• Molecules and Cells
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• v.44 no.11
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• pp.843-850
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• 2021

The rapid increase in collateral omics and phenotypic data has enabled data-driven studies for the fast discovery of cancer targets and biomarkers. Thus, it is necessary to develop convenient tools for general oncologists and cancer scientists to carry out customized data mining without computational expertise. For this purpose, we developed innovative software that enables user-driven analyses assisted by knowledge-based smart systems. Publicly available data on mutations, gene expression, patient survival, immune score, drug screening and RNAi screening were integrated from the TCGA, GDSC, CCLE, NCI, and DepMap databases. The optimal selection of samples and other filtering options were guided by the smart function of the software for data mining and visualization on Kaplan-Meier plots, box plots and scatter plots of publication quality. We implemented unique algorithms for both data mining and visualization, thus simplifying and accelerating user-driven discovery activities on large multiomics datasets. The present Q-omics software program (v0.95) is available at http://qomics.sookmyung.ac.kr.

• Journal of Microbiology and Biotechnology
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• v.27 no.10
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• pp.1808-1819
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• 2017

Knowledge on the functional characteristics and temporal variation of anaerobic bacterial populations is important for better understanding of the microbial process of two-stage anaerobic reactors. However, owing to the high diversity of anaerobic bacteria, close attention should be prioritized to the frequently abundant bacteria that were defined as core bacteria and putatively functionally important. In this study, using MiSeq sequencing technology, the core bacterial community of 98 operational taxonomic units (OTUs) was determined in a two-stage upflow blanket filter reactor treating pharmaceutical wastewater. The core bacterial community accounted for 61.66% of the total sequences and accurately predicted the sample location in the principal coordinates analysis scatter plot as the total bacterial OTUs did. The core bacterial community in the first-stage (FS) and second-stage (SS) reactors were generally distinct, in that the FS core bacterial community was indicated to be more related to a higher-level fermentation process, and the SS core bacterial community contained more microbes in syntrophic cooperation with methanogens. Moreover, the different responses of the FS and SS core bacterial communities to the temperature shock and influent disturbance caused by solid contamination were fully investigated. Co-occurring analysis at the Order level implied that Bacteroidales, Selenomonadales, Anaerolineales, Syneristales, and Thermotogales might play key roles in anaerobic digestion due to their high abundance and tight correlation with other microbes. These findings advance our knowledge about the core bacterial community and its temporal variability for future comparative research and improvement of the two-stage anaerobic system operation.

• Journal of Environmental Science International
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• v.25 no.2
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• pp.217-229
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• 2016

The government has conducted a plan of total maximum daily loads(TMDL), which divides with unit watershed, for management of stable water quality target by setting the permitted total amount of the pollutant. In this study, BOD concentration trends over the last 10 years from 2005 to 2014 were analyzed in the Geumho river. Improvement effect of water quality throughout the implementation period of TMDL was evaluated using the seasonal Mann-Kendall test and a LOWESS(locally weighted scatter plot smoother) smooth. As a study result of the seasonal Mann-Kendall test and the LOWESS smooth, BOD concentration in the Geumho river appeared to have been reduced or held at a constant. As a result of quantitatively analysis for BOD concentration with exploratory data analysis(EDA), the mean and the median of BOD concentration appeared in the order of GH8 > GH7 > GH6 > GH5 > GH4 > GH3 > GH2 > GH1. The monthly average concentration of BOD appeared in the order of Apr > Mar > Feb >May > Jun > Jul > Jan > Aug > Sep > Dec > Nov > Oct. As a result of the outlier, its value was the most frequent in February, which is estimated 1.5 times more than July, and was smallest frequent in July. The outlier in terms of water quality management is necessary in order to establish a management plan for the contaminants in watershed.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.149-152
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• 2005

A new methodology to detect forest fire burnt scars at near real time using MODIS (Moderate-resolution Imaging Spectroradiometer) data is presented here with a goal of introducing a new and improved capability to detect forest fire burnt scars in Thailand. This new technology is expected to increase the efficiency and effectiveness of the forest fire tackling resources distribution and management of the country. Using MODIS data in burnt scars detection has two major advantages - high availability of data and high resolution per performance ratio. Results prove the near real time algorithm suitable and working well in order to monitor the forest fire dynamic movement. The algorithm is based on the threshold separated linear equation of burnt and un-burnt. A ground truth experiment confirms the burnt and un-burnt? areas characteristics (temperature and NDVI). A threshold line on a scatter plot of Band I and Band 2 is determined to separate the burnt from un-burnt pixels. The different threshold values of NDVI and temperature use to identify pixels' anomaly, abnormal low NDVI and high temperature. The overlay (superimpose) method is used to verify burnt pixels. Since forest fire is a dynamic phenomenon, MODIS burnt scars information is suiting well to fill in the missing temporal information of LANDSAT for the forest fire control managing strategy in Thailand. This study was conducted in the Huai-Kha-Kaeng (HKK) Wildlife Sanctuary, Thailand

