• 제목/요약/키워드: Scavenging

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Antioxidant and free radical scavenging activities of Cleome rutidosperma

  • Bose, Anindya;Mondal, Sumanta;Gupta, Jayanta Kumar;Ghosh, Tirtha;Debbhuti, Debabrata;Si, Sudam
    • Advances in Traditional Medicine
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    • 제8권2호
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    • pp.135-145
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    • 2008
  • The study was aimed at evaluating the antioxidant and free radical scavenging activities of ethanolic extract and its fractions of Cleome rutidosperma. The antioxidant activity, reducing power, total phenolic content, total flavonoid content, superoxide anion scavenging activity, nitric oxide anion scavenging activity, in vitro antilipid peroxidation activity and in vitro non-enzymatic hemoglobin glycosylation were studied. The results obtained in the study indicate that Cleome rutidosperma is a potential source of natural antioxidant. All the parameters were found to be concentration dependent and increased with increasing amounts of sample. Flavonoids, phenolic compound like tannins, terpenoids may be responsible for the antioxidant activity of the plant. Variation of solubility parameters in various models may be attributed to non-linearity of activity of ethanol extract fractions models. Further investigation on the isolation and identification of antioxidant component(s) in the plant may lead to chemical entities with potential for clinical use.

Modeling Study on Dispersion and Scavenging of Traffic Pollutants at the Location Near a Busy Road

  • Ma, Chang-Jin
    • Asian Journal of Atmospheric Environment
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    • 제9권4호
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    • pp.272-279
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    • 2015
  • The information about the dispersion and scavenging of traffic-related pollutants at the locations near busy expressways is very helpful to highway planners for developing better plans to reduce exposures to air pollution for people living as well as children attending schools and child care centers near roadways. The objective of the current study was to give information in the dispersion and scavenging of vehicle-derived pollutants at the region near a busy urban expressway by a combination of two different model calculations. The modified Gaussian dispersion model and the Lagrange type below-cloud scavenging model were applied to evaluate $NO_x$ dispersion and DEP (Diesel exhaust particles) wet removal, respectively. The highest $NO_x$ was marked 53.17 ppb within 20-30 meters from the target urban expressway during the heaviest traffic hours (08:00AM-09:00AM) and it was 2.8 times higher than that of really measured at a nearby ambient measuring station. The calculated DEP concentration in size-resolved raindrops showed a continuous decreasing with increasing raindrop size. Especially, a noticeable decrease was found between 0.2 mm and 1.0 mm raindrop diameter.

황기약침액(黃耆藥鍼液)의 NO, DPPH 소거(消去) 및 IL-4 억제효과(抑制效果) (Scavenging Effect on NO, DPPH and Inhibitory Effect on IL-4 in Astragali Radix Herbal-Acupuncture Solution)

  • 이경민;서정철;한상원
    • Journal of Acupuncture Research
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    • 제20권2호
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    • pp.184-194
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    • 2003
  • Objective : This study was designed fo find out whether Astragali Radix Herbal-Acupuncture Solution(ARHA) can scavenge NO, DPPH and IL-4 or not. Astragali Radix has been clinically used to reforce the depression of immune reponse etc. in Oriental Medicine. Methods : Free radical metabolism seems to occupy a remarkably common position in the mechanisms of ageing and ageing related disease. Oxidative damage to DNA, lipids, proteins and other molecules may contribute to the development of cancer, cardiovascular disease and possibly neurodegenerative disease. The effects of ARHA on NO, DPPH and IL-4 were measured. Results : The followings are the summary of the result; (1) There is a significant scavenging effect of ARHA on NO in 1, $10mg/m{\ell}$ group in after 24hrs. (2) There is no significant scavenging effect of ARHA on DPPH. (3) There is a significant scavenging effect of ARHA on IL-4 in 1, $10,100{\mu}g/m{\ell}$ group. Conclusions : These results suggest that ARHA has significant scavenging effect on NO, IL-4 and not on DPPH. This study shows that ARHA can be used for ageing related disease and further studies are required to investigate the antioxidative effects of it.

