher accessibility to medical services and increased understanding of the public about skin cancer are assumed to be the main reasons for this increase of basal cell carcinoma.

• Journal of Periodontal and Implant Science
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• 제36권2호
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• pp.305-318
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• 2006

This study was performed to evaluate the effect on the formation of keratinized attached gingiva when free gingival graft with strip technique was used. After the partial thickness flap was prepared, it was positioned apically more than 7mm using mucoperiosteal suture. At the donor site, strip was achieved with 2mm width, less than 1mm thickness, (mesiodistal teeth length + 6)$^{\ast}$2 mm length. Then, it was divided into 2 same pieces and located at the recipient bed apico-coronally with more or less 3mm interval. Follow-up check was made at 1,2,4,8,12 weeks after the operation. The results of this study were as follows : 1. The inter-strip space was mostly filled with keratinized attached gingiva. 2. The contraction of the graft was nigligible, and 92% of planned area was filled with keratinized attached gingiva. 3. The inconvenience of the patients at donor site was minimal. 4. The width of the strip was widened. In conclusion, free gingival graft using strip technique is useful to achieve the keratinized attached gingiva maximally with free gingival graft minimally and to minimize the inconvenience of donor palatal site of the patients.

• Bulletin of the Korean Chemical Society
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• 제34권6호
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• pp.1663-1667
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• 2013

Neointimal hyperplasia causes vascular access dysfunction in hemodialysis patients with synthetic arteriovenous (AV) grafts. Several studies have reported that paclitaxel- or sirolimus-eluting AV grafts inhibit neointimal hyperplasia and display lower rates of stenosis compared with control grafts. However, there have been few comparative studies of the efficacy of paclitaxel- and sirolimus-eluting grafts. We compared the neointimal hyperplasia of paclitaxel- and sirolimus-eluting grafts. AV grafts were implanted laterally between the common carotid artery and the external jugular vein in 12 female Landrace pigs. The animals were sacrificed six weeks after surgery. The neointimal hyperplasia at the anastomosis sites of the grafts was quantified using the ratio of the intragraft hyperplasia to the graft area (H/G ratio) at the graft-vessel interface. The area of intimal hyperplasia at the venous (paclitaxel 1.06 [0.72-1.56] vs sirolimus 2.40 [1.72-3.0] $mm^2$, P = 0.04) and arterial anastomosis sites (paclitaxel 0.93 [0.57-1.48] vs sirolimus 2.40 [1.72-3.0] $mm^2$, P = 0.04) was significantly different between the two groups. However, the H/G ratios for the venous anastomosis site (paclitaxel 0.25 (0.17-0.38) vs sirolimus 0.38 (0.2-0.66), P = 0.4) and the arterial anastomosis site (paclitaxel 0.19 (0.08-0.39) vs sirolimus 0.41 (0.34-0.50), P = 0.1) did not differ significantly between the groups. In conclusion, there was no significant difference in the inhibition of neointimal hyperplasia by sirolimus- and paclitaxel-eluting AV grafts.

• 한국생활과학회지
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• 제9권3호
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• pp.297-315
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• 2000

The purpose of this study is to provide the basic data for the leisure space planning desirable for adolescents through survey on their using leisure space. Four hundred sixty-six middle and high school students living in Chongju city, Gwesan-gun and Eumsung-gun responded the first basic questionnaire and 160 students among them answered again the second questionnaire for more information on the site of leisure space they want. Frequency, percentage, $x^2-test$ and Multi-Dimensional Scale were methods of analysis. The results are as follows. Adolescents are wasting their leisure time because of insufficient facilities for productive activities. They use the time, when observed in one week, roaming around downtown, studying in off-school academies, visiting shops and playing in the game rooms. And when observed in a month, they use time meeting friends in coffee shops, visiting restaurants, studying in the libraries, playing in the ground and visiting sports facilities. Adolescents' leisure time were different according to sex, age, father's educational level, mother's occupation, household income, and living area. Students hoped the leisure spares to be located in the neighborhood where they can access easily, and facilities they wanted were small shop-buildings, game rooms, off-school academies, schools, sports facilities, studying moms and libraries. It is necessary that adolescents have opportunities to learn how to use their leisure time healthy in the leisure space. And consideration on adolescents living in the remote rural area have to be dealt importantly in the beginning of various planning.

• 대한구순구개열학회지
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• 제4권2호
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• pp.69-78
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• 2001

Alveolar cleft exists in 75% of cleft patients, In alveolar cleft patients, alar base is widening, palatal fistular formation, maxillary growth disturbance & tooth loss of adjacent area is raised, Alveolar bone grafting, especially iliac bone grafting, is a general treatment method. As operation timing, bone grafting is classified with primary, early secondary, secondary, & late secondary, Here we report cleft width, marginal bone height, bone resorption rate, grafted shape & bone densities after secondary iliac bone grafting was done in the Dept. of oral and maxillofacial surgery of chonbuk national university hospital. We compared cleft width to bone resorption rate and grafted shape. Also, alveolar bone densities of grafted and contralateral site was compared with Emago 3 package? (Oral Diagonostic System, The Netherlands), The data obtained were analyzed using Spearman's rho coefficients and sign test with SPSS for window, The results were obtained as follows. 1. As alveolar cleft width is increase, bone resorption rate is, too. This relation showed significant difference(P<.01). 2, In proximal & distal area, alvolar cleft width and bone graft contour after bone grafting had a reverse proportional difference. It was not significant difference(P>.05). 3. After 3 month, in bone density results by using Emago 3 package? with periapical standard view, occlusal view & panoramic view, differences between grafted bone and alveolar bone of contralateral site didn't show a significant difference(P>.05). Thus, differences of bone densities in the alveolar bones didn't exist.

• 한국의류학회지
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• 제30권7호
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• pp.1090-1102
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• 2006

The purpose of this study is to develop an improved work clothing which is much safe, comfortable, mobility and convenient than what workers currently wear at construction site. The investigation has been conducted to evaluate current work clothing to grasp any problems, discomforts and damages related to the work clothing. For the best and accurate data, hands-on investigation and a short-interview have been performed at the construction site as well as formulating a questionnaire. The questionnaires was answered by 425 workers and safety manager of 13 different construction site. The result of the questionnaire enables us to design a sample work clothing, many pa π s such as material, pattern and design have been improved. To improve the amenity of heat, the surface of a material was used by $Aerocool^{\circledR}$ fiber which contains inside dryness function. In order to absorb perspiration on the back the armpits, mesh martial that is mixture of $Coolever^{TM}$ fiber and $Mirawave^{TM}$ fiber was used to absorb perspiration in an effective manner. And a sleeve's bottom part and trousers' bottom part's cover method have been changed. Sample work clothing was shorten at the side of upper garment up to 2cm and lengthen the length of the back by 3cm. To reduce the tightness around armpit more room was given in that area. Darts were added to the elbow, the hip, and the knees that also followed an ergonomic pattern. A sample work clothing evaluated an objective assessment and subjective assessment to compare to a current work clothing. Assessment group consists of seven subject groups and nine expert groups to evaluate external appearance and adaptability to the movements. In all aspects of the test, the result of evaluation process of the sample work clothing received more positive assessment than the current work clothing.