• Journal of the Korean housing association
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• v.21 no.1
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• pp.53-65
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• 2010

Apartment buildings represent the most typical patterns of housing in Korea. The present plans are very different from the previous ones when they appeared for the first time. Although apartment unit plans has changed drastically, they can be classified into several categories. Apartment unit plans reflects the demands of living activities and space dimensions of unit plans have the characteristics of diachronic continuity and carry the values of living culture. Thus this study aims to provide the statistical dimensional data of each room that can be actually used for the design of unit plans by sub-grouping typical unit plans. The statistical data of this study showed that apartment unit plans are shifting from 2bay/3room type to 3bay/3room type in 1990s. It is very peculiar that the typical unit plan of $60\;m^2$ area becomes to resemble that of $85\;m^2$ area. The space arrangement of typical unit plans of both $60\;m^2$ and $85\;m^2$ area is almost identical while only their space dimensions differ slightly. As the mean/mode/median values of space dimensions in a typical unit plan are converging into a range of narrow margin, space dimensions of typical unit plan are contended to be strictly regular. The statistical numeric data of various space dimensions provided in this paper can be applied practically to the design of apartment unit plans for low income class people who are disprivileged in the society.

• The Korean Journal of Community Living Science
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• v.18 no.3
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• pp.455-467
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• 2007

Recently, there has been a gradual growth of retired in-migrants in high-amenity, rural areas in Korea. However, little has known about that the retirement migration is a blessing or a blight for a local economy in Korea. Therefore, in this study, we intend to explore the relationship between retirement migration and economic development of rural communities in Korea. For this purpose, we used the 1995 and 2000 census data and annual regional statistics for 138 counties in Korea. Based on the previous empirical studies, economic development was measured by 3 indicators such as GRDP (Gross Regional Domestic Product), job creation in the wholesale and retail sector, and the increase of local tax. Also, cross-tab, scatter plot, and correlation were analyzed using the SPSS Windows Program. The finding are as follows: First, from 1995 to 2000, nearly 11 percent of rural counties showed 10 percent and over increase of in-migration rate among retirees. Second, correlation statistics showed a close relationship between retirement in-migrant flows and economic resurgence. In particular, retirement in-migration rates were significantly tied to the job creation of the wholesale and retail sector (r=.19, p<.05) as well as car ownership rate (r=.58, p<.001) resulting in the increase of local tax. However, there was non-significantly positive correlation between retirement in-migrant flows and GRDP change (r=.13). Knowledge of these relationships will be important to policy-makers and for understanding the role that retirement in-migration play in stimulating economic growth of rural communities in Korea.

• Physical Therapy Korea
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• v.17 no.2
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• pp.33-42
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• 2010

The aim of this study was to investigate correlations of the Trunk Control Test (TCT), Postural Assessment Scale for Stroke (PASS-TC), and Trunk Impairment Scale (TIS) and to compare the TCT, PASS-TC, TIS and its subscales in relation to balance, gait and functional performance ability after stroke. Sixty-two stroke patients attending a rehabilitation program participated in the study. Trunk control was measured with the use of TCT, PASS-TC, TIS balance (Berg Balance scale; BSS), gait ability (10 m walk test), functional performance ability (Tuned Up and Go Test TUG) and the mobility part of the Modified Barthel index (MBI), Fugl Meyer-Upper/Lower Extremity ($FM-U{\cdot}L/E$), The scatter-plot (correlation coefficient) was composed for the total scores of the TCT, PASS-TC, and TIS. The multiple regression analysis was performed to evaluate the impact of trunk control on balance, gait, and functional performance ability. Twenty eight participants (45.2%) and twenty participants (32.3%) obtained the maximum score on the TCT and PASS-TC respectively; no subject reached the maximum score on the Trunk Impairment Scale. There were significant correlations between the TIS and TCT (r=.38, p<.01), PASS-TC (r=.30, p<.05), TCT and PASS-TC (r=.59, p<.01). Stepwise multiple regression analysis showed that the BBS score (${\beta}=.420{\sim}.832$) had slightly more power in predicting trunk control than the $FM-U{\cdot}L/E$. TIS-dynamic sitting balance, TUG and the MBI-mobility part. This study 치early indicates that trunk control is still impaired in stroke patients. Measures of trunk control were significantly related with values of balance, gait and functional performance ability. The results imply that management of trunk rehabilitation after stroke should be emphasized.