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바질의 항산화 물질 측정에 관한 연구 (Measurement of Antioxidation Substances in Basil)

  • 서봉순;박명희
    • 동아시아식생활학회지
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    • 제20권1호
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    • pp.54-59
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    • 2010
  • Basil is known to contain six types of polyphenols that engage in physiological activation; protocateuic acid, caffeic acid, chlorogenic acid, courmaric acid, rosmarinic acid and quercetin. In this study, the antioxidants in eight types of basil were evaluated. Specifically, the antioxidative activation of basil was evaluated based on the relationship between active oxygen scavenging (DPPH radical-scavenging), which was used as an index showing the content and functionality of the polyphenol compounds in basil, and $Fe^{2+}$/ascorbate (FTC) and 2-thiobarbituric acid (TBA). The total polyphenol content of the different types basil occurred in the following order: Dark-opal> Lettuce> Bush> Greek> Lemon> Sweet> Geno> Holy. The highest content Dark-opal was 173.3 mg, which was about three times greater than the lowest content Holy, which was 49.85 mg. In addition, DPPH radical-scavenging by Dark-opal 51%, which was the highest scavenging activity occurred in the folling order: Dark-opal> Lettuce> Bush> Greek> Lemon> Sweet> Geno> Holy. The antioxidative activation values measured using the FTC and TBA were the same as the value obtained using the DPPH method. Finally, the level of antioxidative activation measured using FTC, TBA and DPPH methods showed that the higher the content of polyphenol substance was, the stronger the antioxidative activation became.

Antioxidant Properties of Different Polysaccharides Extracted with Water and Sodium Hydroxide from Rice Bran

  • Zha, Xue-Qiang;Luo, Jian-Ping;Zhang, Lei;Hao, Jie
    • Food Science and Biotechnology
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    • 제18권2호
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    • pp.449-455
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    • 2009
  • The antioxidant properties of water extracted polysaccharides (PW), 1%(w/v) NaOH extracted polysaccharides (PN1), and 5%(w/v) NaOH extracted polysaccharides (PN5) were assessed in this paper. PW showed good capability of scavenging $H_2O_2$, anti-lipid peroxidation, reduction power, and scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH). The maximum values were all observed at the dose of 1 mg/mL sample. As far as the antioxidant activities of PN1 were concerned, the capability of scavenging superoxide radical, chelating metal, and total antioxidation showed higher than those of PN5. When polysaccharide concentration was 1 mg/mL, the 3 index described above were attached 71.8%, 51.6%, and $446.3{\mu}M$ Trolox equivalent, respectively. With respect to PN5, higher capabilities of scavenging hydroxyl free radicals were obtained while the peak of 84.8% was observed at the concentration of 1.0 mg/mL. Moreover, the concentration-dependent influences were characterized in all cases.

정향 열수 및 에탄올 추출물의 항산화 및 항염 효과 (Antioxidant and Anti-Inflammatory Activities of Extracts from Eugenia caryophyllata Thunb.)

  • 오희경
    • 한국식생활문화학회지
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    • 제31권5호
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    • pp.481-488
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    • 2016
  • The objective of this study was to investigate the antioxidant and anti-inflammatory activities of Eugenia caryophyllata Thunb. water and 70% ethanol extracts. The content of total polyphenol was significantly higher in water extract than in 70% ethanol extract. The DPPH radical scavenging activity of water extract was similar to that of Vit. C at a concentration of $1,000{\mu}g/mL$. The ABTS radical scavenging activities of water and 70% ethanol extract were similar to that of Vit. C at a concentration of $1,000{\mu}g/mL$. SOD-like activity of water extract was higher than that of 70% ethanol extract at a concentration of $1,000{\mu}g/mL$ but lower than that of Vit. C. The DPPH radical scavenging activity, ABTS radical scavenging activity, and SOD-like activity increased as concentrations of water and 70% ethanol extracts increased. Cell cytotoxicity was not observed at all concentrations except at $100{\mu}g/mL$ concentration of water extract. Inhibitory activity on NO production effect of water extract was significantly higher than that of 70% ethanol extract. These results show that E. caryophyllata Thunb. has potent biological activities, and their activities were different depending on extraction solvent.

현미의 산패 억제를 위한 항산화 및 산소제거능 향낭 개발 (Development of Antioxidant and Oxygen Scavenging Sachets to Prevent the Rancidity of Brown Rice)

  • 이정수;한재준
    • 한국포장학회지
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    • 제21권1호
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    • pp.41-47
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    • 2015
  • 본 연구에서는 현미의 산패를 방지하기 위한 향낭을 개발하고, 이를 실제 현미포장에 적용하여 그 효과를 알아보고자 하였다. 이를 위해 항산화 활성을 가지는 것으로 확인된 allyl mercaptan으로 향낭을, 산소제거능이 있는 sodium L-ascorbate를 주원료로 이용해 산소제거능 향낭을 제조하여 현미포장에 적용하였다. 현미포장 내부에 allyl mercaptan 향낭 또는 산소제거능 향낭을 넣은 후 4주간의 저장기간 동안 1주일 간격으로 산가와 과산화물가를 측정함으로써 현미의 산화안정성을 살펴보았다. 그 결과, sodium L-ascorbate를 기반으로 한 산소제거능 향낭은 무처리구와 비교하여 유의적인 산패 억제 효과를 보였다. 이는 시판중인 철계 산소제거제와 유사한 성능이었다. 그러나 allyl mercaptan 향낭은 현미의 산패를 억제하는데 별다른 효과가 없는 것으로 확인되었다.