• Journal of Korean Academy of Nursing Administration
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• v.17 no.2
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• pp.168-179
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• 2011

Purpose: The purpose of this study was to identify level of recognition of the importance, satisfaction and contribution of APNs' role by physicians, nurses, and advanced practice nurses. Method: Perceived importance and satisfaction were measured with a 23-item questionnaire on APN role with 5 subcategories. APNs' contribution was investigated using a 13-item outcome questionnaire developed by the researchers. Between August 15 and October 31, 2009, the researchers collected data from 68 physicians, 265 nurses, and 23 APNs all working in a single tertiary hospital. Data were analyzed using descriptive statistics, Kruskal-Wallis Test with Bonferroni's Correction and scatter plot. Result: The importance (3.24~3.39, 4 point scale), satisfaction (3.02~3.13, 4 point scale), and contribution of APNs' role (3.39~4.12, 5 point scale) were well recognized by the health care professionals. All the three health care professional groups rated APNs' contribution high in medical service management, continuity of care, patient accessibility, improvement in patient satisfaction, and patient and family education. 'Importance-Satisfaction Analysis' showed that patient data management by APNs needed greater effort. Conclusions: The findings show that the importance, satisfaction, contribution of APNs' role are recognized, and indicate a need for further development of APNs' role through efforts to overcome the gaps identified through this research.

• Korean Journal of Remote Sensing
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• v.27 no.3
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• pp.303-314
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• 2011

Surface albedo is an important parameter of the surface energy budget, and its accurate quantification is of major interest to the global climate modeling community. Therefore, in this paper, we consider the direct solution of kernel based bidirectional reflectance distribution function (BRDF) models for retrieval of normalized reflectance of high resolution satellite. The BRD effects can be seen in satellite data having a wide swath such as SPOT/VGT (VEGETATION) have sufficient angular sampling, but high resolution satellites are impossible to obtain sufficient angular sampling over a pixel during short period because of their narrow swath scanning when applying semi-empirical model. This gives a difficulty to run BRDF model inferring the reflectance normalization of high resolution satellites. The principal purpose of the study is to estimate normalized reflectance of high resolution satellite (RapidEye) through BRDF components from SPOT/VGT. We use semi-empirical BRDF model to estimated BRDF components from SPOT/VGT and reflectance normalization of RapidEye. This study used SPOT/VGT satellite data acquired in the S1 (daily) data, and within this study is the multispectral sensor RapidEye. Isotropic value such as the normalized reflectance was closely related to the BRDF parameters and the kernels. Also, we show scatter plot of the SPOT/VGT and RapidEye isotropic value relationship. The linear relationship between the two linear regression analysis is performed by using the parameters of SPOTNGT like as isotropic value, geometric value and volumetric scattering value, and the kernel values of RapidEye like as geometric and volumetric scattering kernel Because BRDF parameters are difficult to directly calculate from high resolution satellites, we use to BRDF parameter of SPOT/VGT. Also, we make a decision of weighting for geometric value, volumetric scattering value and error through regression models. As a result, the weighting through linear regression analysis produced good agreement. For all sites, the SPOT/VGT isotropic and RapidEye isotropic values had the high correlation (RMSE, bias), and generally are very consistent.

• Journal of Korean Society on Water Environment
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• v.33 no.1
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• pp.40-50
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• 2017

We were interested in the long-term temporal and spatial variability trends of water quality. Trend tests such as the Seasonal and Regional Kendall tests and LOWESS (LOcally WEighted Scatter plot Smoother) have been recommended as outstanding tools for trend detection. In this study, we conducted four types of nonparametric trend tests (Seasonal and Regional Kendall tests, LOWESS, and flow-adjusted Seasonal Kendall). We aimed to identify water quality trends using the monthly data for five variables (BOD, COD, TN, TP, and flow) collected from 24 sites in the Nakdong River from August 2004 to December 2013. According to the Regional Kendall test, BOD, COD, and TN increased but TP decreased trend. The Seasonal Kendall test showed that BOD, TN, and TP remained constant at 62.5-83.3% of the sites. COD remained constant at 58.3% of the sites. LOWESS showed that TP gradually increased between 2007 and 2008, then decreased slowly at the Gumi, Geumhogang6, Daeam-1 and Milyanggang3 sites. BOD increased slightly between 2008 and 2009, and then decreased slowly at the Namgang4-1 site. Lastly, a flow-adjusted Seasonal Kendall test was conducted. There were different results between Seasonal Kendall and flow-adjusted Seasonal Kendall tests at 11 of the 24 sites. According to the results from six of the eleven sites, BOD increased at one site, showed no trends at three sited, and decreased at two sites. Each of COD, TN increased at two, one site. but TP decreased at two sites.