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Quantification of Quercetin in Different Parts of Onion and Its DPPH Radical Scavenging and Antibacterial Activity

  • Kim, Su-Jeong;Kim, Gun-Hee
    • Food Science and Biotechnology
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    • 제15권1호
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    • pp.39-43
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    • 2006
  • Levels of quercetin in different parts of onion were investigated using high performance liquid chromatography (HPLC) and liquid chromatography mass spectrometry (LC/MS) suitable for use with functional food material. Two main peaks were observed on HPLC chromatograms from the extracts of the skin, and the outer, middle, and core parts of onion. Using LC/MS, peak 1 was tentatively identified as quercetin monoglucoside at m/z 466.4, and peak 2 as quercetin with [M]+ at m/z 303.3. The levels of quercetin in the skin, and the outer, middle and core parts of the plant were 16.83,2.67,0.95, and 0.35 mg/g, respectively. In the study of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, skin, the nonedible part, contained the highest amount of quercetin, compared to the other edible parts, and showed the highest DPPH radical scavenging activity. Levels of quercetin and DPPH radical scavenging activity increased from core to skin. All parts of onion exhibited the strongest antibacterial activity only against Staphylococcus aureus and Vibro parahaemolyticus. Antibacterial activities of onion exhibited that S. aureus was more sensitive than V. parahaemolyticus. Among the four onion extracts, the middle part showed the strongest inhibitory activity against S. aureus but all onion extracts showed similar antibacterial activities against V. parahaemolyticus.

배기계 형상이 과급기를 장착한 4실린더 디젤엔진의 소기성능에 미치는 영향에 관한 연구 (A Study on the Effect of Exhaust System Configuration on Scavenging Characteristic of a Four-Cylinder Turbocharged Diesel Engine)

  • 정수진;정재우;강우;김우승
    • 한국자동차공학회논문집
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    • 제14권3호
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    • pp.35-43
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    • 2006
  • A four-stroke four-cylinder turbocharged diesel engine can be fitted with various types exhaust system. In this paper, the impacts of exhaust system design on scavenging performance and wave action characteristic during valve overlap are investigated by using one-dimensional gas dynamic code. This work shows that a huge reflected exhaust pressure waves which reaches the exhaust port during valve overlap period is crucial design factor which determines quality and quantity of the fresh charge. Hence pressure wave that reaches the exhaust port of the cylinder during the valve overlap sequence should be weakened for good scavenging performance. This paper describes advantages and disadvantages of the various exhaust systems applied to a turbocharged and intercooled 4-cylinder diesel engine system in terms of scavenging efficiency and engine performance. To verify the computational results, experimental comparison has also performed.

Roasting and Cryogenic Grinding Enhance the Antioxidant Property of Sword Beans (Canavalia gladiata)

  • Jung, Ju-Yeong;Rhee, Jin-Kyu
    • Journal of Microbiology and Biotechnology
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    • 제30권11호
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    • pp.1706-1719
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    • 2020
  • The objective of this study was to optimize the conditions for enhancing the antioxidant properties of sword bean (Canavalia gladiata) as a coffee substitute in two processing methods, roasting and grinding. The optimum conditions for removing off-flavor of the bean and maximizing functionality and efficiency were light roasting and cryogenic grinding (< 53 ㎛). In these conditions, extraction yield was 16.75%, total phenolic content (TPC) was 69.82 ± 0.35 mg gallic acid equivalents/g, and total flavonoid content (TFC) was 168.81 ± 1.64 mg quercetin equivalents/100 g. The antioxidant properties were 77.58 ± 0.27% for DPPH radical scavenging activity and 58.02 ± 0.76 mg Trolox equivalents/g for ABTS radical scavenging activity. The values for TFC and ABTS radical scavenging activity were significantly higher (p < 0.05) than in other conditions, and TPC and DPPH radical scavenging activity were second highest in lightly roasted beans, following raw beans. HS-SPME/GC-MS analysis confirmed that the amino acids and carbohydrates, which are the main components of sword bean, were condensed into other volatile flavor compounds, such as derivatives of furan, pyrazine, and pyrrole during roasting. Roasted and cryogenically ground (cryo-ground) sword beans showed higher functionality in terms of TFC, DPPH, and ABTS radical scavenging activities compared to those of coffee. Overall results showed that light roasting and cryogenic grinding are the most suitable processing conditions for enhancing the bioactivity of sword beans.